JP6126197B2 - ＰＩ３Ｋ−α及び／又はβの阻害剤としてのボロン酸をもったリファゲイン化合物 - Google Patents

ＰＩ３Ｋ−α及び／又はβの阻害剤としてのボロン酸をもったリファゲイン化合物 Download PDF

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JP6126197B2
JP6126197B2 JP2015501053A JP2015501053A JP6126197B2 JP 6126197 B2 JP6126197 B2 JP 6126197B2 JP 2015501053 A JP2015501053 A JP 2015501053A JP 2015501053 A JP2015501053 A JP 2015501053A JP 6126197 B2 JP6126197 B2 JP 6126197B2
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JP2015514701A5 (https=
JP2015514701A (ja
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ラム アスレイ ヴィシュワカルマ
ラム アスレイ ヴィシュワカルマ
サンハパル ダモダール サワント
サンハパル ダモダール サワント
パーヴィンダー パル シング
パーヴィンダー パル シング
アビド ハミド ダル
アビド ハミド ダル
パルドゥマン ラジュ シャルマ
パルドゥマン ラジュ シャルマ
アジト クマール サクゼナ
アジト クマール サクゼナ
アミット ナルゴトラ
アミット ナルゴトラ
アンジャネヤ アラヴィンド クマール コルル
アンジャネヤ アラヴィンド クマール コルル
ラメッシュ ムドゥドゥドラ
ラメッシュ ムドゥドゥドラ
アシフ クールシッド クァジ
アシフ クールシッド クァジ
アーシク フサイン
アーシク フサイン
ナヤン チャナウリア
ナヤン チャナウリア
Original Assignee
カウンシル オブ サイエンティフィック アンド インダストリアル リサーチ
カウンシル オブ サイエンティフィック アンド インダストリアル リサーチ
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic Table
    • C07F5/02—Boron compounds
    • C07F5/025—Boronic and borinic acid compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/69—Boron compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
JP2015501053A 2012-03-19 2013-03-18 ＰＩ３Ｋ−α及び／又はβの阻害剤としてのボロン酸をもったリファゲイン化合物 Expired - Fee Related JP6126197B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
IN0794/DEL/2012 2012-03-19
IN794DE2012 IN2012DE00794A (https=) 2012-03-19 2013-03-18
PCT/IN2013/000169 WO2013140417A1 (en) 2012-03-19 2013-03-18 BORONIC ACID BEARING LIPHAGANE COMPOUNDS AS INHIBITORS OF PI3K-α AND/OR β

Publications (3)

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JP2015514701A JP2015514701A (ja) 2015-05-21
JP2015514701A5 JP2015514701A5 (https=) 2016-05-19
JP6126197B2 true JP6126197B2 (ja) 2017-05-10

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JP2015501053A Expired - Fee Related JP6126197B2 (ja) 2012-03-19 2013-03-18 ＰＩ３Ｋ−α及び／又はβの阻害剤としてのボロン酸をもったリファゲイン化合物

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Country Link
US (1) US9206201B2 (https=)
EP (1) EP2828269B1 (https=)
JP (1) JP6126197B2 (https=)
CN (1) CN104395325B (https=)
CA (1) CA2867452C (https=)
IN (1) IN2012DE00794A (https=)
TW (1) TWI577687B (https=)
WO (1) WO2013140417A1 (https=)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3199090B2 (ja) 1993-10-19 2001-08-13 東芝ライテック株式会社 放電灯点灯装置

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2018203564A1 (ja) 2017-05-02 2018-11-08 国立大学法人東北大学 リファガールの類縁体、及びリファガール又はその類縁体を含む多標的キナーゼ阻害剤
JP2019099537A (ja) * 2017-12-07 2019-06-24 コニカミノルタ株式会社 含窒素複素環化合物の製造方法
WO2024222697A1 (zh) * 2023-04-23 2024-10-31 纽欧申医药(上海)有限公司 一种含氮多元环化合物、其制备方法及应用

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006081659A1 (en) * 2005-02-01 2006-08-10 The University Of British Columbia Meroterpenoid inhibitors of phosphoinositide 3 kinase (pi3k)
GB2465405A (en) * 2008-11-10 2010-05-19 Univ Basel Triazine, pyrimidine and pyridine analogues and their use in therapy

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3199090B2 (ja) 1993-10-19 2001-08-13 東芝ライテック株式会社 放電灯点灯装置

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Publication number Publication date
IN2012DE00794A (https=) 2015-08-21
US20150051173A1 (en) 2015-02-19
CA2867452C (en) 2020-04-14
EP2828269A1 (en) 2015-01-28
WO2013140417A4 (en) 2013-11-21
WO2013140417A1 (en) 2013-09-26
JP2015514701A (ja) 2015-05-21
EP2828269B1 (en) 2018-05-16
TW201341391A (zh) 2013-10-16
TWI577687B (zh) 2017-04-11
CN104395325B (zh) 2016-12-07
CN104395325A (zh) 2015-03-04
CA2867452A1 (en) 2013-09-26
US9206201B2 (en) 2015-12-08

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