JP5781540B2 - 強化排出装置設計 - Google Patents

強化排出装置設計 Download PDF

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Publication number
JP5781540B2
JP5781540B2 JP2012546246A JP2012546246A JP5781540B2 JP 5781540 B2 JP5781540 B2 JP 5781540B2 JP 2012546246 A JP2012546246 A JP 2012546246A JP 2012546246 A JP2012546246 A JP 2012546246A JP 5781540 B2 JP5781540 B2 JP 5781540B2
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JP
Japan
Prior art keywords
enhanced
correction member
siphon
discharge device
pressure drop
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
JP2012546246A
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English (en)
Japanese (ja)
Other versions
JP2013515577A (ja
Inventor
ベンジャミン ステッドマン，
ベンジャミン ステッドマン，
プラシャント カカデ，
プラシャント カカデ，
ダレル ウォーラー，
ダレル ウォーラー，
ジョン レオナード，
ジョン レオナード，
Original Assignee
マップ・ファーマシューティカルズ・インコーポレイテッド
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Publication of JP2013515577A publication Critical patent/JP2013515577A/ja
Application granted granted Critical
Publication of JP5781540B2 publication Critical patent/JP5781540B2/ja
Expired - Fee Related legal-status Critical Current
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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0091—Inhalators mechanically breath-triggered
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0001—Details of inhalators; Constructional features thereof
    • A61M15/0021—Mouthpieces therefor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0001—Details of inhalators; Constructional features thereof
    • A61M15/0021—Mouthpieces therefor
    • A61M15/0025—Mouthpieces therefor with caps
    • A61M15/0026—Hinged caps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/009—Inhalators using medicine packages with incorporated spraying means, e.g. aerosol cans
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F25/00—Flow mixers; Mixers for falling materials, e.g. solid particles
    • B01F25/30—Injector mixers
    • B01F25/31—Injector mixers in conduits or tubes through which the main component flows
    • B01F25/312—Injector mixers in conduits or tubes through which the main component flows with Venturi elements; Details thereof
    • B01F25/3124—Injector mixers in conduits or tubes through which the main component flows with Venturi elements; Details thereof characterised by the place of introduction of the main flow
    • B01F25/31242—Injector mixers in conduits or tubes through which the main component flows with Venturi elements; Details thereof characterised by the place of introduction of the main flow the main flow being injected in the central area of the venturi, creating an aspiration in the circumferential part of the conduit
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F04—POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
    • F04F—PUMPING OF FLUID BY DIRECT CONTACT OF ANOTHER FLUID OR BY USING INERTIA OF FLUID TO BE PUMPED; SIPHONS
    • F04F5/00—Jet pumps, i.e. devices in which flow is induced by pressure drop caused by velocity of another fluid flow
    • F04F5/44—Component parts, details, or accessories not provided for in, or of interest apart from, groups F04F5/02 - F04F5/42
    • F04F5/46—Arrangements of nozzles
    • F04F5/463—Arrangements of nozzles with provisions for mixing
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F15—FLUID-PRESSURE ACTUATORS; HYDRAULICS OR PNEUMATICS IN GENERAL
    • F15D—FLUID DYNAMICS, i.e. METHODS OR MEANS FOR INFLUENCING THE FLOW OF GASES OR LIQUIDS
    • F15D1/00—Influencing flow of fluids
    • F15D1/02—Influencing flow of fluids in pipes or conduits
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0091—Inhalators mechanically breath-triggered
    • A61M15/0096—Hindering inhalation before activation of the dispenser
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2206/00—Characteristics of a physical parameter; associated device therefor
    • A61M2206/10—Flow characteristics
    • A61M2206/16—Rotating swirling helical flow, e.g. by tangential inflows
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2206/00—Characteristics of a physical parameter; associated device therefor
    • A61M2206/10—Flow characteristics
    • A61M2206/20—Flow characteristics having means for promoting or enhancing the flow, actively or passively

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Physics & Mathematics (AREA)
  • Fluid Mechanics (AREA)
  • Mechanical Engineering (AREA)
  • General Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Jet Pumps And Other Pumps (AREA)
JP2012546246A 2009-12-23 2010-12-23 強化排出装置設計 Expired - Fee Related JP5781540B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US28478409P 2009-12-23 2009-12-23
US61/284,784 2009-12-23
PCT/US2010/062084 WO2011079310A1 (en) 2009-12-23 2010-12-23 Enhanced eductor design

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2015140719A Division JP6157542B2 (ja) 2009-12-23 2015-07-14 強化排出装置設計

Publications (2)

Publication Number Publication Date
JP2013515577A JP2013515577A (ja) 2013-05-09
JP5781540B2 true JP5781540B2 (ja) 2015-09-24

Family

ID=44185936

Family Applications (3)

Application Number Title Priority Date Filing Date
JP2012546246A Expired - Fee Related JP5781540B2 (ja) 2009-12-23 2010-12-23 強化排出装置設計
JP2015140719A Active JP6157542B2 (ja) 2009-12-23 2015-07-14 強化排出装置設計
JP2017110588A Pending JP2017164554A (ja) 2009-12-23 2017-06-05 強化排出装置設計

Family Applications After (2)

Application Number Title Priority Date Filing Date
JP2015140719A Active JP6157542B2 (ja) 2009-12-23 2015-07-14 強化排出装置設計
JP2017110588A Pending JP2017164554A (ja) 2009-12-23 2017-06-05 強化排出装置設計

Country Status (9)

Country Link
US (4) US9227030B2 (cg-RX-API-DMAC7.html)
EP (1) EP2515978B1 (cg-RX-API-DMAC7.html)
JP (3) JP5781540B2 (cg-RX-API-DMAC7.html)
CN (1) CN102686261B (cg-RX-API-DMAC7.html)
AU (1) AU2010336338B2 (cg-RX-API-DMAC7.html)
CA (1) CA2781313C (cg-RX-API-DMAC7.html)
IL (3) IL219744A (cg-RX-API-DMAC7.html)
IN (1) IN2012DN04857A (cg-RX-API-DMAC7.html)
WO (1) WO2011079310A1 (cg-RX-API-DMAC7.html)

Families Citing this family (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003080149A2 (en) 2002-03-20 2003-10-02 Mannkind Corporation Inhalation apparatus
EP1786784B1 (en) 2004-08-20 2010-10-27 MannKind Corporation Catalysis of diketopiperazine synthesis
CN104436170B (zh) 2004-08-23 2018-02-23 曼金德公司 用于药物输送的二酮哌嗪盐
IN2014DN09128A (cg-RX-API-DMAC7.html) 2005-09-14 2015-07-10 Mannkind Corp
CN101389348A (zh) 2006-02-22 2009-03-18 曼金德公司 用于改善包含二酮哌嗪和活性剂的微粒的药物性质的方法
WO2008023013A1 (en) * 2006-08-22 2008-02-28 Glaxo Group Limited Actuator for an inhaler
CA2661270A1 (en) * 2006-08-22 2008-02-28 Glaxo Group Limited Actuator for an inhaler
US8875697B2 (en) * 2007-07-24 2014-11-04 Ric Investments, Llc Drug delivery apparatus and method
US9358352B2 (en) * 2008-06-13 2016-06-07 Mannkind Corporation Dry powder drug delivery system and methods
US8485180B2 (en) 2008-06-13 2013-07-16 Mannkind Corporation Dry powder drug delivery system
CN109568740B (zh) 2008-06-13 2022-05-27 曼金德公司 干粉吸入器和用于药物输送的系统
BR122020002400B1 (pt) 2008-06-20 2021-12-07 Mannkind Corporation Sistema de detecção de inalação de pó seco e sistema de monitoramento acoplável para um inalador de pó seco
US8314106B2 (en) 2008-12-29 2012-11-20 Mannkind Corporation Substituted diketopiperazine analogs for use as drug delivery agents
GB2476611B (en) * 2009-08-07 2011-08-31 Kind Consumer Ltd An inhaler
US9227030B2 (en) * 2009-12-23 2016-01-05 Map Pharmaceuticals, Inc. Enhanced eductor design
JP6133270B2 (ja) 2011-04-01 2017-05-24 マンカインド コーポレイション 薬剤カートリッジのためのブリスター包装
WO2012174472A1 (en) 2011-06-17 2012-12-20 Mannkind Corporation High capacity diketopiperazine microparticles
HK1201475A1 (en) 2011-10-24 2015-09-04 Mannkind Corporation Methods and compositions for treating pain
CA2878457C (en) 2012-07-12 2021-01-19 Mannkind Corporation Dry powder drug delivery systems and methods
EP2890437B1 (en) * 2012-08-29 2019-12-18 Chiesi Farmaceutici S.p.A. Aerosol inhalation device
CA3056509C (en) * 2013-03-14 2021-11-16 Trudell Medical International Metered dose inhaler applicator
WO2014183073A1 (en) * 2013-05-10 2014-11-13 Loec, Inc. Flavor vortex device
GB201308679D0 (en) * 2013-05-14 2013-06-26 3M Innovative Properties Co Actuator for an inhaler
EP3021834A1 (en) 2013-07-18 2016-05-25 MannKind Corporation Heat-stable dry powder pharmaceutical compositions and methods
US10307464B2 (en) 2014-03-28 2019-06-04 Mannkind Corporation Use of ultrarapid acting insulin
CN103877655B (zh) * 2014-04-08 2015-12-30 隋宁昕 自吸固定式吸氧鼻塞
WO2016089981A1 (en) * 2014-12-04 2016-06-09 Carefusion 2200, Inc. Breath-actuated nebulizer for medicine inhalation
US12357776B2 (en) 2015-12-21 2025-07-15 Kindeva Drug Delivery L.P. Medicinal inhalers
GB201702407D0 (en) * 2017-02-14 2017-03-29 Norton (Waterford) Ltd Inhalers and related methods
GB201707095D0 (en) * 2017-05-04 2017-06-21 3M Innovative Properties Co Inhaler flow control mechanism
CN109210374B (zh) * 2017-06-30 2021-06-08 北京北方华创微电子装备有限公司 进气管路及半导体加工设备
CA3095939C (en) * 2018-04-06 2023-09-26 Frank Levy Apparatus and method for producing an enriched medical suspension
CN110433366B (zh) * 2019-08-12 2022-03-04 杭州市红十字会医院 一种便携式呼吸科给药器
CN113898570B (zh) * 2021-12-08 2022-02-08 常州萨柏美格医用气体设备有限公司 气体流动过程检测装置及方法、空气压缩机组及检测方法
CN114798201B (zh) * 2022-06-29 2022-10-04 山东沃德净水科技有限公司 一种喷射器优化方法及喷射器
WO2025030129A2 (en) * 2023-08-03 2025-02-06 United Industries Corporation Aerosol spray device, insecticide composition, and method of use
US12268807B1 (en) 2023-12-20 2025-04-08 Yale University Devices, systems, and methods for providing individualized delivery of suspended medication

Family Cites Families (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2037940A (en) 1932-09-10 1936-04-21 Edward A Stalker Means for preventing the separation of the flow from curved surfaces
US3665949A (en) 1969-06-27 1972-05-30 Bendix Corp Gaseous controlled fluidic throttling valve
YU41046B (en) * 1974-08-22 1986-10-31 Schering Ag Medicine inholating device
US4044763A (en) * 1975-07-07 1977-08-30 Bird F M Ventilator and method
US4592348A (en) * 1984-12-17 1986-06-03 Waters Iv William C Aerosol inhaler
FR2645026B1 (fr) * 1989-03-31 1997-11-21 Boussignac Georges Dispositif d'assistance respiratoire
US5404871A (en) * 1991-03-05 1995-04-11 Aradigm Delivery of aerosol medications for inspiration
US5161524A (en) * 1991-08-02 1992-11-10 Glaxo Inc. Dosage inhalator with air flow velocity regulating means
US5785049A (en) 1994-09-21 1998-07-28 Inhale Therapeutic Systems Method and apparatus for dispersion of dry powder medicaments
KR950703379A (ko) 1992-09-11 1995-09-20 알란 헤스케쓰 흡입 장치(Inhalation Device)
SG82544A1 (en) * 1993-08-18 2001-08-21 Fisons Plc Inhalator with breath flow regulation
US5415162A (en) * 1994-01-18 1995-05-16 Glaxo Inc. Multi-dose dry powder inhalation device
HU220472B1 (hu) * 1994-09-21 2002-02-28 Inhale Therapeutic Systems Eljárás és készülék por aeroszolosítására, valamint a készülékben alkalmazott adagolócső-egység
US6006747A (en) * 1997-03-20 1999-12-28 Dura Pharmaceuticals, Inc. Dry powder inhaler
US5954047A (en) 1997-10-17 1999-09-21 Systemic Pulmonary Development, Ltd. Methods and apparatus for delivering aerosolized medication
JP3530004B2 (ja) * 1998-02-06 2004-05-24 株式会社日立ユニシアオートモティブ 吸入式投薬器
DK1649886T3 (da) * 1999-07-23 2008-05-05 Mannkind Corp Enhedsdosiskapsler til törpulverinhalatorer
US6367471B1 (en) 1999-11-01 2002-04-09 Sheffield Pharmaceuticals, Inc. Internal vortex mechanism for inhaler device
US6443151B1 (en) * 2000-03-08 2002-09-03 Aradigm Corporation Fluid velocity-sensitive trigger mechanism
DE10024738A1 (de) 2000-05-19 2001-11-29 Qvf Engineering Gmbh Glasbauteile mit einer ableitfähigen Beschichtung, ihre Verwendung und daraus hergestellte Apparate, Anlagen und Rohrleitungen
GB0016478D0 (en) * 2000-07-05 2000-08-23 Innovata Biomed Ltd Valve
GB2364919A (en) 2000-07-21 2002-02-13 Cambridge Consultants Inhalers
FI20002363A0 (fi) 2000-10-27 2000-10-27 Orion Yhtymae Oyj Jauheinhalaattori
GB0222295D0 (en) * 2002-09-25 2002-10-30 3M Innovative Properties Co Breath actuated medicament dispensing devices
DE102005010965B3 (de) * 2005-03-10 2006-08-03 Medspray Xmems Bv Inhalator mit einem Mischkanal zum Erzeugen eines zu inhalierenden Aerosols
DE102006014433A1 (de) * 2006-03-27 2007-10-04 Boehringer Ingelheim Pharma Gmbh & Co. Kg Dosieraerosole für die Verabreichung von pharmazeutischen Zubereitungen
EP3034119B1 (en) * 2006-03-30 2018-03-21 Vyaire Medical Consumables LLC Nebulizer with pressure-based fluidic-control
US7841335B2 (en) * 2006-03-30 2010-11-30 Carefusion 2200, Inc. Nebulizer with flow-based fluidic control and related methods
CN101636232A (zh) * 2007-02-28 2010-01-27 艾博特呼吸有限责任公司 基于喷嘴的雾化系统
JP5462152B2 (ja) * 2008-04-17 2014-04-02 帝人ファーマ株式会社 定量噴霧式吸入器用吸入補助器具
CN109568740B (zh) * 2008-06-13 2022-05-27 曼金德公司 干粉吸入器和用于药物输送的系统
US9227030B2 (en) * 2009-12-23 2016-01-05 Map Pharmaceuticals, Inc. Enhanced eductor design

Also Published As

Publication number Publication date
IL242205A0 (en) 2015-11-30
US9610415B2 (en) 2017-04-04
AU2010336338A1 (en) 2012-06-21
IL219744A0 (en) 2012-07-31
EP2515978A1 (en) 2012-10-31
IL252847B (en) 2021-02-28
CN102686261B (zh) 2014-09-10
CA2781313A1 (en) 2011-06-30
JP2013515577A (ja) 2013-05-09
JP2017164554A (ja) 2017-09-21
EP2515978B1 (en) 2018-02-14
AU2010336338B2 (en) 2015-02-19
IL242205A (en) 2017-07-31
US20170056609A1 (en) 2017-03-02
US20160129208A1 (en) 2016-05-12
CA2781313C (en) 2019-09-17
JP6157542B2 (ja) 2017-07-05
IL252847A0 (en) 2017-08-31
US20110155129A1 (en) 2011-06-30
WO2011079310A1 (en) 2011-06-30
US20200030555A1 (en) 2020-01-30
US9227030B2 (en) 2016-01-05
CN102686261A (zh) 2012-09-19
EP2515978A4 (en) 2015-03-04
IL219744A (en) 2015-11-30
JP2015221225A (ja) 2015-12-10
IN2012DN04857A (cg-RX-API-DMAC7.html) 2015-09-25

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