CN102260712B - 溶肿瘤能力增强的B型人腺病毒Ad11突变体的构建和应用 - Google Patents

溶肿瘤能力增强的B型人腺病毒Ad11突变体的构建和应用 Download PDF

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CN102260712B
CN102260712B CN2011101433853A CN201110143385A CN102260712B CN 102260712 B CN102260712 B CN 102260712B CN 2011101433853 A CN2011101433853 A CN 2011101433853A CN 201110143385 A CN201110143385 A CN 201110143385A CN 102260712 B CN102260712 B CN 102260712B
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CN102260712A (zh
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王尧河
姜国忠
黄汉熙
曹风雨
尼克莱蒙
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Zhengzhou University
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Priority to EP12792810.9A priority patent/EP2716764B1/en
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    • C12N2710/10341Use of virus, viral particle or viral elements as a vector
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CN2011101433853A 2011-05-31 2011-05-31 溶肿瘤能力增强的B型人腺病毒Ad11突变体的构建和应用 Active CN102260712B (zh)

Priority Applications (7)

Application Number Priority Date Filing Date Title
CN2011101433853A CN102260712B (zh) 2011-05-31 2011-05-31 溶肿瘤能力增强的B型人腺病毒Ad11突变体的构建和应用
EP12792810.9A EP2716764B1 (en) 2011-05-31 2012-02-29 Construction and application of mutant type b human adenovirus ad11 having enhanced oncolytic power
JP2014513035A JP5943996B2 (ja) 2011-05-31 2012-02-29 腫瘍溶解性強化B型ヒトアデノウイルスAd11突然変異体の構築とその応用
PCT/CN2012/071757 WO2012163119A1 (zh) 2011-05-31 2012-02-29 溶肿瘤能力增强的B型人腺病毒Ad11突变体的构建和应用
US14/093,078 US9315827B2 (en) 2011-05-31 2013-11-29 Subgroup B recombinant human adenovirus vector, and methods for constructing and for using the same
US15/098,342 US9932606B2 (en) 2011-05-31 2016-04-14 Subgroup B recombinant human adenovirus vector, and methods for constructing and for using the same
US15/904,408 US10294493B2 (en) 2011-05-31 2018-02-25 Subgroup B recombinant human adenovirus vector, and methods for constructing and for using the same

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CN2011101433853A CN102260712B (zh) 2011-05-31 2011-05-31 溶肿瘤能力增强的B型人腺病毒Ad11突变体的构建和应用

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CN102260712B true CN102260712B (zh) 2013-10-02

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WO (1) WO2012163119A1 (enExample)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102260712B (zh) * 2011-05-31 2013-10-02 北京锤特生物科技有限公司 溶肿瘤能力增强的B型人腺病毒Ad11突变体的构建和应用
CA2903582C (en) 2013-03-14 2021-06-08 Salk Institute For Biological Studies Oncolytic adenovirus compositions
JP7015551B2 (ja) 2016-02-23 2022-02-15 ソーク インスティテュート フォー バイオロジカル スタディーズ ウイルス動態への影響を最小限にするための治療用アデノウイルスにおける外因性遺伝子発現
WO2017147265A1 (en) 2016-02-23 2017-08-31 Salk Institute For Biological Studies High throughput assay for measuring adenovirus replication kinetics
CN106591368A (zh) * 2016-10-12 2017-04-26 郑州大学 携带il‑15r/il‑15融合基因的b亚群腺病毒11载体及其构建和用途
CA3045892A1 (en) 2016-12-12 2018-06-21 Salk Institute For Biological Studies Tumor-targeting synthetic adenoviruses and uses thereof
CN110093323B (zh) * 2018-01-31 2024-01-30 上海元宋生物技术有限公司 重组溶瘤腺病毒OncoAd-P28GANK-E1A-△E1B及其构建方法和应用
BR112020019942A2 (pt) 2018-04-09 2021-01-26 Salk Institute For Biological Studies composições de adenovírus oncolítico com propriedades de replicação aprimoradas

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006040330A2 (en) * 2004-10-13 2006-04-20 Crucell Holland B.V. Improved adenoviral vectors and uses thereof
CN101090974A (zh) * 2004-11-16 2007-12-19 克鲁塞尔荷兰公司 包含重组病毒载体的多价疫苗
WO2008107370A1 (en) * 2007-03-02 2008-09-12 Glaxosmithkline Biologicals S.A. Novel method and compositions

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1816204B1 (en) * 1999-05-17 2010-10-20 Crucell Holland B.V. Recombinant Adenovirus of the Ad26 serotype
CN102260712B (zh) * 2011-05-31 2013-10-02 北京锤特生物科技有限公司 溶肿瘤能力增强的B型人腺病毒Ad11突变体的构建和应用

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006040330A2 (en) * 2004-10-13 2006-04-20 Crucell Holland B.V. Improved adenoviral vectors and uses thereof
CN101090974A (zh) * 2004-11-16 2007-12-19 克鲁塞尔荷兰公司 包含重组病毒载体的多价疫苗
WO2008107370A1 (en) * 2007-03-02 2008-09-12 Glaxosmithkline Biologicals S.A. Novel method and compositions

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
刘辉等.携带RGD多肽的嵌合型腺病毒载体AD11-RGD-4C-EGFP的构建及其感染效率的研究.《第二军医大学学报》.1921,第31卷(第02期),178-182.
携带RGD多肽的嵌合型腺病毒载体AD11-RGD-4C-EGFP的构建及其感染效率的研究;刘辉等;《第二军医大学学报》;19210516;第31卷(第02期);178-182 *

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EP2716764A1 (en) 2014-04-09
US10294493B2 (en) 2019-05-21
JP2014523236A (ja) 2014-09-11
JP5943996B2 (ja) 2016-07-05
WO2012163119A1 (zh) 2012-12-06
US20140088180A1 (en) 2014-03-27
EP2716764A4 (en) 2015-01-14
CN102260712A (zh) 2011-11-30
EP2716764B1 (en) 2019-05-01
US20160222413A1 (en) 2016-08-04
US20180187214A1 (en) 2018-07-05
US9315827B2 (en) 2016-04-19
US9932606B2 (en) 2018-04-03

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