JP5765635B2 - Ku86とその自己抗体との複合体の免疫測定方法、それに用いるキット及びそれを用いた癌判定方法 - Google Patents

Ku86とその自己抗体との複合体の免疫測定方法、それに用いるキット及びそれを用いた癌判定方法 Download PDF

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JP5765635B2
JP5765635B2 JP2011553822A JP2011553822A JP5765635B2 JP 5765635 B2 JP5765635 B2 JP 5765635B2 JP 2011553822 A JP2011553822 A JP 2011553822A JP 2011553822 A JP2011553822 A JP 2011553822A JP 5765635 B2 JP5765635 B2 JP 5765635B2
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complex
cancer
autoantibody
antibody
reagent
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JPWO2011099435A1 (ja
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良 小島
良 小島
健太 野田
健太 野田
正徳 清宮
正徳 清宮
一幸 曽川
一幸 曽川
文夫 野村
文夫 野村
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Nitto Boseki Co Ltd
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Nitto Boseki Co Ltd
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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57484Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/536Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/564Immunoassay; Biospecific binding assay; Materials therefor for pre-existing immune complex or autoimmune disease, i.e. systemic lupus erythematosus, rheumatoid arthritis, multiple sclerosis, rheumatoid factors or complement components C1-C9
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90Enzymes; Proenzymes
    • G01N2333/914Hydrolases (3)
    • G01N2333/916Hydrolases (3) acting on ester bonds (3.1), e.g. phosphatases (3.1.3), phospholipases C or phospholipases D (3.1.4)
    • G01N2333/922Ribonucleases (RNAses); Deoxyribonucleases (DNAses)

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
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  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Oncology (AREA)
  • Hospice & Palliative Care (AREA)
  • Rehabilitation Therapy (AREA)
  • Rheumatology (AREA)
  • Peptides Or Proteins (AREA)
JP2011553822A 2010-02-12 2011-02-07 Ku86とその自己抗体との複合体の免疫測定方法、それに用いるキット及びそれを用いた癌判定方法 Active JP5765635B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2011553822A JP5765635B2 (ja) 2010-02-12 2011-02-07 Ku86とその自己抗体との複合体の免疫測定方法、それに用いるキット及びそれを用いた癌判定方法

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP2010028387 2010-02-12
JP2010028387 2010-02-12
JP2011553822A JP5765635B2 (ja) 2010-02-12 2011-02-07 Ku86とその自己抗体との複合体の免疫測定方法、それに用いるキット及びそれを用いた癌判定方法
PCT/JP2011/052481 WO2011099435A1 (fr) 2010-02-12 2011-02-07 PROCÉDÉ DE MESURE DE L'IMMUNITÉ DU COMPLEXE ASSOCIANT Ku86 ET UN DE SES AUTO-ANTICORPS, NÉCESSAIRE UTILISÉ À CET EFFET ET MÉTHODE DE DIAGNOSTIC DU CANCER L'UTILISANT

Publications (2)

Publication Number Publication Date
JPWO2011099435A1 JPWO2011099435A1 (ja) 2013-06-13
JP5765635B2 true JP5765635B2 (ja) 2015-08-19

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JP2011553822A Active JP5765635B2 (ja) 2010-02-12 2011-02-07 Ku86とその自己抗体との複合体の免疫測定方法、それに用いるキット及びそれを用いた癌判定方法

Country Status (6)

Country Link
US (1) US20120309034A1 (fr)
EP (1) EP2535715B1 (fr)
JP (1) JP5765635B2 (fr)
KR (1) KR101667088B1 (fr)
CN (1) CN102753973B (fr)
WO (1) WO2011099435A1 (fr)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5605375B2 (ja) * 2010-01-25 2014-10-15 日東紡績株式会社 Ku86に対する自己抗体の免疫測定方法、それに用いるキット、及びそれを用いた原発性肝細胞癌の判定方法
KR101465403B1 (ko) * 2014-07-07 2014-11-26 중앙대학교 산학협력단 SET/TAF-Iβ 및 Ku70/80 결합을 이용한 항암제 스크리닝 방법
GB201619954D0 (en) * 2016-11-25 2017-01-11 Oncimmune Ltd Antibody assay
KR102172016B1 (ko) * 2019-02-22 2020-10-30 (주)바이오메트릭스 테크놀로지 항-cyfra21-1 자가항체-항원 결합체 및 cyfra21-1 항원 마커의 검출방법 및 이들 마커의 비율을 이용한 폐암 진단키트

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2011090017A1 (fr) * 2010-01-25 2011-07-28 日東紡績株式会社 Méthode pour l'immunoessai d'un auto-anticorps contre ku86, kit destiné à être utilisé dans celle-ci, et méthode pour la détermination d'un carcinome hépatocellulaire primaire utilisant celle-ci

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9907687D0 (en) * 1999-04-01 1999-05-26 Kudos Pharm Ltd Assays methods and means
JP4486815B2 (ja) * 2001-09-27 2010-06-23 バイオノミックス リミテッド ヒト血管形成遺伝子に対するdna配列
CN100360565C (zh) * 2001-12-22 2008-01-09 4-抗体股份公司 制备脊椎动物淋巴细胞和生产结合蛋白的方法
US20040102404A1 (en) * 2002-11-23 2004-05-27 Isis Pharmaceuticals Inc. Modulation of KU86 expression
KR20060102592A (ko) * 2005-03-24 2006-09-28 바이오제멕스 주식회사 자가항체 검출방법을 이용한 암진단용 면역복합체 및키트와 이를 이용하는 방법
GB0607354D0 (en) * 2006-04-12 2006-05-24 Bioinvent Int Ab Agent, Composition And Method
KR101032607B1 (ko) * 2008-03-14 2011-05-06 심영택 간암 진단용 단백질성 마커

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2011090017A1 (fr) * 2010-01-25 2011-07-28 日東紡績株式会社 Méthode pour l'immunoessai d'un auto-anticorps contre ku86, kit destiné à être utilisé dans celle-ci, et méthode pour la détermination d'un carcinome hépatocellulaire primaire utilisant celle-ci
JP5605375B2 (ja) * 2010-01-25 2014-10-15 日東紡績株式会社 Ku86に対する自己抗体の免疫測定方法、それに用いるキット、及びそれを用いた原発性肝細胞癌の判定方法

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
JPN6014001409; Yaneva M, Arnett FC: 'Antibodies against Ku protein in sera frompatients with autoimmune diseases' Clin Exp Immunol 76(3), 198906, 366-372 *

Also Published As

Publication number Publication date
CN102753973A (zh) 2012-10-24
KR20120115537A (ko) 2012-10-18
WO2011099435A1 (fr) 2011-08-18
EP2535715B1 (fr) 2017-09-13
EP2535715A1 (fr) 2012-12-19
EP2535715A4 (fr) 2013-06-19
CN102753973B (zh) 2015-09-09
JPWO2011099435A1 (ja) 2013-06-13
KR101667088B1 (ko) 2016-10-17
US20120309034A1 (en) 2012-12-06

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