JP5917490B2 - 人工涙エマルション - Google Patents

人工涙エマルション Download PDF

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Publication number
JP5917490B2
JP5917490B2 JP2013505489A JP2013505489A JP5917490B2 JP 5917490 B2 JP5917490 B2 JP 5917490B2 JP 2013505489 A JP2013505489 A JP 2013505489A JP 2013505489 A JP2013505489 A JP 2013505489A JP 5917490 B2 JP5917490 B2 JP 5917490B2
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JP
Japan
Prior art keywords
emulsion
phospholipid
emulsion according
polymer
weight
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Application number
JP2013505489A
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English (en)
Japanese (ja)
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JP2013525335A5 (https=
JP2013525335A (ja
Inventor
クロード、クラル
マルティーヌ、クラル
キャロル、ガール
ニコラ、ランプレヒト‐バイセンボルン
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Horus Pharma SAS
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Horus Pharma SAS
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Publication date
Application filed by Horus Pharma SAS filed Critical Horus Pharma SAS
Publication of JP2013525335A publication Critical patent/JP2013525335A/ja
Publication of JP2013525335A5 publication Critical patent/JP2013525335A5/ja
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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/726—Glycosaminoglycans, i.e. mucopolysaccharides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/726—Glycosaminoglycans, i.e. mucopolysaccharides
    • A61K31/728—Hyaluronic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/24—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38—Cellulose; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/04—Artificial tears; Irrigation solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/14—Decongestants or antiallergics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Ophthalmology & Optometry (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Dermatology (AREA)
  • Inorganic Chemistry (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Dispersion Chemistry (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
JP2013505489A 2010-04-21 2011-04-21 人工涙エマルション Active JP5917490B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR1053030 2010-04-21
FR1053030A FR2962044B1 (fr) 2010-04-21 2010-04-21 Emulsion lacrymimetique
PCT/EP2011/056447 WO2011131765A2 (fr) 2010-04-21 2011-04-21 Emulsion lacrymimetique

Publications (3)

Publication Number Publication Date
JP2013525335A JP2013525335A (ja) 2013-06-20
JP2013525335A5 JP2013525335A5 (https=) 2014-06-05
JP5917490B2 true JP5917490B2 (ja) 2016-05-18

Family

ID=43242426

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2013505489A Active JP5917490B2 (ja) 2010-04-21 2011-04-21 人工涙エマルション

Country Status (10)

Country Link
US (1) US9801899B2 (https=)
EP (1) EP2560616B1 (https=)
JP (1) JP5917490B2 (https=)
DK (1) DK2560616T3 (https=)
ES (1) ES2638868T3 (https=)
FR (1) FR2962044B1 (https=)
HU (1) HUE034442T2 (https=)
PL (1) PL2560616T3 (https=)
PT (1) PT2560616T (https=)
WO (1) WO2011131765A2 (https=)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9278132B2 (en) * 2012-02-13 2016-03-08 Bausch & Lomb Incorporated Ophthalmic pharmaceutical compositions and methods of making and using same
DE102014203152A1 (de) * 2014-02-21 2015-08-27 Ursapharm Arzneimittel Gmbh Mikro- oder Nanoemulsion zur ophthalmologischen Anwendung
JP6785797B2 (ja) * 2015-05-21 2020-11-18 オフタルミ モナコＯｐｈｔａｌｍｉｓ Ｍｏｎａｃｏ リポ酸および粘膜模倣ポリマーを含んでなる眼科用組成物
CA2985013C (fr) 2015-05-21 2024-04-16 Ophtalmis Monaco Association d'acide lipoique et de taurine en tant qu'agent osmoprotecteur
ITUB20152542A1 (it) 2015-07-28 2017-01-28 Altergon Sa Formulati oftalmici a base di complessi cooperativi di acido ialuronico a basso e alto peso molecolare
ES2621877B1 (es) * 2016-01-04 2018-05-04 Agencia Pública Empresarial Sanitaria Hospital De Poniente Solución para resección endoscópica
US11766421B2 (en) 2017-09-25 2023-09-26 Surface Ophthalmics, Inc. Ophthalmic pharmaceutical compositions and methods for treating ocular surface disease
KR20210141448A (ko) 2018-12-27 2021-11-23 서피스 아프샐믹스 인코포레이티드 안구 표면 질환을 치료하기 위한 안과용 약학 조성물 및 방법
MX388336B (es) * 2019-09-06 2025-03-19 Sophia Holdings S A De C V Composicion farmacéutica oftálmica, procesos de preparación y usos de las mismas
JPWO2021220712A1 (https=) * 2020-04-30 2021-11-04
EP3919047A1 (en) * 2020-06-03 2021-12-08 AZAD Pharma AG Microemulsion for the treatment of dry eye syndrome
US12310981B2 (en) 2021-05-10 2025-05-27 Surface Ophthalmics, Inc. Use of chondroitin sulfate for relieving ocular pain
US12440510B2 (en) 2021-05-10 2025-10-14 Surface Ophthalmics, Inc. Use of chondroitin sulfate for relieving ocular pain
EP4393496A4 (en) * 2021-10-29 2025-06-25 Rohto Pharmaceutical Co., Ltd. Ophthalmic composition
FR3151481A1 (fr) 2023-07-28 2025-01-31 Horus Pharma Emulsion de type huile dans eau comprenant de l’acide hyaluronique et du dexpanthenol

Family Cites Families (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU614465B2 (en) * 1989-04-05 1991-08-29 Yissum Research Development Company Of The Hebrew University Of Jerusalem Medicinal emulsions
DE4027320C2 (de) 1990-08-29 1993-09-30 Ursapharm Arzneimittel Gmbh Fluid-Abgabeeinrichtung für keimfreies Fluid
JPH0623256A (ja) * 1992-06-29 1994-02-01 Nikko Kemikaruzu Kk レシチンを利用した乳化剤及びｏ／ｗ型エマルション
US5744155A (en) * 1993-08-13 1998-04-28 Friedman; Doron Bioadhesive emulsion preparations for enhanced drug delivery
DE19527132A1 (de) * 1995-07-25 1997-01-30 Laevosan Gmbh & Co Kg Ophthalmologische Ozonschutzzusammensetzung
JP3687277B2 (ja) * 1997-06-10 2005-08-24 サンスター株式会社 美白化粧料
AU9281698A (en) * 1997-10-01 1999-04-23 Wakamoto Pharmaceutical Co., Ltd. O/w emulsion compositions
FR2816600B1 (fr) 2000-11-13 2003-03-21 Michel Faurie Dispositif distributeur de liquides goutte a goutte
DE10161110A1 (de) * 2001-12-12 2003-06-26 Ursapharm Arzneimittel Gmbh Pharmazeutische Zusammensetzung zur ophthalmologischen und rhinologischen Anwendung
DE10161149B4 (de) * 2001-12-12 2007-03-08 Ursapharm Arzneimittel Gmbh & Co. Kg Verwendung von Heparin-haltigem Ophthalmikum
CA2707068A1 (en) * 2002-09-09 2004-03-18 Santen Pharmaceutical Co., Ltd. Clear ophthalmic solution comprising latanoprost as active ingredient
FR2873358B1 (fr) 2004-07-20 2006-11-10 Sivel Soc Civ Ile Dispositif de conditionnement et distribution d'un produit avec flacon filtre sterile muni d'un embout
JP5748385B2 (ja) * 2006-01-13 2015-07-15 大正製薬株式会社 Ｏ／ｗ型エマルション水性点眼剤
ITMI20060122A1 (it) * 2006-01-25 2007-07-26 Polichem Sa Composizioni per uso vaginale
EP1834705B1 (de) 2006-03-13 2011-09-14 Ing. Erich Pfeiffer GmbH Austragvorrichtung für ein fliessfähiges Medium
ITMO20060252A1 (it) 2006-08-04 2008-02-05 Mrp Medical Res & Promotion Es Flacone per il contenimento di fluidi, particolarmente per prodotti farmaceutici o simili
JP4385170B2 (ja) * 2007-07-20 2009-12-16 ロート製薬株式会社 乳化組成物
US9034843B2 (en) * 2007-09-14 2015-05-19 Rohto Pharmaceutical Co., Ltd. Ophthalmic composition
FR2921253B1 (fr) * 2007-09-26 2012-11-16 Lvmh Rech Composition cosmetique sous la forme d'une emulsion comprenant une phase aqueuse continue et une phase grasse dispersee et son procede de preparation
JP5340954B2 (ja) * 2007-11-16 2013-11-13 テクノガード株式会社 薬物含有脂肪乳剤およびその製造方法
FR2927064B1 (fr) 2008-02-04 2010-03-26 Rexam Pharma Embout de distribution de liquide, et ensemble de conditionnement et des distribution de liquide comprenant un tel embout.
DE102008027146B4 (de) 2008-06-02 2012-01-19 Ing. Erich Pfeiffer Gmbh Austragvorrichtung
US20100303915A1 (en) * 2009-06-02 2010-12-02 Abbott Medical Optics Inc. Therapeutic opthalmic emulsions
WO2011115700A2 (en) * 2010-03-18 2011-09-22 Precision Dermatology, Inc. Emollient foams for treatment of seborrheic dermatitis
EP2377508B1 (de) * 2010-04-14 2012-10-17 PM-International AG Kosmetische O/W-Emulsion zur Hautpflege

Also Published As

Publication number Publication date
DK2560616T3 (en) 2017-10-16
EP2560616B1 (fr) 2017-07-19
WO2011131765A2 (fr) 2011-10-27
PL2560616T3 (pl) 2017-12-29
PT2560616T (pt) 2017-08-30
US20130156867A1 (en) 2013-06-20
WO2011131765A3 (fr) 2012-02-23
ES2638868T3 (es) 2017-10-24
EP2560616A2 (fr) 2013-02-27
US9801899B2 (en) 2017-10-31
FR2962044B1 (fr) 2013-02-22
HUE034442T2 (en) 2018-02-28
JP2013525335A (ja) 2013-06-20
FR2962044A1 (fr) 2012-01-06

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