JP5711276B2 - 粒子分析器におけるパルスパラメータの生成 - Google Patents

粒子分析器におけるパルスパラメータの生成 Download PDF

Info

Publication number
JP5711276B2
JP5711276B2 JP2012557209A JP2012557209A JP5711276B2 JP 5711276 B2 JP5711276 B2 JP 5711276B2 JP 2012557209 A JP2012557209 A JP 2012557209A JP 2012557209 A JP2012557209 A JP 2012557209A JP 5711276 B2 JP5711276 B2 JP 5711276B2
Authority
JP
Japan
Prior art keywords
pulse
detection window
particle
pulse detection
primary
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
JP2012557209A
Other languages
English (en)
Japanese (ja)
Other versions
JP2013522601A (ja
JP2013522601A5 (enExample
Inventor
クリストファー ディー． ロフストローム，
クリストファー ディー． ロフストローム，
ダニエル エヌ． フォックス，
ダニエル エヌ． フォックス，
トーマス エル． スラシャー，
トーマス エル． スラシャー，
デイビッド シー． ネッケルズ，
デイビッド シー． ネッケルズ，
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Beckman Coulter Inc
Original Assignee
Beckman Coulter Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Beckman Coulter Inc filed Critical Beckman Coulter Inc
Publication of JP2013522601A publication Critical patent/JP2013522601A/ja
Publication of JP2013522601A5 publication Critical patent/JP2013522601A5/ja
Application granted granted Critical
Publication of JP5711276B2 publication Critical patent/JP5711276B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Images

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N15/1429—Signal processing
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N15/1425—Optical investigation techniques, e.g. flow cytometry using an analyser being characterised by its control arrangement
    • G01N15/1427—Optical investigation techniques, e.g. flow cytometry using an analyser being characterised by its control arrangement with the synchronisation of components, a time gate for operation of components, or suppression of particle coincidences
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N15/1456—Optical investigation techniques, e.g. flow cytometry without spatial resolution of the texture or inner structure of the particle, e.g. processing of pulse signals
    • G01N15/1459—Optical investigation techniques, e.g. flow cytometry without spatial resolution of the texture or inner structure of the particle, e.g. processing of pulse signals the analysis being performed on a sample stream
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N15/1434—Optical arrangements
    • G01N2015/1438—Using two lasers in succession

Landscapes

  • Chemical & Material Sciences (AREA)
  • Biochemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Dispersion Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Engineering & Computer Science (AREA)
  • Signal Processing (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
JP2012557209A 2010-03-10 2011-03-09 粒子分析器におけるパルスパラメータの生成 Active JP5711276B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US31261610P 2010-03-10 2010-03-10
US61/312,616 2010-03-10
PCT/US2011/027716 WO2011112697A1 (en) 2010-03-10 2011-03-09 Generating pulse parameters in a particle analyzer

Publications (3)

Publication Number Publication Date
JP2013522601A JP2013522601A (ja) 2013-06-13
JP2013522601A5 JP2013522601A5 (enExample) 2014-04-10
JP5711276B2 true JP5711276B2 (ja) 2015-04-30

Family

ID=44123329

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2012557209A Active JP5711276B2 (ja) 2010-03-10 2011-03-09 粒子分析器におけるパルスパラメータの生成

Country Status (9)

Country Link
US (1) US8754390B2 (enExample)
EP (1) EP2545357B1 (enExample)
JP (1) JP5711276B2 (enExample)
KR (1) KR101805941B1 (enExample)
CN (1) CN102792147B (enExample)
AU (1) AU2011224429B2 (enExample)
BR (1) BR112012022653B1 (enExample)
SG (1) SG183932A1 (enExample)
WO (1) WO2011112697A1 (enExample)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2011224429B2 (en) * 2010-03-10 2014-09-04 Beckman Coulter, Inc. Generating pulse parameters in a particle analyzer
US9897530B2 (en) 2011-08-25 2018-02-20 Sony Corporation Compensation of motion-related error in a stream of moving micro-entities
US9677990B2 (en) * 2014-04-30 2017-06-13 Particles Plus, Inc. Particle counter with advanced features
US11579072B2 (en) 2013-03-15 2023-02-14 Particles Plus, Inc. Personal air quality monitoring system
US10352844B2 (en) 2013-03-15 2019-07-16 Particles Plus, Inc. Multiple particle sensors in a particle counter
US10983040B2 (en) 2013-03-15 2021-04-20 Particles Plus, Inc. Particle counter with integrated bootloader
US12044611B2 (en) 2013-03-15 2024-07-23 Particles Plus, Inc. Particle counter with integrated bootloader
WO2015122920A1 (en) * 2014-02-14 2015-08-20 Perkinelmer Health Sciences, Inc. Systems and methods for automated analysis of output in single particle inductively coupled plasma mass spectrometry and similar data sets
JP2017511884A (ja) * 2014-03-06 2017-04-27 ライフ テクノロジーズ コーポレーション 流体装置システムを診断するため及びフローサイトメータ用のデータ処理設定を決定するためのシステム及び方法
CN104977238B (zh) * 2014-04-10 2018-02-16 深圳迈瑞生物医疗电子股份有限公司 脉冲延迟自适应校准装置、方法和细胞分析仪
CN107636472B (zh) 2014-11-06 2020-09-15 基纽拜奥股份有限公司 微滴速度检测
JP6596987B2 (ja) * 2015-07-02 2019-10-30 富士電機株式会社 粒子計測装置
US9863864B2 (en) 2015-09-15 2018-01-09 Bio-Rad Technologies, Inc. Threshold selector for flow cytometer
DE102020200193A1 (de) * 2020-01-09 2021-07-15 Albert-Ludwigs-Universität Freiburg Anordnung zur optischen Vorkonditionierung einer optisch aktivierbaren biologischen Probe
US11988591B2 (en) 2020-07-01 2024-05-21 Particles Plus, Inc. Modular optical particle counter sensor and apparatus
CN114062230B (zh) * 2020-07-30 2025-04-04 深圳迈瑞生物医疗电子股份有限公司 血细胞脉冲信号识别方法、流式细胞仪及可读存储介质
CN112903569A (zh) * 2021-01-20 2021-06-04 贝克曼库尔特生物科技（苏州）有限公司 用于计算液滴延迟时间的系统和方法以及分选装置
KR102325241B1 (ko) * 2021-09-08 2021-11-11 대한민국 저출력 레이저 미세먼지 감지 시스템 및 방법
CN114327267B (zh) * 2021-12-24 2023-08-22 深圳大普微电子科技有限公司 一种闪存控制器、延迟调整方法及存储设备
US20250180461A1 (en) * 2022-01-31 2025-06-05 Sony Group Corporation Biological sample analysis system, method for setting light data acquisition section in biological sample analysis system, and information processing device

Family Cites Families (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3936741A (en) * 1973-10-17 1976-02-03 Coulter Electronics, Inc. Method and apparatus for providing primary coincidence correction during particle analysis utilizing time generation techniques
US4325483A (en) * 1979-08-20 1982-04-20 Ortho Diagnostics, Inc. Method for detecting and controlling flow rates of the droplet forming stream of an electrostatic particle sorting apparatus
US5056918A (en) * 1989-03-03 1991-10-15 Coulter Electronics Of New England, Inc. Method and apparatus for particle size analysis
US4953978A (en) * 1989-03-03 1990-09-04 Coulter Electronics Of New England, Inc. Particle size analysis utilizing polarization intensity differential scattering
US5104221A (en) * 1989-03-03 1992-04-14 Coulter Electronics Of New England, Inc. Particle size analysis utilizing polarization intensity differential scattering
JP3102935B2 (ja) * 1991-11-20 2000-10-23 シスメックス株式会社 イメージングフローサイトメータ
JPH0792077A (ja) * 1993-09-24 1995-04-07 Canon Inc 粒子解析装置
US7219016B2 (en) * 2001-04-20 2007-05-15 Yale University Systems and methods for automated analysis of cells and tissues
AU2003279801A1 (en) * 2002-10-02 2004-04-23 Airadvice, Inc. Method and apparatus for particle sizing
WO2005091893A2 (en) * 2004-03-03 2005-10-06 Dakocytomation Denmark A/S System for high dynamic range analysis in flow cytometry
US20060078998A1 (en) * 2004-09-28 2006-04-13 Singulex, Inc. System and methods for sample analysis
US20070269348A1 (en) * 2006-05-19 2007-11-22 Cytopeia Incorporated Enhanced droplet flow cytometer system and method
EP2062056B1 (en) * 2006-09-29 2019-04-10 Luminex Corporation Differentiation of flow cytometry pulses and applications
US7945428B2 (en) * 2007-03-23 2011-05-17 Beckman Coulter, Inc. Multi-gain adaptive linear processing and gated digital system for use in flow cytometry
WO2009028063A1 (ja) * 2007-08-30 2009-03-05 Mitsui Engineering & Shipbuilding Co., Ltd. Ｆｒｅｔ検出方法及び装置
WO2009149733A1 (en) * 2008-06-13 2009-12-17 Embl Heidelberg Next generation flow cytometer sorter
EP2353042A4 (en) * 2008-10-14 2013-06-26 Sanford Burnham Med Res Inst AUTOMATED SCANNING CYTOMETRY WITH CHROMATIC ABERRATION FOR MULTIPLANAR IMAGE RECORDING
US8557587B2 (en) * 2009-01-07 2013-10-15 Xy, Llc Self-tuning, biologically modeled sorter
JP4620786B2 (ja) * 2009-02-17 2011-01-26 三井造船株式会社 蛍光検出方法、蛍光検出装置及びプログラム
EP2411133B1 (en) * 2009-03-25 2013-12-18 Eastman Kodak Company Droplet generator
US20100256943A1 (en) * 2009-04-06 2010-10-07 University Of Pittsburgh - Of The Commonwealth System Of Higher Education Configuration of initial control parameters in photodetectors for multi-color flow cytometry
US8004674B2 (en) * 2009-06-02 2011-08-23 Accuri Cytometers, Inc. Data collection system and method for a flow cytometer
US9364831B2 (en) * 2009-08-08 2016-06-14 The Regents Of The University Of California Pulsed laser triggered high speed microfluidic switch and applications in fluorescent activated cell sorting
US8922646B2 (en) * 2010-03-09 2014-12-30 Beckman Coulter, Inc. Calculate drop delay for flow cytometry systems and methods
AU2011224429B2 (en) * 2010-03-10 2014-09-04 Beckman Coulter, Inc. Generating pulse parameters in a particle analyzer
US8528427B2 (en) * 2010-10-29 2013-09-10 Becton, Dickinson And Company Dual feedback vacuum fluidics for a flow-type particle analyzer
EP2769203B1 (en) * 2011-10-21 2019-01-16 Acea Biosciences, Inc. System and method for detecting multiple-excitation-induced light in a flow channel

Also Published As

Publication number Publication date
US8754390B2 (en) 2014-06-17
SG183932A1 (en) 2012-10-30
AU2011224429A1 (en) 2012-09-27
WO2011112697A1 (en) 2011-09-15
EP2545357A1 (en) 2013-01-16
CN102792147B (zh) 2015-05-13
BR112012022653A2 (pt) 2016-11-01
AU2011224429B2 (en) 2014-09-04
KR20130027463A (ko) 2013-03-15
EP2545357B1 (en) 2021-06-02
BR112012022653B1 (pt) 2020-03-10
CN102792147A (zh) 2012-11-21
JP2013522601A (ja) 2013-06-13
US20110303859A1 (en) 2011-12-15
KR101805941B1 (ko) 2017-12-06

Similar Documents

Publication Publication Date Title
JP5711276B2 (ja) 粒子分析器におけるパルスパラメータの生成
EP2732395B1 (en) Compensation of motion-related error in a stream of moving mirco-entities
JP5139885B2 (ja) 蛍光解析装置及び解析方法
CN101965508B (zh) 识别流中的微粒的系统和方法
JP5323829B2 (ja) 細胞の識別およびソーティング方法およびその装置
CA2664456C (en) Differentiation of flow cytometry pulses and applications
JP4965561B2 (ja) サイトメータ細胞計数及びサイズ測定システム
US7130046B2 (en) Data frame selection for cytometer analysis
EP2908117A2 (en) Spatial modulation of light to determine object length
WO2014186461A1 (en) Scanning image flow cytometer
JP2013522601A5 (enExample)
CN102749273B (zh) 一种气溶胶颗粒粒径分类检测系统
EP3521807B1 (en) Microparticle measurement device and microparticle measurement method
EP3511691B1 (en) Microparticle measurement device and microparticle measurement method
CN105021572A (zh) 尿样本分析方法及尿样本分析装置
EP4528250A1 (en) Biological sample analysis system, information processing device, information processing method, and biological sample analysis method
WO2025085298A1 (en) Flow cytometer bead detection and spillover matrix
US20150044763A1 (en) Fret measurement device and fret measurement method

Legal Events

Date Code Title Description
A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20140220

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20140220

A977 Report on retrieval

Free format text: JAPANESE INTERMEDIATE CODE: A971007

Effective date: 20140919

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20141008

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20141110

TRDD Decision of grant or rejection written
A01 Written decision to grant a patent or to grant a registration (utility model)

Free format text: JAPANESE INTERMEDIATE CODE: A01

Effective date: 20150206

A61 First payment of annual fees (during grant procedure)

Free format text: JAPANESE INTERMEDIATE CODE: A61

Effective date: 20150305

R150 Certificate of patent or registration of utility model

Ref document number: 5711276

Country of ref document: JP

Free format text: JAPANESE INTERMEDIATE CODE: R150

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250