CN102686261B - 增强型的喷射器设计 - Google Patents

增强型的喷射器设计 Download PDF

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Publication number
CN102686261B
CN102686261B CN201080058137.2A CN201080058137A CN102686261B CN 102686261 B CN102686261 B CN 102686261B CN 201080058137 A CN201080058137 A CN 201080058137A CN 102686261 B CN102686261 B CN 102686261B
Authority
CN
China
Prior art keywords
injector
constriction
length
physical dimension
siphon
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CN201080058137.2A
Other languages
English (en)
Chinese (zh)
Other versions
CN102686261A (zh
Inventor
B·斯特德曼
P·卡卡德
D·韦勒
J·伦纳德
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
MAP Pharmaceuticals Inc
Original Assignee
MAP Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by MAP Pharmaceuticals Inc filed Critical MAP Pharmaceuticals Inc
Publication of CN102686261A publication Critical patent/CN102686261A/zh
Application granted granted Critical
Publication of CN102686261B publication Critical patent/CN102686261B/zh
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/0091Inhalators mechanically breath-triggered
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/0001Details of inhalators; Constructional features thereof
    • A61M15/0021Mouthpieces therefor
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/0001Details of inhalators; Constructional features thereof
    • A61M15/0021Mouthpieces therefor
    • A61M15/0025Mouthpieces therefor with caps
    • A61M15/0026Hinged caps
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/009Inhalators using medicine packages with incorporated spraying means, e.g. aerosol cans
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01FMIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F25/00Flow mixers; Mixers for falling materials, e.g. solid particles
    • B01F25/30Injector mixers
    • B01F25/31Injector mixers in conduits or tubes through which the main component flows
    • B01F25/312Injector mixers in conduits or tubes through which the main component flows with Venturi elements; Details thereof
    • B01F25/3124Injector mixers in conduits or tubes through which the main component flows with Venturi elements; Details thereof characterised by the place of introduction of the main flow
    • B01F25/31242Injector mixers in conduits or tubes through which the main component flows with Venturi elements; Details thereof characterised by the place of introduction of the main flow the main flow being injected in the central area of the venturi, creating an aspiration in the circumferential part of the conduit
    • FMECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F04POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
    • F04FPUMPING OF FLUID BY DIRECT CONTACT OF ANOTHER FLUID OR BY USING INERTIA OF FLUID TO BE PUMPED; SIPHONS
    • F04F5/00Jet pumps, i.e. devices in which flow is induced by pressure drop caused by velocity of another fluid flow
    • F04F5/44Component parts, details, or accessories not provided for in, or of interest apart from, groups F04F5/02 - F04F5/42
    • F04F5/46Arrangements of nozzles
    • F04F5/463Arrangements of nozzles with provisions for mixing
    • FMECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F15FLUID-PRESSURE ACTUATORS; HYDRAULICS OR PNEUMATICS IN GENERAL
    • F15DFLUID DYNAMICS, i.e. METHODS OR MEANS FOR INFLUENCING THE FLOW OF GASES OR LIQUIDS
    • F15D1/00Influencing flow of fluids
    • F15D1/02Influencing flow of fluids in pipes or conduits
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/0091Inhalators mechanically breath-triggered
    • A61M15/0096Hindering inhalation before activation of the dispenser
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2206/00Characteristics of a physical parameter; associated device therefor
    • A61M2206/10Flow characteristics
    • A61M2206/16Rotating swirling helical flow, e.g. by tangential inflows
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2206/00Characteristics of a physical parameter; associated device therefor
    • A61M2206/10Flow characteristics
    • A61M2206/20Flow characteristics having means for promoting or enhancing the flow, actively or passively

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Physics & Mathematics (AREA)
  • Fluid Mechanics (AREA)
  • Mechanical Engineering (AREA)
  • General Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Jet Pumps And Other Pumps (AREA)
CN201080058137.2A 2009-12-23 2010-12-23 增强型的喷射器设计 Expired - Fee Related CN102686261B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US28478409P 2009-12-23 2009-12-23
US61/284,784 2009-12-23
PCT/US2010/062084 WO2011079310A1 (en) 2009-12-23 2010-12-23 Enhanced eductor design

Publications (2)

Publication Number Publication Date
CN102686261A CN102686261A (zh) 2012-09-19
CN102686261B true CN102686261B (zh) 2014-09-10

Family

ID=44185936

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201080058137.2A Expired - Fee Related CN102686261B (zh) 2009-12-23 2010-12-23 增强型的喷射器设计

Country Status (9)

Country Link
US (4) US9227030B2 (cg-RX-API-DMAC7.html)
EP (1) EP2515978B1 (cg-RX-API-DMAC7.html)
JP (3) JP5781540B2 (cg-RX-API-DMAC7.html)
CN (1) CN102686261B (cg-RX-API-DMAC7.html)
AU (1) AU2010336338B2 (cg-RX-API-DMAC7.html)
CA (1) CA2781313C (cg-RX-API-DMAC7.html)
IL (3) IL219744A (cg-RX-API-DMAC7.html)
IN (1) IN2012DN04857A (cg-RX-API-DMAC7.html)
WO (1) WO2011079310A1 (cg-RX-API-DMAC7.html)

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CN101389348A (zh) 2006-02-22 2009-03-18 曼金德公司 用于改善包含二酮哌嗪和活性剂的微粒的药物性质的方法
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US8485180B2 (en) 2008-06-13 2013-07-16 Mannkind Corporation Dry powder drug delivery system
CN109568740B (zh) 2008-06-13 2022-05-27 曼金德公司 干粉吸入器和用于药物输送的系统
BR122020002400B1 (pt) 2008-06-20 2021-12-07 Mannkind Corporation Sistema de detecção de inalação de pó seco e sistema de monitoramento acoplável para um inalador de pó seco
US8314106B2 (en) 2008-12-29 2012-11-20 Mannkind Corporation Substituted diketopiperazine analogs for use as drug delivery agents
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US9227030B2 (en) * 2009-12-23 2016-01-05 Map Pharmaceuticals, Inc. Enhanced eductor design
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WO2012174472A1 (en) 2011-06-17 2012-12-20 Mannkind Corporation High capacity diketopiperazine microparticles
HK1201475A1 (en) 2011-10-24 2015-09-04 Mannkind Corporation Methods and compositions for treating pain
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EP3021834A1 (en) 2013-07-18 2016-05-25 MannKind Corporation Heat-stable dry powder pharmaceutical compositions and methods
US10307464B2 (en) 2014-03-28 2019-06-04 Mannkind Corporation Use of ultrarapid acting insulin
CN103877655B (zh) * 2014-04-08 2015-12-30 隋宁昕 自吸固定式吸氧鼻塞
WO2016089981A1 (en) * 2014-12-04 2016-06-09 Carefusion 2200, Inc. Breath-actuated nebulizer for medicine inhalation
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CN109210374B (zh) * 2017-06-30 2021-06-08 北京北方华创微电子装备有限公司 进气管路及半导体加工设备
CA3095939C (en) * 2018-04-06 2023-09-26 Frank Levy Apparatus and method for producing an enriched medical suspension
CN110433366B (zh) * 2019-08-12 2022-03-04 杭州市红十字会医院 一种便携式呼吸科给药器
CN113898570B (zh) * 2021-12-08 2022-02-08 常州萨柏美格医用气体设备有限公司 气体流动过程检测装置及方法、空气压缩机组及检测方法
CN114798201B (zh) * 2022-06-29 2022-10-04 山东沃德净水科技有限公司 一种喷射器优化方法及喷射器
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US20040011357A1 (en) * 2000-07-05 2004-01-22 Philip Braithwaite Actuator comprising moveable membrane
CN101410189A (zh) * 2006-03-27 2009-04-15 贝林格尔英格海姆法玛两合公司 用以施用药物制剂的剂量喷雾器

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US20040011357A1 (en) * 2000-07-05 2004-01-22 Philip Braithwaite Actuator comprising moveable membrane
CN101410189A (zh) * 2006-03-27 2009-04-15 贝林格尔英格海姆法玛两合公司 用以施用药物制剂的剂量喷雾器

Also Published As

Publication number Publication date
IL242205A0 (en) 2015-11-30
US9610415B2 (en) 2017-04-04
AU2010336338A1 (en) 2012-06-21
IL219744A0 (en) 2012-07-31
EP2515978A1 (en) 2012-10-31
IL252847B (en) 2021-02-28
CA2781313A1 (en) 2011-06-30
JP2013515577A (ja) 2013-05-09
JP2017164554A (ja) 2017-09-21
JP5781540B2 (ja) 2015-09-24
EP2515978B1 (en) 2018-02-14
AU2010336338B2 (en) 2015-02-19
IL242205A (en) 2017-07-31
US20170056609A1 (en) 2017-03-02
US20160129208A1 (en) 2016-05-12
CA2781313C (en) 2019-09-17
JP6157542B2 (ja) 2017-07-05
IL252847A0 (en) 2017-08-31
US20110155129A1 (en) 2011-06-30
WO2011079310A1 (en) 2011-06-30
US20200030555A1 (en) 2020-01-30
US9227030B2 (en) 2016-01-05
CN102686261A (zh) 2012-09-19
EP2515978A4 (en) 2015-03-04
IL219744A (en) 2015-11-30
JP2015221225A (ja) 2015-12-10
IN2012DN04857A (cg-RX-API-DMAC7.html) 2015-09-25

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Granted publication date: 20140910