JP5943996B2 - 腫瘍溶解性強化Ｂ型ヒトアデノウイルスＡｄ１１突然変異体の構築とその応用 - Google Patents

腫瘍溶解性強化Ｂ型ヒトアデノウイルスＡｄ１１突然変異体の構築とその応用 Download PDF

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JP5943996B2
JP5943996B2 JP2014513035A JP2014513035A JP5943996B2 JP 5943996 B2 JP5943996 B2 JP 5943996B2 JP 2014513035 A JP2014513035 A JP 2014513035A JP 2014513035 A JP2014513035 A JP 2014513035A JP 5943996 B2 JP5943996 B2 JP 5943996B2
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王▲尭▼河
姜国忠
黄▲漢▼熙
曹▲風▼雨
莱蒙・尼克
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北京▲錘▼特生物科技有限公司
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    • C12N2710/10011—Adenoviridae
    • C12N2710/10311—Mastadenovirus, e.g. human or simian adenoviruses
    • C12N2710/10341—Use of virus, viral particle or viral elements as a vector
    • C12N2710/10343—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector

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JP2014513035A 2011-05-31 2012-02-29 腫瘍溶解性強化Ｂ型ヒトアデノウイルスＡｄ１１突然変異体の構築とその応用 Active JP5943996B2 (ja)

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CN201110143385.3 2011-05-31
CN2011101433853A CN102260712B (zh) 2011-05-31 2011-05-31 溶肿瘤能力增强的B型人腺病毒Ad11突变体的构建和应用
PCT/CN2012/071757 WO2012163119A1 (zh) 2011-05-31 2012-02-29 溶肿瘤能力增强的B型人腺病毒Ad11突变体的构建和应用

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JP2014523236A JP2014523236A (ja) 2014-09-11
JP2014523236A5 JP2014523236A5 (enExample) 2015-08-20
JP5943996B2 true JP5943996B2 (ja) 2016-07-05

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US (3) US9315827B2 (enExample)
EP (1) EP2716764B1 (enExample)
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WO (1) WO2012163119A1 (enExample)

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CN102260712B (zh) * 2011-05-31 2013-10-02 北京锤特生物科技有限公司 溶肿瘤能力增强的B型人腺病毒Ad11突变体的构建和应用
CA2903582C (en) 2013-03-14 2021-06-08 Salk Institute For Biological Studies Oncolytic adenovirus compositions
JP7015551B2 (ja) 2016-02-23 2022-02-15 ソーク インスティテュート フォー バイオロジカル スタディーズ ウイルス動態への影響を最小限にするための治療用アデノウイルスにおける外因性遺伝子発現
WO2017147265A1 (en) 2016-02-23 2017-08-31 Salk Institute For Biological Studies High throughput assay for measuring adenovirus replication kinetics
CN106591368A (zh) * 2016-10-12 2017-04-26 郑州大学 携带il‑15r/il‑15融合基因的b亚群腺病毒11载体及其构建和用途
CA3045892A1 (en) 2016-12-12 2018-06-21 Salk Institute For Biological Studies Tumor-targeting synthetic adenoviruses and uses thereof
CN110093323B (zh) * 2018-01-31 2024-01-30 上海元宋生物技术有限公司 重组溶瘤腺病毒OncoAd-P28GANK-E1A-△E1B及其构建方法和应用
BR112020019942A2 (pt) 2018-04-09 2021-01-26 Salk Institute For Biological Studies composições de adenovírus oncolítico com propriedades de replicação aprimoradas

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EP1816204B1 (en) * 1999-05-17 2010-10-20 Crucell Holland B.V. Recombinant Adenovirus of the Ad26 serotype
US7741099B2 (en) * 2004-10-13 2010-06-22 Beth Israel Deaconess Medical Center Inc. Adenoviral vectors and uses thereof
NZ555907A (en) * 2004-11-16 2009-12-24 Aeras Global Tb Vaccine Found Multivalent vaccines comprising recombinant viral vectors
HUE031411T2 (en) * 2007-03-02 2017-07-28 Glaxosmithkline Biologicals Sa New Methods and Preparations
CN102260712B (zh) * 2011-05-31 2013-10-02 北京锤特生物科技有限公司 溶肿瘤能力增强的B型人腺病毒Ad11突变体的构建和应用

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CN102260712B (zh) 2013-10-02
EP2716764A1 (en) 2014-04-09
US10294493B2 (en) 2019-05-21
JP2014523236A (ja) 2014-09-11
WO2012163119A1 (zh) 2012-12-06
US20140088180A1 (en) 2014-03-27
EP2716764A4 (en) 2015-01-14
CN102260712A (zh) 2011-11-30
EP2716764B1 (en) 2019-05-01
US20160222413A1 (en) 2016-08-04
US20180187214A1 (en) 2018-07-05
US9315827B2 (en) 2016-04-19
US9932606B2 (en) 2018-04-03

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