CA2822745A1 - A composition comprising at least two compounds which induces indolamine 2,3-dioxygenase (ido), for the treatment of an autoimmune disorder or suffering from immune rejection of organs - Google Patents
A composition comprising at least two compounds which induces indolamine 2,3-dioxygenase (ido), for the treatment of an autoimmune disorder or suffering from immune rejection of organs Download PDFInfo
- Publication number
- CA2822745A1 CA2822745A1 CA2822745A CA2822745A CA2822745A1 CA 2822745 A1 CA2822745 A1 CA 2822745A1 CA 2822745 A CA2822745 A CA 2822745A CA 2822745 A CA2822745 A CA 2822745A CA 2822745 A1 CA2822745 A1 CA 2822745A1
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- Prior art keywords
- ido
- autoimmune
- syndrome
- cells
- disease
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- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- A61P5/50—Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/06—Antianaemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- Gastroenterology & Hepatology (AREA)
- Endocrinology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Diabetes (AREA)
- Reproductive Health (AREA)
- Neurology (AREA)
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- Biomedical Technology (AREA)
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- Hematology (AREA)
- Molecular Biology (AREA)
- Obesity (AREA)
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- Rheumatology (AREA)
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- Physical Education & Sports Medicine (AREA)
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- Psychiatry (AREA)
- Pregnancy & Childbirth (AREA)
- Vascular Medicine (AREA)
- Pain & Pain Management (AREA)
- Hospice & Palliative Care (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE1051356-2 | 2010-12-22 | ||
| SE1051356 | 2010-12-22 | ||
| PCT/SE2011/051544 WO2012087234A1 (en) | 2010-12-22 | 2011-12-20 | A composition comprising at least to compounds which induces indolamine 2,3-dioxygenase (ido), for the treatment of an autoimmune disorder or suffering from immune rejection of organs |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2822745A1 true CA2822745A1 (en) | 2012-06-28 |
Family
ID=46314247
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2822745A Abandoned CA2822745A1 (en) | 2010-12-22 | 2011-12-20 | A composition comprising at least two compounds which induces indolamine 2,3-dioxygenase (ido), for the treatment of an autoimmune disorder or suffering from immune rejection of organs |
Country Status (8)
| Country | Link |
|---|---|
| US (3) | US20130309198A1 (enExample) |
| EP (2) | EP3238726A3 (enExample) |
| JP (1) | JP6063392B2 (enExample) |
| CA (1) | CA2822745A1 (enExample) |
| DK (1) | DK2654758T3 (enExample) |
| ES (1) | ES2638818T3 (enExample) |
| PL (1) | PL2654758T3 (enExample) |
| WO (1) | WO2012087234A1 (enExample) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EA029126B1 (ru) * | 2013-07-01 | 2018-02-28 | Бристол-Майерс Сквибб Компани | Ингибиторы ido |
| GB201504701D0 (en) * | 2015-03-19 | 2015-05-06 | Idogen Ab | Novel treatment method |
| CN104873731A (zh) * | 2015-05-22 | 2015-09-02 | 宫兆妮 | 用于狼疮肾炎的中药 |
| US20190201431A1 (en) * | 2016-08-26 | 2019-07-04 | Idogen Ab | Ex vivo methods of inducing ido expression in antigen presenting cells using a compound selected from the group consisting of azacytidine, and decitabine |
| WO2019126697A1 (en) * | 2017-12-21 | 2019-06-27 | Blumberg Richard S | Oxazole containing compounds as activators of ido1 and ahr |
| US11712425B2 (en) | 2018-03-14 | 2023-08-01 | Albert Einstein College Of Medicine | Immunoregulatory role of 3-OH-kynurenamine and uses thereof |
| JP2023512072A (ja) * | 2020-01-30 | 2023-03-23 | モデルナティエックス インコーポレイテッド | 代謝リプログラミングポリペプチドをコードするｍＲＮＡ及びその使用 |
| WO2024033896A1 (en) * | 2022-08-12 | 2024-02-15 | Biorchestra Co., Ltd. | Oligonucleotides targeting indoleamine 2,3-dioxygenase and uses thereof |
| US20240238384A1 (en) * | 2023-01-17 | 2024-07-18 | Regeneron Pharmaceuticals, Inc. | Treatment Of B27-Negative Uveitis With Inositol Polyphosphate Multikinase (IPMK) Therapeutic Agents Or Indoleamine 2,3-dioxygenase 2 (IDO2) Agonists |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6518012B1 (en) * | 1999-04-02 | 2003-02-11 | Health Research, Inc. | Method for regulating the expression of MHC antigens and CD40 by inhibitors of histone deacetylation |
| US6613753B2 (en) * | 2001-02-21 | 2003-09-02 | Supergen, Inc. | Restore cancer-suppressing functions to neoplastic cells through DNA hypomethylation |
| US6905669B2 (en) * | 2001-04-24 | 2005-06-14 | Supergen, Inc. | Compositions and methods for reestablishing gene transcription through inhibition of DNA methylation and histone deacetylase |
| JP5054671B2 (ja) | 2005-04-07 | 2012-10-24 | フォーエスシー アクチエンゲゼルシャフト | ヒストンデアセチラーゼインヒビターとしてのスルホニルピロール |
| AU2006244068B9 (en) | 2005-05-10 | 2012-10-25 | Incyte Holdings Corporation | Modulators of indoleamine 2,3-dioxygenase and methods of using the same |
| WO2007017065A2 (en) * | 2005-07-27 | 2007-02-15 | Oncomethylome Sciences Sa | Angiogenesis inhibition based upon icam 1 or junb expression levels |
| EP2164500B1 (en) | 2007-05-25 | 2013-12-04 | Idogen AB | The use of zeburaline for the treatment of autoimmune diseases or immune rejection of transplants |
-
2011
- 2011-12-20 EP EP17166929.4A patent/EP3238726A3/en not_active Withdrawn
- 2011-12-20 PL PL11850142T patent/PL2654758T3/pl unknown
- 2011-12-20 CA CA2822745A patent/CA2822745A1/en not_active Abandoned
- 2011-12-20 DK DK11850142.8T patent/DK2654758T3/en active
- 2011-12-20 EP EP11850142.8A patent/EP2654758B1/en not_active Not-in-force
- 2011-12-20 US US13/997,356 patent/US20130309198A1/en not_active Abandoned
- 2011-12-20 ES ES11850142.8T patent/ES2638818T3/es active Active
- 2011-12-20 JP JP2013546073A patent/JP6063392B2/ja not_active Expired - Fee Related
- 2011-12-20 WO PCT/SE2011/051544 patent/WO2012087234A1/en not_active Ceased
-
2014
- 2014-11-25 US US14/553,098 patent/US9839674B2/en not_active Expired - Fee Related
-
2017
- 2017-10-16 US US15/785,075 patent/US20180028621A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| DK2654758T3 (en) | 2017-07-10 |
| ES2638818T3 (es) | 2017-10-24 |
| US9839674B2 (en) | 2017-12-12 |
| JP2014500312A (ja) | 2014-01-09 |
| EP3238726A3 (en) | 2018-01-10 |
| US20130309198A1 (en) | 2013-11-21 |
| PL2654758T3 (pl) | 2017-10-31 |
| WO2012087234A1 (en) | 2012-06-28 |
| EP2654758B1 (en) | 2017-04-19 |
| EP3238726A2 (en) | 2017-11-01 |
| US20150182592A1 (en) | 2015-07-02 |
| US20180028621A1 (en) | 2018-02-01 |
| JP6063392B2 (ja) | 2017-01-18 |
| EP2654758A1 (en) | 2013-10-30 |
| EP2654758A4 (en) | 2014-05-07 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request |
Effective date: 20161215 |
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| FZDE | Discontinued |
Effective date: 20200211 |