JP6078838B2 - 生体組織の処理方法及び保存用生体組織の製造方法 - Google Patents

生体組織の処理方法及び保存用生体組織の製造方法 Download PDF

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JP6078838B2
JP6078838B2 JP2014508253A JP2014508253A JP6078838B2 JP 6078838 B2 JP6078838 B2 JP 6078838B2 JP 2014508253 A JP2014508253 A JP 2014508253A JP 2014508253 A JP2014508253 A JP 2014508253A JP 6078838 B2 JP6078838 B2 JP 6078838B2
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tissue
biological tissue
sterilizing
biological
trehalose
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JPWO2013147299A1 (ja
Inventor
岩▲崎▼　清隆
清隆 岩▲崎▼
梅津　光生
光生 梅津
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Waseda University
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Waseda University
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A61L2/16—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor using chemical substances
    • A61L2/20—Gaseous substances, e.g. vapours
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00—Preservation of bodies of humans or animals, or parts thereof
    • A01N1/10—Preservation of living parts
    • A01N1/12—Chemical aspects of preservation
    • A01N1/122—Preservation or perfusion media
    • A01N1/125—Freeze protecting agents, e.g. cryoprotectants or osmolarity regulators
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00—Preservation of bodies of humans or animals, or parts thereof
    • A01N1/10—Preservation of living parts
    • A01N1/12—Chemical aspects of preservation
    • A01N1/122—Preservation or perfusion media
    • A01N1/126—Physiologically active agents, e.g. antioxidants or nutrients
    • A61L2103/05—
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/3683—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment
    • A61L27/3687—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment characterised by the use of chemical agents in the treatment, e.g. specific enzymes, detergents, capping agents, crosslinkers, anticalcification agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00—Materials or treatment for tissue regeneration
    • A61L2430/40—Preparation and treatment of biological tissue for implantation, e.g. decellularisation, cross-linking

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Dentistry (AREA)
  • Environmental Sciences (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Botany (AREA)
  • Dermatology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Materials For Medical Uses (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Biophysics (AREA)
  • Physiology (AREA)
JP2014508253A 2012-03-31 2013-04-01 生体組織の処理方法及び保存用生体組織の製造方法 Active JP6078838B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2012083367 2012-03-31
JP2012083367 2012-03-31
PCT/JP2013/059842 WO2013147299A1 (ja) 2012-03-31 2013-04-01 生体組織の処理方法及び生体組織

Publications (2)

Publication Number Publication Date
JPWO2013147299A1 JPWO2013147299A1 (ja) 2015-12-14
JP6078838B2 true JP6078838B2 (ja) 2017-02-15

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JP2014508253A Active JP6078838B2 (ja) 2012-03-31 2013-04-01 生体組織の処理方法及び保存用生体組織の製造方法

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US (1) US10660977B2 (Direct)
EP (1) EP2832376B1 (Direct)
JP (1) JP6078838B2 (Direct)
CN (1) CN104302329A (Direct)
AU (1) AU2013240916B2 (Direct)
ES (1) ES2649904T3 (Direct)
IN (1) IN2014MN01939A (Direct)
WO (1) WO2013147299A1 (Direct)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2023058163A1 (ja) 2021-10-06 2023-04-13 ＣｏｒｅＴｉｓｓｕｅ ＢｉｏＥｎｇｉｎｅｅｒｉｎｇ株式会社 生体組織保管用容器

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CN106190949B (zh) * 2015-05-08 2020-04-10 上海微创心通医疗科技有限公司 一种干态动物源性胶原纤维组织材料及其制备方法和生物假体
CN109549761A (zh) * 2018-09-12 2019-04-02 沛嘉医疗科技(苏州)有限公司 一种人工生物瓣膜及其制备方法
WO2020242967A1 (en) * 2019-05-28 2020-12-03 W. L. Gore & Associates, Inc. Stabilized medical device and method for making it
CN114304181B (zh) * 2021-12-30 2023-04-21 苏州昊本生物科技有限公司 一种灭菌剂及应用灭菌剂的杀菌方法

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US5336616A (en) 1990-09-12 1994-08-09 Lifecell Corporation Method for processing and preserving collagen-based tissues for transplantation
AU650045B2 (en) * 1990-09-12 1994-06-09 Lifecell Corporation Method and apparatus for cryopreparation dry stabilization and rehydration of biological suspensions
US5334841A (en) * 1993-01-22 1994-08-02 Minnesota Mining And Manufacturing Company Method and apparatus for detecting fluorescence
US6632648B1 (en) 1996-05-14 2003-10-14 Elan Drug Delivery Limited Methods of terminal sterilization of fibrinogen
CA2335152C (en) * 1998-05-14 2008-11-18 The Cleveland Clinic Foundation Processing of implantable animal tissues for dry storage
US20030068815A1 (en) * 1999-02-11 2003-04-10 Stone Kevin R. Sterilized xenograft tissue
US6866686B2 (en) * 2000-01-28 2005-03-15 Cryolife, Inc. Tissue graft
US6908591B2 (en) * 2002-07-18 2005-06-21 Clearant, Inc. Methods for sterilizing biological materials by irradiation over a temperature gradient
CN100506295C (zh) 2003-05-01 2009-07-01 北京大清生物技术有限公司 生物衍生骨复合四环素缓释体
CA2527822A1 (en) 2003-05-30 2004-12-23 Stratatech Corporation Room temperature storage of organs
JP2008228744A (ja) 2005-06-23 2008-10-02 Osaka Prefecture Univ 生体由来移植用組織の石灰化を抑制するための処理方法および処理された組織
WO2007013331A1 (ja) * 2005-07-25 2007-02-01 Arblast Co., Ltd. シート状組成物
US9132208B2 (en) * 2008-08-07 2015-09-15 Lifenet Health Composition for a tissue repair implant and methods of making the same
CN101626682B (zh) * 2006-10-27 2014-04-16 爱德华兹生命科学公司 用于外科植入的生物组织
WO2008077155A1 (en) * 2006-12-21 2008-06-26 Genentech, Inc. Sterilization of objects containing biological molecules
WO2008154623A2 (en) * 2007-06-12 2008-12-18 Musculoskeletal Transplant Foundation Process for sterilizing acellular soft tissue with irradiation
US8357387B2 (en) 2007-12-21 2013-01-22 Edwards Lifesciences Corporation Capping bioprosthetic tissue to reduce calcification
CN101366976B (zh) * 2008-09-03 2012-08-29 陕西瑞盛生物科技有限公司 人源化异种细胞外基质材料及其制备方法
JP5424147B2 (ja) 2009-06-26 2014-02-26 学校法人早稲田大学 保存処理時の生体組織の保持方法及び保持具、並びに保存処理された生体組織
EP2464221A4 (en) 2009-08-11 2012-08-01 Tissue Banks Internat CELLULAR DERMALE ALLOTRANSPLANTATE AND MANUFACTURING METHOD THEREFOR
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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2023058163A1 (ja) 2021-10-06 2023-04-13 ＣｏｒｅＴｉｓｓｕｅ ＢｉｏＥｎｇｉｎｅｅｒｉｎｇ株式会社 生体組織保管用容器

Also Published As

Publication number Publication date
US20150064228A1 (en) 2015-03-05
IN2014MN01939A (Direct) 2015-07-10
CN104302329A (zh) 2015-01-21
EP2832376B1 (en) 2017-09-06
US10660977B2 (en) 2020-05-26
JPWO2013147299A1 (ja) 2015-12-14
EP2832376A1 (en) 2015-02-04
WO2013147299A1 (ja) 2013-10-03
AU2013240916B2 (en) 2016-10-27
EP2832376A4 (en) 2015-05-06
AU2013240916A1 (en) 2014-10-16
ES2649904T3 (es) 2018-01-16

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