JP6063392B2 - 自己免疫性障害または臓器免疫拒絶による苦痛を治療するための、インドールアミン−２，３−ジオキシゲナーゼ（ｉｄｏ）を誘導する少なくとも２つの化合物を含んでなる組成物 - Google Patents

自己免疫性障害または臓器免疫拒絶による苦痛を治療するための、インドールアミン−２，３−ジオキシゲナーゼ（ｉｄｏ）を誘導する少なくとも２つの化合物を含んでなる組成物 Download PDF

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JP6063392B2
JP6063392B2 JP2013546073A JP2013546073A JP6063392B2 JP 6063392 B2 JP6063392 B2 JP 6063392B2 JP 2013546073 A JP2013546073 A JP 2013546073A JP 2013546073 A JP2013546073 A JP 2013546073A JP 6063392 B2 JP6063392 B2 JP 6063392B2
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ido
interferon
composition
zebralin
cells
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JP2014500312A (ja
JP2014500312A5 (enExample
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サルフォルド，レイフ
オロフ フェーグレーン，ハンス
オロフ フェーグレーン，ハンス
ヴィーデグレーン，ベント
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Idogen AB
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JP2013546073A 2010-12-22 2011-12-20 自己免疫性障害または臓器免疫拒絶による苦痛を治療するための、インドールアミン−２，３−ジオキシゲナーゼ（ｉｄｏ）を誘導する少なくとも２つの化合物を含んでなる組成物 Expired - Fee Related JP6063392B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
SE1051356 2010-12-22
SE1051356-2 2010-12-22
PCT/SE2011/051544 WO2012087234A1 (en) 2010-12-22 2011-12-20 A composition comprising at least to compounds which induces indolamine 2,3-dioxygenase (ido), for the treatment of an autoimmune disorder or suffering from immune rejection of organs

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JP2014500312A JP2014500312A (ja) 2014-01-09
JP2014500312A5 JP2014500312A5 (enExample) 2015-02-19
JP6063392B2 true JP6063392B2 (ja) 2017-01-18

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JP2013546073A Expired - Fee Related JP6063392B2 (ja) 2010-12-22 2011-12-20 自己免疫性障害または臓器免疫拒絶による苦痛を治療するための、インドールアミン−２，３−ジオキシゲナーゼ（ｉｄｏ）を誘導する少なくとも２つの化合物を含んでなる組成物

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US (3) US20130309198A1 (enExample)
EP (2) EP2654758B1 (enExample)
JP (1) JP6063392B2 (enExample)
CA (1) CA2822745A1 (enExample)
DK (1) DK2654758T3 (enExample)
ES (1) ES2638818T3 (enExample)
PL (1) PL2654758T3 (enExample)
WO (1) WO2012087234A1 (enExample)

Families Citing this family (9)

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Publication number Priority date Publication date Assignee Title
CN105473550B (zh) * 2013-07-01 2019-02-15 百时美施贵宝公司 Ido抑制剂
GB201504701D0 (en) * 2015-03-19 2015-05-06 Idogen Ab Novel treatment method
CN104873731A (zh) * 2015-05-22 2015-09-02 宫兆妮 用于狼疮肾炎的中药
WO2018037108A1 (en) * 2016-08-26 2018-03-01 Idogen Ab Ex vivo methods of inducing ido expression in antigen presenting cells using a compound selected from the group consisting of azacytidine, and decitabine
US11591300B2 (en) 2017-12-21 2023-02-28 The Brigham And Women's Hospital, Inc. Oxazole containing compounds as activators of IDO1 and AhR
US11712425B2 (en) 2018-03-14 2023-08-01 Albert Einstein College Of Medicine Immunoregulatory role of 3-OH-kynurenamine and uses thereof
EP4096720A2 (en) * 2020-01-30 2022-12-07 ModernaTX, Inc. Mrnas encoding metabolic reprogramming polypeptides and uses thereof
WO2024033896A1 (en) * 2022-08-12 2024-02-15 Biorchestra Co., Ltd. Oligonucleotides targeting indoleamine 2,3-dioxygenase and uses thereof
WO2024155564A1 (en) * 2023-01-17 2024-07-25 Regeneron Pharmaceuticals, Inc. Inositol polyphosphate multikinase (ipmk) therapeutic agents or indoleamine 2,3-dioxygenase 2 (ido2) agonists for use in treating b27-negative uveitis

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US6518012B1 (en) * 1999-04-02 2003-02-11 Health Research, Inc. Method for regulating the expression of MHC antigens and CD40 by inhibitors of histone deacetylation
US6613753B2 (en) * 2001-02-21 2003-09-02 Supergen, Inc. Restore cancer-suppressing functions to neoplastic cells through DNA hypomethylation
US6905669B2 (en) 2001-04-24 2005-06-14 Supergen, Inc. Compositions and methods for reestablishing gene transcription through inhibition of DNA methylation and histone deacetylase
WO2006105979A1 (en) * 2005-04-07 2006-10-12 Nycomed Gmbh Sulfonylpyrroles as histone deacetylase inhibitors
DK1879573T3 (da) 2005-05-10 2013-02-25 Incyte Corp Modulatorer af indolamin 2,3-dioxygenase og fremgangsmåder til anvendelse deraf
WO2007017065A2 (en) * 2005-07-27 2007-02-15 Oncomethylome Sciences Sa Angiogenesis inhibition based upon icam 1 or junb expression levels
US20110300142A1 (en) 2007-05-25 2011-12-08 Salford Leif G Use of zeburaline for the treatment of autoimmune diseases or immune rejection of transplants

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US20150182592A1 (en) 2015-07-02
EP2654758A1 (en) 2013-10-30
EP2654758A4 (en) 2014-05-07
CA2822745A1 (en) 2012-06-28
EP2654758B1 (en) 2017-04-19
US20180028621A1 (en) 2018-02-01
JP2014500312A (ja) 2014-01-09
WO2012087234A1 (en) 2012-06-28
ES2638818T3 (es) 2017-10-24
US9839674B2 (en) 2017-12-12
DK2654758T3 (en) 2017-07-10
PL2654758T3 (pl) 2017-10-31
EP3238726A2 (en) 2017-11-01
US20130309198A1 (en) 2013-11-21
EP3238726A3 (en) 2018-01-10

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