JP5902478B2 - 血清中のＢＬｙＳ／ＡＰＲＩＬヘテロ三量体レベルおよび診断方法における使用 - Google Patents

血清中のＢＬｙＳ／ＡＰＲＩＬヘテロ三量体レベルおよび診断方法における使用 Download PDF

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JP5902478B2
JP5902478B2 JP2011507535A JP2011507535A JP5902478B2 JP 5902478 B2 JP5902478 B2 JP 5902478B2 JP 2011507535 A JP2011507535 A JP 2011507535A JP 2011507535 A JP2011507535 A JP 2011507535A JP 5902478 B2 JP5902478 B2 JP 5902478B2
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blys
april
antibody
levels
antagonist
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JP2011523037A (ja
JP2011523037A5 (enExample
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アール． ディロン，ステイシー
アール． ディロン，ステイシー
ジェイ． ハーダー，ブランドン
ジェイ． ハーダー，ブランドン
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ザイモジェネティクス， インコーポレイテッド
ザイモジェネティクス， インコーポレイテッド
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JP2011507535A 2008-05-01 2009-04-20 血清中のＢＬｙＳ／ＡＰＲＩＬヘテロ三量体レベルおよび診断方法における使用 Active JP5902478B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US4970608P 2008-05-01 2008-05-01
US61/049,706 2008-05-01
PCT/US2009/041089 WO2009134633A1 (en) 2008-05-01 2009-04-20 Levels of blys/april heterotrimers in serum and use in diagnostic methods

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JP2011523037A JP2011523037A (ja) 2011-08-04
JP2011523037A5 JP2011523037A5 (enExample) 2014-04-03
JP5902478B2 true JP5902478B2 (ja) 2016-04-13

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US (2) US20090274711A1 (enExample)
EP (1) EP2291657B1 (enExample)
JP (1) JP5902478B2 (enExample)
AU (1) AU2009241442B2 (enExample)
CA (1) CA2720651C (enExample)
DK (1) DK2291657T3 (enExample)
ES (1) ES2578526T3 (enExample)
HU (1) HUE028784T2 (enExample)
PL (1) PL2291657T3 (enExample)
PT (1) PT2291657T (enExample)
SI (1) SI2291657T1 (enExample)
WO (1) WO2009134633A1 (enExample)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8003335B2 (en) 2008-04-30 2011-08-23 Universite Paris-SUD11 Levels of APRIL in serum and use in diagnostic methods
AU2013234046B2 (en) * 2012-03-16 2017-09-07 University Health Network Methods and compositions for modulating Toso activity
US20170145086A1 (en) 2015-11-25 2017-05-25 Visterra, Inc. Antibody molecules to april and uses thereof
EP3694870A1 (en) 2017-10-10 2020-08-19 Alpine Immune Sciences, Inc. Ctla-4 variant immunomodulatory proteins and uses thereof
US12202882B2 (en) 2020-05-08 2025-01-21 Alpine Immune Sciences, Inc. APRIL and BAFF inhibitory immunomodulatory proteins and methods of use thereof
CN116322775A (zh) 2020-06-02 2023-06-23 阿雷斯贸易股份有限公司 IgA肾病治疗的相关方法

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10041402A1 (de) 2000-08-23 2002-03-14 Morphochem Ag Neue Verbindungen, die Faktor Xa-Aktivität inhibieren
AU2001268427B2 (en) 2000-06-16 2007-03-29 Glaxosmithkline Intellectual Property Limited Antibodies that immunospecifically bind to blys
US7189820B2 (en) * 2001-05-24 2007-03-13 Human Genome Sciences, Inc. Antibodies against tumor necrosis factor delta (APRIL)
PL403488A1 (pl) * 2001-05-24 2013-07-08 Zymogenetics, Inc. Zastosowanie bialka fuzyjnego TACI-immunoglobulina, bialko fuzyjne, czasteczka kwasu nukleinowego kodujaca bialko fuzyjne, kompozycja farmaceutyczna i sposób wytwarzania bialka fuzyjnego TACI-immunoglobulina
WO2003040307A2 (en) * 2001-07-27 2003-05-15 Human Genome Sciences, Inc. Heteromultimeric tnf ligand family members
AU2002356858A1 (en) 2001-10-24 2003-05-06 National Jewish Medical And Research Center Structure of tall-1 and its cognate receptor
ES2537738T3 (es) 2003-06-05 2015-06-11 Genentech, Inc. Terapia de combinación para trastornos de células B
WO2007030803A2 (en) * 2005-09-09 2007-03-15 Zymogenetics, Inc. Method for preparing trimeric proteins
KR20080074120A (ko) * 2005-10-13 2008-08-12 휴먼 게놈 사이언시즈, 인코포레이티드 자가항체 양성 질환 환자의 치료에 유용한 방법 및 조성물
MY150687A (en) * 2006-07-21 2014-02-28 Femalon S P R L Assay and kit for predicting implantation success in assisted fertilisation
US8003335B2 (en) 2008-04-30 2011-08-23 Universite Paris-SUD11 Levels of APRIL in serum and use in diagnostic methods

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Publication number Publication date
PT2291657T (pt) 2016-07-08
US20130330339A1 (en) 2013-12-12
EP2291657A1 (en) 2011-03-09
AU2009241442B2 (en) 2014-11-27
WO2009134633A1 (en) 2009-11-05
CA2720651A1 (en) 2009-11-05
HUE028784T2 (en) 2017-01-30
US9146242B2 (en) 2015-09-29
ES2578526T3 (es) 2016-07-27
US20090274711A1 (en) 2009-11-05
JP2011523037A (ja) 2011-08-04
PL2291657T3 (pl) 2016-09-30
CA2720651C (en) 2020-03-10
EP2291657B1 (en) 2016-04-13
SI2291657T1 (sl) 2016-09-30
DK2291657T3 (en) 2016-07-25
AU2009241442A1 (en) 2009-11-05

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