JP5893640B2 - Oprf/i試薬と入院および他の患者におけるその利用 - Google Patents

Oprf/i試薬と入院および他の患者におけるその利用 Download PDF

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Publication number
JP5893640B2
JP5893640B2 JP2013545118A JP2013545118A JP5893640B2 JP 5893640 B2 JP5893640 B2 JP 5893640B2 JP 2013545118 A JP2013545118 A JP 2013545118A JP 2013545118 A JP2013545118 A JP 2013545118A JP 5893640 B2 JP5893640 B2 JP 5893640B2
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Prior art keywords
oprf
seq
fusion protein
protein
bond
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JP2013545118A
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Japanese (ja)
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JP2014504297A5 (enExample
JP2014504297A (ja
Inventor
クレイド、クリストフ
シュレーゲル、ロベール
ヴェシュトリトシュニク、ケルスティン
Original Assignee
ファルネファ オーストリア ゲーエムベーハー
ファルネファ オーストリア ゲーエムベーハー
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/02Bacterial antigens
    • A61K39/104Pseudomonadales, e.g. Pseudomonas
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/40Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum bacterial
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/21Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Pseudomonadaceae (F)
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/12Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K19/00Hybrid peptides, i.e. peptides covalently bound to nucleic acids, or non-covalently bound protein-protein complexes

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Communicable Diseases (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2013545118A 2010-12-23 2011-03-18 Oprf/i試薬と入院および他の患者におけるその利用 Expired - Fee Related JP5893640B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201061426760P 2010-12-23 2010-12-23
US61/426,760 2010-12-23
PCT/EP2011/054127 WO2012084272A1 (en) 2010-12-23 2011-03-18 Oprf/i agents and their use in hospitalized and other patients

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2016032315A Division JP2016147867A (ja) 2010-12-23 2016-02-23 Oprf/i試薬と入院および他の患者におけるその利用

Publications (3)

Publication Number Publication Date
JP2014504297A JP2014504297A (ja) 2014-02-20
JP2014504297A5 JP2014504297A5 (enExample) 2014-04-17
JP5893640B2 true JP5893640B2 (ja) 2016-03-23

Family

ID=44210049

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2013545118A Expired - Fee Related JP5893640B2 (ja) 2010-12-23 2011-03-18 Oprf/i試薬と入院および他の患者におけるその利用
JP2016032315A Pending JP2016147867A (ja) 2010-12-23 2016-02-23 Oprf/i試薬と入院および他の患者におけるその利用

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2016032315A Pending JP2016147867A (ja) 2010-12-23 2016-02-23 Oprf/i試薬と入院および他の患者におけるその利用

Country Status (11)

Country Link
US (1) US20130266575A1 (enExample)
EP (1) EP2655402A1 (enExample)
JP (2) JP5893640B2 (enExample)
KR (1) KR20130133212A (enExample)
CN (1) CN103270047A (enExample)
AU (1) AU2011348396A1 (enExample)
BR (1) BR112013016254A2 (enExample)
CA (1) CA2822684A1 (enExample)
MX (1) MX2013007146A (enExample)
WO (1) WO2012084272A1 (enExample)
ZA (1) ZA201304235B (enExample)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2925355B1 (en) 2012-11-30 2017-11-15 GlaxoSmithKline Biologicals S.A. Pseudomonas antigens and antigen combinations
CN103983793A (zh) * 2014-05-29 2014-08-13 上海理工大学 一种含丽春红的蛋白质芯片点样缓冲液及其制备方法
US9879069B2 (en) * 2014-08-29 2018-01-30 Sorrento Therapeutics, Inc. Antibody therapeutics that bind OprF
NZ774893A (en) * 2015-05-01 2024-11-29 Inhibrx Biosciences Inc Type iii secretion system targeting molecules
WO2016193402A1 (en) 2015-06-03 2016-12-08 Valneva Austria Gmbh Pseudomonas vaccine
KR102760380B1 (ko) 2015-07-16 2025-01-31 인히브릭스 바이오사이언스, 인크. 다가 및 다중특이적 dr5-결합 융합 단백질
FR3099160B1 (fr) * 2019-07-23 2022-05-06 Univ Grenoble Alpes Anticorps dirigé contre la protéine oprf depseudomonas aeruginosa, son utilisation en tant que médicament et composition pharmaceutique le contenant
CN117222740A (zh) * 2022-06-07 2023-12-12 南方科技大学 编码PcrV和/或OprF-I蛋白的mRNA疫苗
CN116251178A (zh) * 2023-03-28 2023-06-13 吉林农业大学 一种铜绿假单胞菌疫苗及其制备方法

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5494672A (en) * 1989-04-28 1996-02-27 S.P.I. Synthetic Peptides Incorporated Pseudomonas peptide composition and method
EP0571613B1 (en) 1991-12-13 2003-09-17 Xoma Corporation Methods and materials for preparation of modified antibody variable domains and therapeutic uses thereof
ATE190657T1 (de) * 1994-12-16 2000-04-15 Chiron Behring Gmbh & Co Immunogenes hybridprotein oprf-oprl erhältlich aus membranproteinen von pseudomonas aeruginosa
US5641870A (en) 1995-04-20 1997-06-24 Genentech, Inc. Low pH hydrophobic interaction chromatography for antibody purification
EP2380906A2 (en) 1997-06-12 2011-10-26 Novartis International Pharmaceutical Ltd. Artificial antibody polypeptides
JP2005501889A (ja) * 2001-09-03 2005-01-20 アンビクス パテンツ−ライセンシーズ アーゲー マクロライド系抗生物質を用いる緑膿菌感染症の治療法
JP4481646B2 (ja) * 2001-11-13 2010-06-16 アイディー バイオメディカル コーポレーション 緑膿菌のポリペプチド
CN1756763B (zh) * 2003-01-15 2010-05-26 株式会社国际癌症免疫研究所 二聚体化肽
EP1623229A2 (en) 2003-05-15 2006-02-08 Cytos Biotechnology AG Selection of b cells with specificity of interest: method of preparation and use
GB0410958D0 (en) * 2004-05-15 2004-06-16 Haptogen Ltd Methods for reducing biofilm formation in infectious bacteria
UA91205C2 (ru) * 2004-12-17 2010-07-12 Венус Ремедиз Лимитед Антибиотическая комбинация амикацина и цефепима для создания общего раствора для лечения инфекций
EP1921142A1 (en) 2006-11-07 2008-05-14 Cytos Biotechnology AG Selection of human monoclonal antibodies by eukaryotic cell display
EP2925355B1 (en) * 2012-11-30 2017-11-15 GlaxoSmithKline Biologicals S.A. Pseudomonas antigens and antigen combinations

Also Published As

Publication number Publication date
WO2012084272A1 (en) 2012-06-28
CA2822684A1 (en) 2012-06-28
JP2016147867A (ja) 2016-08-18
AU2011348396A1 (en) 2013-07-04
KR20130133212A (ko) 2013-12-06
US20130266575A1 (en) 2013-10-10
MX2013007146A (es) 2013-11-01
JP2014504297A (ja) 2014-02-20
ZA201304235B (en) 2014-09-25
BR112013016254A2 (pt) 2017-07-11
CN103270047A (zh) 2013-08-28
EP2655402A1 (en) 2013-10-30
AU2011348396A2 (en) 2013-07-11

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