JP2007517636A5 - - Google Patents
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- Publication number
- JP2007517636A5 JP2007517636A5 JP2006549651A JP2006549651A JP2007517636A5 JP 2007517636 A5 JP2007517636 A5 JP 2007517636A5 JP 2006549651 A JP2006549651 A JP 2006549651A JP 2006549651 A JP2006549651 A JP 2006549651A JP 2007517636 A5 JP2007517636 A5 JP 2007517636A5
- Authority
- JP
- Japan
- Prior art keywords
- drug
- mouthpiece
- dose
- cartridge
- ribbon
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000003814 drug Substances 0.000 claims 26
- 229940079593 drug Drugs 0.000 claims 24
- 239000000843 powder Substances 0.000 claims 6
- 210000000214 mouth Anatomy 0.000 claims 5
- 238000012377 drug delivery Methods 0.000 claims 4
- 239000013583 drug formulation Substances 0.000 claims 4
- 238000010304 firing Methods 0.000 claims 2
- 239000011248 coating agent Substances 0.000 claims 1
- 238000000576 coating method Methods 0.000 claims 1
- 230000037431 insertion Effects 0.000 claims 1
- 238000003780 insertion Methods 0.000 claims 1
- 230000002093 peripheral effect Effects 0.000 claims 1
- 230000001960 triggered effect Effects 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US53726604P | 2004-01-16 | 2004-01-16 | |
| PCT/US2005/001351 WO2005072803A1 (en) | 2004-01-16 | 2005-01-18 | Sublingual drug delivery device |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2007517636A JP2007517636A (ja) | 2007-07-05 |
| JP2007517636A5 true JP2007517636A5 (enExample) | 2007-08-16 |
| JP4601627B2 JP4601627B2 (ja) | 2010-12-22 |
Family
ID=34825920
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006549651A Expired - Fee Related JP4601627B2 (ja) | 2004-01-16 | 2005-01-18 | 舌下薬物送達デバイス |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US7658721B2 (enExample) |
| EP (1) | EP1711220A1 (enExample) |
| JP (1) | JP4601627B2 (enExample) |
| AU (1) | AU2005209199B2 (enExample) |
| CA (1) | CA2553392A1 (enExample) |
| WO (1) | WO2005072803A1 (enExample) |
Families Citing this family (62)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9006175B2 (en) | 1999-06-29 | 2015-04-14 | Mannkind Corporation | Potentiation of glucose elimination |
| US7080644B2 (en) * | 2000-06-28 | 2006-07-25 | Microdose Technologies, Inc. | Packaging and delivery of pharmaceuticals and drugs |
| US6923175B2 (en) | 2002-03-20 | 2005-08-02 | Mannkind Corporation | Inhalation apparatus |
| MXPA06009516A (es) | 2004-02-24 | 2007-03-26 | Microdose Technologies Inc | Inhalador con sensor de flujo direccional. |
| CN101010305B (zh) | 2004-08-20 | 2010-08-11 | 曼金德公司 | 二酮哌嗪合成的催化反应 |
| BR122019022692B1 (pt) | 2004-08-23 | 2023-01-10 | Mannkind Corporation | Composição terapêutica em pó seco contendo dicetopiperazina, pelo menos um tipo de cátion e um agente biologicamente ativo |
| KR101384456B1 (ko) | 2005-09-14 | 2014-04-10 | 맨카인드 코포레이션 | 활성제에 대한 결정질 미립자 표면의 친화력의 증가를 기반으로 하는 약물 제제화의 방법 |
| US8252329B2 (en) | 2007-01-05 | 2012-08-28 | Acelrx Pharmaceuticals, Inc. | Bioadhesive drug formulations for oral transmucosal delivery |
| US8357114B2 (en) | 2006-01-06 | 2013-01-22 | Acelrx Pharmaceuticals, Inc. | Drug dispensing device with flexible push rod |
| US8865743B2 (en) | 2006-01-06 | 2014-10-21 | Acelrx Pharmaceuticals, Inc. | Small volume oral transmucosal dosage forms containing sufentanil for treatment of pain |
| US8202535B2 (en) | 2006-01-06 | 2012-06-19 | Acelrx Pharmaceuticals, Inc. | Small-volume oral transmucosal dosage forms |
| US8753308B2 (en) | 2006-01-06 | 2014-06-17 | Acelrx Pharmaceuticals, Inc. | Methods for administering small volume oral transmucosal dosage forms using a dispensing device |
| ES2647080T3 (es) | 2006-02-22 | 2017-12-19 | Mannkind Corporation | Un método para mejorar las propiedades farmacéuticas de micropartículas que comprenden dicetopiperazina y un agente activo |
| US8579868B2 (en) * | 2006-07-15 | 2013-11-12 | Novo Nordisk A/S | Medical delivery system with flexible blocking element |
| US8672897B2 (en) | 2006-11-21 | 2014-03-18 | Novo Nordisk A/S | Medical delivery system comprising locking ring with L-shaped grooves |
| JP5503292B2 (ja) * | 2007-01-05 | 2014-05-28 | エーセルアールエックス ファーマシューティカルズ, インコーポレイテッド | 経粘膜剤形の投与のための貯蔵および投与デバイス |
| US9119777B2 (en) | 2008-05-30 | 2015-09-01 | Microdose Therapeutx, Inc. | Methods and compositions for administration of oxybutynin |
| US8415390B2 (en) | 2008-05-30 | 2013-04-09 | Microdose Therapeutx, Inc. | Methods and compositions for administration of oxybutynin |
| JP2010532241A (ja) * | 2007-07-06 | 2010-10-07 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | 吸入器 |
| US8439033B2 (en) | 2007-10-09 | 2013-05-14 | Microdose Therapeutx, Inc. | Inhalation device |
| WO2011163272A1 (en) | 2010-06-21 | 2011-12-29 | Mannkind Corporation | Dry powder drug delivery system and methods |
| DE102007056263A1 (de) | 2007-11-22 | 2009-05-28 | Siegfried Generics International Ag | Dosiervorrichtung zur Inhalierung einer pulverförmigen Substanz |
| US8371294B2 (en) * | 2008-02-29 | 2013-02-12 | Microdose Therapeutx, Inc. | Method and apparatus for driving a transducer of an inhalation device |
| DK2293833T3 (en) | 2008-06-13 | 2016-05-23 | Mannkind Corp | DRY POWDER INHALER AND MEDICINAL ADMINISTRATION SYSTEM |
| US8485180B2 (en) | 2008-06-13 | 2013-07-16 | Mannkind Corporation | Dry powder drug delivery system |
| CA2728523C (en) | 2008-06-20 | 2020-03-10 | Mannkind Corporation | An interactive apparatus and method for real-time profiling of inhalation efforts |
| TWI532497B (zh) | 2008-08-11 | 2016-05-11 | 曼凱公司 | 超快起作用胰島素之用途 |
| US8314106B2 (en) | 2008-12-29 | 2012-11-20 | Mannkind Corporation | Substituted diketopiperazine analogs for use as drug delivery agents |
| CN102405074B (zh) | 2009-02-23 | 2014-08-13 | 日本烟草产业株式会社 | 非加热型香味吸引器 |
| CA2754595C (en) | 2009-03-11 | 2017-06-27 | Mannkind Corporation | Apparatus, system and method for measuring resistance of an inhaler |
| WO2010107761A1 (en) | 2009-03-18 | 2010-09-23 | Acelrx Pharmaceuticals, Inc. | Improved storage and dispensing devices for administration of oral transmucosal dosage forms |
| US9018190B2 (en) | 2009-03-27 | 2015-04-28 | Adocia | Functionalized oligosaccharides |
| FR2943538B1 (fr) | 2009-03-27 | 2011-05-20 | Adocia | Formulation a action rapide d'insuline recombinante humaine |
| US20100286587A1 (en) * | 2009-05-07 | 2010-11-11 | Yossi Gross | Sublingual electrical drug delivery |
| US8985101B2 (en) | 2009-05-21 | 2015-03-24 | Microdose Therapeutx, Inc. | Method and device for clamping a blister within a dry powder inhaler |
| WO2010135672A1 (en) * | 2009-05-21 | 2010-11-25 | Microdose Therapeutx, Inc. | Rotary cassette system for dry powder inhaler |
| US8551528B2 (en) | 2009-06-12 | 2013-10-08 | Mannkind Corporation | Diketopiperazine microparticles with defined specific surface areas |
| US20110000481A1 (en) * | 2009-07-01 | 2011-01-06 | Anand Gumaste | Nebulizer for infants and respiratory compromised patients |
| JP5784622B2 (ja) | 2009-11-03 | 2015-09-24 | マンカインド コーポレ−ション | 吸入活動をシミュレートするための装置及び方法 |
| JP6017961B2 (ja) | 2010-01-05 | 2016-11-02 | マイクロドース セラピューテクス,インコーポレイテッド | 吸入デバイスおよび方法 |
| ES2625858T3 (es) | 2011-04-01 | 2017-07-20 | Mannkind Corporation | Paquete de tipo blíster para cartuchos farmacéuticos |
| ITBO20110289A1 (it) * | 2011-05-20 | 2012-11-21 | Health Robotics Srl | Scatola di contenimento di una sacca per prodotti farmaceutici |
| WO2012174472A1 (en) | 2011-06-17 | 2012-12-20 | Mannkind Corporation | High capacity diketopiperazine microparticles |
| HK1201475A1 (en) | 2011-10-24 | 2015-09-04 | Mannkind Corporation | Methods and compositions for treating pain |
| US20130231281A1 (en) | 2011-11-02 | 2013-09-05 | Adocia | Rapid acting insulin formulation comprising an oligosaccharide |
| CA3098386C (en) | 2012-07-12 | 2022-11-29 | Mannkind Corporation | Dry powder drug delivery systems and methods |
| EP2911690A1 (en) | 2012-10-26 | 2015-09-02 | MannKind Corporation | Inhalable influenza vaccine compositions and methods |
| KR102367083B1 (ko) | 2012-11-13 | 2022-02-24 | 아도시아 | 치환된 음이온성 화합물을 포함하는 속효성 인슐린 제형 |
| MX369136B (es) | 2013-03-15 | 2019-10-30 | Mannkind Corp | Composiciones de dicetopiperazina microcristalina y metodos. |
| BR122019026637B1 (pt) | 2013-07-18 | 2023-09-26 | Mannkind Corporation | Formulações farmacêuticas de pó seco e método para a fabricação de uma formulação de pó seco |
| US11446127B2 (en) | 2013-08-05 | 2022-09-20 | Mannkind Corporation | Insufflation apparatus and methods |
| WO2015148905A1 (en) | 2014-03-28 | 2015-10-01 | Mannkind Corporation | Use of ultrarapid acting insulin |
| FR3020947B1 (fr) | 2014-05-14 | 2018-08-31 | Adocia | Composition aqueuse comprenant au moins une proteine et un agent solubilisant, sa preparation et ses utilisations |
| US9795678B2 (en) | 2014-05-14 | 2017-10-24 | Adocia | Fast-acting insulin composition comprising a substituted anionic compound and a polyanionic compound |
| US10561806B2 (en) | 2014-10-02 | 2020-02-18 | Mannkind Corporation | Mouthpiece cover for an inhaler |
| SG11201704797TA (en) | 2014-12-23 | 2017-07-28 | Acelrx Pharmaceuticals Inc | Systems, devices and methods for dispensing oral transmucosal dosage forms |
| CN113143769A (zh) | 2015-10-30 | 2021-07-23 | 阿塞尔Rx制药有限公司 | 用于分配口腔经粘膜剂型的设备和方法 |
| FR3043557B1 (fr) | 2015-11-16 | 2019-05-31 | Adocia | Composition a action rapide d'insuline comprenant un citrate substitue |
| WO2018071427A1 (en) | 2016-10-11 | 2018-04-19 | Microdose Therapeutx, Inc. | Inhaler and methods of use thereof |
| WO2018162641A1 (en) * | 2017-03-09 | 2018-09-13 | N-Lab Marcin Binkowski | Intra-oral scanning device, method of operating such a device and scanner system |
| CN112237666B (zh) * | 2019-07-17 | 2022-06-17 | 东莞市爱的仕机电设备有限公司 | 一种雾化器及雾化器用的舌下喷嘴 |
| US11607508B1 (en) | 2020-12-23 | 2023-03-21 | Stat Capsule Inc. | Device for sublingual application of a therapeutic dose of medication in fractions |
Family Cites Families (58)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE247684C (enExample) | ||||
| GB1479283A (en) * | 1973-07-23 | 1977-07-13 | Bespak Industries Ltd | Inhaler for powdered medicament |
| US4211769A (en) | 1977-08-24 | 1980-07-08 | Takeda Chemical Industries, Ltd. | Preparations for vaginal administration |
| US4196196A (en) | 1978-06-19 | 1980-04-01 | Tiholiz Ivan C | Divalen/monovalent bipolar cation therapy for enhancement of tissue perfusion and reperfusion in disease states |
| DK147437A (en) | 1980-02-11 | 1900-01-01 | Process for preparing human insulin or threonine B30 esters of human insulin, or a salt or complex thereof | |
| DE3942145A1 (de) | 1989-12-20 | 1991-06-27 | Boehringer Mannheim Gmbh | T-pa-solubilisierung |
| AU653026B2 (en) | 1991-06-07 | 1994-09-15 | Teikoku Seiyaku Kabushiki Kaisha | Physiologically active polypeptide-containing pharmaceutical composition |
| DE4142238A1 (de) * | 1991-12-20 | 1993-06-24 | Boehringer Ingelheim Kg | Pulverinhalator mit pulvertraeger aus regelmaessigen mikrostrukturen |
| US5819726A (en) * | 1993-01-29 | 1998-10-13 | Aradigm Corporation | Method for the delivery of aerosolized drugs to the lung for the treatment of respiratory disease |
| US5888477A (en) | 1993-01-29 | 1999-03-30 | Aradigm Corporation | Use of monomeric insulin as a means for improving the bioavailability of inhaled insulin |
| US5441060A (en) * | 1993-02-08 | 1995-08-15 | Duke University | Dry powder delivery system |
| US5497763A (en) * | 1993-05-21 | 1996-03-12 | Aradigm Corporation | Disposable package for intrapulmonary delivery of aerosolized formulations |
| EP0804174A4 (en) | 1993-07-21 | 1998-09-09 | Univ Kentucky Res Found | MULTI-CHAMBER HARD CAPSULES WITH CONTROLLED DELIVERY CHARACTERISTICS |
| US5534488A (en) | 1993-08-13 | 1996-07-09 | Eli Lilly And Company | Insulin formulation |
| US5388572A (en) * | 1993-10-26 | 1995-02-14 | Tenax Corporation (A Connecticut Corp.) | Dry powder medicament inhalator having an inhalation-activated piston to aerosolize dose and deliver same |
| US5461031A (en) | 1994-06-16 | 1995-10-24 | Eli Lilly And Company | Monomeric insulin analog formulations |
| US5474978A (en) | 1994-06-16 | 1995-12-12 | Eli Lilly And Company | Insulin analog formulations |
| BR9508964A (pt) * | 1994-09-21 | 1998-06-02 | Inhale Therapeutic Syst | Processo e aparelho de aerossolização conjunto de tubo de alimentação e receptáculo para contenção de um medicamento pulverizado |
| US5653987A (en) | 1995-05-16 | 1997-08-05 | Modi; Pankaj | Liquid formulations for proteinic pharmaceuticals |
| US5849322A (en) | 1995-10-23 | 1998-12-15 | Theratech, Inc. | Compositions and methods for buccal delivery of pharmaceutical agents |
| US5912014A (en) | 1996-03-15 | 1999-06-15 | Unigene Laboratories, Inc. | Oral salmon calcitonin pharmaceutical products |
| AUPO066096A0 (en) | 1996-06-26 | 1996-07-18 | Peptide Delivery Systems Pty Ltd | Oral delivery of peptides |
| DE19647947A1 (de) * | 1996-11-20 | 1998-05-28 | Pfeiffer Erich Gmbh & Co Kg | Austragvorrichtung für Medien |
| AU6611998A (en) | 1997-03-20 | 1998-10-20 | Novo Nordisk A/S | Therapeutic powder formulation for pulmonary administration, containing crystalline insulin |
| AU742591B2 (en) | 1997-03-20 | 2002-01-10 | Novo Nordisk A/S | Zinc free insulin crystals for use in pulmonary compositions |
| US5898028A (en) | 1997-03-20 | 1999-04-27 | Novo Nordisk A/S | Method for producing powder formulation comprising an insulin |
| EP0969860B1 (en) | 1997-03-20 | 2002-07-17 | Novo Nordisk A/S | Method for preparation of a therapeutic powder through coprecipitation of insulin and absorption enhancer |
| US6310038B1 (en) | 1997-03-20 | 2001-10-30 | Novo Nordisk A/S | Pulmonary insulin crystals |
| WO1999016417A1 (en) | 1997-10-01 | 1999-04-08 | Flemington Pharmaceutical Corporation | Buccal, polar and non-polar spray or capsule |
| US6116238A (en) * | 1997-12-02 | 2000-09-12 | Dura Pharmaceuticals, Inc. | Dry powder inhaler |
| US6125844A (en) * | 1998-04-30 | 2000-10-03 | Westwood Biomedical | Portable oxygen based drug delivery system |
| US6257233B1 (en) * | 1998-06-04 | 2001-07-10 | Inhale Therapeutic Systems | Dry powder dispersing apparatus and methods for their use |
| GB9820937D0 (en) * | 1998-09-26 | 1998-11-18 | Glaxo Group Ltd | Inhalation device |
| US6248363B1 (en) | 1999-11-23 | 2001-06-19 | Lipocine, Inc. | Solid carriers for improved delivery of active ingredients in pharmaceutical compositions |
| EP2280004B1 (en) | 1999-06-29 | 2016-04-20 | MannKind Corporation | Pharmaceutical formulations comprising insulin complexed with a diketopiperazine |
| US6606992B1 (en) * | 1999-06-30 | 2003-08-19 | Nektar Therapeutics | Systems and methods for aerosolizing pharmaceutical formulations |
| US6264981B1 (en) | 1999-10-27 | 2001-07-24 | Anesta Corporation | Oral transmucosal drug dosage using solid solution |
| ES2239426T3 (es) * | 1999-12-03 | 2005-09-16 | Mattern, Udo | Combinacion de un dispositivo para la inyeccion de antiparasitarios en animales domesticos y un principio activo antiparasitario. |
| US7069929B2 (en) * | 2000-02-01 | 2006-07-04 | Quadrant Technologies Limited | Dry powder inhaler |
| US6465425B1 (en) | 2000-02-10 | 2002-10-15 | Alkermes Controlled Therapeutics, Inc. | Microencapsulation and sustained release of biologically active acid-stable or free sulfhydryl-containing proteins |
| CA2401288A1 (en) * | 2000-02-28 | 2001-09-07 | Vectura Limited | Improvements in or relating to the delivery of oral drugs |
| CN1141974C (zh) | 2000-06-07 | 2004-03-17 | 张昊 | 结肠定位释放的口服生物制剂 |
| DE10114178A1 (de) | 2001-03-23 | 2002-10-10 | Aventis Pharma Gmbh | Zinkfreie und zinkarme Insulinzubereitungen mit verbesserter Stabilität |
| US6766799B2 (en) * | 2001-04-16 | 2004-07-27 | Advanced Inhalation Research, Inc. | Inhalation device |
| WO2002092154A1 (en) * | 2001-04-26 | 2002-11-21 | New England Pharmaceuticals, Inc. | Metered dose delivery device for liquid and powder agents |
| GB0125135D0 (en) * | 2001-10-19 | 2001-12-12 | Glaxo Group Ltd | Medicament dispenser |
| US7931022B2 (en) * | 2001-10-19 | 2011-04-26 | Respirks, Inc. | Method and apparatus for dispensing inhalator medicament |
| WO2003061744A1 (en) * | 2002-01-25 | 2003-07-31 | Glaxo Group Limited | Medicament dispenser |
| US7255102B2 (en) * | 2002-02-01 | 2007-08-14 | Generex Pharmaceuticals Inc. | Metered dose spray device for use with macromolecular pharmaceutical agents such as insulin |
| EP1490031A1 (en) * | 2002-03-07 | 2004-12-29 | Vectura Limited | Fast melt multiparticulate formulations for oral delivery |
| EP1506003A1 (en) | 2002-05-07 | 2005-02-16 | Novo Nordisk A/S | Soluble formulations comprising insulin aspart and insulin detemir |
| GB0216831D0 (en) * | 2002-07-19 | 2002-08-28 | Glaxo Group Ltd | Medicament dispenser |
| AU2004220544B2 (en) | 2003-03-06 | 2010-06-17 | Emisphere Technologies, Inc. | Oral insulin therapies and protocol |
| KR101066788B1 (ko) * | 2003-04-09 | 2011-09-21 | 노바르티스 아게 | 공기 입구 차폐 부재를 갖춘 에어로졸화 장치 |
| US20050203001A1 (en) | 2004-03-05 | 2005-09-15 | Emisphere Technologies, Inc. | Oral insulin therapies and protocol |
| EP1701714A2 (en) | 2004-01-07 | 2006-09-20 | Nektar Therapeutics | Improved sustained release compositions for pulmonary administration of insulin |
| CA2626357A1 (en) | 2005-10-20 | 2007-04-26 | Nastech Pharmaceutical Company Inc. | Intranasal administration of rapid acting insulin |
| US8093207B2 (en) | 2005-12-09 | 2012-01-10 | Unigene Laboratories, Inc. | Fast-acting oral peptide pharmaceutical products |
-
2005
- 2005-01-18 CA CA002553392A patent/CA2553392A1/en not_active Abandoned
- 2005-01-18 US US11/037,737 patent/US7658721B2/en not_active Expired - Fee Related
- 2005-01-18 EP EP05705773A patent/EP1711220A1/en not_active Withdrawn
- 2005-01-18 AU AU2005209199A patent/AU2005209199B2/en not_active Ceased
- 2005-01-18 JP JP2006549651A patent/JP4601627B2/ja not_active Expired - Fee Related
- 2005-01-18 WO PCT/US2005/001351 patent/WO2005072803A1/en not_active Ceased
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