JP2014523236A5 - - Google Patents

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JP2014523236A5
JP2014523236A5 JP2014513035A JP2014513035A JP2014523236A5 JP 2014523236 A5 JP2014523236 A5 JP 2014523236A5 JP 2014513035 A JP2014513035 A JP 2014513035A JP 2014513035 A JP2014513035 A JP 2014513035A JP 2014523236 A5 JP2014523236 A5 JP 2014523236A5
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Japan
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sequence
gfp
tumor
expression cassette
gene expression
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JP2014513035A
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JP2014523236A (ja
JP5943996B2 (ja
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JP2014513035A 2011-05-31 2012-02-29 腫瘍溶解性強化B型ヒトアデノウイルスAd11突然変異体の構築とその応用 Active JP5943996B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CN201110143385.3 2011-05-31
CN2011101433853A CN102260712B (zh) 2011-05-31 2011-05-31 溶肿瘤能力增强的B型人腺病毒Ad11突变体的构建和应用
PCT/CN2012/071757 WO2012163119A1 (zh) 2011-05-31 2012-02-29 溶肿瘤能力增强的B型人腺病毒Ad11突变体的构建和应用

Publications (3)

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JP2014523236A JP2014523236A (ja) 2014-09-11
JP2014523236A5 true JP2014523236A5 (enExample) 2015-08-20
JP5943996B2 JP5943996B2 (ja) 2016-07-05

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JP2014513035A Active JP5943996B2 (ja) 2011-05-31 2012-02-29 腫瘍溶解性強化B型ヒトアデノウイルスAd11突然変異体の構築とその応用

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US (3) US9315827B2 (enExample)
EP (1) EP2716764B1 (enExample)
JP (1) JP5943996B2 (enExample)
CN (1) CN102260712B (enExample)
WO (1) WO2012163119A1 (enExample)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102260712B (zh) * 2011-05-31 2013-10-02 北京锤特生物科技有限公司 溶肿瘤能力增强的B型人腺病毒Ad11突变体的构建和应用
SG11201507393TA (en) 2013-03-14 2015-10-29 Salk Inst For Biological Studi Oncolytic adenovirus compositions
ES2899913T3 (es) 2014-09-24 2022-03-15 Salk Inst For Biological Studi Virus tumorales oncolíticos y métodos de uso
WO2017147265A1 (en) 2016-02-23 2017-08-31 Salk Institute For Biological Studies High throughput assay for measuring adenovirus replication kinetics
EP3390645B1 (en) 2016-02-23 2022-09-14 Salk Institute for Biological Studies Exogenous gene expression in therapeutic adenovirus for minimal impact on viral kinetics
CN106591368A (zh) * 2016-10-12 2017-04-26 郑州大学 携带il‑15r/il‑15融合基因的b亚群腺病毒11载体及其构建和用途
AU2017375633C1 (en) 2016-12-12 2023-04-27 Salk Institute For Biological Studies Tumor-targeting synthetic adenoviruses and uses thereof
CN110093323B (zh) * 2018-01-31 2024-01-30 上海元宋生物技术有限公司 重组溶瘤腺病毒OncoAd-P28GANK-E1A-△E1B及其构建方法和应用
BR112020019942A2 (pt) 2018-04-09 2021-01-26 Salk Institute For Biological Studies composições de adenovírus oncolítico com propriedades de replicação aprimoradas

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE519854T1 (de) * 1999-05-17 2011-08-15 Crucell Holland Bv Rekombinantes adenovirus auf basis von serotyp 48 (ad48).
US7741099B2 (en) * 2004-10-13 2010-06-22 Beth Israel Deaconess Medical Center Inc. Adenoviral vectors and uses thereof
BRPI0518933A2 (pt) * 2004-11-16 2008-12-16 Crucell Holland B V E Aeras Gl adenovÍrus recombinante defeituoso de replicaÇço, vetor de polinucleotÍdeo recombinante, vacina multivalente da tuberculose, e, uso do antÍgeno tb10.4 de mycobacterium
CN103550764A (zh) * 2007-03-02 2014-02-05 葛兰素史密丝克莱恩生物有限公司 疫苗组合物及其在刺激免疫反应中的用途
CN102260712B (zh) * 2011-05-31 2013-10-02 北京锤特生物科技有限公司 溶肿瘤能力增强的B型人腺病毒Ad11突变体的构建和应用

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