JP5945534B2 - グリセロールエステル活性剤送達システムおよび方法 - Google Patents

グリセロールエステル活性剤送達システムおよび方法 Download PDF

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JP5945534B2
JP5945534B2 JP2013510249A JP2013510249A JP5945534B2 JP 5945534 B2 JP5945534 B2 JP 5945534B2 JP 2013510249 A JP2013510249 A JP 2013510249A JP 2013510249 A JP2013510249 A JP 2013510249A JP 5945534 B2 JP5945534 B2 JP 5945534B2
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active agent
glycerol ester
ester
glycerol
mmol
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Japanese (ja)
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JP2013526347A5 (https=
JP2013526347A (ja
Inventor
スティーブン・ジェイ・チュジック
エミリー・アール・アール・マイヤリング
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サーモディクス，インコーポレイテッド
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L31/16—Biologically active materials, e.g. therapeutic substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/28—Materials for coating prostheses
    • A61L27/34—Macromolecular materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/54—Biologically active materials, e.g. therapeutic substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L29/00—Materials for catheters, medical tubing, cannulae, or endoscopes or for coating catheters
    • A61L29/08—Materials for coatings
    • A61L29/085—Macromolecular materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L29/00—Materials for catheters, medical tubing, cannulae, or endoscopes or for coating catheters
    • A61L29/14—Materials characterised by their function or physical properties, e.g. lubricating compositions
    • A61L29/16—Biologically active materials, e.g. therapeutic substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/08—Materials for coatings
    • A61L31/10—Macromolecular materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Dermatology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Surgery (AREA)
  • Vascular Medicine (AREA)
  • Transplantation (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Rheumatology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pain & Pain Management (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Materials For Medical Uses (AREA)
  • Medicinal Preparation (AREA)
  • Polymers & Plastics (AREA)
JP2013510249A 2010-05-10 2011-05-10 グリセロールエステル活性剤送達システムおよび方法 Active JP5945534B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US33303610P 2010-05-10 2010-05-10
US61/333,036 2010-05-10
PCT/US2011/035951 WO2011143237A1 (en) 2010-05-10 2011-05-10 Glycerol ester active agent delivery systems and methods

Publications (3)

Publication Number Publication Date
JP2013526347A JP2013526347A (ja) 2013-06-24
JP2013526347A5 JP2013526347A5 (https=) 2014-06-26
JP5945534B2 true JP5945534B2 (ja) 2016-07-05

Family

ID=44278961

Family Applications (1)

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JP2013510249A Active JP5945534B2 (ja) 2010-05-10 2011-05-10 グリセロールエステル活性剤送達システムおよび方法

Country Status (5)

Country Link
US (1) US8871819B2 (https=)
EP (1) EP2569023B1 (https=)
JP (1) JP5945534B2 (https=)
CA (1) CA2798459C (https=)
WO (1) WO2011143237A1 (https=)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9555119B2 (en) 2012-11-05 2017-01-31 Surmodics, Inc. Composition and method for delivery of hydrophobic active agents
US10213528B2 (en) 2011-05-20 2019-02-26 Surmodics, Inc. Delivery of hydrophobic active agent particles

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2569023B1 (en) 2010-05-10 2015-10-21 SurModics, Inc. Glycerol ester active agent delivery systems and methods
US11246963B2 (en) 2012-11-05 2022-02-15 Surmodics, Inc. Compositions and methods for delivery of hydrophobic active agents
US9956196B2 (en) 2014-01-26 2018-05-01 Wjwu & Lynn Institute For Stem Cell Research And Mello Biotechnology Use of monosaccharide-like glycylated sugar alcohol compositions for designing and developing anti-diabetic drugs
US10505292B2 (en) * 2016-05-24 2019-12-10 Hubbell Incorporated Oxide inhibitor capsule
US10898446B2 (en) 2016-12-20 2021-01-26 Surmodics, Inc. Delivery of hydrophobic active agents from hydrophilic polyether block amide copolymer surfaces
US12226552B2 (en) 2019-09-30 2025-02-18 Surmodics, Inc. Active agent depots formed in situ
US20220226627A1 (en) * 2021-01-15 2022-07-21 Covidien Lp Surgical stapling device with therapeutic suppository

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US3936391A (en) 1971-06-16 1976-02-03 Drackett Company Hydrated polyglycerol ester composition
NL8103356A (nl) 1981-07-15 1983-02-01 Unilever Nv Polyglycerolesters-bevattende vetmengsels en werkwijze ter onderdrukking van het ontstaan van triglycerideconglomeraten onder toepassing van polyglycerolesters.
US5002582A (en) * 1982-09-29 1991-03-26 Bio-Metric Systems, Inc. Preparation of polymeric surfaces via covalently attaching polymers
US4490421A (en) 1983-07-05 1984-12-25 E. I. Du Pont De Nemours And Company Balloon and manufacture thereof
DK406686D0 (da) * 1986-08-26 1986-08-26 Hans Bundgaard Carboxylsyrederivater
US5195969A (en) 1991-04-26 1993-03-23 Boston Scientific Corporation Co-extruded medical balloons and catheter using such balloons
DE4226174A1 (de) 1992-08-07 1994-02-10 Solvay Fluor & Derivate Polyglycerinfettsäureestergemisch
US5500180A (en) 1992-09-30 1996-03-19 C. R. Bard, Inc. Method of making a distensible dilatation balloon using a block copolymer
US5399371A (en) 1993-06-17 1995-03-21 Henkel Corporation Low calorie substitute for an edible oil
DE4480681C2 (de) 1994-02-17 2001-09-27 Scimed Life Systems Inc Verfahren zur Herstellung von Katheter-Ballonen und danach hergestellte orientierte Ballone
DE69514910T3 (de) 1994-03-02 2009-09-24 Boston Scientific Ltd., Hastings Christ Church Blockcopolymerelastomer ballon für katheter
US5585506A (en) 1994-07-22 1996-12-17 Lonza Inc. One phase production of polyglycerol esters
WO1997017098A1 (en) 1995-11-08 1997-05-15 Scimed Life Systems, Inc. Method of balloon formation by cold drawing/necking
US5891451A (en) 1996-06-25 1999-04-06 Elizabeth Arden Company, Division Of Conopco, Inc. Skin treatment with salicylic acid esters
US5728732A (en) 1996-11-27 1998-03-17 Elizabeth Arden Company, Division Of Conopco, Inc. Skin treatment with salicylic acid esters and retinoids
AU2002227308A1 (en) 2000-11-06 2002-05-15 Lonza Inc. Processes for preparing linear polyglycerols and polyglycerol esters
US7034037B2 (en) 2001-06-29 2006-04-25 Ethicon, Inc. Compositions and medical devices utilizing bioabsorbable polymeric waxes and rapamycin
WO2005063037A1 (en) 2003-12-30 2005-07-14 Gumlink A/S Chewing gum comprising biodegradable polymers and having accelerated degradability
EP1555278A1 (en) 2004-01-15 2005-07-20 Innocore Technologies B.V. Biodegradable multi-block co-polymers
JP5026956B2 (ja) * 2004-05-12 2012-09-19 サーモディクス，インコーポレイティド 医療用具のための天然生分解性多糖コーティング
US20060240194A1 (en) 2005-04-26 2006-10-26 Cargill, Incorporated Polyglycerol fatty acid ester composition and coating
CA2621595A1 (en) 2005-09-21 2007-04-12 Surmodics, Inc. Coatings and articles including natural biodegradable polysaccharides
US8663674B2 (en) * 2006-01-13 2014-03-04 Surmodics, Inc. Microparticle containing matrices for drug delivery
US20070218102A1 (en) 2006-03-15 2007-09-20 Surmodics, Inc. Biodegradable hydrophobic polysaccharide-based coatings
US8414909B2 (en) 2006-11-20 2013-04-09 Lutonix, Inc. Drug releasing coatings for medical devices
ITTO20070356A1 (it) 2007-05-21 2008-11-22 Sorin Biomedica Cardio Srl "composizione per il rilascio di principi attivi da dispositivi di impianto"
CA2730760A1 (en) 2008-07-16 2010-01-21 Surmodics Pharmaceuticals, Inc. Process for preparing microparticles containing bioactive peptides
EP2569023B1 (en) 2010-05-10 2015-10-21 SurModics, Inc. Glycerol ester active agent delivery systems and methods

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10213528B2 (en) 2011-05-20 2019-02-26 Surmodics, Inc. Delivery of hydrophobic active agent particles
US11529440B2 (en) 2011-05-20 2022-12-20 Surmodics, Inc. Delivery of hydrophobic active agent particles
US12083249B2 (en) 2011-05-20 2024-09-10 Surmodics, Inc. Delivery of hydrophobic active agent particles
US9555119B2 (en) 2012-11-05 2017-01-31 Surmodics, Inc. Composition and method for delivery of hydrophobic active agents
US9999675B2 (en) 2012-11-05 2018-06-19 Surmodics, Inc. Composition and method for delivery of hydrophobic active agents

Also Published As

Publication number Publication date
US8871819B2 (en) 2014-10-28
US20110275725A1 (en) 2011-11-10
EP2569023A1 (en) 2013-03-20
WO2011143237A1 (en) 2011-11-17
EP2569023B1 (en) 2015-10-21
CA2798459C (en) 2019-01-15
JP2013526347A (ja) 2013-06-24
CA2798459A1 (en) 2011-11-17

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