JP5887041B2 - ポリメラーゼ連鎖反応のための加圧可能なカートリッジ - Google Patents

ポリメラーゼ連鎖反応のための加圧可能なカートリッジ Download PDF

Info

Publication number
JP5887041B2
JP5887041B2 JP2013523250A JP2013523250A JP5887041B2 JP 5887041 B2 JP5887041 B2 JP 5887041B2 JP 2013523250 A JP2013523250 A JP 2013523250A JP 2013523250 A JP2013523250 A JP 2013523250A JP 5887041 B2 JP5887041 B2 JP 5887041B2
Authority
JP
Japan
Prior art keywords
sample
pcr
assembly
patent document
reaction vial
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
JP2013523250A
Other languages
English (en)
Japanese (ja)
Other versions
JP2013532488A (ja
JP2013532488A5 (enExample
Inventor
ウェイト、ブレント、エル．
ビッグモア、ウィリアム、ディー．
ズィッティング、ダリル、ケー．
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of JP2013532488A publication Critical patent/JP2013532488A/ja
Publication of JP2013532488A5 publication Critical patent/JP2013532488A5/ja
Application granted granted Critical
Publication of JP5887041B2 publication Critical patent/JP5887041B2/ja
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Images

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C12Q1/686—Polymerase chain reaction [PCR]
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/50273—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by the means or forces applied to move the fluids
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/06—Fluid handling related problems
    • B01L2200/0684—Venting, avoiding backpressure, avoid gas bubbles
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/02—Identification, exchange or storage of information
    • B01L2300/021—Identification, e.g. bar codes
    • B01L2300/022—Transponder chips
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/06—Auxiliary integrated devices, integrated components
    • B01L2300/0681—Filter
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/12—Specific details about materials
    • B01L2300/123—Flexible; Elastomeric
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0475—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure
    • B01L2400/0478—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure pistons
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502715—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by interfacing components, e.g. fluidic, electrical, optical or mechanical interfaces
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502723—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by venting arrangements
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5029—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures using swabs
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/508—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above
    • B01L3/5082—Test tubes per se
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L7/00—Heating or cooling apparatus; Heat insulating devices
    • B01L7/52—Heating or cooling apparatus; Heat insulating devices with provision for submitting samples to a predetermined sequence of different temperatures, e.g. for treating nucleic acid samples

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Clinical Laboratory Science (AREA)
  • Dispersion Chemistry (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
JP2013523250A 2010-08-02 2011-08-01 ポリメラーゼ連鎖反応のための加圧可能なカートリッジ Expired - Fee Related JP5887041B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US36992510P 2010-08-02 2010-08-02
US61/369,925 2010-08-02
PCT/US2011/046156 WO2012018741A2 (en) 2010-08-02 2011-08-01 Pressurizable cartridge for polymerase chain reactions

Publications (3)

Publication Number Publication Date
JP2013532488A JP2013532488A (ja) 2013-08-19
JP2013532488A5 JP2013532488A5 (enExample) 2015-03-12
JP5887041B2 true JP5887041B2 (ja) 2016-03-16

Family

ID=45560010

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2013523250A Expired - Fee Related JP5887041B2 (ja) 2010-08-02 2011-08-01 ポリメラーゼ連鎖反応のための加圧可能なカートリッジ

Country Status (5)

Country Link
US (1) US9816131B2 (enExample)
EP (1) EP2601286A4 (enExample)
JP (1) JP5887041B2 (enExample)
CN (1) CN103210079B (enExample)
WO (1) WO2012018741A2 (enExample)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20180071733A1 (en) * 2010-08-02 2018-03-15 Dxna Llc Pressurizable cartridge for polymerase chain reactions
DE102013200357A1 (de) * 2013-01-14 2014-07-31 Robert Bosch Gmbh Kammer zur Aufnahme einer Probe mit integrierter Schneide
EP2799137A1 (en) 2013-04-30 2014-11-05 Koninklijke Philips N.V. Fluidic system for processing a sample fluid
KR101484302B1 (ko) * 2013-11-29 2015-01-20 티엔에스(주) 밸브를 포함하는 유전자 증폭 용기, 이를 포함하는 유전자 증폭 모듈 및 이를 이용한 유전자 증폭 처리 방법.
JP6637962B2 (ja) 2014-04-24 2020-01-29 ルシラ ヘルス インコーポレイテッド 核酸増幅の比色検出方法
DE102014019526B4 (de) 2014-12-23 2016-10-27 Testo Ag Untersuchungsverfahren, scheibenförmiger Probenträger und Verwendung eines Probenträgers
CA3015377A1 (en) 2016-03-14 2017-09-21 Diassess Inc. Devices and methods for modifying optical properties
WO2017160836A1 (en) 2016-03-14 2017-09-21 Diassess Inc. Systems and methods for performing biological assays
JP6949864B2 (ja) * 2016-03-14 2021-10-13 ルシラ ヘルス インコーポレイテッド 生物学的アッセイ試料調製および送り出しのための装置および方法
EP4477316A3 (en) 2016-03-14 2025-02-19 Pfizer Inc. Selectively vented biological assay devices and associated methods
CN106701556B (zh) * 2017-01-06 2019-02-12 广东顺德永诺生物科技有限公司 数字pcr检测装置及其液路系统
US11080848B2 (en) 2017-04-06 2021-08-03 Lucira Health, Inc. Image-based disease diagnostics using a mobile device
EP3682225A4 (en) 2017-09-14 2021-06-09 Lucira Health, Inc. MULTIPLEXED ELECTRONIC-READING BIOLOGICAL DOSING DEVICE
US10549275B2 (en) 2017-09-14 2020-02-04 Lucira Health, Inc. Multiplexed biological assay device with electronic readout
CN110157590A (zh) * 2018-02-13 2019-08-23 光鼎生物科技（江苏）有限公司 热循环仪
CN109370876A (zh) * 2018-12-12 2019-02-22 深圳先进技术研究院 一种液滴数字pcr芯片及液滴数字pcr装置
USD907232S1 (en) 2018-12-21 2021-01-05 Lucira Health, Inc. Medical testing device
USD910200S1 (en) 2018-12-21 2021-02-09 Lucira Health, Inc. Test tube
US11992819B2 (en) * 2019-11-13 2024-05-28 Hepatochem Inc. Photochemistry device with a plurality of UV and visible light sources that carry out photocatalytic reactions
USD953561S1 (en) 2020-05-05 2022-05-31 Lucira Health, Inc. Diagnostic device with LED display
USD962470S1 (en) 2020-06-03 2022-08-30 Lucira Health, Inc. Assay device with LCD display
CN116457097A (zh) * 2020-12-01 2023-07-18 伊鲁米那有限公司 井凹组件和相关方法
WO2024188880A1 (en) * 2023-03-13 2024-09-19 Sefunda Ag Fluidic cartridge with a fluidic chamber

Family Cites Families (70)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3983006A (en) 1972-09-20 1976-09-28 Akro-Medic Engineering, Inc. Method for determining minimum inhibitory concentration of antibiotic
US4173447A (en) 1978-09-05 1979-11-06 Ethyl Development Corporation Apparatus for contact cooling the neck moil of blown hollow containers
JPH06101523B2 (ja) 1985-03-04 1994-12-12 株式会社日立製作所 集積回路チツプ冷却装置
US4811218A (en) 1986-06-02 1989-03-07 Applied Biosystems, Inc. Real time scanning electrophoresis apparatus for DNA sequencing
US5935522A (en) 1990-06-04 1999-08-10 University Of Utah Research Foundation On-line DNA analysis system with rapid thermal cycling
US5994056A (en) 1991-05-02 1999-11-30 Roche Molecular Systems, Inc. Homogeneous methods for nucleic acid amplification and detection
US6399397B1 (en) 1992-09-14 2002-06-04 Sri International Up-converting reporters for biological and other assays using laser excitation techniques
US5364790A (en) 1993-02-16 1994-11-15 The Perkin-Elmer Corporation In situ PCR amplification system
DE69429038T2 (de) * 1993-07-28 2002-03-21 Pe Corporation (Ny), Norwalk Vorrichtung und Verfahren zur Nukleinsäurevervielfältigung
US5538848A (en) 1994-11-16 1996-07-23 Applied Biosystems Division, Perkin-Elmer Corp. Method for detecting nucleic acid amplification using self-quenching fluorescence probe
ATE198511T1 (de) 1994-04-29 2001-01-15 Perkin Elmer Corp Verfahren und vorrichtung zur echtzeiterfassung der produkte von nukleinsäureamplifikation
US6673533B1 (en) 1995-03-10 2004-01-06 Meso Scale Technologies, Llc. Multi-array multi-specific electrochemiluminescence testing
EP0736767A1 (de) 1995-04-07 1996-10-09 Ciba-Geigy Ag Optische Detektionsvorrichtung für analytische Messungen an chemischen Substanzen
US5935524A (en) 1996-05-07 1999-08-10 E. I. Du Pont De Nemours And Company Holder for fluorometric samples
US6054277A (en) 1996-05-08 2000-04-25 Regents Of The University Of Minnesota Integrated microchip genetic testing system
PT912766E (pt) 1996-06-04 2009-07-16 Univ Utah Res Found Monitorização da hibridização durante a pcr
WO1997048818A1 (en) 1996-06-17 1997-12-24 The Board Of Trustees Of The Leland Stanford Junior University Thermocycling apparatus and method
US5854684A (en) 1996-09-26 1998-12-29 Sarnoff Corporation Massively parallel detection
DE19717085C2 (de) 1997-04-23 1999-06-17 Bruker Daltonik Gmbh Verfahren und Geräte für extrem schnelle DNA-Vervielfachung durch Polymerase-Kettenreaktionen (PCR)
US6597450B1 (en) 1997-09-15 2003-07-22 Becton, Dickinson And Company Automated Optical Reader for Nucleic Acid Assays
GB9719673D0 (en) 1997-09-17 1997-11-19 Glaxo Group Ltd Novel apparatus
US6558947B1 (en) 1997-09-26 2003-05-06 Applied Chemical & Engineering Systems, Inc. Thermal cycler
US6369893B1 (en) 1998-05-19 2002-04-09 Cepheid Multi-channel optical detection system
US6027695A (en) 1998-04-01 2000-02-22 Dupont Pharmaceuticals Company Apparatus for holding small volumes of liquids
US6605475B1 (en) 1999-04-16 2003-08-12 Perspective Biosystems, Inc. Apparatus and method for sample delivery
US6838680B2 (en) 1999-05-12 2005-01-04 Aclara Biosciences, Inc. Multiplexed fluorescent detection in microfluidic devices
US7119345B2 (en) 2003-02-28 2006-10-10 Applera Corporation Excitation and emission filter
DE60014676T2 (de) * 1999-05-28 2005-11-17 Cepheid, Sunnyvale Vorrichtung und verfahren zur analyse flüssiger proben
US6852986B1 (en) 1999-11-12 2005-02-08 E. I. Du Pont De Nemours And Company Fluorometer with low heat-generating light source
US6875619B2 (en) 1999-11-12 2005-04-05 Motorola, Inc. Microfluidic devices comprising biochannels
US6548018B2 (en) 2000-03-31 2003-04-15 Neogen Corporation Apparatus for chemiluminescent assays
US6395504B1 (en) 2000-09-01 2002-05-28 New Horizons Diagnostics Corp. Use of phage associated lytic enzymes for the rapid detection of bacterial contaminants
DE10058579A1 (de) 2000-11-18 2002-06-13 Sentronic Gmbh Ges Fuer Optisc Vorrichtung und Verfahren zur optischen Messung von Konzentrationen eines Stoffes
US20040043479A1 (en) 2000-12-11 2004-03-04 Briscoe Cynthia G. Multilayerd microfluidic devices for analyte reactions
WO2002081086A1 (en) 2001-04-09 2002-10-17 Dumas David P Transparent polymer support for organic synthesis
JP4596690B2 (ja) 2001-06-25 2010-12-08 日本電産コパル株式会社 紙葉類蛍光検出センサ
US7285424B2 (en) 2002-08-27 2007-10-23 Kimberly-Clark Worldwide, Inc. Membrane-based assay devices
WO2004029221A2 (en) * 2002-09-27 2004-04-08 The General Hospital Corporation Microfluidic device for cell separation and uses thereof
EP1558757A4 (en) * 2002-11-01 2006-06-07 Megabase Res Products GAS-RAY METHOD AND DEVICE FOR DNA HIGH-SPEED AMPLIFICATION
US7238520B2 (en) 2002-12-04 2007-07-03 Smiths Detection Inc. PCR sample preparation holder and method
US6897954B2 (en) 2002-12-20 2005-05-24 Becton, Dickinson And Company Instrument setup system for a fluorescence analyzer
US6912050B2 (en) 2003-02-03 2005-06-28 Hach Company Phase shift measurement for luminescent light
US7332347B2 (en) 2003-04-14 2008-02-19 Liang Li Apparatus and method for concentrating and collecting analytes from a flowing liquid stream
JP2005117987A (ja) 2003-10-17 2005-05-12 Thermogen Kk Ｄｎａ増幅装置
US7122799B2 (en) 2003-12-18 2006-10-17 Palo Alto Research Center Incorporated LED or laser enabled real-time PCR system and spectrophotometer
JP5007440B2 (ja) 2004-05-13 2012-08-22 ナノバイオシン， インコーポレイテッド ナノ−ｐｃｒ：核酸増幅及び検出のための方法及び装置
WO2006013926A1 (ja) 2004-08-05 2006-02-09 Universal Bio Research Co., Ltd. 反応容器、反応容器液導入装置、液導入反応測定装置、および液導入装置
DE102004063438A1 (de) 2004-12-23 2006-07-06 Oktavia Backes Neuartige mikrofluidische Probenträger
US7315376B2 (en) 2005-01-07 2008-01-01 Advanced Molecular Systems, Llc Fluorescence detection system
WO2006076742A2 (en) 2005-01-16 2006-07-20 Georgia Tech Research Corporation Methods and compositions for increasing membrane permeability
US20060188891A1 (en) 2005-02-23 2006-08-24 Bickmore William D Jr Methods and apparatus for controlling DNA amplification
WO2006132666A1 (en) 2005-06-06 2006-12-14 Decision Biomarkers, Inc. Assays based on liquid flow over arrays
TWI419717B (zh) 2005-06-17 2013-12-21 Altea Therapeutics Corp 滲透傳送系統及其使用方法
EP1943018B1 (en) 2005-09-06 2017-08-16 Thermo Fisher Scientific Oy Thermal cycler with optimized sample holder geometry
EP1951860A4 (en) 2005-11-21 2012-06-06 Life Technologies Corp PORTABLE PREPARATION, ANALYSIS AND DETECTION APPARATUS FOR THE TREATMENT OF NUCLEIC ACIDS
EP1960306A4 (en) * 2005-11-22 2014-04-02 Mycrolab Diagnostics Pty Ltd MICROFLUIDIC STRUCTURES
WO2007149696A1 (en) 2006-06-23 2007-12-27 Applera Corporation Systems and methods for cooling in biological analysis instruments
US7939312B2 (en) 2006-08-30 2011-05-10 Dxna Llc Rapid thermocycler with movable cooling assembly
US9278321B2 (en) 2006-09-06 2016-03-08 Canon U.S. Life Sciences, Inc. Chip and cartridge design configuration for performing micro-fluidic assays
US20080085541A1 (en) 2006-10-10 2008-04-10 Advanced Molecular Systems, Llc Rapid Reverse Transcription of RNA
CN101715429B (zh) * 2007-05-15 2012-05-23 和光纯药工业株式会社 均衡集成式pcr-ce微流装置内的压力的压力歧管
US8105783B2 (en) * 2007-07-13 2012-01-31 Handylab, Inc. Microfluidic cartridge
WO2009037518A1 (en) 2007-09-20 2009-03-26 Nokia Corporation A connection method for flexible board and a flexible board connector
WO2009049268A1 (en) * 2007-10-12 2009-04-16 Rheonix, Inc. Integrated microfluidic device and methods
WO2009067518A1 (en) 2007-11-20 2009-05-28 3M Innovative Properties Company Sample preparation container and method
JP5253911B2 (ja) 2008-07-28 2013-07-31 東邦チタニウム株式会社 アルコキシマグネシウムの合成方法
KR101468593B1 (ko) 2008-08-14 2014-12-04 삼성전자주식회사 기체 제거 유닛을 포함하는 파동 센서 장치 및 액체 시료 중의 표적 물질을 검출하는 방법
JP2010130925A (ja) * 2008-12-03 2010-06-17 Olympus Corp 核酸増幅方法、核酸増幅装置及び微量液体の保持方法
US9248422B2 (en) * 2010-02-23 2016-02-02 Luminex Corporation Apparatus and methods for integrated sample preparation, reaction and detection
US9481903B2 (en) * 2013-03-13 2016-11-01 Roche Molecular Systems, Inc. Systems and methods for detection of cells using engineered transduction particles

Also Published As

Publication number Publication date
US20130295663A1 (en) 2013-11-07
WO2012018741A2 (en) 2012-02-09
US9816131B2 (en) 2017-11-14
JP2013532488A (ja) 2013-08-19
CN103210079B (zh) 2015-07-22
EP2601286A4 (en) 2016-10-05
EP2601286A2 (en) 2013-06-12
CN103210079A (zh) 2013-07-17
WO2012018741A3 (en) 2012-04-26

Similar Documents

Publication Publication Date Title
JP5887041B2 (ja) ポリメラーゼ連鎖反応のための加圧可能なカートリッジ
JP6838127B2 (ja) 統合された移送モジュールを有する試験カートリッジ
EP3394293B1 (en) Sample-to-answer system for microorganism detection featuring target enrichment, amplification and detection
CN107338180B (zh) 样品制备、处理和分析系统
US8642293B2 (en) Disposable device for analyzing a liquid sample containing a nucleic acid with a nucleic acid amplification apparatus
EP3401386B1 (en) Reaction treatment device
US20150136604A1 (en) Sample preparation, processing and analysis systems
CA2799676C (en) Reaction vessel for pcr device and method of performing pcr
CN105642378A (zh) 测试盒中的多个反应腔室
CN111394234B (zh) 一种用于核酸扩增的数字化芯片及方法
US20140255270A1 (en) Removing sacrificial layer to form liquid containment structure and methods of use thereof
JP2013505010A (ja) 簡易核酸増幅装置及び簡易核酸増幅装置の使用方法
WO2009129397A2 (en) High throughput dispenser
CA2989599A1 (en) A method of detecting genetic material in a biological sample and a device for its implementation
JP5441035B2 (ja) 試料解析装置
US20230226540A1 (en) Test container, test device, and nucleic acid test method
CN104946507A (zh) 核酸扩增反应装置以及核酸扩增方法
JP2014098595A (ja) サンプル液注入用具及びサンプル液熱処理装置
US20250011851A1 (en) Test container and nucleic acid test method
US20240226876A1 (en) Testing devices
US20250010298A1 (en) Test container and nucleic acid test method
JP2010172270A (ja) マイクロ反応容器及びマイクロ反応容器を用いたポリメラーゼ連鎖反応方法
HK1096334A (en) Device having a self sealing fluid port

Legal Events

Date Code Title Description
A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20140801

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20140801

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20150123

A977 Report on retrieval

Free format text: JAPANESE INTERMEDIATE CODE: A971007

Effective date: 20150527

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20150602

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20150902

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20151002

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20151030

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20151202

TRDD Decision of grant or rejection written
A01 Written decision to grant a patent or to grant a registration (utility model)

Free format text: JAPANESE INTERMEDIATE CODE: A01

Effective date: 20151222

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20160121

A61 First payment of annual fees (during grant procedure)

Free format text: JAPANESE INTERMEDIATE CODE: A61

Effective date: 20160213

R150 Certificate of patent or registration of utility model

Ref document number: 5887041

Country of ref document: JP

Free format text: JAPANESE INTERMEDIATE CODE: R150

LAPS Cancellation because of no payment of annual fees