JP6019015B2 - 6−シクロヘキシル−1−ヒドロキシ−4−メチル−2(1h)−ピリドンを使用する血液悪性疾患の治療方法 - Google Patents
6−シクロヘキシル−1−ヒドロキシ−4−メチル−2(1h)−ピリドンを使用する血液悪性疾患の治療方法 Download PDFInfo
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- JP6019015B2 JP6019015B2 JP2013513289A JP2013513289A JP6019015B2 JP 6019015 B2 JP6019015 B2 JP 6019015B2 JP 2013513289 A JP2013513289 A JP 2013513289A JP 2013513289 A JP2013513289 A JP 2013513289A JP 6019015 B2 JP6019015 B2 JP 6019015B2
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- resistant
- leukemia
- pharmaceutical composition
- drug
- methyl
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- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
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- SCKYRAXSEDYPSA-UHFFFAOYSA-N CC(C=C(C1CCCCC1)N1O)=CC1=O Chemical compound CC(C=C(C1CCCCC1)N1O)=CC1=O SCKYRAXSEDYPSA-UHFFFAOYSA-N 0.000 description 1
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4418—Non condensed pyridines; Hydrogenated derivatives thereof having a carbocyclic group directly attached to the heterocyclic ring, e.g. cyproheptadine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Oncology (AREA)
- Hematology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US35043810P | 2010-06-01 | 2010-06-01 | |
| US61/350,438 | 2010-06-01 | ||
| PCT/US2011/038702 WO2011153199A1 (en) | 2010-06-01 | 2011-06-01 | Methods of treating hematologic malignancies using 6-cyclohexyl-1-hydroxy-4-methyl-2(1h)-pyridone |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2013528620A JP2013528620A (ja) | 2013-07-11 |
| JP2013528620A5 JP2013528620A5 (enExample) | 2014-07-17 |
| JP6019015B2 true JP6019015B2 (ja) | 2016-11-02 |
Family
ID=44534598
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013513289A Expired - Fee Related JP6019015B2 (ja) | 2010-06-01 | 2011-06-01 | 6−シクロヘキシル−1−ヒドロキシ−4−メチル−2(1h)−ピリドンを使用する血液悪性疾患の治療方法 |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US20130178503A1 (enExample) |
| EP (1) | EP2585063A1 (enExample) |
| JP (1) | JP6019015B2 (enExample) |
| CN (1) | CN103153309A (enExample) |
| AU (1) | AU2011261501B2 (enExample) |
| CA (1) | CA2801003A1 (enExample) |
| MX (1) | MX342465B (enExample) |
| WO (1) | WO2011153199A1 (enExample) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP5844354B2 (ja) | 2010-06-01 | 2016-01-13 | ビオトヘルイク, インコーポレイテッド | ヒドロキシピリドン誘導体、その医薬組成物、及び増殖性疾患治療のためのその治療的使用 |
| WO2015195474A1 (en) | 2014-06-18 | 2015-12-23 | Biotheryx, Inc. | Hydroxypyridone derivatives, pharmaceutical compositions thereof, and their therapeutic use for treating inflammatory, neurodegenerative, or immune-mediated diseases |
| CN116077522B (zh) * | 2023-03-09 | 2024-01-26 | 青岛市中心医院 | 一种用于治疗白血病的治疗制剂 |
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| AU8769291A (en) * | 1990-09-17 | 1992-04-15 | Children's Medical Center Corporation | Deoxyhypusyl hydroxylase inhibitors |
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| US5591767A (en) | 1993-01-25 | 1997-01-07 | Pharmetrix Corporation | Liquid reservoir transdermal patch for the administration of ketorolac |
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| JP3170176B2 (ja) * | 1995-05-17 | 2001-05-28 | 大塚製薬株式会社 | 薬剤耐性獲得癌細胞の検出方法 |
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| TW345603B (en) | 1996-05-29 | 1998-11-21 | Gmundner Fertigteile Gmbh | A noise control device for tracks |
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| US6350458B1 (en) | 1998-02-10 | 2002-02-26 | Generex Pharmaceuticals Incorporated | Mixed micellar drug deliver system and method of preparation |
| US6613358B2 (en) | 1998-03-18 | 2003-09-02 | Theodore W. Randolph | Sustained-release composition including amorphous polymer |
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| KR19990085365A (ko) | 1998-05-16 | 1999-12-06 | 허영섭 | 지속적으로 약물 조절방출이 가능한 생분해성 고분자 미립구 및그 제조방법 |
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| WO2010048712A1 (en) * | 2008-10-31 | 2010-05-06 | University Health Network | Ciclopirox and cytarabine for the treatment of leukemic disorders |
-
2011
- 2011-06-01 US US13/701,486 patent/US20130178503A1/en not_active Abandoned
- 2011-06-01 AU AU2011261501A patent/AU2011261501B2/en not_active Ceased
- 2011-06-01 MX MX2012013878A patent/MX342465B/es active IP Right Grant
- 2011-06-01 JP JP2013513289A patent/JP6019015B2/ja not_active Expired - Fee Related
- 2011-06-01 CA CA2801003A patent/CA2801003A1/en not_active Abandoned
- 2011-06-01 CN CN2011800379525A patent/CN103153309A/zh active Pending
- 2011-06-01 EP EP11726556.1A patent/EP2585063A1/en not_active Withdrawn
- 2011-06-01 WO PCT/US2011/038702 patent/WO2011153199A1/en not_active Ceased
-
2015
- 2015-08-21 US US14/832,740 patent/US20150342942A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| US20130178503A1 (en) | 2013-07-11 |
| US20150342942A1 (en) | 2015-12-03 |
| MX2012013878A (es) | 2013-06-28 |
| MX342465B (es) | 2016-09-30 |
| CA2801003A1 (en) | 2011-12-08 |
| CN103153309A (zh) | 2013-06-12 |
| AU2011261501B2 (en) | 2016-01-21 |
| AU2011261501A1 (en) | 2013-01-10 |
| EP2585063A1 (en) | 2013-05-01 |
| JP2013528620A (ja) | 2013-07-11 |
| WO2011153199A1 (en) | 2011-12-08 |
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