JP6090330B2 - センサチップ及び測定システム - Google Patents

センサチップ及び測定システム Download PDF

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Publication number
JP6090330B2
JP6090330B2 JP2014544567A JP2014544567A JP6090330B2 JP 6090330 B2 JP6090330 B2 JP 6090330B2 JP 2014544567 A JP2014544567 A JP 2014544567A JP 2014544567 A JP2014544567 A JP 2014544567A JP 6090330 B2 JP6090330 B2 JP 6090330B2
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JP
Japan
Prior art keywords
flow path
sample
sensor chip
antibody
measurement
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
JP2014544567A
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English (en)
Japanese (ja)
Other versions
JPWO2014069551A1 (ja
Inventor
悠 石毛
悠 石毛
釜堀 政男
政男 釜堀
佑介 後藤
佑介 後藤
淳子 田中
淳子 田中
理子 岩田
理子 岩田
中村 英博
英博 中村
健 澤崎
健 澤崎
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Showa Denko Materials Co Ltd
Original Assignee
Hitachi Chemical Co Ltd
Showa Denko Materials Co Ltd
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Application filed by Hitachi Chemical Co Ltd, Showa Denko Materials Co Ltd filed Critical Hitachi Chemical Co Ltd
Publication of JPWO2014069551A1 publication Critical patent/JPWO2014069551A1/ja
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Expired - Fee Related legal-status Critical Current
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    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502715Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by interfacing components, e.g. fluidic, electrical, optical or mechanical interfaces
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483Physical analysis of biological material
    • G01N33/487Physical analysis of biological material of liquid biological material
    • G01N33/49Blood
    • G01N33/4915Blood using flow cells
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366Apparatus specially adapted for solid-phase testing
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/72Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood pigments, e.g. haemoglobin, bilirubin or other porphyrins; involving occult blood
    • G01N33/721Haemoglobin
    • G01N33/723Glycosylated haemoglobin
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/72Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood pigments, e.g. haemoglobin, bilirubin or other porphyrins; involving occult blood
    • G01N33/721Haemoglobin
    • G01N33/726Devices
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/02Adapting objects or devices to another
    • B01L2200/026Fluid interfacing between devices or objects, e.g. connectors, inlet details
    • B01L2200/027Fluid interfacing between devices or objects, e.g. connectors, inlet details for microfluidic devices
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/06Auxiliary integrated devices, integrated components
    • B01L2300/0627Sensor or part of a sensor is integrated
    • B01L2300/0645Electrodes
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/08Geometry, shape and general structure
    • B01L2300/0809Geometry, shape and general structure rectangular shaped
    • B01L2300/0816Cards, e.g. flat sample carriers usually with flow in two horizontal directions
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/08Geometry, shape and general structure
    • B01L2300/0861Configuration of multiple channels and/or chambers in a single devices
    • B01L2300/0864Configuration of multiple channels and/or chambers in a single devices comprising only one inlet and multiple receiving wells, e.g. for separation, splitting
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00Moving or stopping fluids
    • B01L2400/04Moving fluids with specific forces or mechanical means
    • B01L2400/0403Moving fluids with specific forces or mechanical means specific forces
    • B01L2400/0415Moving fluids with specific forces or mechanical means specific forces electrical forces, e.g. electrokinetic
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2400/00Assays, e.g. immunoassays or enzyme assays, involving carbohydrates
    • G01N2400/02Assays, e.g. immunoassays or enzyme assays, involving carbohydrates involving antibodies to sugar part of glycoproteins

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Pathology (AREA)
  • Biochemistry (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Ecology (AREA)
  • Biophysics (AREA)
  • Dispersion Chemistry (AREA)
  • Clinical Laboratory Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
JP2014544567A 2012-10-31 2013-10-31 センサチップ及び測定システム Expired - Fee Related JP6090330B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2012240010 2012-10-31
JP2012240010 2012-10-31
PCT/JP2013/079486 WO2014069551A1 (fr) 2012-10-31 2013-10-31 Puce de capteur, et dispositif de mesure et procédé de mesure l'utilisant

Publications (2)

Publication Number Publication Date
JPWO2014069551A1 JPWO2014069551A1 (ja) 2016-09-08
JP6090330B2 true JP6090330B2 (ja) 2017-03-08

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JP2014544567A Expired - Fee Related JP6090330B2 (ja) 2012-10-31 2013-10-31 センサチップ及び測定システム

Country Status (2)

Country Link
JP (1) JP6090330B2 (fr)
WO (1) WO2014069551A1 (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10648975B2 (en) 2017-07-03 2020-05-12 Lansion Biotechnology Co., Ltd. Single channel chemiluminescent micro-fluidic chip and detection method thereof

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JP2015087293A (ja) * 2013-10-31 2015-05-07 日立化成株式会社 グリコアルブミンの測定キットおよび測定方法
US10005080B2 (en) * 2014-11-11 2018-06-26 Genmark Diagnostics, Inc. Instrument and cartridge for performing assays in a closed sample preparation and reaction system employing electrowetting fluid manipulation
JP6487190B2 (ja) 2014-11-21 2019-03-20 サントル ナショナル ドゥラ ルシェルシュ シヤンティフィック 分子検出システム
EP4115978A1 (fr) * 2015-01-14 2023-01-11 Pixcell Medical Technologies Ltd. Cartouche jetable pour analyse de liquide d'essai
EP3112869A1 (fr) * 2015-06-30 2017-01-04 IMEC vzw Dispositif de capteur
WO2017082253A1 (fr) * 2015-11-09 2017-05-18 東レ株式会社 Capteur
GB2545009A (en) * 2015-12-03 2017-06-07 Univ Ulster Liquid sample collection apparatus
JP6953679B2 (ja) * 2016-03-30 2021-10-27 ソニーグループ株式会社 試料分取キット、試料分取装置
CN105954524B (zh) * 2016-07-15 2018-06-29 安徽国科生物科技有限公司 用于人热休克蛋白检测的生物芯片
CN106018786B (zh) * 2016-07-15 2018-06-29 安徽国科生物科技有限公司 用于检测降钙素原的智能检测设备
WO2018062320A1 (fr) * 2016-09-30 2018-04-05 京セラ株式会社 Capteur de détection, kit pour capteurs de détection, dispositif capteur, procédé de production d'un capteur de détection et procédé de détection
CN107167619A (zh) * 2017-05-18 2017-09-15 易源易贝(北京)科技有限公司 一种流体试样检测系统和检测方法
WO2019022081A1 (fr) * 2017-07-28 2019-01-31 京セラ株式会社 Module de capteur
CN111556964A (zh) * 2018-01-23 2020-08-18 京瓷株式会社 测定方法、以及测定装置
JP2019190977A (ja) * 2018-04-25 2019-10-31 株式会社バイオデバイステクノロジー マイクロチップおよびマイクロチップ測定システムおよび測定方法
WO2021005642A1 (fr) * 2019-07-05 2021-01-14 日本電信電話株式会社 Dispositif et procédé d'analyse
US20230032773A1 (en) * 2019-12-24 2023-02-02 Vsense Medical Llc Analyte sensing system and cartridge thereof

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JP4044163B2 (ja) * 1995-11-15 2008-02-06 アークレイ株式会社 液体検知方法および器具
JPH1010065A (ja) * 1996-06-21 1998-01-16 Showa Shell Sekiyu Kk イムノセンサ
JP3834357B2 (ja) * 1996-07-10 2006-10-18 オリンパス株式会社 小型分析装置及びその駆動方法
JP2003202347A (ja) * 2002-01-07 2003-07-18 Mitsubishi Heavy Ind Ltd マイクロリアクタ
US7419821B2 (en) * 2002-03-05 2008-09-02 I-Stat Corporation Apparatus and methods for analyte measurement and immunoassay
US20030180814A1 (en) * 2002-03-21 2003-09-25 Alastair Hodges Direct immunosensor assay
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JP3952036B2 (ja) * 2004-05-13 2007-08-01 コニカミノルタセンシング株式会社 マイクロ流体デバイス並びに試液の試験方法および試験システム
JP2006058112A (ja) * 2004-08-19 2006-03-02 Kawamura Inst Of Chem Res 微量試料計量デバイス、微量試料計量装置及び微量試料の計量方法
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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10648975B2 (en) 2017-07-03 2020-05-12 Lansion Biotechnology Co., Ltd. Single channel chemiluminescent micro-fluidic chip and detection method thereof

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WO2014069551A1 (fr) 2014-05-08
JPWO2014069551A1 (ja) 2016-09-08

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