JP5925679B2 - デスフェリチオシンポリエーテル類似体およびその使用 - Google Patents

デスフェリチオシンポリエーテル類似体およびその使用 Download PDF

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JP5925679B2
JP5925679B2 JP2012526728A JP2012526728A JP5925679B2 JP 5925679 B2 JP5925679 B2 JP 5925679B2 JP 2012526728 A JP2012526728 A JP 2012526728A JP 2012526728 A JP2012526728 A JP 2012526728A JP 5925679 B2 JP5925679 B2 JP 5925679B2
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salt
solvate
hydrate
compound according
compound
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JP2013503160A (ja
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レイモンド ジェイ. ジュニア バーガロン,
レイモンド ジェイ. ジュニア バーガロン,
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ユニバーシティ オブ フロリダ リサーチ ファウンデーション,インコーポレイティド
ユニバーシティ オブ フロリダ リサーチ ファウンデーション,インコーポレイティド
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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D277/00Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
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    • C07D277/08Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D277/12Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
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  • Health & Medical Sciences (AREA)
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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Polyethers (AREA)
JP2012526728A 2009-08-25 2010-08-25 デスフェリチオシンポリエーテル類似体およびその使用 Expired - Fee Related JP5925679B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US27509609P 2009-08-25 2009-08-25
US61/275,096 2009-08-25
PCT/US2010/002336 WO2011028255A2 (en) 2009-08-25 2010-08-25 Desferrithiocin polyether analogues and uses thereof

Related Child Applications (1)

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JP2015040176A Division JP2015120742A (ja) 2009-08-25 2015-03-02 デスフェリチオシンポリエーテル類似体およびその使用

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JP2013503160A JP2013503160A (ja) 2013-01-31
JP2013503160A5 JP2013503160A5 (https=) 2013-10-03
JP5925679B2 true JP5925679B2 (ja) 2016-05-25

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JP2012526728A Expired - Fee Related JP5925679B2 (ja) 2009-08-25 2010-08-25 デスフェリチオシンポリエーテル類似体およびその使用
JP2015040176A Pending JP2015120742A (ja) 2009-08-25 2015-03-02 デスフェリチオシンポリエーテル類似体およびその使用

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US (1) US20120184586A1 (https=)
EP (1) EP2470515A4 (https=)
JP (2) JP5925679B2 (https=)
CN (1) CN102574824B (https=)
AU (1) AU2010290103B2 (https=)
CA (1) CA2772212A1 (https=)
IN (1) IN2012DN02448A (https=)
WO (1) WO2011028255A2 (https=)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005034949A1 (en) 2003-09-09 2005-04-21 University Of Florida Desferrithiocin derivatives and their use as iron chelators
BRPI0610644B8 (pt) 2005-04-04 2021-05-25 Univ Florida composto e composição farmacêutica que compreende tal composto e um veículo ou diluente farmaceuticamente aceitável.
JP5439193B2 (ja) 2007-03-15 2014-03-12 ユニバーシティー オブ フロリダ リサーチ ファンデーション, インク. デスフェリチオシンポリエーテル類似体
US8063227B2 (en) 2008-07-14 2011-11-22 Ferrokin Biosciences, Inc. Salts and polymorphs of desazadesferrithiocin polyether analogues as metal chelation agents
BR112012001761A2 (pt) * 2009-07-27 2017-05-09 Ferrokin Bioscience Inc composto de formula i, composto farmacêutica e método de tratamento de uma condição mediada por metal em um indivduo
US9045440B2 (en) 2010-05-04 2015-06-02 Ferrokin Biosciences, Inc. Desazadesferrothiocin and desazadesferrothiocin polyether analogues as metal chelation agents
TW201338777A (zh) 2011-12-09 2013-10-01 Ferrokin Biosciences Inc 用於治療金屬過載之經口調配物
JP6539046B2 (ja) 2011-12-16 2019-07-03 ユニバーシティー オブ フロリダ リサーチ ファンデーション, インク. 4’−デスフェリチオシン類似体の使用
CA2930966A1 (en) * 2013-11-22 2015-05-28 University Of Florida Research Foundation, Inc. Desferrithiocin analogs and uses thereof
EP3288557A4 (en) * 2015-04-27 2018-11-07 University of Florida Research Foundation, Inc. Metabolically programmed metal chelators and uses thereof
EP3383415B1 (en) 2015-12-01 2021-03-31 Cornell University Use of mitochondrial iron chelators for treatment of chronic obstructive pulmonary disease
KR20230004944A (ko) * 2016-08-05 2023-01-06 아브페로 파마슈티칼스, 인크. 금속-매개 상태를 치료하기 위한 투여 요법
JP2021530515A (ja) * 2018-07-19 2021-11-11 ザ・リージエンツ・オブ・ザ・ユニバーシテイ・オブ・コロラド、ア・ボデイー・コーポレイト 鉄欠乏症および関連する貧血を治療するためのエンテロバクチンの新規使用のための方法、システムおよび組成物

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BRPI0610644B8 (pt) * 2005-04-04 2021-05-25 Univ Florida composto e composição farmacêutica que compreende tal composto e um veículo ou diluente farmaceuticamente aceitável.
US20100137346A1 (en) * 2006-12-12 2010-06-03 University Of Florida Research Foundation, Inc. Desferrithiocin analogue actinide decorporation agents
JP5439193B2 (ja) * 2007-03-15 2014-03-12 ユニバーシティー オブ フロリダ リサーチ ファンデーション, インク. デスフェリチオシンポリエーテル類似体

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Publication number Publication date
US20120184586A1 (en) 2012-07-19
IN2012DN02448A (https=) 2015-08-21
JP2015120742A (ja) 2015-07-02
AU2010290103B2 (en) 2016-07-14
CA2772212A1 (en) 2011-03-10
CN102574824B (zh) 2016-04-27
EP2470515A4 (en) 2013-04-24
WO2011028255A2 (en) 2011-03-10
JP2013503160A (ja) 2013-01-31
WO2011028255A3 (en) 2011-07-14
EP2470515A2 (en) 2012-07-04
CN102574824A (zh) 2012-07-11
AU2010290103A1 (en) 2012-03-29

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