JP5701212B2 - 肺癌バイオマーカーとその使用 - Google Patents

肺癌バイオマーカーとその使用 Download PDF

Info

Publication number
JP5701212B2
JP5701212B2 JP2011526308A JP2011526308A JP5701212B2 JP 5701212 B2 JP5701212 B2 JP 5701212B2 JP 2011526308 A JP2011526308 A JP 2011526308A JP 2011526308 A JP2011526308 A JP 2011526308A JP 5701212 B2 JP5701212 B2 JP 5701212B2
Authority
JP
Japan
Prior art keywords
biomarker
biomarkers
individual
lung cancer
sample
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
JP2011526308A
Other languages
English (en)
Japanese (ja)
Other versions
JP2012502281A (ja
JP2012502281A5 (https=
Inventor
ゴールド,ラリー
スタントン,マーティ
ブロディ,エドワード・エヌ
オストロフ,レイチェル・エム
ジチ,ドミニク
スチュアート,アレックス・エイ・イー
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Somalogic Inc
Original Assignee
Somalogic Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Somalogic Inc filed Critical Somalogic Inc
Publication of JP2012502281A publication Critical patent/JP2012502281A/ja
Publication of JP2012502281A5 publication Critical patent/JP2012502281A5/ja
Application granted granted Critical
Publication of JP5701212B2 publication Critical patent/JP5701212B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/575Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/5752Immunoassay; Biospecific binding assay; Materials therefor for cancer of the lungs
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • GPHYSICS
    • G06COMPUTING OR CALCULATING; COUNTING
    • G06FELECTRIC DIGITAL DATA PROCESSING
    • G06F17/00Digital computing or data processing equipment or methods, specially adapted for specific functions
    • G06F17/10Complex mathematical operations
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/12Pulmonary diseases
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A90/00Technologies having an indirect contribution to adaptation to climate change
    • Y02A90/10Information and communication technologies [ICT] supporting adaptation to climate change, e.g. for weather forecasting or climate simulation

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Pathology (AREA)
  • Genetics & Genomics (AREA)
  • General Engineering & Computer Science (AREA)
  • Data Mining & Analysis (AREA)
  • Theoretical Computer Science (AREA)
  • Mathematical Physics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Databases & Information Systems (AREA)
  • Algebra (AREA)
  • Mathematical Analysis (AREA)
  • Mathematical Optimization (AREA)
  • Plant Pathology (AREA)
  • Pure & Applied Mathematics (AREA)
  • Computational Mathematics (AREA)
  • Software Systems (AREA)
  • Biophysics (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
JP2011526308A 2008-09-09 2009-09-09 肺癌バイオマーカーとその使用 Active JP5701212B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US9559308P 2008-09-09 2008-09-09
US61/095,593 2008-09-09
US15283709P 2009-02-16 2009-02-16
US61/152,837 2009-02-16
PCT/US2009/056399 WO2010030697A1 (en) 2008-09-09 2009-09-09 Lung cancer biomarkers and uses thereof

Publications (3)

Publication Number Publication Date
JP2012502281A JP2012502281A (ja) 2012-01-26
JP2012502281A5 JP2012502281A5 (https=) 2012-09-13
JP5701212B2 true JP5701212B2 (ja) 2015-04-15

Family

ID=42005456

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2011526308A Active JP5701212B2 (ja) 2008-09-09 2009-09-09 肺癌バイオマーカーとその使用

Country Status (14)

Country Link
EP (1) EP2340506B1 (https=)
JP (1) JP5701212B2 (https=)
KR (1) KR101658347B1 (https=)
CN (2) CN102209968B (https=)
AU (2) AU2009291811B2 (https=)
CA (3) CA3152591C (https=)
DK (1) DK2340506T3 (https=)
ES (1) ES2559758T3 (https=)
GB (1) GB2478441B (https=)
HK (1) HK1204062A1 (https=)
HR (1) HRP20160127T1 (https=)
MX (1) MX2011002322A (https=)
SI (1) SI2340506T1 (https=)
WO (1) WO2010030697A1 (https=)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10359425B2 (en) 2008-09-09 2019-07-23 Somalogic, Inc. Lung cancer biomarkers and uses thereof
WO2012006632A2 (en) * 2010-07-09 2012-01-12 Somalogic, Inc. Lung cancer biomarkers and uses thereof
KR101900016B1 (ko) 2009-03-12 2018-09-20 캔서 프리벤션 앤 큐어, 리미티드 폐 질환의 동정, 평가, 예방 및 치료 방법과, 성별에 기초하는 질환의 동정, 평가, 예방 및 치료를 포함하는 상기 방법의 키트
SG187045A1 (en) 2010-08-13 2013-02-28 Somalogic Inc Pancreatic cancer biomarkers and uses thereof
CA2832480C (en) * 2011-04-07 2022-05-31 The Scripps Research Institute High-throughput screening for compounds modulating expression of cellular macromolecules
EP3825693A1 (en) * 2011-04-29 2021-05-26 Cancer Prevention And Cure, Ltd. Methods of identification and diagnosis of lung diseases using classification systems and kits thereof
CA3064363C (en) * 2011-10-24 2022-05-17 Somalogic, Inc. Non-small cell lung cancer biomarkers and uses thereof
US11913957B2 (en) 2011-12-21 2024-02-27 Biodesix, Inc. Compositions, methods and kits for diagnosis of lung cancer
US9201044B2 (en) 2011-12-21 2015-12-01 Integrated Diagnostics, Inc. Compositions, methods and kits for diagnosis of lung cancer
US9304137B2 (en) 2011-12-21 2016-04-05 Integrated Diagnostics, Inc. Compositions, methods and kits for diagnosis of lung cancer
WO2013121374A2 (en) * 2012-02-17 2013-08-22 Koninklijke Philips N.V. Acute lung injury (ali)/acute respiratory distress syndrome (ards) assessment and monitoring
WO2014074682A1 (en) 2012-11-07 2014-05-15 Somalogic, Inc. Chronic obstructive pulmonary disease (copd) biomarkers and uses thereof
BR112016010322A2 (pt) * 2013-11-07 2017-08-08 Medial Res Ltd Método computadorizado de avaliação de risco de câncer de pulmão, meio legível por computador, sistema de avaliação de câncer de pulmão, e método de geração de um classificador para avaliação de risco de câncer de pulmão
JP6857185B2 (ja) * 2015-09-11 2021-04-14 アプタマー サイエンス インコーポレイテッドAptamer Sciences Inc. 非小細胞肺癌診断用タンパク質バイオマーカーパネル及びこれを用いた非小細胞肺癌診断方法
FR3050269B1 (fr) * 2016-04-15 2018-05-11 Ecole Superieure De Physique Et De Chimie Industrielles De La Ville De Paris (Espci) Procede de selection et de recuperation de produits et systeme associe
CN105823665A (zh) * 2016-05-13 2016-08-03 北京九州柏林生物科技有限公司 生物组织样本制备套液
AU2017281099A1 (en) 2016-06-21 2019-01-03 The Wistar Institute Of Anatomy And Biology Compositions and methods for diagnosing lung cancers using gene expression profiles
JP6280997B1 (ja) * 2016-10-31 2018-02-14 株式会社Preferred Networks 疾患の罹患判定装置、疾患の罹患判定方法、疾患の特徴抽出装置及び疾患の特徴抽出方法
CN110709936A (zh) 2017-04-04 2020-01-17 肺癌蛋白质组学有限责任公司 用于早期肺癌预后的基于血浆的蛋白质概况分析
KR102633621B1 (ko) 2017-09-01 2024-02-05 벤 바이오사이언시스 코포레이션 진단 및 치료 모니터링용 바이오마커로서의 당펩티드의 식별 및 용도
CA3083097A1 (en) 2017-11-22 2019-05-31 Gritstone Oncology, Inc. Reducing junction epitope presentation for neoantigens
US12227808B2 (en) 2017-12-19 2025-02-18 The Wistar Institute Of Anatomy And Biology Compostions and methods for diagnosing lung cancers using gene expression profiles
EP3810563A4 (en) * 2018-06-22 2022-03-23 Somalogic, Inc. IMPROVED PROTEOMIC MULTIPLEX TESTS
JP7691373B2 (ja) * 2019-06-21 2025-06-11 ナショナル ユニヴァーシティー オブ シンガポール 肺癌の可能性を判定するための方法
CN110579611B (zh) * 2019-09-18 2023-01-31 郑州大学 一种用于肺癌早期筛查和诊断的联合检测血清标志物、试剂盒及检测方法
CN111047609B (zh) * 2020-03-13 2020-07-24 北京深睿博联科技有限责任公司 肺炎病灶分割方法和装置
WO2022073502A1 (zh) * 2020-10-10 2022-04-14 中山大学肿瘤防治中心(中山大学附属肿瘤医院、中山大学肿瘤研究所) 生物标志物在制备肺癌检测试剂中的用途和方法
CN112557514B (zh) * 2020-12-22 2021-09-21 中国海洋大学 手持式海底沉积物样品剖面声学全自动测量装置
WO2025137139A1 (en) * 2023-12-18 2025-06-26 Caris Mpi, Inc. Dynamic tissue typing

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6596503B1 (en) * 2000-08-18 2003-07-22 East Carolina University Monoclonal antibody DS6, tumor-associated antigen CA6, and methods of use thereof
NZ528205A (en) * 2001-03-12 2006-09-29 Monogen Inc Cell-based detection and differentiation of disease status in a cytological sample using a panel comprising a plurality of probes
US20030190602A1 (en) * 2001-03-12 2003-10-09 Monogen, Inc. Cell-based detection and differentiation of disease states
CA2444691A1 (en) * 2001-04-18 2002-10-31 Protein Design Labs, Inc. Methods of diagnosis of lung cancer, compositions and methods of screening for modulators of lung cancer
US8014952B2 (en) * 2002-12-18 2011-09-06 Queen Elizabeth Hospital Serum biomarkers in lung cancer
CN1225477C (zh) * 2003-03-28 2005-11-02 上海市疾病预防控制中心 肺癌早期血清特异蛋白及其应用
CN1455257A (zh) * 2003-05-23 2003-11-12 北京师范大学 一种利用表面修饰蛋白芯片进行肺癌诊断方法
ATE496142T1 (de) * 2004-03-23 2011-02-15 Oncotherapy Science Inc Verfahren zur diagnose von nicht-kleinzelligem lungenkrebs
JP2005304497A (ja) * 2004-03-25 2005-11-04 Joji Inasawa 特定の癌関連遺伝子を用いる癌の検出方法及び癌の抑制方法
CA2578680C (en) * 2004-04-15 2011-06-14 University Of Florida Research Foundation, Inc. Proteolytic markers as diagnostic biomarkers for cancer, organ injury and muscle rehabilitation/exercise overtraining
AU2005236075A1 (en) * 2004-04-26 2005-11-03 Children's Medical Center Corporation Platelet biomarkers for the detection of disease
MX2007001357A (es) * 2004-08-02 2009-08-07 Childrens Medical Center Biomarcadores de plaquetas para cancer.
CN1873417A (zh) * 2005-06-02 2006-12-06 中国医学科学院肿瘤医院肿瘤研究所 一种用于诊断肺癌的蛋白质芯片
EP1969363B1 (en) * 2005-12-22 2016-11-30 Abbott Molecular Inc. Methods and marker combinations for screening for predisposition to lung cancer
US7908091B2 (en) * 2006-03-17 2011-03-15 Prometheus Laboratories Inc. Methods of predicting and monitoring tyrosine kinase inhibitor therapy
CA2666584A1 (en) * 2006-10-17 2008-04-24 Synergenz Bioscience Limited Methods and compositions for assessment of pulmonary function and disorders
US20110119776A1 (en) * 2007-02-05 2011-05-19 Wong Kwok-Kin Methods of diagnosing and prognosing lung cancer
KR100846354B1 (ko) * 2007-03-21 2008-07-15 (주) 프로탄바이오 혈청 당단백질부터 분리한 폐암 진단용 마커
US20100184773A1 (en) * 2007-05-18 2010-07-22 Heinz-Josef Lenz Germline Polymorphisms in the Angiogenic Pathway Predict Tumor Recurrence in Cancer Therapy
US7888051B2 (en) * 2007-09-11 2011-02-15 Cancer Prevention And Cure, Ltd. Method of identifying biomarkers in human serum indicative of pathologies of human lung tissues
WO2010003772A1 (en) * 2008-06-16 2010-01-14 Siemens Medical Solutions Diagnostics Gmbh Method for predicting adverse response to erythropoietin in breast cancer treatment
US10359425B2 (en) * 2008-09-09 2019-07-23 Somalogic, Inc. Lung cancer biomarkers and uses thereof
CA2789494C (en) * 2010-02-10 2021-08-17 The Regents Of The University Of California Salivary biomarkers for lung cancer detection

Also Published As

Publication number Publication date
CA3152591C (en) 2023-08-29
GB2478441A (en) 2011-09-07
HK1204062A1 (en) 2015-11-06
KR101658347B1 (ko) 2016-09-21
EP2340506A1 (en) 2011-07-06
EP2340506B1 (en) 2015-11-11
CA2734535A1 (en) 2010-03-18
AU2015249113B2 (en) 2017-09-07
CA3011730C (en) 2022-05-17
AU2009291811B2 (en) 2015-10-29
GB2478441B (en) 2013-03-27
ES2559758T3 (es) 2016-02-15
JP2012502281A (ja) 2012-01-26
AU2015249113A1 (en) 2015-11-12
CN102209968B (zh) 2016-05-04
CA3152591A1 (en) 2010-03-18
EP2340506A4 (en) 2012-02-15
HK1153834A1 (en) 2012-04-05
WO2010030697A1 (en) 2010-03-18
CN104198709A (zh) 2014-12-10
AU2009291811A1 (en) 2010-03-18
KR20110063753A (ko) 2011-06-14
CN102209968A (zh) 2011-10-05
MX2011002322A (es) 2011-05-10
GB201106053D0 (en) 2011-05-25
SI2340506T1 (sl) 2016-02-29
DK2340506T3 (en) 2016-02-08
CA2734535C (en) 2018-08-28
HRP20160127T1 (hr) 2016-03-11
CA3011730A1 (en) 2010-03-18

Similar Documents

Publication Publication Date Title
JP5701212B2 (ja) 肺癌バイオマーカーとその使用
JP5905003B2 (ja) 肺癌バイオマーカーとその使用
JP5986638B2 (ja) 肺癌バイオマーカーおよびその使用
CN103415624B (zh) 胰腺癌生物标记及其用途
US20120143805A1 (en) Cancer Biomarkers and Uses Thereof
WO2011031344A1 (en) Cancer biomarkers and uses thereof
CN103429753A (zh) 间皮瘤生物标记及其用途
US20220065872A1 (en) Lung Cancer Biomarkers and Uses Thereof
HK1229002A1 (en) Lung cancer biomarkers and uses thereof
HK1229002A (en) Lung cancer biomarkers and uses thereof
HK1229002B (en) Lung cancer biomarkers and uses thereof
HK1229003A1 (en) Pancreatic cancer biomarkers and uses thereof

Legal Events

Date Code Title Description
A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20120725

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20120725

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20120725

A977 Report on retrieval

Free format text: JAPANESE INTERMEDIATE CODE: A971007

Effective date: 20130213

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20131209

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20140307

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20140731

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20140815

TRDD Decision of grant or rejection written
A01 Written decision to grant a patent or to grant a registration (utility model)

Free format text: JAPANESE INTERMEDIATE CODE: A01

Effective date: 20150119

A61 First payment of annual fees (during grant procedure)

Free format text: JAPANESE INTERMEDIATE CODE: A61

Effective date: 20150217

R150 Certificate of patent or registration of utility model

Ref document number: 5701212

Country of ref document: JP

Free format text: JAPANESE INTERMEDIATE CODE: R150

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

S533 Written request for registration of change of name

Free format text: JAPANESE INTERMEDIATE CODE: R313533

R350 Written notification of registration of transfer

Free format text: JAPANESE INTERMEDIATE CODE: R350

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250