TWI577687B - 作為ＰＩ３Ｋ－α及／或β抑制劑之帶有硼酸之立費烷（ＬＩＰＨＡＧＡＮＥ）化合物 - Google Patents

作為ＰＩ３Ｋ－α及／或β抑制劑之帶有硼酸之立費烷（ＬＩＰＨＡＧＡＮＥ）化合物 Download PDF

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Publication number
TWI577687B
TWI577687B TW102109708A TW102109708A TWI577687B TW I577687 B TWI577687 B TW I577687B TW 102109708 A TW102109708 A TW 102109708A TW 102109708 A TW102109708 A TW 102109708A TW I577687 B TWI577687 B TW I577687B
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Taiwan
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compound
group
formula
methyl
mhz
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TW102109708A
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Chinese (zh)
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TW201341391A (zh
Inventor
蘭阿斯瑞 維斯瓦卡馬
參波達摩哈 薩旺
帕芬德鮑 辛
阿比哈密德 達
帕都曼拉杰 薩瑪
阿傑庫瑪 薩席娜
阿米特 納果塔
安捷亞阿拉芬庫瑪 可陸魯
拉米許 慕都督拉
阿希赫希 奎茲
阿希 胡珊
納楊 恰納里亞
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印度科學與工業研究理事會
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic Table
    • C07F5/02—Boron compounds
    • C07F5/025—Boronic and borinic acid compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/69—Boron compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
TW102109708A 2012-03-19 2013-03-19 作為ＰＩ３Ｋ－α及／或β抑制劑之帶有硼酸之立費烷（ＬＩＰＨＡＧＡＮＥ）化合物 TWI577687B (zh)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IN794DE2012 IN2012DE00794A (https=) 2012-03-19 2013-03-18

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TW201341391A TW201341391A (zh) 2013-10-16
TWI577687B true TWI577687B (zh) 2017-04-11

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TW102109708A TWI577687B (zh) 2012-03-19 2013-03-19 作為ＰＩ３Ｋ－α及／或β抑制劑之帶有硼酸之立費烷（ＬＩＰＨＡＧＡＮＥ）化合物

Country Status (8)

Country Link
US (1) US9206201B2 (https=)
EP (1) EP2828269B1 (https=)
JP (1) JP6126197B2 (https=)
CN (1) CN104395325B (https=)
CA (1) CA2867452C (https=)
IN (1) IN2012DE00794A (https=)
TW (1) TWI577687B (https=)
WO (1) WO2013140417A1 (https=)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3199090B2 (ja) 1993-10-19 2001-08-13 東芝ライテック株式会社 放電灯点灯装置
WO2018203564A1 (ja) 2017-05-02 2018-11-08 国立大学法人東北大学 リファガールの類縁体、及びリファガール又はその類縁体を含む多標的キナーゼ阻害剤
JP2019099537A (ja) * 2017-12-07 2019-06-24 コニカミノルタ株式会社 含窒素複素環化合物の製造方法
WO2024222697A1 (zh) * 2023-04-23 2024-10-31 纽欧申医药(上海)有限公司 一种含氮多元环化合物、其制备方法及应用

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006081659A1 (en) * 2005-02-01 2006-08-10 The University Of British Columbia Meroterpenoid inhibitors of phosphoinositide 3 kinase (pi3k)

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2465405A (en) * 2008-11-10 2010-05-19 Univ Basel Triazine, pyrimidine and pyridine analogues and their use in therapy

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006081659A1 (en) * 2005-02-01 2006-08-10 The University Of British Columbia Meroterpenoid inhibitors of phosphoinositide 3 kinase (pi3k)

Also Published As

Publication number Publication date
IN2012DE00794A (https=) 2015-08-21
US20150051173A1 (en) 2015-02-19
CA2867452C (en) 2020-04-14
EP2828269A1 (en) 2015-01-28
WO2013140417A4 (en) 2013-11-21
WO2013140417A1 (en) 2013-09-26
JP2015514701A (ja) 2015-05-21
EP2828269B1 (en) 2018-05-16
TW201341391A (zh) 2013-10-16
JP6126197B2 (ja) 2017-05-10
CN104395325B (zh) 2016-12-07
CN104395325A (zh) 2015-03-04
CA2867452A1 (en) 2013-09-26
US9206201B2 (en) 2015-12-08

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