JP5750373B2 - 慢性炎症性応答の調節および自己免疫疾患の処置のためのil−4由来ペプチド - Google Patents
慢性炎症性応答の調節および自己免疫疾患の処置のためのil−4由来ペプチド Download PDFInfo
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- JP5750373B2 JP5750373B2 JP2011535880A JP2011535880A JP5750373B2 JP 5750373 B2 JP5750373 B2 JP 5750373B2 JP 2011535880 A JP2011535880 A JP 2011535880A JP 2011535880 A JP2011535880 A JP 2011535880A JP 5750373 B2 JP5750373 B2 JP 5750373B2
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/54—Interleukins [IL]
- C07K14/5406—IL-4
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P11/06—Antiasthmatics
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A—HUMAN NECESSITIES
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- A61P13/10—Drugs for disorders of the urinary system of the bladder
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
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- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
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- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P37/02—Immunomodulators
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P5/14—Drugs for disorders of the endocrine system of the thyroid hormones, e.g. T3, T4
- A61P5/16—Drugs for disorders of the endocrine system of the thyroid hormones, e.g. T3, T4 for decreasing, blocking or antagonising the activity of the thyroid hormones
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Neurology (AREA)
- Immunology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Diabetes (AREA)
- Urology & Nephrology (AREA)
- Pulmonology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Gastroenterology & Hepatology (AREA)
- Molecular Biology (AREA)
- Endocrinology (AREA)
- Toxicology (AREA)
- Hematology (AREA)
- Reproductive Health (AREA)
- Virology (AREA)
- Cardiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Heart & Thoracic Surgery (AREA)
- Psychiatry (AREA)
- Psychology (AREA)
- Zoology (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DKPA200801601 | 2008-11-17 | ||
| DKPA200801601 | 2008-11-17 | ||
| PCT/DK2009/050304 WO2010054667A1 (en) | 2008-11-17 | 2009-11-17 | Il-4-derived peptides for modulation of the chronic inflammatory response and treatment of autoimmune diseases |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2012508698A JP2012508698A (ja) | 2012-04-12 |
| JP2012508698A5 JP2012508698A5 (enExample) | 2012-12-13 |
| JP5750373B2 true JP5750373B2 (ja) | 2015-07-22 |
Family
ID=41510516
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011535880A Active JP5750373B2 (ja) | 2008-11-17 | 2009-11-17 | 慢性炎症性応答の調節および自己免疫疾患の処置のためのil−4由来ペプチド |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US8546321B2 (enExample) |
| EP (1) | EP2365983B1 (enExample) |
| JP (1) | JP5750373B2 (enExample) |
| CN (1) | CN102216323B (enExample) |
| AU (1) | AU2009316076B2 (enExample) |
| BR (1) | BRPI0921717A2 (enExample) |
| CA (1) | CA2743394C (enExample) |
| ES (1) | ES2620437T3 (enExample) |
| IL (1) | IL212962A0 (enExample) |
| NZ (1) | NZ592943A (enExample) |
| RU (1) | RU2542375C2 (enExample) |
| WO (1) | WO2010054667A1 (enExample) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| LT2665486T (lt) | 2011-01-18 | 2020-04-10 | Bioniz, Llc | Kompozicijos, skirtos gama-c-citokino aktyvumui moduliuoti |
| US9959384B2 (en) | 2013-12-10 | 2018-05-01 | Bioniz, Llc | Methods of developing selective peptide antagonists |
| CN107683291B (zh) | 2015-04-02 | 2021-11-19 | 英特维特国际股份有限公司 | 针对犬白介素-4受体α的抗体 |
| HUE056544T2 (hu) | 2015-10-09 | 2022-02-28 | Bioniz Llc | Gamma-C-citokin aktivitás modulálása |
| CA3054820A1 (en) * | 2017-04-07 | 2018-10-11 | Bioniz, Llc | Stable modulators of gamma-c-cytokine activity |
| KR102095284B1 (ko) * | 2017-05-11 | 2020-04-01 | (주)케어젠 | 메토트렉세이트와 펩타이드의 결합체 |
| EP3530320B1 (en) | 2018-02-27 | 2023-11-15 | Universitätsmedizin der Johannes Gutenberg-Universität Mainz | Novel il-4-/il-13-derived peptide compounds for the treatment or prevention of neurodegenerative or neuroinflammatory diseases |
| CN111494625B (zh) * | 2018-12-25 | 2022-06-21 | 江苏荃信生物医药股份有限公司 | 用于治疗il-4和/或il-13介导的信号转导相关的疾病的药物组合物 |
| CN113874075A (zh) | 2019-05-03 | 2021-12-31 | 比奥尼斯有限责任公司 | 调节γC-细胞因子信号传导对于治疗脱发和脱发相关病症的影响 |
| CA3242457A1 (en) | 2022-01-05 | 2023-07-13 | Serodus Aps | Il-4 derived peptides for use in the treatment of obesity |
| JP7634138B1 (ja) | 2022-04-29 | 2025-02-20 | セロダス アンパーツセルスケープ | 糖尿病性腎症の治療における使用のためのil-4由来ペプチド断片 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH05503088A (ja) * | 1989-11-21 | 1993-05-27 | ザ ユニバーシティー オブ メルボルン | 抗炎症用の組成物及び方法 |
| AU639754B2 (en) | 1989-12-20 | 1993-08-05 | Schering Corporation | Antibody antagonists of human interleukin-4 |
| US6337072B1 (en) * | 1998-04-03 | 2002-01-08 | Hyseq, Inc. | Interleukin-1 receptor antagonist and recombinant production thereof |
| KR100704140B1 (ko) * | 1999-02-12 | 2007-04-09 | 더 스크립스 리서치 인스티튜트 | 혈관형성 억제제 및 항-종양 면역요법제를 포함하는, 종양 및 전이를 치료하기 위한 약제학적 조성물 및 이를 포함하는 키트 |
| GB9912350D0 (en) * | 1999-05-26 | 1999-07-28 | European Molecular Biology Lab Embl | Modified cytokine |
| US20030056244A1 (en) * | 2000-05-02 | 2003-03-20 | Ning Huang | Feed additive compositions and methods |
| FR2838444B1 (fr) * | 2002-04-10 | 2016-01-01 | Neovacs | Nouveaux peptides et leur application en therapeutique |
| WO2004096849A2 (en) * | 2003-04-25 | 2004-11-11 | University Of Manitoba | Peptide-based cytokine/chemokine vaccines against allergy |
| WO2005040202A2 (en) * | 2003-10-16 | 2005-05-06 | Aplagen Gmbh | Stabilized alpha-helical peptides |
-
2009
- 2009-11-17 AU AU2009316076A patent/AU2009316076B2/en not_active Ceased
- 2009-11-17 CN CN200980145907.4A patent/CN102216323B/zh not_active Expired - Fee Related
- 2009-11-17 CA CA2743394A patent/CA2743394C/en active Active
- 2009-11-17 ES ES09764175.7T patent/ES2620437T3/es active Active
- 2009-11-17 EP EP09764175.7A patent/EP2365983B1/en active Active
- 2009-11-17 WO PCT/DK2009/050304 patent/WO2010054667A1/en not_active Ceased
- 2009-11-17 US US13/127,574 patent/US8546321B2/en active Active
- 2009-11-17 JP JP2011535880A patent/JP5750373B2/ja active Active
- 2009-11-17 NZ NZ592943A patent/NZ592943A/xx not_active IP Right Cessation
- 2009-11-17 BR BRPI0921717A patent/BRPI0921717A2/pt not_active IP Right Cessation
- 2009-11-17 RU RU2011121971/10A patent/RU2542375C2/ru not_active IP Right Cessation
-
2011
- 2011-05-17 IL IL212962A patent/IL212962A0/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP2365983A1 (en) | 2011-09-21 |
| AU2009316076A1 (en) | 2010-05-20 |
| RU2542375C2 (ru) | 2015-02-20 |
| IL212962A0 (en) | 2011-07-31 |
| AU2009316076B2 (en) | 2015-11-19 |
| ES2620437T3 (es) | 2017-06-28 |
| US20110300148A1 (en) | 2011-12-08 |
| WO2010054667A1 (en) | 2010-05-20 |
| US8546321B2 (en) | 2013-10-01 |
| BRPI0921717A2 (pt) | 2018-10-09 |
| RU2011121971A (ru) | 2012-12-27 |
| JP2012508698A (ja) | 2012-04-12 |
| CN102216323B (zh) | 2016-08-03 |
| EP2365983B1 (en) | 2016-12-28 |
| CN102216323A (zh) | 2011-10-12 |
| NZ592943A (en) | 2012-09-28 |
| CA2743394C (en) | 2018-01-02 |
| CA2743394A1 (en) | 2010-05-20 |
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