JP5762738B2 - 細胞株、黒色腫の治療のためにそれを含む組成物、組成物の製造手順および治療方法 - Google Patents
細胞株、黒色腫の治療のためにそれを含む組成物、組成物の製造手順および治療方法 Download PDFInfo
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- JP5762738B2 JP5762738B2 JP2010502629A JP2010502629A JP5762738B2 JP 5762738 B2 JP5762738 B2 JP 5762738B2 JP 2010502629 A JP2010502629 A JP 2010502629A JP 2010502629 A JP2010502629 A JP 2010502629A JP 5762738 B2 JP5762738 B2 JP 5762738B2
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
- A61K39/0011—Cancer antigens
- A61K39/00119—Melanoma antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K40/00—Cellular immunotherapy
- A61K40/10—Cellular immunotherapy characterised by the cell type used
- A61K40/19—Dendritic cells
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K40/00—Cellular immunotherapy
- A61K40/20—Cellular immunotherapy characterised by the effect or the function of the cells
- A61K40/24—Antigen-presenting cells [APC]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K40/00—Cellular immunotherapy
- A61K40/40—Cellular immunotherapy characterised by antigens that are targeted or presented by cells of the immune system
- A61K40/41—Vertebrate antigens
- A61K40/42—Cancer antigens
- A61K40/4271—Melanoma antigens
- A61K40/4272—Melan-A/MART
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K40/00—Cellular immunotherapy
- A61K40/40—Cellular immunotherapy characterised by antigens that are targeted or presented by cells of the immune system
- A61K40/41—Vertebrate antigens
- A61K40/42—Cancer antigens
- A61K40/4271—Melanoma antigens
- A61K40/4273—Glycoprotein 100 [Gp100]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N13/00—Treatment of microorganisms or enzymes with electrical or wave energy, e.g. magnetism, sonic waves
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/515—Animal cells
- A61K2039/5152—Tumor cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/515—Animal cells
- A61K2039/5154—Antigen presenting cells [APCs], e.g. dendritic cells or macrophages
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/80—Vaccine for a specifically defined cancer
- A61K2039/876—Skin, melanoma
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2239/00—Indexing codes associated with cellular immunotherapy of group A61K40/00
- A61K2239/31—Indexing codes associated with cellular immunotherapy of group A61K40/00 characterized by the route of administration
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Genetics & Genomics (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- Immunology (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Dermatology (AREA)
- Mycology (AREA)
- Oncology (AREA)
- Cell Biology (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ARP20070101520 | 2007-04-11 | ||
| ARP070101520A AR060424A1 (es) | 2007-04-11 | 2007-04-11 | Lineas celulares , composiciones para el tratamiento de melanomas que las comprenden procedimientos para preparar las composiciones y metodos de tratamiento |
| PCT/IB2008/051385 WO2008126039A2 (en) | 2007-04-11 | 2008-04-11 | Cell lines, compositions comprising them for the treatment of melanomas, procedures to prepare the compositions, and treatment methods |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2010523141A JP2010523141A (ja) | 2010-07-15 |
| JP2010523141A5 JP2010523141A5 (cg-RX-API-DMAC7.html) | 2011-05-26 |
| JP5762738B2 true JP5762738B2 (ja) | 2015-08-12 |
Family
ID=39590605
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010502629A Active JP5762738B2 (ja) | 2007-04-11 | 2008-04-11 | 細胞株、黒色腫の治療のためにそれを含む組成物、組成物の製造手順および治療方法 |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US8501168B2 (cg-RX-API-DMAC7.html) |
| EP (1) | EP2146742B1 (cg-RX-API-DMAC7.html) |
| JP (1) | JP5762738B2 (cg-RX-API-DMAC7.html) |
| KR (1) | KR101502518B1 (cg-RX-API-DMAC7.html) |
| CN (1) | CN101861163B (cg-RX-API-DMAC7.html) |
| AR (1) | AR060424A1 (cg-RX-API-DMAC7.html) |
| AU (1) | AU2008238909B2 (cg-RX-API-DMAC7.html) |
| BR (1) | BRPI0809767B1 (cg-RX-API-DMAC7.html) |
| CA (1) | CA2683629C (cg-RX-API-DMAC7.html) |
| CO (1) | CO6260100A2 (cg-RX-API-DMAC7.html) |
| DK (1) | DK2146742T3 (cg-RX-API-DMAC7.html) |
| ES (1) | ES2390130T3 (cg-RX-API-DMAC7.html) |
| MX (1) | MX2009010927A (cg-RX-API-DMAC7.html) |
| NZ (1) | NZ580533A (cg-RX-API-DMAC7.html) |
| RU (1) | RU2484134C2 (cg-RX-API-DMAC7.html) |
| WO (1) | WO2008126039A2 (cg-RX-API-DMAC7.html) |
| ZA (1) | ZA200907240B (cg-RX-API-DMAC7.html) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP6077735B2 (ja) * | 2011-06-08 | 2017-02-08 | 日本電子株式会社 | 電子顕微鏡観察用染色剤および電子顕微鏡観察用試料の染色方法 |
| SG11201401631VA (en) | 2011-10-20 | 2014-05-29 | California Stem Cell Inc | Antigen presenting cancer vaccine with gamma interferon |
| JP6077757B2 (ja) * | 2012-04-17 | 2017-02-08 | 日本電子株式会社 | 電子顕微鏡観察用染色剤および電子顕微鏡観察用試料の染色方法 |
| JP5921386B2 (ja) * | 2012-08-27 | 2016-05-24 | 日本電子株式会社 | 電子顕微鏡観察用染色剤および電子顕微鏡観察用試料の染色方法 |
| CN103146641B (zh) * | 2013-02-06 | 2015-03-25 | 云南中科灵长类生物医学重点实验室 | 多能干细胞的传代方法及其用途 |
| CN104990781B (zh) * | 2015-06-29 | 2018-02-16 | 中国医学科学院皮肤病研究所 | 黑素细胞免疫组化苏木素—甲苯胺蓝双重复染法 |
| AU2020395765A1 (en) | 2019-12-03 | 2022-06-16 | Neuvogen, Inc. | Tumor cell vaccines |
| RU2755233C1 (ru) * | 2021-01-11 | 2021-09-14 | Сергей Анатольевич Яргунин | Способ лечения меланомы кожи IIb-IIc стадий |
| CN115074328B (zh) * | 2022-06-21 | 2025-02-07 | 中国人民解放军空军军医大学 | 一种用于治疗黑素瘤的细胞株及其多效价全细胞疫苗与使用方法 |
| WO2025224605A1 (en) | 2024-04-23 | 2025-10-30 | Consejo Nacional De Investigaciones Científicas Y Técnicas (Conicet) | Sequential administration of anti-melanoma vaccine and anti-pd-1 monoclonal antibodies |
Family Cites Families (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5882654A (en) * | 1989-11-03 | 1999-03-16 | Morton; Donald L. | Polyvalent melanoma vaccine |
| KR20000022445A (ko) * | 1996-07-10 | 2000-04-25 | 크리스토퍼 엘. 와이트, 스코트 지. 홀퀴스트, 스티븐 엘. 말라스카 | 수상돌기 세포의 활성화 방법 |
| AU3889997A (en) * | 1996-08-16 | 1998-03-06 | Johns Hopkins University School Of Medicine, The | Melanoma cell lines expressing shared immunodominant melanoma antigens nd methods of using same |
| WO1999042564A2 (en) * | 1998-02-20 | 1999-08-26 | The Rockefeller University | Apoptotic cell-mediated antigen presentation to dendritic cells |
| US7988963B1 (en) * | 1999-10-15 | 2011-08-02 | Baylor Research Institute | Use of allogeneic cell lines to load antigen presenting cells to elicit or eliminate immune responses |
| WO2001028583A2 (en) * | 1999-10-18 | 2001-04-26 | St. Vincent's Hospital And Medical Center Of New York | Melanoma vaccine and methods of making and using same |
| US7015205B1 (en) * | 1999-10-18 | 2006-03-21 | St. Vincent's Hospital And Medical Center Of New York | Melanoma vaccine and methods of making and using same |
| WO2001048154A1 (en) * | 1999-12-28 | 2001-07-05 | Toyoshima, Kumao | Maturation-promoting agent for immature dendritic cells |
| EP1326961B1 (en) * | 2000-09-15 | 2007-08-22 | Ortho-McNeil Pharmaceutical, Inc. | Compositions and methods for inducing specific cytolytic t cell responses |
| US20030072737A1 (en) * | 2000-12-29 | 2003-04-17 | Michael Brines | Tissue protective cytokines for the protection, restoration, and enhancement of responsive cells, tissues and organs |
| IL140796A0 (en) * | 2001-01-08 | 2002-02-10 | Hadasit Med Res Service | An autologous anti-cancer vaccine |
| CA2440229A1 (en) * | 2001-03-09 | 2002-09-19 | Baylor Research Institute | Method of treating malignancies through induction of blood immune responses |
| US7354909B2 (en) * | 2001-08-14 | 2008-04-08 | The United States Of America As Represented By Secretary Of The Department Of Health And Human Services | Method for rapid generation of mature dendritic cells |
| EP1451305A4 (en) * | 2001-11-07 | 2005-10-05 | Mannkind Corp | EPITOPE SYNCHRONIZATION IN CELLS THAT HAVE ANTIGENS |
| CN102600461B (zh) * | 2002-12-06 | 2017-07-14 | 西北生物治疗药物公司 | 给予体外部分成熟的树突细胞治疗肿瘤 |
| EP1623011B1 (en) * | 2003-05-09 | 2013-01-02 | Janssen Biotech, Inc. | Il-23p40 specific immunoglobulin derived proteins, compositions, methods and uses |
| JP5021309B2 (ja) * | 2003-10-16 | 2012-09-05 | ステファン ジョン ラルフ | 免疫調節性組成物およびその使用方法 |
| RU2262941C2 (ru) | 2004-01-05 | 2005-10-27 | Государственное учреждение Научно-исследовательский институт клинической иммунологии СО РАМН | Способ иммунотерапии злокачественных опухолей головного мозга |
| EP1740946B1 (en) * | 2004-04-20 | 2013-11-06 | Genmab A/S | Human monoclonal antibodies against cd20 |
| CA2565874C (en) * | 2004-05-10 | 2017-10-03 | Macrogenics, Inc. | Humanized fc.gamma.riib-specific antibodies and methods of use thereof |
| RU2283129C1 (ru) | 2004-12-24 | 2006-09-10 | Сергей Викторович Луценко | Белковопептидный противоопухолевый композит, клеточный препарат, активированный этим композитом, и способ профилактики или лечения опухолей |
-
2007
- 2007-04-11 AR ARP070101520A patent/AR060424A1/es active IP Right Grant
-
2008
- 2008-04-11 US US12/450,721 patent/US8501168B2/en active Active
- 2008-04-11 ES ES08737810T patent/ES2390130T3/es active Active
- 2008-04-11 WO PCT/IB2008/051385 patent/WO2008126039A2/en not_active Ceased
- 2008-04-11 CA CA2683629A patent/CA2683629C/en active Active
- 2008-04-11 MX MX2009010927A patent/MX2009010927A/es active IP Right Grant
- 2008-04-11 JP JP2010502629A patent/JP5762738B2/ja active Active
- 2008-04-11 KR KR1020097022846A patent/KR101502518B1/ko active Active
- 2008-04-11 NZ NZ580533A patent/NZ580533A/xx unknown
- 2008-04-11 RU RU2009141593/10A patent/RU2484134C2/ru active
- 2008-04-11 AU AU2008238909A patent/AU2008238909B2/en active Active
- 2008-04-11 EP EP08737810A patent/EP2146742B1/en active Active
- 2008-04-11 DK DK08737810.5T patent/DK2146742T3/da active
- 2008-04-11 BR BRPI0809767-4A patent/BRPI0809767B1/pt active IP Right Grant
- 2008-04-11 CN CN2008800182498A patent/CN101861163B/zh active Active
-
2009
- 2009-10-16 ZA ZA200907240A patent/ZA200907240B/xx unknown
- 2009-10-28 CO CO09121156A patent/CO6260100A2/es active IP Right Grant
Also Published As
| Publication number | Publication date |
|---|---|
| KR101502518B1 (ko) | 2015-03-13 |
| US20100183683A1 (en) | 2010-07-22 |
| MX2009010927A (es) | 2010-02-11 |
| WO2008126039A3 (en) | 2008-12-11 |
| CA2683629A1 (en) | 2008-10-23 |
| EP2146742B1 (en) | 2012-07-11 |
| JP2010523141A (ja) | 2010-07-15 |
| RU2484134C2 (ru) | 2013-06-10 |
| ES2390130T3 (es) | 2012-11-06 |
| BRPI0809767A2 (pt) | 2014-09-23 |
| AR060424A1 (es) | 2008-06-18 |
| US8501168B2 (en) | 2013-08-06 |
| ZA200907240B (en) | 2010-07-28 |
| BRPI0809767B1 (pt) | 2022-04-12 |
| WO2008126039A2 (en) | 2008-10-23 |
| CN101861163A (zh) | 2010-10-13 |
| RU2009141593A (ru) | 2011-05-20 |
| NZ580533A (en) | 2012-08-31 |
| CO6260100A2 (es) | 2011-03-22 |
| CN101861163B (zh) | 2013-06-12 |
| AU2008238909A1 (en) | 2008-10-23 |
| CA2683629C (en) | 2016-06-21 |
| DK2146742T3 (da) | 2012-10-22 |
| KR20090129501A (ko) | 2009-12-16 |
| EP2146742A2 (en) | 2010-01-27 |
| AU2008238909B2 (en) | 2013-11-07 |
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