JP5981141B2 - 多臓器不全症候群(mods)の予防および/または処置のためのインターロイキン−22の使用 - Google Patents

多臓器不全症候群(mods)の予防および/または処置のためのインターロイキン−22の使用 Download PDF

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Publication number
JP5981141B2
JP5981141B2 JP2011545498A JP2011545498A JP5981141B2 JP 5981141 B2 JP5981141 B2 JP 5981141B2 JP 2011545498 A JP2011545498 A JP 2011545498A JP 2011545498 A JP2011545498 A JP 2011545498A JP 5981141 B2 JP5981141 B2 JP 5981141B2
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pharmaceutical composition
multiple organ
subject
organ dysfunction
mods
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Japanese (ja)
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JP2012515165A (ja
JP2012515165A5 (enExample
Inventor
リャン ファン,ユウ
リャン ファン,ユウ
ファ ファン,ツィー
ファ ファン,ツィー
スン,チー
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Generon Shanghai Corp Ltd
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Generon Shanghai Corp Ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19Cytokines; Lymphokines; Interferons
    • A61K38/20Interleukins [IL]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19Cytokines; Lymphokines; Interferons
    • A61K38/20Interleukins [IL]
    • A61K38/2066IL-10
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Communicable Diseases (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Oncology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
JP2011545498A 2009-01-12 2010-01-11 多臓器不全症候群(mods)の予防および/または処置のためのインターロイキン−22の使用 Active JP5981141B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US14413409P 2009-01-12 2009-01-12
US61/144,134 2009-01-12
PCT/US2010/020673 WO2010081112A1 (en) 2009-01-12 2010-01-11 Prevention and/or treatment of multiple organ dysfunction syndrome with interleukin-22

Publications (3)

Publication Number Publication Date
JP2012515165A JP2012515165A (ja) 2012-07-05
JP2012515165A5 JP2012515165A5 (enExample) 2013-02-28
JP5981141B2 true JP5981141B2 (ja) 2016-08-31

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JP2011545498A Active JP5981141B2 (ja) 2009-01-12 2010-01-11 多臓器不全症候群(mods)の予防および/または処置のためのインターロイキン−22の使用

Country Status (7)

Country Link
US (1) US8956605B2 (enExample)
EP (1) EP2385841B1 (enExample)
JP (1) JP5981141B2 (enExample)
CN (1) CN102348463B (enExample)
AU (1) AU2010203446B2 (enExample)
CA (1) CA2748392C (enExample)
WO (1) WO2010081112A1 (enExample)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101361968B (zh) 2007-08-06 2011-08-03 健能隆医药技术(上海)有限公司 白介素-22在治疗脂肪肝中的应用
EA035645B1 (ru) 2013-03-15 2020-07-21 Дженентек, Инк. ПОЛИПЕПТИДЫ IL-22, ХИМЕРНЫЕ БЕЛКИ IL-22 Fc И ИХ ПРИМЕНЕНИЕ
CN104623637A (zh) 2013-11-07 2015-05-20 健能隆医药技术(上海)有限公司 Il-22二聚体在制备静脉注射药物中的应用
EP3442562B1 (en) 2016-04-15 2022-09-21 Evive Biotechnology (Shanghai) Ltd An il-22 dimer for use in treating necrotizing enterocolitis
CN112007146A (zh) * 2020-09-03 2020-12-01 上海市儿童医院 Il-22在治疗和/或预防脓毒症诱发的肝脏损伤的药物中的用途
US20240033232A1 (en) * 2021-03-10 2024-02-01 Wen Tan New use of (R)-B2-agonists in treatment of sepsis and acute respiratory distress syndrome

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030003545A1 (en) 1998-05-29 2003-01-02 Reinhard Ebner Interleukins-21 and 22
US20010023070A1 (en) * 1998-05-29 2001-09-20 Reinhard Ebner Interleukins-21 and 22
US7226591B2 (en) * 2000-05-22 2007-06-05 Genentech, Inc. Interleukin-22 polypeptides, nucleic acids encoding the same and methods for the treatment of pancreatic disorders
US20050148029A1 (en) * 2003-09-29 2005-07-07 Biosite, Inc. Methods and compositions for determining treatment regimens in systemic inflammatory response syndromes
CN101219208B (zh) * 2005-01-04 2010-08-11 健能隆医药技术(上海)有限公司 白介素-22的医药用途
CN100515491C (zh) * 2005-01-04 2009-07-22 健能隆医药技术(上海)有限公司 白介素-22的医药用途
AU2007261019A1 (en) * 2006-06-19 2007-12-27 Wyeth Methods of modulating IL-22 and IL-17
WO2008085229A2 (en) * 2006-11-15 2008-07-17 Arteriocyte Inc. Cell-based therapies for treating liver disease
CN101168049A (zh) * 2007-10-23 2008-04-30 中国人民解放军军事医学科学院基础医学研究所 白介素-22在制备治疗肝病药物中的应用及其制备方法

Also Published As

Publication number Publication date
AU2010203446B2 (en) 2015-12-17
EP2385841B1 (en) 2016-11-16
US20110268696A1 (en) 2011-11-03
CN102348463B (zh) 2014-05-07
CA2748392A1 (en) 2010-07-15
EP2385841A1 (en) 2011-11-16
US8956605B2 (en) 2015-02-17
JP2012515165A (ja) 2012-07-05
WO2010081112A1 (en) 2010-07-15
CA2748392C (en) 2017-06-27
AU2010203446A1 (en) 2011-07-14
CN102348463A (zh) 2012-02-08
EP2385841A4 (en) 2012-12-19

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