JP5721909B2 - 貼付補助具 - Google Patents
貼付補助具 Download PDFInfo
- Publication number
- JP5721909B2 JP5721909B2 JP2014523341A JP2014523341A JP5721909B2 JP 5721909 B2 JP5721909 B2 JP 5721909B2 JP 2014523341 A JP2014523341 A JP 2014523341A JP 2014523341 A JP2014523341 A JP 2014523341A JP 5721909 B2 JP5721909 B2 JP 5721909B2
- Authority
- JP
- Japan
- Prior art keywords
- protective film
- film portion
- adhesive
- active ingredient
- skin
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- 230000001681 protective effect Effects 0.000 claims description 177
- 239000004480 active ingredient Substances 0.000 claims description 40
- 239000000463 material Substances 0.000 claims description 25
- 238000000576 coating method Methods 0.000 claims description 19
- 239000011248 coating agent Substances 0.000 claims description 14
- 239000000853 adhesive Substances 0.000 description 36
- 230000001070 adhesive effect Effects 0.000 description 35
- 230000001225 therapeutic effect Effects 0.000 description 35
- 239000011159 matrix material Substances 0.000 description 15
- 239000004820 Pressure-sensitive adhesive Substances 0.000 description 12
- 238000000926 separation method Methods 0.000 description 11
- 239000010410 layer Substances 0.000 description 10
- 230000000704 physical effect Effects 0.000 description 8
- 239000004821 Contact adhesive Substances 0.000 description 7
- 238000000034 method Methods 0.000 description 6
- 229920001296 polysiloxane Polymers 0.000 description 6
- -1 alkyl methacrylates Chemical class 0.000 description 5
- 229920006267 polyester film Polymers 0.000 description 5
- 229920001577 copolymer Polymers 0.000 description 4
- 238000006243 chemical reaction Methods 0.000 description 3
- 238000011109 contamination Methods 0.000 description 3
- 239000004811 fluoropolymer Substances 0.000 description 3
- 229920002313 fluoropolymer Polymers 0.000 description 3
- 238000005259 measurement Methods 0.000 description 3
- 239000012528 membrane Substances 0.000 description 3
- 239000012790 adhesive layer Substances 0.000 description 2
- 238000005452 bending Methods 0.000 description 2
- 230000015572 biosynthetic process Effects 0.000 description 2
- 239000011247 coating layer Substances 0.000 description 2
- 150000001875 compounds Chemical class 0.000 description 2
- 239000007788 liquid Substances 0.000 description 2
- 229920000642 polymer Polymers 0.000 description 2
- 239000007787 solid Substances 0.000 description 2
- 238000001179 sorption measurement Methods 0.000 description 2
- 238000009736 wetting Methods 0.000 description 2
- SMZOUWXMTYCWNB-UHFFFAOYSA-N 2-(2-methoxy-5-methylphenyl)ethanamine Chemical compound COC1=CC=C(C)C=C1CCN SMZOUWXMTYCWNB-UHFFFAOYSA-N 0.000 description 1
- NIXOWILDQLNWCW-UHFFFAOYSA-N 2-Propenoic acid Natural products OC(=O)C=C NIXOWILDQLNWCW-UHFFFAOYSA-N 0.000 description 1
- WHNPOQXWAMXPTA-UHFFFAOYSA-N 3-methylbut-2-enamide Chemical compound CC(C)=CC(N)=O WHNPOQXWAMXPTA-UHFFFAOYSA-N 0.000 description 1
- HRPVXLWXLXDGHG-UHFFFAOYSA-N Acrylamide Chemical compound NC(=O)C=C HRPVXLWXLXDGHG-UHFFFAOYSA-N 0.000 description 1
- NIXOWILDQLNWCW-UHFFFAOYSA-M Acrylate Chemical compound [O-]C(=O)C=C NIXOWILDQLNWCW-UHFFFAOYSA-M 0.000 description 1
- NLHHRLWOUZZQLW-UHFFFAOYSA-N Acrylonitrile Chemical compound C=CC#N NLHHRLWOUZZQLW-UHFFFAOYSA-N 0.000 description 1
- 229920002799 BoPET Polymers 0.000 description 1
- CERQOIWHTDAKMF-UHFFFAOYSA-N Methacrylic acid Chemical compound CC(=C)C(O)=O CERQOIWHTDAKMF-UHFFFAOYSA-N 0.000 description 1
- 239000004698 Polyethylene Substances 0.000 description 1
- 229920002367 Polyisobutene Polymers 0.000 description 1
- 239000004743 Polypropylene Substances 0.000 description 1
- XTXRWKRVRITETP-UHFFFAOYSA-N Vinyl acetate Chemical compound CC(=O)OC=C XTXRWKRVRITETP-UHFFFAOYSA-N 0.000 description 1
- 125000005250 alkyl acrylate group Chemical group 0.000 description 1
- 210000004204 blood vessel Anatomy 0.000 description 1
- FACXGONDLDSNOE-UHFFFAOYSA-N buta-1,3-diene;styrene Chemical compound C=CC=C.C=CC1=CC=CC=C1.C=CC1=CC=CC=C1 FACXGONDLDSNOE-UHFFFAOYSA-N 0.000 description 1
- 230000000295 complement effect Effects 0.000 description 1
- 238000007796 conventional method Methods 0.000 description 1
- 230000032798 delamination Effects 0.000 description 1
- 230000001419 dependent effect Effects 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 238000009792 diffusion process Methods 0.000 description 1
- 229920001971 elastomer Polymers 0.000 description 1
- 238000004049 embossing Methods 0.000 description 1
- 238000011067 equilibration Methods 0.000 description 1
- 229920001903 high density polyethylene Polymers 0.000 description 1
- 239000004700 high-density polyethylene Substances 0.000 description 1
- 229920001519 homopolymer Polymers 0.000 description 1
- 238000007373 indentation Methods 0.000 description 1
- 238000007562 laser obscuration time method Methods 0.000 description 1
- 239000000178 monomer Substances 0.000 description 1
- 230000007659 motor function Effects 0.000 description 1
- RCLLINSDAJVOHP-UHFFFAOYSA-N n-ethyl-n',n'-dimethylprop-2-enehydrazide Chemical compound CCN(N(C)C)C(=O)C=C RCLLINSDAJVOHP-UHFFFAOYSA-N 0.000 description 1
- 239000012466 permeate Substances 0.000 description 1
- 239000011505 plaster Substances 0.000 description 1
- 229920000728 polyester Polymers 0.000 description 1
- 229920000573 polyethylene Polymers 0.000 description 1
- 229920000139 polyethylene terephthalate Polymers 0.000 description 1
- 239000005020 polyethylene terephthalate Substances 0.000 description 1
- 229920001195 polyisoprene Polymers 0.000 description 1
- 229920001155 polypropylene Polymers 0.000 description 1
- 239000004814 polyurethane Substances 0.000 description 1
- 229920002635 polyurethane Polymers 0.000 description 1
- 229920000915 polyvinyl chloride Polymers 0.000 description 1
- 239000004800 polyvinyl chloride Substances 0.000 description 1
- 229920001289 polyvinyl ether Polymers 0.000 description 1
- 230000001105 regulatory effect Effects 0.000 description 1
- 239000005060 rubber Substances 0.000 description 1
- 229920003048 styrene butadiene rubber Polymers 0.000 description 1
- 229920000468 styrene butadiene styrene block copolymer Polymers 0.000 description 1
- 239000000758 substrate Substances 0.000 description 1
- 230000003746 surface roughness Effects 0.000 description 1
- 238000010998 test method Methods 0.000 description 1
Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
- A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
- A61K9/7084—Transdermal patches having a drug layer or reservoir, and one or more separate drug-free skin-adhesive layers, e.g. between drug reservoir and skin, or surrounding the drug reservoir; Liquid-filled reservoir patches
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
- A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Dermatology (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Media Introduction/Drainage Providing Device (AREA)
Description
Claims (2)
- 少なくとも1種類の活性成分を含む少なくとも1つの活性成分貯留部(11)と、
皮膚への貼付のために設計され、表面の少なくともいくつかの部分が粘着性である貼付面と、
該貼付面から離れた前記活性成分貯留部(11)の後面を被覆する裏打ち層(12)と、
前記貼付面の皮膚に貼付する側を被覆し、第1の保護フィルム部分(14a)及び第2の保護フィルム部分(14b)からなる保護フィルム部分(14)とからなり、
前記第1の保護フィルム部分(14a)の厚さが、前記第2の保護フィルム部分(14b)の厚さと異なり、
前記第2の保護フィルム部分(14b)の端部が、前記第1の保護フィルム部分(14a)によって被覆され、2層の保護フィルムを形成するか、又は
前記第1の保護フィルム部分(14a)の端部と、前記第2の保護フィルム部分(14b)の端部とが、互いに隣接することを特徴とする経皮治療システム。 - 少なくとも1種類の活性成分を含む少なくとも1つの活性成分貯留部(11)と、
皮膚への貼付のために設計され、表面の少なくともいくつかの部分が粘着性である貼付面と、
該貼付面から離れた前記活性成分貯留部(11)の後面を被覆する裏打ち層(12)と、
前記貼付面の皮膚に貼付する側を被覆し、第1の保護フィルム部分(14a)及び第2の保護フィルム部分(14b)からなる保護フィルム部分(14)とからなり、
前記第1の保護フィルム部分(14a)が、前記第2の保護フィルム部分(14b)とは異なる材料から形成され、
前記第2の保護フィルム部分(14b)の端部が、前記第1の保護フィルム部分(14a)によって被覆され、2層の保護フィルムを形成するか、又は
前記第1の保護フィルム部分(14a)の端部と、前記第2の保護フィルム部分(14b)の端部とが、互いに隣接することを特徴とする経皮治療システム。
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE102011080390A DE102011080390B3 (de) | 2011-08-03 | 2011-08-03 | Applikationshilfe |
DE102011080390.4 | 2011-08-03 | ||
PCT/EP2012/065264 WO2013017689A1 (de) | 2011-08-03 | 2012-08-03 | Applikationshilfe |
Publications (2)
Publication Number | Publication Date |
---|---|
JP2014521681A JP2014521681A (ja) | 2014-08-28 |
JP5721909B2 true JP5721909B2 (ja) | 2015-05-20 |
Family
ID=46509781
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2014523341A Active JP5721909B2 (ja) | 2011-08-03 | 2012-08-03 | 貼付補助具 |
Country Status (7)
Country | Link |
---|---|
US (1) | US9439873B2 (ja) |
EP (1) | EP2739273A1 (ja) |
JP (1) | JP5721909B2 (ja) |
KR (1) | KR101572398B1 (ja) |
DE (1) | DE102011080390B3 (ja) |
EA (1) | EA201490390A1 (ja) |
WO (1) | WO2013017689A1 (ja) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN105873573B (zh) | 2013-12-31 | 2020-11-24 | 强生消费者公司 | 形成成型膜产品的方法 |
KR102240525B1 (ko) * | 2013-12-31 | 2021-04-16 | 존슨 앤드 존슨 컨수머 인코포레이티드 | 다층의 형상화된 필름을 형성하기 위한 방법 |
JP2017164191A (ja) * | 2016-03-15 | 2017-09-21 | 凸版印刷株式会社 | 経皮投与デバイス |
Family Cites Families (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE68901510D1 (de) | 1988-08-11 | 1992-06-17 | Nitto Denko Corp | Heftverbandsbahn. |
US5958447A (en) * | 1998-03-17 | 1999-09-28 | Plc Holding, L.L.C. | Adhesive matrix type transdermal patch and method of manufacturing same |
US6129929A (en) * | 1998-10-30 | 2000-10-10 | Noven Pharmaceuticals, Inc. | Patch applicator |
CN1331586A (zh) * | 1998-12-18 | 2002-01-16 | 阿尔扎有限公司 | 透明的透皮烟碱输送装置 |
DE19925338A1 (de) | 1999-06-02 | 2000-12-07 | Lohmann Therapie Syst Lts | Substratabschnitte mit erhöhter Lagerstabilität während ihrer Lagerung in Beutelverpackung, sowie Verfahren zu ihrer Herstellung |
DE10141651B4 (de) * | 2001-08-24 | 2007-02-15 | Lts Lohmann Therapie-Systeme Ag | Transdermales Therapeutisches System (TTS) mit dem Wirkstoff Fentanyl und Verfahren zu seiner Herstellung |
US8524272B2 (en) * | 2003-08-15 | 2013-09-03 | Mylan Technologies, Inc. | Transdermal patch incorporating active agent migration barrier layer |
US7880051B2 (en) * | 2003-11-28 | 2011-02-01 | Coloplast A/S | Dressing product |
JP5010829B2 (ja) * | 2005-12-28 | 2012-08-29 | 帝國製薬株式会社 | 貼付剤 |
JP4769575B2 (ja) * | 2005-12-28 | 2011-09-07 | 帝國製薬株式会社 | 貼付剤及びその製造方法 |
JP5546092B2 (ja) * | 2006-12-26 | 2014-07-09 | 帝國製薬株式会社 | 貼付剤の製造方法 |
JP2010163367A (ja) | 2009-01-13 | 2010-07-29 | Nitto Denko Corp | 貼付剤および貼付製剤 |
DE102010000661A1 (de) * | 2010-01-04 | 2011-07-07 | Acino Ag, 83714 | Verfahren und Vorrichtung zur Herstellung einer überlappenden Schutzfolie für ein transdermales therapeutisches System |
-
2011
- 2011-08-03 DE DE102011080390A patent/DE102011080390B3/de active Active
-
2012
- 2012-08-03 WO PCT/EP2012/065264 patent/WO2013017689A1/de active Application Filing
- 2012-08-03 EP EP12745829.7A patent/EP2739273A1/de not_active Withdrawn
- 2012-08-03 KR KR1020147005719A patent/KR101572398B1/ko active IP Right Grant
- 2012-08-03 JP JP2014523341A patent/JP5721909B2/ja active Active
- 2012-08-03 US US14/236,415 patent/US9439873B2/en active Active
- 2012-08-03 EA EA201490390A patent/EA201490390A1/ru unknown
Also Published As
Publication number | Publication date |
---|---|
US9439873B2 (en) | 2016-09-13 |
KR101572398B1 (ko) | 2015-11-26 |
EA201490390A1 (ru) | 2014-05-30 |
JP2014521681A (ja) | 2014-08-28 |
WO2013017689A1 (de) | 2013-02-07 |
EP2739273A1 (de) | 2014-06-11 |
DE102011080390B3 (de) | 2012-07-12 |
KR20140054167A (ko) | 2014-05-08 |
US20140155845A1 (en) | 2014-06-05 |
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