JP5886194B2 - インフルエンザ感染の診断および／または処置のための組成物および方法 - Google Patents

インフルエンザ感染の診断および／または処置のための組成物および方法 Download PDF

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JP5886194B2
JP5886194B2 JP2012517927A JP2012517927A JP5886194B2 JP 5886194 B2 JP5886194 B2 JP 5886194B2 JP 2012517927 A JP2012517927 A JP 2012517927A JP 2012517927 A JP2012517927 A JP 2012517927A JP 5886194 B2 JP5886194 B2 JP 5886194B2
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polypeptide
fold
binding
topology
umbrella
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JP2012532117A (ja
JP2012532117A5 (https=
Inventor
アキラ ジャヤラマン，
アキラ ジャヤラマン，
カーティック ビスワナサン，
カーティック ビスワナサン，
ラウル ラマン，
ラウル ラマン，
ザッカリー エイチ． シュリバー，
ザッカリー エイチ． シュリバー，
サシセカラン，　ラム
ラム サシセカラン，
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Massachusetts Institute of Technology
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Massachusetts Institute of Technology
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56983—Viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011—Details
    • C12N2760/16011—Orthomyxoviridae
    • C12N2760/16111—Influenzavirus A, i.e. influenza A virus
    • C12N2760/16122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/005—Assays involving biological materials from specific organisms or of a specific nature from viruses
    • G01N2333/08—RNA viruses
    • G01N2333/11—Orthomyxoviridae, e.g. influenza virus
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/50—Determining the risk of developing a disease

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Virology (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Pulmonology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
JP2012517927A 2009-07-02 2010-07-02 インフルエンザ感染の診断および／または処置のための組成物および方法 Active JP5886194B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US22288909P 2009-07-02 2009-07-02
US61/222,889 2009-07-02
PCT/US2010/040978 WO2011003100A2 (en) 2009-07-02 2010-07-02 Compositions and methods for diagnosing and/or treating influenza infection

Related Child Applications (1)

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JP2015224253A Division JP2016028107A (ja) 2009-07-02 2015-11-16 インフルエンザ感染の診断および／または処置のための組成物および方法

Publications (3)

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JP2012532117A JP2012532117A (ja) 2012-12-13
JP2012532117A5 JP2012532117A5 (https=) 2013-08-15
JP5886194B2 true JP5886194B2 (ja) 2016-03-16

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JP2012517927A Active JP5886194B2 (ja) 2009-07-02 2010-07-02 インフルエンザ感染の診断および／または処置のための組成物および方法
JP2015224253A Withdrawn JP2016028107A (ja) 2009-07-02 2015-11-16 インフルエンザ感染の診断および／または処置のための組成物および方法

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JP2015224253A Withdrawn JP2016028107A (ja) 2009-07-02 2015-11-16 インフルエンザ感染の診断および／または処置のための組成物および方法

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Country Link
US (2) US9278998B2 (https=)
EP (1) EP2448596B1 (https=)
JP (2) JP5886194B2 (https=)
AU (1) AU2010266129B2 (https=)
CA (1) CA2766899C (https=)
ES (1) ES2566361T3 (https=)
WO (1) WO2011003100A2 (https=)

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WO2011003100A2 (en) 2009-07-02 2011-01-06 Massachusetts Institute Of Technology Compositions and methods for diagnosing and/or treating influenza infection
AU2011210840B2 (en) * 2010-01-27 2014-12-11 Massachusetts Institute Of Technology Engineered polypeptide agents for targeted broad spectrum influenza neutralization
JP2013541528A (ja) 2010-09-21 2013-11-14 マサチューセッツ インスティテュート オブ テクノロジー ヒト適応ｈａポリペプチド、ワクチン、およびインフルエンザの処置
JP6029586B2 (ja) 2010-10-04 2016-11-24 マサチューセッツ インスティテュート オブ テクノロジー 血球凝集素ポリペプチド、ならびにそれに関連する試薬および方法
US9969794B2 (en) 2012-05-10 2018-05-15 Visterra, Inc. HA binding agents
CN105007938A (zh) 2013-03-15 2015-10-28 宾夕法尼亚大学理事会 流感核酸分子和由其制备的疫苗
WO2014179464A1 (en) * 2013-04-30 2014-11-06 Massachusetts Institute Of Technology Human adaptation of h3 influenza
EP3374390A1 (en) 2015-11-13 2018-09-19 Visterra, Inc. Compositions and methods for treating and preventing influenza
AU2017222564A1 (en) 2016-02-24 2018-09-06 Visterra, Inc. Formulations of antibody molecules to influenza virus
US11781112B2 (en) 2016-03-06 2023-10-10 Kareem Thomas Robinson Method of generating antigen-specific immunological memory in a subject that rejects classical vaccines
ES2991988T3 (es) 2017-10-30 2024-12-05 Takeda Pharmaceuticals Co Detergentes compatibles con el medio ambiente para la inactivación de virus con envoltura lipídica
US11230593B2 (en) 2019-03-25 2022-01-25 Visterra, Inc. Compositions and methods for treating and preventing influenza
EP4139331A4 (en) * 2020-04-22 2024-10-02 Aramis Biotechnologies Inc. SUPRASTRUCTURE WITH MODIFIED INFLUENZA HEMAGGLUTININ WITH REDUCED INTERACTION WITH SIALIC ACID

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Also Published As

Publication number Publication date
US20160266117A1 (en) 2016-09-15
CA2766899A1 (en) 2011-01-06
AU2010266129A1 (en) 2012-02-02
US9278998B2 (en) 2016-03-08
EP2448596A2 (en) 2012-05-09
WO2011003100A3 (en) 2011-02-24
JP2012532117A (ja) 2012-12-13
CA2766899C (en) 2021-05-04
WO2011003100A4 (en) 2011-04-14
US9709567B2 (en) 2017-07-18
AU2010266129B2 (en) 2016-04-14
ES2566361T3 (es) 2016-04-12
EP2448596B1 (en) 2016-01-06
JP2016028107A (ja) 2016-02-25
US20110033490A1 (en) 2011-02-10
WO2011003100A2 (en) 2011-01-06
EP2448596A4 (en) 2013-02-20

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