JP6031122B2 - 抗微生物療法のための三環式ホウ素化合物 - Google Patents

抗微生物療法のための三環式ホウ素化合物 Download PDF

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Publication number
JP6031122B2
JP6031122B2 JP2014548243A JP2014548243A JP6031122B2 JP 6031122 B2 JP6031122 B2 JP 6031122B2 JP 2014548243 A JP2014548243 A JP 2014548243A JP 2014548243 A JP2014548243 A JP 2014548243A JP 6031122 B2 JP6031122 B2 JP 6031122B2
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compounds
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JP2015502974A (ja
JP2015502974A5 (cg-RX-API-DMAC7.html
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フェドロビッチ ゴルデエフ ミハイル
フェドロビッチ ゴルデエフ ミハイル
リウ ジンキアン
リウ ジンキアン
ユアン ズヘンギュ
ユアン ズヘンギュ
ワング ジングハイ
ワング ジングハイ
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic Table
    • C07F5/02—Boron compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Communicable Diseases (AREA)
  • Ophthalmology & Optometry (AREA)
  • Oncology (AREA)
  • Pulmonology (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
JP2014548243A 2011-12-22 2012-12-20 抗微生物療法のための三環式ホウ素化合物 Expired - Fee Related JP6031122B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161579271P 2011-12-22 2011-12-22
US61/579,271 2011-12-22
PCT/IB2012/002880 WO2013093615A1 (en) 2011-12-22 2012-12-20 Tricyclic boron compounds for antimicrobial therapy

Publications (3)

Publication Number Publication Date
JP2015502974A JP2015502974A (ja) 2015-01-29
JP2015502974A5 JP2015502974A5 (cg-RX-API-DMAC7.html) 2016-02-12
JP6031122B2 true JP6031122B2 (ja) 2016-11-24

Family

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Family Applications (1)

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JP2014548243A Expired - Fee Related JP6031122B2 (ja) 2011-12-22 2012-12-20 抗微生物療法のための三環式ホウ素化合物

Country Status (7)

Country Link
US (1) US8530452B2 (cg-RX-API-DMAC7.html)
EP (1) EP2793901A1 (cg-RX-API-DMAC7.html)
JP (1) JP6031122B2 (cg-RX-API-DMAC7.html)
KR (1) KR20140114380A (cg-RX-API-DMAC7.html)
CN (1) CN104136032B (cg-RX-API-DMAC7.html)
CA (1) CA2858799A1 (cg-RX-API-DMAC7.html)
WO (1) WO2013093615A1 (cg-RX-API-DMAC7.html)

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* Cited by examiner, † Cited by third party
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US9585396B2 (en) 2013-01-30 2017-03-07 Agrofresh Inc. Volatile applications against pathogens
US11039617B2 (en) 2013-01-30 2021-06-22 Agrofresh Inc. Large scale methods of uniformly coating packaging surfaces with a volatile antimicrobial to preserve food freshness
MX356059B (es) * 2013-01-30 2018-05-11 Dow Agrosciences Llc Uso de benzoxaboroles como agentes antimicrobianos volatiles en carnes, plantas, o partes de plantas.
US10070649B2 (en) 2013-01-30 2018-09-11 Agrofresh Inc. Volatile applications against pathogens
KR101636431B1 (ko) * 2013-07-30 2016-07-05 동아에스티 주식회사 트리사이클릭 벤즈옥사보롤 화합물, 이의 제조방법 및 용도
DK3030519T3 (da) * 2013-08-09 2022-01-31 Glaxosmithkline Ip No 2 Ltd Tricykliske benzoxaborol-forbindelser og anvendelser deraf
EA038093B1 (ru) * 2013-12-20 2021-07-05 Глаксосмитклайн Интеллекчуал Проперти (№2) Лимитед Способ лечения заболевания, вызванного инфекцией комплекса mycobacterium tuberculosis, с использованием (s)-(3-хлор-7,8-дигидро-2h-1,6,9-триокса-9a-борабензо[cd]азулен-2-ил)метанамина или его фармацевтически приемлемой соли
TW201625649A (zh) 2014-07-01 2016-07-16 第一三共股份有限公司 作爲抗菌劑的三環化合物
CN104177226A (zh) * 2014-07-31 2014-12-03 河北国蓬化工有限公司 一种聚醚用催化剂的制备方法
MA41495A (fr) * 2015-02-12 2017-12-19 Anacor Pharmaceuticals Inc Composés benzoxaborole et leurs utilisations
WO2017155879A1 (en) 2016-03-07 2017-09-14 Agrofresh Inc. Synergistic methods of using benzoxaborole compounds and preservative gases as an antimicrobial for crops
KR101925338B1 (ko) 2016-12-22 2018-12-05 엘에스산전 주식회사 전력기기 진단 장치
EP3850029A1 (en) 2019-08-09 2021-07-21 Safas Saf Plastik Sanayi Ve Ticaret Anonim Sirketi Boron-modified flexible polyurethane foam for hygiene and a method of production therefor
EP4384527A4 (en) * 2022-06-23 2025-09-03 Micurx Pharmaceuticals Inc PRODRUGS OF BORON COMPOUNDS AND THEIR USE IN THE TREATMENT OF BACTERIAL INFECTIONS
AU2023287202A1 (en) 2022-06-23 2024-06-06 Shanghai Micurx Pharmaceutical Co., Ltd. Methods and uses of boron compounds in the treatment of nontuberculous mycobacterium infections and pharmaceutical compositions for treatment of same
WO2025140370A1 (zh) * 2023-12-27 2025-07-03 上海盟科药业股份有限公司 硼化合物前药的盐型、晶型及其药物组合物和用途

Family Cites Families (16)

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US4235871A (en) 1978-02-24 1980-11-25 Papahadjopoulos Demetrios P Method of encapsulating biologically active materials in lipid vesicles
US4501728A (en) 1983-01-06 1985-02-26 Technology Unlimited, Inc. Masking of liposomes from RES recognition
US5023252A (en) 1985-12-04 1991-06-11 Conrex Pharmaceutical Corporation Transdermal and trans-membrane delivery of drugs
US4837028A (en) 1986-12-24 1989-06-06 Liposome Technology, Inc. Liposomes with enhanced circulation time
US5011472A (en) 1988-09-06 1991-04-30 Brown University Research Foundation Implantable delivery system for biological factors
CA2529792A1 (en) 2003-06-16 2005-02-17 Anacor Pharmaceuticals, Inc. Hydrolytically-resistant boron-containing therapeutics and methods of use
DK1988779T5 (en) * 2006-02-16 2016-10-10 Anacor Pharmaceuticals Inc SMALL boron MOLECULES AS ANTI-INFLAMMATORY AGENTS
BRPI0711155A2 (pt) 2006-05-02 2011-08-23 Anacor Pharmaceuticals Inc terapêuticos contendo boro resistentes hidroliticamente e métodos de uso
US20070286822A1 (en) * 2006-06-12 2007-12-13 Anacor Pharmaceuticals Inc. Compounds for the Treatment of Periodontal Disease
JO3396B1 (ar) * 2007-06-20 2019-10-20 Anacor Pharmaceuticals Inc جزيئات صغيرة تحتوي على البورون
US20100256092A1 (en) 2008-05-12 2010-10-07 Anacor Pharmaceuticals, Inc. Boron-containing small molecules
US20110259250A1 (en) 2008-08-21 2011-10-27 Mcknight James T Systems And Methods For Converting Biomass In The Field To A Combustible Fluid For Direct Replacement Or Supplement To Liquid Fossil Fuels
KR20110111407A (ko) * 2008-12-17 2011-10-11 아나코르 파마슈티칼스 인코포레이티드 (ｓ)-３-아미노메틸-７-(３-히드록시-프로폭시)-３ｈ-벤조〔ｃ〕〔１,２〕옥사보롤-１-올의 다형태
EP2458995A1 (en) 2009-07-28 2012-06-06 Anacor Pharmaceuticals, Inc. Trisubstituted boron-containing molecules
MX352607B (es) 2010-04-07 2017-11-30 Glaxosmithkline Llc Star Proceso para la preparacion de benzoxaboroles.
BR112013005426B1 (pt) 2010-09-07 2021-08-24 Anacor Pharmaceuticals, Inc Composto, composição, combinação, e, formulação farmacêutica

Also Published As

Publication number Publication date
EP2793901A1 (en) 2014-10-29
KR20140114380A (ko) 2014-09-26
WO2013093615A1 (en) 2013-06-27
CA2858799A1 (en) 2013-06-27
CN104136032A (zh) 2014-11-05
JP2015502974A (ja) 2015-01-29
CN104136032B (zh) 2018-11-13
US8530452B2 (en) 2013-09-10
US20130165411A1 (en) 2013-06-27

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