JP5882892B2 - 黄色ブドウ球菌エピトープＩｓａＡまたはＩｓａＢに対する抗体またはそれらのフラグメント - Google Patents

黄色ブドウ球菌エピトープＩｓａＡまたはＩｓａＢに対する抗体またはそれらのフラグメント Download PDF

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JP5882892B2
JP5882892B2 JP2012511263A JP2012511263A JP5882892B2 JP 5882892 B2 JP5882892 B2 JP 5882892B2 JP 2012511263 A JP2012511263 A JP 2012511263A JP 2012511263 A JP2012511263 A JP 2012511263A JP 5882892 B2 JP5882892 B2 JP 5882892B2
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antibody
fragment
aureus
antibodies
cell line
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JP2012527423A (ja
JP2012527423A5 (enExample
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オールセン，クヌート
ロレンツ，ウド
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Julius Maximilians Universitaet Wuerzburg
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Julius Maximilians Universitaet Wuerzburg
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/573—Immunoassay; Biospecific binding assay; Materials therefor for enzymes or isoenzymes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/40—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum bacterial
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/14—Drugs for genital or sexual disorders; Contraceptives for lactation disorders, e.g. galactorrhoea
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/12—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria
    • C07K16/1267—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-positive bacteria
    • C07K16/1271—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-positive bacteria from Micrococcaceae (F), e.g. Staphylococcus
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/40—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against enzymes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56911—Bacteria
    • G01N33/56938—Staphylococcus
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/77—Internalization into the cell
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90—Enzymes; Proenzymes
    • G01N2333/914—Hydrolases (3)
    • G01N2333/924—Hydrolases (3) acting on glycosyl compounds (3.2)
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2469/00—Immunoassays for the detection of microorganisms
    • G01N2469/10—Detection of antigens from microorganism in sample from host

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Microbiology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Food Science & Technology (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Mycology (AREA)
  • Virology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Pregnancy & Childbirth (AREA)
  • Endocrinology (AREA)
  • Communicable Diseases (AREA)
  • Reproductive Health (AREA)
JP2012511263A 2009-05-18 2010-05-18 黄色ブドウ球菌エピトープＩｓａＡまたはＩｓａＢに対する抗体またはそれらのフラグメント Expired - Fee Related JP5882892B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US17913309P 2009-05-18 2009-05-18
US61/179,133 2009-05-18
PCT/EP2010/056827 WO2010133600A1 (en) 2009-05-18 2010-05-18 Antibodies or fragments thereof directed against a staphylococcus aureus epitope of isaa or isab

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2015201433A Division JP2016047828A (ja) 2009-05-18 2015-10-09 黄色ブドウ球菌エピトープＩｓａＡまたはＩｓａＢに対する抗体またはそれらのフラグメント

Publications (3)

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JP2012527423A JP2012527423A (ja) 2012-11-08
JP2012527423A5 JP2012527423A5 (enExample) 2013-09-19
JP5882892B2 true JP5882892B2 (ja) 2016-03-09

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JP2012511263A Expired - Fee Related JP5882892B2 (ja) 2009-05-18 2010-05-18 黄色ブドウ球菌エピトープＩｓａＡまたはＩｓａＢに対する抗体またはそれらのフラグメント
JP2015201433A Pending JP2016047828A (ja) 2009-05-18 2015-10-09 黄色ブドウ球菌エピトープＩｓａＡまたはＩｓａＢに対する抗体またはそれらのフラグメント

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JP2015201433A Pending JP2016047828A (ja) 2009-05-18 2015-10-09 黄色ブドウ球菌エピトープＩｓａＡまたはＩｓａＢに対する抗体またはそれらのフラグメント

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US (3) US8609102B2 (enExample)
EP (1) EP2432804B1 (enExample)
JP (2) JP5882892B2 (enExample)
CN (1) CN102695724B (enExample)
AU (1) AU2010251156C1 (enExample)
BR (1) BRPI1010911A2 (enExample)
CA (1) CA2761886A1 (enExample)
ES (1) ES2537437T3 (enExample)
MX (1) MX2011012248A (enExample)
PL (1) PL2432804T3 (enExample)
PT (1) PT2432804E (enExample)
RU (1) RU2560415C2 (enExample)
WO (1) WO2010133600A1 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2016047828A (ja) * 2009-05-18 2016-04-07 ユリウス・マクシミリアンス−ウニヴェルジテート・ヴュルツブルクＪｕｌｉｕｓ Ｍａｘｉｍｉｌｉａｎｓ−Ｕｎｉｖｅｒｓｉｔａｅｔ Ｗｕｅｒｚｂｕｒｇ 黄色ブドウ球菌エピトープＩｓａＡまたはＩｓａＢに対する抗体またはそれらのフラグメント

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2013041707A1 (en) 2011-09-23 2013-03-28 Julius-Maximilians-Universität Würzburg Peptide or arrangement of peptides forming a staphylococcus aureus epitope binding site
US9944694B2 (en) 2013-12-13 2018-04-17 Rijksuniversiteit Groningen Antibodies against Staphylococcus aureus and uses therof
CN119176871A (zh) 2018-07-24 2024-12-24 免疫医疗有限责任公司 抗金黄色葡萄球菌凝集因子a(clfa)的抗体
KR102341805B1 (ko) * 2019-11-27 2021-12-22 주식회사 하울바이오 황색포도상구균에 특이적으로 반응하는 항-IsaA G4 항체 및 이의 용도
KR102341804B1 (ko) * 2019-11-27 2021-12-22 주식회사 하울바이오 황색포도상구균을 억제하는 항-IsaA F10 항체 및 이의 용도
US20230357373A1 (en) * 2019-12-17 2023-11-09 Mie University Methods and compositions for evaluating and treating fibrosis
WO2022250205A1 (ko) * 2021-05-25 2022-12-01 주식회사 하울바이오 항-IsaA F10 항체의 아토피 피부염 예방 및 개선 용도

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4238806A1 (en) * 1991-11-18 1993-05-27 Dainabot Co Methicillin-resistant staphylococcus aureus (MRSA)detection method - by detection of MRSA penicillin binding protein (PBP)2 antigen-antibody complex, and synthetic MRSA PBP2 peptides
FR2746398B1 (fr) * 1996-03-21 1998-04-30 Bio Merieux Anticorps specifique de staphylococcus aureaus, et utilisations
RU2144190C1 (ru) * 1998-01-13 2000-01-10 Катханов Али Муратович Способ диагностики стафилококковой инфекции
GB0014907D0 (en) * 2000-06-20 2000-08-09 Univ Sheffield Antigenic polypeptides
GB0127983D0 (en) * 2001-11-22 2002-01-16 Neutec Pharma Plc Treatment of micro-organism infection
KR20070104590A (ko) * 2005-01-10 2007-10-26 나비 바이오파마슈티컬즈 스타필로코쿠스 아우레우스 감염을 치료하는 방법
JP5882892B2 (ja) * 2009-05-18 2016-03-09 ユリウス・マクシミリアンス−ウニヴェルジテート・ヴュルツブルクＪｕｌｉｕｓ Ｍａｘｉｍｉｌｉａｎｓ−Ｕｎｉｖｅｒｓｉｔａｅｔ Ｗｕｅｒｚｂｕｒｇ 黄色ブドウ球菌エピトープＩｓａＡまたはＩｓａＢに対する抗体またはそれらのフラグメント

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2016047828A (ja) * 2009-05-18 2016-04-07 ユリウス・マクシミリアンス−ウニヴェルジテート・ヴュルツブルクＪｕｌｉｕｓ Ｍａｘｉｍｉｌｉａｎｓ−Ｕｎｉｖｅｒｓｉｔａｅｔ Ｗｕｅｒｚｂｕｒｇ 黄色ブドウ球菌エピトープＩｓａＡまたはＩｓａＢに対する抗体またはそれらのフラグメント

Also Published As

Publication number Publication date
US20120100151A1 (en) 2012-04-26
JP2016047828A (ja) 2016-04-07
RU2011146424A (ru) 2013-06-27
WO2010133600A1 (en) 2010-11-25
EP2432804B1 (en) 2015-02-25
PL2432804T3 (pl) 2015-08-31
US20160109449A1 (en) 2016-04-21
JP2012527423A (ja) 2012-11-08
AU2010251156A1 (en) 2011-11-24
RU2560415C2 (ru) 2015-08-20
US9658230B2 (en) 2017-05-23
CA2761886A1 (en) 2010-11-25
MX2011012248A (es) 2012-02-29
US9260511B2 (en) 2016-02-16
EP2432804A1 (en) 2012-03-28
ES2537437T3 (es) 2015-06-08
US20140072570A1 (en) 2014-03-13
AU2010251156C1 (en) 2015-02-05
US8609102B2 (en) 2013-12-17
CN102695724A (zh) 2012-09-26
CN102695724B (zh) 2016-08-24
PT2432804E (pt) 2015-06-25
AU2010251156B2 (en) 2014-10-09
BRPI1010911A2 (pt) 2019-09-24

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