JP6006231B2 - 拡散バリアを用いたレーザードップラー電気泳動法 - Google Patents

拡散バリアを用いたレーザードップラー電気泳動法 Download PDF

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JP6006231B2
JP6006231B2 JP2013544856A JP2013544856A JP6006231B2 JP 6006231 B2 JP6006231 B2 JP 6006231B2 JP 2013544856 A JP2013544856 A JP 2013544856A JP 2013544856 A JP2013544856 A JP 2013544856A JP 6006231 B2 JP6006231 B2 JP 6006231B2
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sample
electrode
dispersant
container
diffusion barrier
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JP2013546003A (ja
JP2013546003A5 (enExample
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ジェイソン セシル ウィリアム コルベット
ジェイソン セシル ウィリアム コルベット
マルコム コナー
マルコム コナー
ケビン マティソン
ケビン マティソン
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マルバーン インストゥルメンツ リミテッド
マルバーン インストゥルメンツ リミテッド
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/416—Systems
    • G01N27/447—Systems using electrophoresis
    • G01N27/44704—Details; Accessories
    • G01N27/44717—Arrangements for investigating the separated zones, e.g. localising zones
    • G01N27/44721—Arrangements for investigating the separated zones, e.g. localising zones by optical means
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/416—Systems
    • G01N27/447—Systems using electrophoresis
    • G01N27/44704—Details; Accessories
    • G01N27/44717—Arrangements for investigating the separated zones, e.g. localising zones
    • G01N27/44739—Collecting the separated zones, e.g. blotting to a membrane or punching of gel spots

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Chemical & Material Sciences (AREA)
  • Biochemistry (AREA)
  • Electrochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Optical Measuring Cells (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
JP2013544856A 2010-12-17 2011-12-16 拡散バリアを用いたレーザードップラー電気泳動法 Active JP6006231B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US12/972,412 2010-12-17
US12/972,412 US8702942B2 (en) 2010-12-17 2010-12-17 Laser doppler electrophoresis using a diffusion barrier
PCT/US2011/065673 WO2012083272A1 (en) 2010-12-17 2011-12-16 Laser doppler electrophoresis using a diffusion barrier

Related Child Applications (1)

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JP2016174957A Division JP6453285B2 (ja) 2010-12-17 2016-09-07 拡散バリアを用いたレーザードップラー電気泳動法

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JP2013546003A JP2013546003A (ja) 2013-12-26
JP2013546003A5 JP2013546003A5 (enExample) 2015-01-29
JP6006231B2 true JP6006231B2 (ja) 2016-10-12

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JP2013544856A Active JP6006231B2 (ja) 2010-12-17 2011-12-16 拡散バリアを用いたレーザードップラー電気泳動法
JP2016174957A Active JP6453285B2 (ja) 2010-12-17 2016-09-07 拡散バリアを用いたレーザードップラー電気泳動法

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US (1) US8702942B2 (enExample)
EP (1) EP2652490B1 (enExample)
JP (2) JP6006231B2 (enExample)
CN (1) CN103339500B (enExample)
WO (1) WO2012083272A1 (enExample)

Families Citing this family (9)

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Publication number Priority date Publication date Assignee Title
US10648945B2 (en) 2010-12-17 2020-05-12 Malvern Panalytical Limited Laser doppler electrophoresis using a diffusion barrier
WO2016127104A2 (en) 2015-02-06 2016-08-11 University Of Maryland, Baltimore Tetra-specific, octameric binding agents and antibodies against clostridium difficile toxin a and toxin b for treatment of c. difficile infection
DE102015003019A1 (de) 2015-03-06 2016-09-08 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Verfahren und Vorrichtung zur optischen Detektion einer Bewegung in einer biologischen Probe mit räumlicher Ausdehnung
US10369582B2 (en) 2015-04-30 2019-08-06 Emissol Llc System and method for spray visualization
US11130686B2 (en) 2017-01-10 2021-09-28 Vermeer Manufacturing Company Systems and methods for dosing slurries to remove suspended solids
JPWO2020230219A1 (enExample) 2019-05-10 2020-11-19
WO2021070385A1 (ja) 2019-10-11 2021-04-15 アイポア株式会社 粒子の識別を行うためのセンサ、測定器、コンピュータ装置、およびシステム
US20220218622A1 (en) 2020-10-14 2022-07-14 George Mason Research Foundation, Inc. Ionizable lipids and methods of manufacture and use thereof
JPWO2023149526A1 (enExample) 2022-02-02 2023-08-10

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1583800A (enExample) * 1967-05-29 1969-10-27
US3766048A (en) * 1972-11-24 1973-10-16 Univ Illinois Analysis of polymer mixtures in solution utilizing electrophoretic light scattering apparatus
US4101220A (en) * 1977-03-31 1978-07-18 General Electric Company Laser Doppler spectroscopy with smoothened spectra line shapes
DE2852978C3 (de) * 1978-12-07 1981-06-04 Raimund Dr. 4005 Meerbusch Kaufmann Vorrichtung zur spektroskopischen Bestimmung der Geschwindigkeit von in einer Flüssigkeit bewegten Teilchen
JPS574546A (en) * 1980-06-10 1982-01-11 Shimadzu Corp Measuring apparatus for electrophoresis of suspended particle
ATE249036T1 (de) * 1993-06-07 2003-09-15 Colloidal Dynamics Pty Ltd Messung der teilchengrösse und -ladung in mehrkomponenten-kolloiden
CN1192097C (zh) * 1995-03-10 2005-03-09 梅索磅秤技术有限公司 多阵列、多特异性的电化学发光检验
JPH09292358A (ja) * 1996-02-29 1997-11-11 Horiba Ltd 光走査型二次元濃度分布測定装置を用いたゼータ電位計測方法
US6406602B1 (en) 1998-12-23 2002-06-18 Genome Therapeutics Corporation Sample loading device for gel electrophoresis
JP2001264282A (ja) * 2000-03-16 2001-09-26 Kobe Steel Ltd 金属材表面のゼータ電位測定方法およびゼータ電位測定装置、金属材の表面特性の評価方法
GB2361772B (en) * 2000-04-29 2004-05-19 Malvern Instr Ltd Mobility and effects arising from surface charge
AU2001292884A1 (en) * 2000-09-20 2002-04-02 Molecular Reflections Microfabricated ultrasound array for use as resonant sensors
GB2368904A (en) 2000-11-10 2002-05-15 Zetatronics Ltd Obtaining informatiion about zeta potential, electrophoretic mobility and numbers of suspended particles
JP2002360237A (ja) * 2001-06-08 2002-12-17 Mitsubishi Chemicals Corp 試料収容容器
JP4334899B2 (ja) * 2003-02-25 2009-09-30 大塚電子株式会社 電気泳動速度測定装置
JP2006177732A (ja) * 2004-12-21 2006-07-06 Matsushita Electric Ind Co Ltd 生体物質回収装置および生体物質回収方法
JP2006226981A (ja) * 2005-02-18 2006-08-31 Microtec Nition:Kk 簡易型電気泳動式ゼータ電位計
JP2010101705A (ja) * 2008-10-22 2010-05-06 Horiba Ltd 粒子物性測定装置
US8441638B2 (en) * 2010-02-26 2013-05-14 Wyatt Technology Corporation Apparatus to measure particle mobility in solution with scattered and unscattered light
JP5363295B2 (ja) * 2009-09-01 2013-12-11 株式会社堀場製作所 ゼータ電位測定セル及びゼータ電位測定装置

Also Published As

Publication number Publication date
EP2652490A1 (en) 2013-10-23
JP2013546003A (ja) 2013-12-26
US20120152745A1 (en) 2012-06-21
JP2016200608A (ja) 2016-12-01
JP6453285B2 (ja) 2019-01-16
WO2012083272A1 (en) 2012-06-21
CN103339500B (zh) 2016-01-20
CN103339500A (zh) 2013-10-02
US8702942B2 (en) 2014-04-22
EP2652490B1 (en) 2018-03-21

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