JP5775452B2 - 肝細胞増殖因子（分散因子）活性の低分子モジュレーターの組成物および方法 - Google Patents

肝細胞増殖因子（分散因子）活性の低分子モジュレーターの組成物および方法 Download PDF

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JP5775452B2
JP5775452B2 JP2011517424A JP2011517424A JP5775452B2 JP 5775452 B2 JP5775452 B2 JP 5775452B2 JP 2011517424 A JP2011517424 A JP 2011517424A JP 2011517424 A JP2011517424 A JP 2011517424A JP 5775452 B2 JP5775452 B2 JP 5775452B2
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alkyl
alkoxy
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hydroxy
optionally substituted
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JP2011527675A (ja
JP2011527675A5 (enExample
Inventor
ウェイチョン カイ，
ウェイチョン カイ，
プラカッシュ ナラヤン，
プラカッシュ ナラヤン，
ビジョイ パニッカー，
ビジョイ パニッカー，
デイビッド イー． スミス，
デイビッド イー． スミス，
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Elicio Therapeutics Inc
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Angion Biomedica Corp
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    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
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    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
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JP2011517424A 2008-07-10 2009-07-09 肝細胞増殖因子（分散因子）活性の低分子モジュレーターの組成物および方法 Expired - Fee Related JP5775452B2 (ja)

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US13448508P 2008-07-10 2008-07-10
US61/134,485 2008-07-10
PCT/US2009/004014 WO2010005580A2 (en) 2008-07-10 2009-07-09 Methods and compositions of small molecule modulators of hepatocyte growth factor (scatter factor) activity

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JP2011527675A JP2011527675A (ja) 2011-11-04
JP2011527675A5 JP2011527675A5 (enExample) 2012-08-23
JP5775452B2 true JP5775452B2 (ja) 2015-09-09

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JP2015012415A Pending JP2015108002A (ja) 2008-07-10 2015-01-26 肝細胞増殖因子（分散因子）活性の低分子モジュレーターの組成物および方法

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US (4) US8772326B2 (enExample)
EP (1) EP2313093A4 (enExample)
JP (2) JP5775452B2 (enExample)
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CA (1) CA2767331A1 (enExample)
IL (1) IL210544A (enExample)
WO (1) WO2010005580A2 (enExample)

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JP5775452B2 (ja) 2008-07-10 2015-09-09 アンジオン バイオメディカ コーポレイション 肝細胞増殖因子（分散因子）活性の低分子モジュレーターの組成物および方法
KR20120025524A (ko) 2009-06-12 2012-03-15 스미토모 고무 고교 가부시키가이샤 차량
SG184243A1 (en) 2010-03-30 2012-10-30 Verseon Corp Multisubstituted aromatic compounds as inhibitors of thrombin
CA2813719A1 (en) * 2010-10-05 2012-04-12 Angion Biomedica Corp. Methods of use of small molecule modulators of hepatocyte growth factor (scatter factor) activity
SI2968297T1 (sl) 2013-03-15 2019-02-28 Verseon Corporation Multisubstituirane aromatske skupine kot inhibitorji serinske proteaze
HK1214252A1 (zh) 2013-03-15 2016-07-22 Verseon Corporation 作為凝血酶抑制劑的鹵代吡唑
KR20170048410A (ko) 2014-09-17 2017-05-08 베르선 코포레이션 세린 프로테아제 저해제로서의 피라졸릴-치환된 피리돈 화합물
KR102824411B1 (ko) 2015-02-27 2025-06-23 베르선 코포레이션 세린 프로테아제 저해제로서의 치환된 피라졸 화합물
CN110461316B (zh) * 2016-12-22 2022-09-30 诺贝儿宝贝股份有限公司 (2r，4r)-1，2，4-三羟基十七碳-16-炔在制备预防或治疗肝损伤医药组合物中的应用
EA202192786A1 (ru) 2019-04-11 2022-01-11 Энджион Байомедика Корп. Твердые формы (e)-3-[2-(2-тиенил)винил]-1h-пиразола
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CN102149379A (zh) 2011-08-10
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US20140256727A1 (en) 2014-09-11
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US20190375739A1 (en) 2019-12-12
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