JP5851588B2 - 生物医学止血用粉末ディスペンサ - Google Patents
生物医学止血用粉末ディスペンサ Download PDFInfo
- Publication number
- JP5851588B2 JP5851588B2 JP2014506860A JP2014506860A JP5851588B2 JP 5851588 B2 JP5851588 B2 JP 5851588B2 JP 2014506860 A JP2014506860 A JP 2014506860A JP 2014506860 A JP2014506860 A JP 2014506860A JP 5851588 B2 JP5851588 B2 JP 5851588B2
- Authority
- JP
- Japan
- Prior art keywords
- gas
- powder
- reservoir
- valve
- hose
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 239000000843 powder Substances 0.000 title claims description 162
- 230000002439 hemostatic effect Effects 0.000 title claims description 22
- 238000003860 storage Methods 0.000 claims description 59
- 238000003825 pressing Methods 0.000 claims description 51
- 239000000203 mixture Substances 0.000 claims description 44
- 229920001436 collagen Polymers 0.000 claims description 26
- 102000008186 Collagen Human genes 0.000 claims description 25
- 108010035532 Collagen Proteins 0.000 claims description 25
- 230000004044 response Effects 0.000 claims description 25
- 239000012530 fluid Substances 0.000 claims description 23
- 238000007789 sealing Methods 0.000 claims description 17
- 238000004891 communication Methods 0.000 claims description 9
- 230000000903 blocking effect Effects 0.000 claims 2
- 239000003814 drug Substances 0.000 description 82
- 229940079593 drug Drugs 0.000 description 69
- 208000031481 Pathologic Constriction Diseases 0.000 description 28
- 230000036262 stenosis Effects 0.000 description 28
- 208000037804 stenosis Diseases 0.000 description 28
- 150000002772 monosaccharides Chemical class 0.000 description 11
- 229920002683 Glycosaminoglycan Polymers 0.000 description 8
- 150000001875 compounds Chemical class 0.000 description 7
- 230000000994 depressogenic effect Effects 0.000 description 7
- 229960004072 thrombin Drugs 0.000 description 7
- 108090000190 Thrombin Proteins 0.000 description 6
- 102000013373 fibrillar collagen Human genes 0.000 description 5
- 108060002894 fibrillar collagen Proteins 0.000 description 5
- 239000008103 glucose Substances 0.000 description 5
- 230000000284 resting effect Effects 0.000 description 5
- 108010039209 Blood Coagulation Factors Proteins 0.000 description 4
- 102000015081 Blood Coagulation Factors Human genes 0.000 description 4
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 description 4
- 230000005540 biological transmission Effects 0.000 description 4
- 239000003114 blood coagulation factor Substances 0.000 description 4
- 238000000034 method Methods 0.000 description 4
- 239000002245 particle Substances 0.000 description 4
- SQDAZGGFXASXDW-UHFFFAOYSA-N 5-bromo-2-(trifluoromethoxy)pyridine Chemical compound FC(F)(F)OC1=CC=C(Br)C=N1 SQDAZGGFXASXDW-UHFFFAOYSA-N 0.000 description 3
- 229920001287 Chondroitin sulfate Polymers 0.000 description 3
- WSFSSNUMVMOOMR-UHFFFAOYSA-N Formaldehyde Chemical compound O=C WSFSSNUMVMOOMR-UHFFFAOYSA-N 0.000 description 3
- 230000008859 change Effects 0.000 description 3
- 238000006243 chemical reaction Methods 0.000 description 3
- 229940059329 chondroitin sulfate Drugs 0.000 description 3
- 230000036316 preload Effects 0.000 description 3
- CURLTUGMZLYLDI-UHFFFAOYSA-N Carbon dioxide Chemical compound O=C=O CURLTUGMZLYLDI-UHFFFAOYSA-N 0.000 description 2
- 239000005715 Fructose Substances 0.000 description 2
- 229930091371 Fructose Natural products 0.000 description 2
- RFSUNEUAIZKAJO-ARQDHWQXSA-N Fructose Chemical compound OC[C@H]1O[C@](O)(CO)[C@@H](O)[C@@H]1O RFSUNEUAIZKAJO-ARQDHWQXSA-N 0.000 description 2
- PYMYPHUHKUWMLA-LMVFSUKVSA-N Ribose Natural products OC[C@@H](O)[C@@H](O)[C@@H](O)C=O PYMYPHUHKUWMLA-LMVFSUKVSA-N 0.000 description 2
- CZMRCDWAGMRECN-UGDNZRGBSA-N Sucrose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 CZMRCDWAGMRECN-UGDNZRGBSA-N 0.000 description 2
- 229930006000 Sucrose Natural products 0.000 description 2
- 239000004809 Teflon Substances 0.000 description 2
- 229920006362 Teflon® Polymers 0.000 description 2
- HMFHBZSHGGEWLO-UHFFFAOYSA-N alpha-D-Furanose-Ribose Natural products OCC1OC(O)C(O)C1O HMFHBZSHGGEWLO-UHFFFAOYSA-N 0.000 description 2
- WQZGKKKJIJFFOK-VFUOTHLCSA-N beta-D-glucose Chemical compound OC[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-VFUOTHLCSA-N 0.000 description 2
- 230000000740 bleeding effect Effects 0.000 description 2
- 239000008280 blood Substances 0.000 description 2
- 210000004369 blood Anatomy 0.000 description 2
- 230000018044 dehydration Effects 0.000 description 2
- 238000006297 dehydration reaction Methods 0.000 description 2
- 230000000881 depressing effect Effects 0.000 description 2
- 239000000835 fiber Substances 0.000 description 2
- 239000006260 foam Substances 0.000 description 2
- 239000000463 material Substances 0.000 description 2
- 239000008194 pharmaceutical composition Substances 0.000 description 2
- 230000008569 process Effects 0.000 description 2
- 229960004793 sucrose Drugs 0.000 description 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 2
- KIUKXJAPPMFGSW-DNGZLQJQSA-N (2S,3S,4S,5R,6R)-6-[(2S,3R,4R,5S,6R)-3-Acetamido-2-[(2S,3S,4R,5R,6R)-6-[(2R,3R,4R,5S,6R)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylic acid Chemical compound CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 KIUKXJAPPMFGSW-DNGZLQJQSA-N 0.000 description 1
- 229920000945 Amylopectin Polymers 0.000 description 1
- HMFHBZSHGGEWLO-SOOFDHNKSA-N D-ribofuranose Chemical compound OC[C@H]1OC(O)[C@H](O)[C@@H]1O HMFHBZSHGGEWLO-SOOFDHNKSA-N 0.000 description 1
- 229920000045 Dermatan sulfate Polymers 0.000 description 1
- SXRSQZLOMIGNAQ-UHFFFAOYSA-N Glutaraldehyde Chemical compound O=CCCCC=O SXRSQZLOMIGNAQ-UHFFFAOYSA-N 0.000 description 1
- 241001465754 Metazoa Species 0.000 description 1
- 102000004316 Oxidoreductases Human genes 0.000 description 1
- 108090000854 Oxidoreductases Proteins 0.000 description 1
- 241000405070 Percophidae Species 0.000 description 1
- 238000010521 absorption reaction Methods 0.000 description 1
- 230000002429 anti-coagulating effect Effects 0.000 description 1
- 230000004071 biological effect Effects 0.000 description 1
- 239000001569 carbon dioxide Substances 0.000 description 1
- 229910002092 carbon dioxide Inorganic materials 0.000 description 1
- 230000001276 controlling effect Effects 0.000 description 1
- 230000008878 coupling Effects 0.000 description 1
- 238000010168 coupling process Methods 0.000 description 1
- 238000005859 coupling reaction Methods 0.000 description 1
- 238000004132 cross linking Methods 0.000 description 1
- AVJBPWGFOQAPRH-FWMKGIEWSA-L dermatan sulfate Chemical compound CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@H](OS([O-])(=O)=O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O)[C@H](C([O-])=O)O1 AVJBPWGFOQAPRH-FWMKGIEWSA-L 0.000 description 1
- 229940051593 dermatan sulfate Drugs 0.000 description 1
- 235000013681 dietary sucrose Nutrition 0.000 description 1
- 238000012377 drug delivery Methods 0.000 description 1
- 239000013013 elastic material Substances 0.000 description 1
- 238000000605 extraction Methods 0.000 description 1
- 238000005243 fluidization Methods 0.000 description 1
- 239000002783 friction material Substances 0.000 description 1
- 125000002791 glucosyl group Chemical group C1([C@H](O)[C@@H](O)[C@H](O)[C@H](O1)CO)* 0.000 description 1
- 230000006266 hibernation Effects 0.000 description 1
- 229920002674 hyaluronan Polymers 0.000 description 1
- 229960003160 hyaluronic acid Drugs 0.000 description 1
- 238000002156 mixing Methods 0.000 description 1
- 239000002086 nanomaterial Substances 0.000 description 1
- 230000002093 peripheral effect Effects 0.000 description 1
- 229920001282 polysaccharide Polymers 0.000 description 1
- 239000005017 polysaccharide Substances 0.000 description 1
- 239000012254 powdered material Substances 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 230000001105 regulatory effect Effects 0.000 description 1
- 125000000548 ribosyl group Chemical group C1([C@H](O)[C@H](O)[C@H](O1)CO)* 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 239000002904 solvent Substances 0.000 description 1
- 230000002966 stenotic effect Effects 0.000 description 1
- 239000005720 sucrose Substances 0.000 description 1
- 230000000451 tissue damage Effects 0.000 description 1
- 231100000827 tissue damage Toxicity 0.000 description 1
Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/30—Syringes for injection by jet action, without needle, e.g. for use with replaceable ampoules or carpules
- A61M5/3015—Syringes for injection by jet action, without needle, e.g. for use with replaceable ampoules or carpules for injecting a dose of particles in form of powdered drug, e.g. mounted on a rupturable membrane and accelerated by a gaseous shock wave or supersonic gas flow
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods
- A61B17/00491—Surgical glue applicators
- A61B2017/00522—Sprayers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods
- A61B2017/00535—Surgical instruments, devices or methods pneumatically or hydraulically operated
- A61B2017/00544—Surgical instruments, devices or methods pneumatically or hydraulically operated pneumatically
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/002—Packages specially adapted therefor, e.g. for syringes or needles, kits for diabetics
- A61M2005/005—Magazines with multiple ampoules directly inserted into an injection or infusion device, e.g. revolver-like magazines containing ampoules with or without needles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2202/00—Special media to be introduced, removed or treated
- A61M2202/06—Solids
- A61M2202/064—Powder
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
- A61M5/2053—Media being expelled from injector by pressurised fluid or vacuum
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Vascular Medicine (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Containers And Packaging Bodies Having A Special Means To Remove Contents (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
- Surgical Instruments (AREA)
- Medical Preparation Storing Or Oral Administration Devices (AREA)
- Feeding, Discharge, Calcimining, Fusing, And Gas-Generation Devices (AREA)
- Electrostatic Spraying Apparatus (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- External Artificial Organs (AREA)
- Materials For Medical Uses (AREA)
- Nozzles (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161479805P | 2011-04-27 | 2011-04-27 | |
| US61/479,805 | 2011-04-27 | ||
| EP11163820.1 | 2011-04-27 | ||
| EP11163820 | 2011-04-27 | ||
| PCT/EP2012/057641 WO2012146652A1 (en) | 2011-04-27 | 2012-04-26 | Biomedical haemostatic powder dispenser |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2014522255A JP2014522255A (ja) | 2014-09-04 |
| JP2014522255A5 JP2014522255A5 (enExample) | 2015-06-25 |
| JP5851588B2 true JP5851588B2 (ja) | 2016-02-03 |
Family
ID=46017856
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014506860A Expired - Fee Related JP5851588B2 (ja) | 2011-04-27 | 2012-04-26 | 生物医学止血用粉末ディスペンサ |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US9555185B2 (enExample) |
| EP (1) | EP2701611B1 (enExample) |
| JP (1) | JP5851588B2 (enExample) |
| CN (1) | CN103619265B (enExample) |
| AU (1) | AU2012247572B2 (enExample) |
| CA (1) | CA2830656C (enExample) |
| CY (1) | CY1116718T1 (enExample) |
| DK (1) | DK2701611T3 (enExample) |
| ES (1) | ES2549780T3 (enExample) |
| HR (1) | HRP20151027T1 (enExample) |
| HU (1) | HUE025719T2 (enExample) |
| PL (1) | PL2701611T3 (enExample) |
| PT (1) | PT2701611E (enExample) |
| RS (1) | RS54247B1 (enExample) |
| SI (1) | SI2701611T1 (enExample) |
| SM (1) | SMT201500253B (enExample) |
| WO (1) | WO2012146652A1 (enExample) |
Families Citing this family (34)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2764884A1 (en) * | 2013-02-11 | 2014-08-13 | Nederlandse Organisatie voor toegepast -natuurwetenschappelijk onderzoek TNO | Method and device for injecting a drug |
| US9867931B2 (en) | 2013-10-02 | 2018-01-16 | Cook Medical Technologies Llc | Therapeutic agents for delivery using a catheter and pressure source |
| WO2015062420A1 (zh) * | 2013-10-28 | 2015-05-07 | 浙江三创生物科技有限公司 | 粉末喷射方法及其装置 |
| AU2015313794B2 (en) | 2014-09-11 | 2019-08-29 | Ethicon, Inc. | Addition to a medical applicator |
| CN108883226A (zh) * | 2016-02-26 | 2018-11-23 | 普罗根尼蒂公司 | 用于准确药物递送的紧凑平台 |
| US10441761B2 (en) | 2016-07-01 | 2019-10-15 | Boston Scientific Scimed, Inc. | Delivery devices and methods |
| US10328205B2 (en) | 2016-07-07 | 2019-06-25 | Shl Medical Ag | Drug delivery device with pneumatic power pack |
| WO2018029340A1 (en) * | 2016-08-12 | 2018-02-15 | Biom'up | Hemostatic flowable |
| EP3978052A1 (en) | 2017-01-10 | 2022-04-06 | Boston Scientific Scimed, Inc. | Apparatuses and methods for delivering powdered agents |
| CN107080891A (zh) * | 2017-06-08 | 2017-08-22 | 北京环球利康科技有限公司 | 用于临床的粉颗粒喷洒装置 |
| US20190142326A1 (en) * | 2017-11-14 | 2019-05-16 | Inspired Life Medical Inc. | Devices, systems and methods for testing olfactory sensitivity |
| CA3087479A1 (en) | 2018-01-12 | 2019-07-18 | Boston Scientific Scimed, Inc. | Powder for achieving hemostasis |
| US11766546B2 (en) | 2018-01-31 | 2023-09-26 | Boston Scientific Scimed, Inc. | Apparatuses and methods for delivering powdered agents |
| IL276693B2 (en) | 2018-02-15 | 2023-11-01 | Biomup France Sas | Multi-dimensional hemostatic product and method for producing the same |
| JP7442512B2 (ja) | 2018-10-02 | 2024-03-04 | ボストン サイエンティフィック サイムド，インコーポレイテッド | 粉末剤の流体化及び送達のための機器 |
| US11833539B2 (en) | 2018-10-02 | 2023-12-05 | Boston Scientific Scimed, Inc. | Fluidization devices and methods of use |
| IL262623B2 (en) * | 2018-10-25 | 2024-05-01 | M A S Med Global Ltd | Tourniquet |
| US12258556B2 (en) | 2019-06-26 | 2025-03-25 | University Of Central Florida Research Foundation, Inc. | Integrated syringe |
| EP4545121A3 (en) | 2019-12-03 | 2025-07-16 | Boston Scientific Scimed, Inc. | Devices for delivering powdered agents |
| CN114746003A (zh) | 2019-12-03 | 2022-07-12 | 波士顿科学国际有限公司 | 用于药剂输送的医疗装置及相关的使用方法 |
| EP4021311B1 (en) | 2019-12-03 | 2024-07-10 | Boston Scientific Scimed, Inc. | Medical devices for agent delivery |
| CN114786590B (zh) | 2019-12-03 | 2025-09-19 | 波士顿科学国际有限公司 | 药剂施用医疗装置 |
| US12370353B2 (en) | 2019-12-20 | 2025-07-29 | Boston Scientific Scimed, Inc. | Agent delivery device |
| CN114867514B (zh) | 2020-01-06 | 2025-03-28 | 波士顿科学国际有限公司 | 用于输送粉末状药剂的装置 |
| WO2021141791A1 (en) | 2020-01-06 | 2021-07-15 | Boston Scientific Scimed, Inc. | Agent delivery systems |
| EP4106826A1 (en) | 2020-02-18 | 2022-12-28 | Boston Scientific Scimed, Inc. | Hemostatic compositions and related methods |
| US12290250B2 (en) | 2020-03-06 | 2025-05-06 | Boston Scientific Scimed, Inc. | Devices and methods for delivering powdered agents |
| KR20220157438A (ko) * | 2020-03-24 | 2022-11-29 | 보스톤 싸이엔티픽 싸이메드 인코포레이티드 | 약제 전달 시스템 및 그 사용 방법 |
| US12285539B2 (en) | 2020-04-17 | 2025-04-29 | Boston Scientific Scimed, Inc. | Hemostatic compositions and related methods |
| WO2021247850A2 (en) | 2020-06-05 | 2021-12-09 | Cook Medical Technologies Llc | Medical scopes for delivering therapeutic agents |
| CN116171177A (zh) | 2020-08-19 | 2023-05-26 | 波士顿科学国际有限公司 | 输送装置及其使用方法 |
| CN112516442B (zh) * | 2020-11-10 | 2022-11-29 | 东南大学 | 止血药快速发射装置 |
| CN113069970B (zh) * | 2021-03-30 | 2022-08-19 | 深圳市通量检测科技有限公司 | 一种食品检测样品用智能存放系统 |
| US12496429B2 (en) | 2022-10-18 | 2025-12-16 | Cook Medical Technologies Llc | Systems and methods for delivering pressurized fluid to a target site alone or in conjunction with therapeutic agents |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2017276A (en) * | 1933-05-31 | 1935-10-15 | Adolph E Ericson | Hypodermic syringe-air operated |
| ES2192573T3 (es) * | 1994-01-21 | 2003-10-16 | Powderject Vaccines Inc | Instrumento de deposito de genes mediante arrastre gaseoso. |
| JP3853360B2 (ja) * | 1994-10-24 | 2006-12-06 | パウダージェクト リサーチ リミテッド | 粒子供給装置 |
| US5656035A (en) | 1995-04-25 | 1997-08-12 | Avoy; Donald R. | Refillable fibrinogen dispensing kit |
| JP3434396B2 (ja) * | 1995-06-30 | 2003-08-04 | 株式会社日立ユニシアオートモティブ | 鼻腔用投薬器 |
| US5779100A (en) * | 1996-08-07 | 1998-07-14 | Johnson Research & Development Corp, Inc. | Vacuum actuated replenishing water gun |
| EP0963178A4 (en) * | 1997-01-30 | 2000-03-01 | Boston Scient Corp | PNEUMATIC TISSUE SAMPLING DEVICE |
| ATE462683T1 (de) | 2002-04-26 | 2010-04-15 | Basf Se | C sb 10 /sb -alkanolalkoxylat-gemische und ihre verwendung |
| FR2863503A1 (fr) | 2003-12-12 | 2005-06-17 | Genzyme Sas | Dispositif de pulverisation d'une poudre |
| RU2377022C9 (ru) | 2004-01-30 | 2010-08-10 | Ферросан А/С | Гемостатические спреи и композиции |
| KR20040052811A (ko) | 2004-04-30 | 2004-06-23 | 이민구 | 지혈 스프레이 |
| JP4439517B2 (ja) * | 2004-05-13 | 2010-03-24 | 株式会社ネクスト２１ | 経内視鏡手術に用いる止血と、癒着の防止装置 |
| US7517355B2 (en) | 2005-09-08 | 2009-04-14 | Medafor, Incorporated | Method of supporting and/or applying particulate materials |
| US8118777B2 (en) * | 2009-05-29 | 2012-02-21 | Cook Medical Technologies Llc | Systems and methods for delivering therapeutic agents |
-
2012
- 2012-04-26 CA CA2830656A patent/CA2830656C/en not_active Expired - Fee Related
- 2012-04-26 AU AU2012247572A patent/AU2012247572B2/en not_active Ceased
- 2012-04-26 HR HRP20151027TT patent/HRP20151027T1/hr unknown
- 2012-04-26 HU HUE12717284A patent/HUE025719T2/en unknown
- 2012-04-26 PT PT127172849T patent/PT2701611E/pt unknown
- 2012-04-26 JP JP2014506860A patent/JP5851588B2/ja not_active Expired - Fee Related
- 2012-04-26 US US14/007,794 patent/US9555185B2/en not_active Expired - Fee Related
- 2012-04-26 PL PL12717284T patent/PL2701611T3/pl unknown
- 2012-04-26 CN CN201280031977.9A patent/CN103619265B/zh not_active Expired - Fee Related
- 2012-04-26 SI SI201230328T patent/SI2701611T1/sl unknown
- 2012-04-26 WO PCT/EP2012/057641 patent/WO2012146652A1/en not_active Ceased
- 2012-04-26 EP EP12717284.9A patent/EP2701611B1/en active Active
- 2012-04-26 RS RS20150608A patent/RS54247B1/sr unknown
- 2012-04-26 ES ES12717284.9T patent/ES2549780T3/es active Active
- 2012-04-26 DK DK12717284.9T patent/DK2701611T3/en active
-
2015
- 2015-09-28 CY CY20151100858T patent/CY1116718T1/el unknown
- 2015-10-14 SM SM201500253T patent/SMT201500253B/it unknown
Also Published As
| Publication number | Publication date |
|---|---|
| PT2701611E (pt) | 2015-10-30 |
| HRP20151027T1 (hr) | 2015-10-23 |
| SMT201500253B (it) | 2016-01-08 |
| DK2701611T3 (en) | 2015-10-05 |
| RS54247B1 (sr) | 2016-02-29 |
| ES2549780T3 (es) | 2015-11-02 |
| JP2014522255A (ja) | 2014-09-04 |
| AU2012247572A1 (en) | 2013-11-07 |
| EP2701611B1 (en) | 2015-07-15 |
| CY1116718T1 (el) | 2017-03-15 |
| PL2701611T3 (pl) | 2016-04-29 |
| HUE025719T2 (en) | 2016-04-28 |
| CN103619265A (zh) | 2014-03-05 |
| US20140018729A1 (en) | 2014-01-16 |
| CN103619265B (zh) | 2016-04-06 |
| US9555185B2 (en) | 2017-01-31 |
| CA2830656A1 (en) | 2012-11-01 |
| CA2830656C (en) | 2019-05-28 |
| EP2701611A1 (en) | 2014-03-05 |
| WO2012146652A1 (en) | 2012-11-01 |
| SI2701611T1 (sl) | 2015-11-30 |
| AU2012247572B2 (en) | 2016-03-17 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP5851588B2 (ja) | 生物医学止血用粉末ディスペンサ | |
| US11717619B2 (en) | Hemostatic powder delivery devices and methods | |
| JP7142621B2 (ja) | ３つのチャンバを有する自動注射器 | |
| JP2007517636A5 (enExample) | ||
| CN101912648A (zh) | 用于注射所分配剂量的液体药物的设备 | |
| CN114746027A (zh) | 用于药物输送的医疗装置及相关使用方法 | |
| CN114728135B (zh) | 用于输送粉末化药剂的装置和方法 | |
| JP7696395B2 (ja) | 複式逆止弁の片手操作式アプリケータ | |
| JP2017533798A (ja) | 薬品分注器 | |
| US12465698B2 (en) | Devices and methods for delivering powdered agents | |
| CA2922993A1 (en) | Single use intranasal atomizer | |
| BR112013027563A2 (pt) | dispositivo para entregar um pó a um sítio alvo e kit |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20150427 |
|
| A621 | Written request for application examination |
Free format text: JAPANESE INTERMEDIATE CODE: A621 Effective date: 20150427 |
|
| A871 | Explanation of circumstances concerning accelerated examination |
Free format text: JAPANESE INTERMEDIATE CODE: A871 Effective date: 20150427 |
|
| A975 | Report on accelerated examination |
Free format text: JAPANESE INTERMEDIATE CODE: A971005 Effective date: 20150609 |
|
| A131 | Notification of reasons for refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A131 Effective date: 20150710 |
|
| A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20151006 |
|
| TRDD | Decision of grant or rejection written | ||
| A01 | Written decision to grant a patent or to grant a registration (utility model) |
Free format text: JAPANESE INTERMEDIATE CODE: A01 Effective date: 20151106 |
|
| A61 | First payment of annual fees (during grant procedure) |
Free format text: JAPANESE INTERMEDIATE CODE: A61 Effective date: 20151202 |
|
| R150 | Certificate of patent or registration of utility model |
Ref document number: 5851588 Country of ref document: JP Free format text: JAPANESE INTERMEDIATE CODE: R150 |
|
| R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
| R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
| LAPS | Cancellation because of no payment of annual fees |