JP6027267B2 - Comt阻害剤 - Google Patents
Comt阻害剤 Download PDFInfo
- Publication number
- JP6027267B2 JP6027267B2 JP2015550063A JP2015550063A JP6027267B2 JP 6027267 B2 JP6027267 B2 JP 6027267B2 JP 2015550063 A JP2015550063 A JP 2015550063A JP 2015550063 A JP2015550063 A JP 2015550063A JP 6027267 B2 JP6027267 B2 JP 6027267B2
- Authority
- JP
- Japan
- Prior art keywords
- hydroxy
- quinazolin
- phenyl
- methyl
- hydroxyquinazolin
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- HEFQEZQZUIUGMB-UHFFFAOYSA-N CC(C)(C)C(OCOc1cc(Br)cc2c1N=CN(COC(OC(C)(C)C)=O)C2=O)=O Chemical compound CC(C)(C)C(OCOc1cc(Br)cc2c1N=CN(COC(OC(C)(C)C)=O)C2=O)=O HEFQEZQZUIUGMB-UHFFFAOYSA-N 0.000 description 1
- UJTNYIAUNLZKAC-OMCISZLKSA-N CN(C)/C=N/c(c(Br)c(C(F)(F)F)cc1)c1OC Chemical compound CN(C)/C=N/c(c(Br)c(C(F)(F)F)cc1)c1OC UJTNYIAUNLZKAC-OMCISZLKSA-N 0.000 description 1
- ARZLMIOXJVODCM-REZTVBANSA-N CN(C)/C=N/c(c(C#N)c(C(F)(F)F)cc1)c1OC Chemical compound CN(C)/C=N/c(c(C#N)c(C(F)(F)F)cc1)c1OC ARZLMIOXJVODCM-REZTVBANSA-N 0.000 description 1
- BDVYHOFMSTWJRC-VIZOYTHASA-N CN(C)/C=N/c1cc(C(F)(F)F)ccc1OC Chemical compound CN(C)/C=N/c1cc(C(F)(F)F)ccc1OC BDVYHOFMSTWJRC-VIZOYTHASA-N 0.000 description 1
- MYWWFKHSVPLXMT-UHFFFAOYSA-N COc(ccc(C(F)(F)F)c1C#N)c1N Chemical compound COc(ccc(C(F)(F)F)c1C#N)c1N MYWWFKHSVPLXMT-UHFFFAOYSA-N 0.000 description 1
- IVHVBVMREUQUCX-UHFFFAOYSA-N COc1cc(Br)cc2c1N=CNC2=O Chemical compound COc1cc(Br)cc2c1N=CNC2=O IVHVBVMREUQUCX-UHFFFAOYSA-N 0.000 description 1
- HRCRRMZTRXLVAE-UHFFFAOYSA-N COc1ccc(C(F)(F)F)c(C(N)=O)c1N Chemical compound COc1ccc(C(F)(F)F)c(C(N)=O)c1N HRCRRMZTRXLVAE-UHFFFAOYSA-N 0.000 description 1
- RKUSRLUGUVDNKP-UHFFFAOYSA-N COc1ccc(C(F)(F)F)cc1N Chemical compound COc1ccc(C(F)(F)F)cc1N RKUSRLUGUVDNKP-UHFFFAOYSA-N 0.000 description 1
- VZOKMTFBSRRQSG-UHFFFAOYSA-N Oc1ccc(C(F)(F)F)c2c1N=CNC2=O Chemical compound Oc1ccc(C(F)(F)F)c2c1N=CNC2=O VZOKMTFBSRRQSG-UHFFFAOYSA-N 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
- C07D239/72—Quinazolines; Hydrogenated quinazolines
- C07D239/86—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in position 4
- C07D239/88—Oxygen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/517—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Psychiatry (AREA)
- Psychology (AREA)
- Hospice & Palliative Care (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Epidemiology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP12199491.7 | 2012-12-27 | ||
EP12199491 | 2012-12-27 | ||
PCT/EP2013/077885 WO2014102233A1 (en) | 2012-12-27 | 2013-12-23 | Comt inhibitors |
Publications (2)
Publication Number | Publication Date |
---|---|
JP2016507507A JP2016507507A (ja) | 2016-03-10 |
JP6027267B2 true JP6027267B2 (ja) | 2016-11-16 |
Family
ID=47519943
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2015550063A Expired - Fee Related JP6027267B2 (ja) | 2012-12-27 | 2013-12-23 | Comt阻害剤 |
Country Status (11)
Country | Link |
---|---|
US (1) | US9656971B2 (es) |
EP (1) | EP2938600B1 (es) |
JP (1) | JP6027267B2 (es) |
KR (1) | KR101685862B1 (es) |
CN (1) | CN104903300B (es) |
BR (1) | BR112015013989A2 (es) |
CA (1) | CA2886139A1 (es) |
HK (1) | HK1208466A1 (es) |
MX (1) | MX2015006437A (es) |
RU (1) | RU2642779C2 (es) |
WO (1) | WO2014102233A1 (es) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN107922403A (zh) | 2015-06-26 | 2018-04-17 | 武田药品工业株式会社 | 作为胆碱能毒蕈碱m1受体的调节剂的2,3‑二氢‑4h‑1,3‑苯并噁嗪‑4‑酮衍生物 |
CN105111193B (zh) * | 2015-09-12 | 2018-03-06 | 山东罗欣药业集团股份有限公司 | 一种拉帕替尼的制备方法 |
EP3366679B1 (en) | 2015-10-20 | 2021-03-24 | Takeda Pharmaceutical Company Limited | Heterocyclic compound |
CN106083850B (zh) * | 2016-07-13 | 2018-01-02 | 河南大学 | 一类嘧啶并萘酰亚胺衍生物及其制备方法和应用 |
US11560372B2 (en) | 2017-04-18 | 2023-01-24 | Takeda Pharmaceutical Company Limited | Heterocyclic compounds useful as modulators of acetylcholine receptors |
CN114269432B (zh) * | 2019-05-31 | 2024-05-07 | 奇斯药制品公司 | 作为p2x3抑制剂的氨基喹唑啉衍生物 |
WO2024104818A1 (en) | 2022-11-16 | 2024-05-23 | Basf Se | Substituted benzodiazepines as fungicides |
WO2024104815A1 (en) | 2022-11-16 | 2024-05-23 | Basf Se | Substituted benzodiazepines as fungicides |
WO2024104822A1 (en) | 2022-11-16 | 2024-05-23 | Basf Se | Substituted tetrahydrobenzodiazepine as fungicides |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2500952C (en) * | 2002-10-04 | 2011-04-26 | Prana Biotechnology Limited | Neurologically-active compounds |
MXPA06005894A (es) * | 2003-12-19 | 2006-06-27 | Hoffmann La Roche | Inhibidores de comt. |
JP4102939B2 (ja) * | 2004-02-13 | 2008-06-18 | 萬有製薬株式会社 | 縮環4−オキソ−ピリミジン誘導体 |
CA2656825C (en) * | 2006-06-22 | 2013-12-10 | Prana Biotechnology Limited | Method of treatment and agents useful for same |
WO2010071944A1 (en) | 2008-12-24 | 2010-07-01 | Prana Biotechnology Limited | Quinazolinone compounds |
BR112012021652A2 (pt) * | 2010-03-04 | 2016-06-21 | Merck Sharp & Dohme | composto, uso do mesmo, e, composição farmacêutica |
CN102933079B (zh) * | 2010-03-04 | 2016-02-17 | 默沙东公司 | 儿茶酚-o-甲基转移酶抑制剂及其在治疗精神障碍中的用途 |
MX336711B (es) * | 2010-03-04 | 2016-01-28 | Merck Sharp & Dohme | Inhibidores de catecol o-metil transferasa y su uso en el tratamiento de transtornos psicoticos. |
-
2013
- 2013-12-23 MX MX2015006437A patent/MX2015006437A/es unknown
- 2013-12-23 BR BR112015013989A patent/BR112015013989A2/pt not_active Application Discontinuation
- 2013-12-23 RU RU2015128025A patent/RU2642779C2/ru not_active IP Right Cessation
- 2013-12-23 CA CA2886139A patent/CA2886139A1/en not_active Abandoned
- 2013-12-23 CN CN201380068084.6A patent/CN104903300B/zh not_active Expired - Fee Related
- 2013-12-23 EP EP13820775.8A patent/EP2938600B1/en not_active Not-in-force
- 2013-12-23 WO PCT/EP2013/077885 patent/WO2014102233A1/en active Application Filing
- 2013-12-23 JP JP2015550063A patent/JP6027267B2/ja not_active Expired - Fee Related
- 2013-12-23 KR KR1020157017134A patent/KR101685862B1/ko active IP Right Grant
-
2015
- 2015-06-26 US US14/752,177 patent/US9656971B2/en not_active Expired - Fee Related
- 2015-09-21 HK HK15109263.4A patent/HK1208466A1/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
BR112015013989A2 (pt) | 2017-07-11 |
WO2014102233A1 (en) | 2014-07-03 |
CN104903300A (zh) | 2015-09-09 |
MX2015006437A (es) | 2015-08-14 |
RU2015128025A (ru) | 2017-01-31 |
EP2938600A1 (en) | 2015-11-04 |
US20160002177A1 (en) | 2016-01-07 |
RU2642779C2 (ru) | 2018-01-26 |
KR20150088884A (ko) | 2015-08-03 |
JP2016507507A (ja) | 2016-03-10 |
US9656971B2 (en) | 2017-05-23 |
HK1208466A1 (en) | 2016-03-04 |
EP2938600B1 (en) | 2017-01-25 |
CN104903300B (zh) | 2018-04-17 |
CA2886139A1 (en) | 2014-07-03 |
KR101685862B1 (ko) | 2016-12-20 |
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