JP5925808B2 - 三環式誘導体、これらの調製方法およびこれらのキナーゼ阻害剤としての使用 - Google Patents

三環式誘導体、これらの調製方法およびこれらのキナーゼ阻害剤としての使用 Download PDF

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JP5925808B2
JP5925808B2 JP2013550832A JP2013550832A JP5925808B2 JP 5925808 B2 JP5925808 B2 JP 5925808B2 JP 2013550832 A JP2013550832 A JP 2013550832A JP 2013550832 A JP2013550832 A JP 2013550832A JP 5925808 B2 JP5925808 B2 JP 5925808B2
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cyclohepta
amino
pyrimidine
carboxamide
tetrahydropyrazolo
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JP2014503566A (ja
JP2014503566A5 (enExample
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カルダレツリ，マリーナ
カスシエツリ，フランチエスコ
ドナチ，ダニエレ
ミリツツイ，ダニロ
クアルテイエリ，フランチエスカ
シルバーニ，マルコ
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ネルビアーノ・メデイカル・サイエンシーズ・エツセ・エルレ・エルレ
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    • C07—ORGANIC CHEMISTRY
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    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
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    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
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    • A61K31/5375—1,4-Oxazines, e.g. morpholine
    • A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
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  • Hematology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Transplantation (AREA)
  • Rheumatology (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2013550832A 2011-01-26 2012-01-19 三環式誘導体、これらの調製方法およびこれらのキナーゼ阻害剤としての使用 Expired - Fee Related JP5925808B2 (ja)

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Application Number Priority Date Filing Date Title
EP11152189.4 2011-01-26
EP11152189 2011-01-26
PCT/EP2012/050765 WO2012101029A1 (en) 2011-01-26 2012-01-19 Tricyclic derivatives, process for their preparation and their use as kinase inhibitors

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JP2015203444A Division JP2016053043A (ja) 2011-01-26 2015-10-15 三環式誘導体、これらの調製方法およびこれらのキナーゼ阻害剤としての使用

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JP2014503566A JP2014503566A (ja) 2014-02-13
JP2014503566A5 JP2014503566A5 (enExample) 2015-03-05
JP5925808B2 true JP5925808B2 (ja) 2016-05-25

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JP2015203444A Withdrawn JP2016053043A (ja) 2011-01-26 2015-10-15 三環式誘導体、これらの調製方法およびこれらのキナーゼ阻害剤としての使用

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US (1) US8916577B2 (enExample)
EP (1) EP2668188B1 (enExample)
JP (2) JP5925808B2 (enExample)
ES (1) ES2586588T3 (enExample)
WO (1) WO2012101029A1 (enExample)

Cited By (1)

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US8404882B2 (en) 2009-09-25 2013-03-26 Shin-Etsu Chemical Co., Ltd. One-terminal reactive organopolysiloxane having a polyalkyleneoxide group at the omega-terminal and a method for the preparation thereof

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