JP5691171B2 - 免疫誘導剤 - Google Patents

免疫誘導剤 Download PDF

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Publication number
JP5691171B2
JP5691171B2 JP2009546597A JP2009546597A JP5691171B2 JP 5691171 B2 JP5691171 B2 JP 5691171B2 JP 2009546597 A JP2009546597 A JP 2009546597A JP 2009546597 A JP2009546597 A JP 2009546597A JP 5691171 B2 JP5691171 B2 JP 5691171B2
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Prior art keywords
polypeptide
cells
immunity
seq
cancer
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Japanese (ja)
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JPWO2010016525A1 (ja
Inventor
文義 岡野
文義 岡野
まさき 清水
まさき 清水
孝則 齋藤
孝則 齋藤
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Toray Industries Inc
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Toray Industries Inc
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Publication of JPWO2010016525A1 publication Critical patent/JPWO2010016525A1/ja
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08—Peptides having 5 to 11 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/10—Peptides having 12 to 20 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/0005—Vertebrate antigens
    • A61K39/0011—Cancer antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00—Cellular immunotherapy
    • A61K40/30—Cellular immunotherapy characterised by the recombinant expression of specific molecules in the cells of the immune system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4748—Tumour specific antigens; Tumour rejection antigen precursors [TRAP], e.g. MAGE
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0634—Cells from the blood or the immune system
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0634—Cells from the blood or the immune system
    • C12N5/0636—T lymphocytes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/53—DNA (RNA) vaccination
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2121/00—Preparations for use in therapy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Genetics & Genomics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biotechnology (AREA)
  • Wood Science & Technology (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Microbiology (AREA)
  • Hematology (AREA)
  • General Engineering & Computer Science (AREA)
  • Cell Biology (AREA)
  • Molecular Biology (AREA)
  • Toxicology (AREA)
  • Biophysics (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Mycology (AREA)
  • Marine Sciences & Fisheries (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
JP2009546597A 2008-08-05 2009-08-05 免疫誘導剤 Active JP5691171B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2009546597A JP5691171B2 (ja) 2008-08-05 2009-08-05 免疫誘導剤

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP2008202065 2008-08-05
JP2008202065 2008-08-05
PCT/JP2009/063881 WO2010016525A1 (ja) 2008-08-05 2009-08-05 免疫誘導剤
JP2009546597A JP5691171B2 (ja) 2008-08-05 2009-08-05 免疫誘導剤

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2014225626A Division JP5962739B2 (ja) 2008-08-05 2014-11-05 免疫誘導剤

Publications (2)

Publication Number Publication Date
JPWO2010016525A1 JPWO2010016525A1 (ja) 2012-01-26
JP5691171B2 true JP5691171B2 (ja) 2015-04-01

Family

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JP2009546597A Active JP5691171B2 (ja) 2008-08-05 2009-08-05 免疫誘導剤
JP2014225626A Active JP5962739B2 (ja) 2008-08-05 2014-11-05 免疫誘導剤

Family Applications After (1)

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JP2014225626A Active JP5962739B2 (ja) 2008-08-05 2014-11-05 免疫誘導剤

Country Status (16)

Country Link
US (2) US8454968B2 (enExample)
EP (2) EP2324842B1 (enExample)
JP (2) JP5691171B2 (enExample)
KR (3) KR101669827B1 (enExample)
CN (2) CN102112146B (enExample)
AU (2) AU2009278385B2 (enExample)
BR (2) BR122020027042B1 (enExample)
CA (1) CA2732283C (enExample)
DK (2) DK2324842T3 (enExample)
ES (2) ES2619322T3 (enExample)
HU (1) HUE031343T2 (enExample)
MX (2) MX339277B (enExample)
PL (2) PL2324842T3 (enExample)
PT (2) PT2837383T (enExample)
RU (2) RU2511039C2 (enExample)
WO (1) WO2010016525A1 (enExample)

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DK2322221T3 (da) 2008-08-05 2014-09-01 Toray Industries Farmaceutisk sammensætning til behandling og forebyggelse af cancer
MX337991B (es) 2008-08-05 2016-03-30 Toray Industries Metodo para detectar cancer.
AU2011211699B2 (en) 2010-02-04 2015-01-22 Toray Industries, Inc. Pharmaceutical composition for treating and/or preventing cancer
JP5845899B2 (ja) 2010-02-04 2016-01-20 東レ株式会社 癌の治療及び/又は予防用医薬組成物
HUE040012T2 (hu) * 2010-02-04 2019-02-28 Toray Industries Gyógyászati ágens rák kezelésére és/vagy megelõzésére
BR112012018951C8 (pt) 2010-02-04 2020-06-23 Toray Industries anticorpo monoclonal, composição farmacêutica, combinação farmacêutica, uso de um anticorpo, uso de uma composição farmacêutica e uso de uma combinação farmacêutica
KR101842893B1 (ko) * 2010-02-04 2018-03-28 도레이 카부시키가이샤 암의 치료 및/또는 예방용 의약 조성물
KR101871704B1 (ko) * 2010-02-04 2018-06-27 도레이 카부시키가이샤 암의 치료 및/또는 예방용 의약 조성물
CA2836568C (en) * 2011-05-19 2020-07-21 Toray Industries, Inc. Immunity induction agent
PT2740796T (pt) * 2011-08-04 2017-07-26 Toray Industries Composição farmacêutica para o tratamento e/ou profilaxia de cancro
CN103764825B (zh) * 2011-08-04 2015-09-02 东丽株式会社 癌的治疗和/或预防用药物组合物
ES2672695T3 (es) * 2011-08-04 2018-06-15 Toray Industries, Inc. Composición farmacéutica para el tratamiento y/o la profilaxis del cáncer
MX348579B (es) 2011-08-04 2017-06-20 Toray Industries Composicion farmaceutica para el tratamiento y/o prevencion del cancer.
KR101968499B1 (ko) * 2011-08-04 2019-04-12 도레이 카부시키가이샤 암의 치료 및/또는 예방용 의약 조성물
BR112014002619A2 (pt) 2011-08-04 2018-10-09 Toray Industries, Inc composição farmacêutica e método de tratamento e/ou prevenção de câncer pancreático e combinação farmacêutica
ES2629061T3 (es) 2011-08-04 2017-08-07 Toray Industries, Inc. Método para la detección de cáncer pancreático
ES2739380T3 (es) 2012-02-21 2020-01-30 Toray Industries Composición farmacéutica para el tratamiento del cáncer
AU2013223143B2 (en) 2012-02-21 2017-12-21 Toray Industries, Inc. Pharmaceutical composition for treatment and/or prevention of cancer
MX357505B (es) 2012-02-21 2018-07-12 Toray Industries Composicion farmaceutica para el tratamiento y/o prevencion del cancer.
IN2014KN01714A (enExample) 2012-02-21 2015-10-23 Toray Industries
US9428581B2 (en) 2012-03-30 2016-08-30 Toray Industries, Inc. Pharmaceutical composition for treatment and/or prevention of gallbladder cancer
PT2832365T (pt) 2012-03-30 2018-01-24 Toray Industries Composição farmacêutica para o tratamento e/ou prevenção do cancro hepático
CA2879185C (en) 2012-07-19 2021-08-24 Toray Industries, Inc. Method for detecting cancer
WO2014014082A1 (ja) 2012-07-19 2014-01-23 東レ株式会社 癌の検出方法
CA2918989C (en) 2013-08-09 2021-11-02 Toray Industries, Inc. Pharmaceutical composition for treatment and/or prevention of cancer
MX390696B (es) * 2015-04-30 2025-03-21 Toray Industries Agente inductor de inmunidad.
WO2018079740A1 (ja) * 2016-10-28 2018-05-03 東レ株式会社 癌の治療及び/又は予防用医薬組成物
WO2019189780A1 (ja) * 2018-03-30 2019-10-03 東レ株式会社 癌の治療及び/又は予防用医薬組成物
CN109206502B (zh) * 2018-09-26 2022-03-04 东北农业大学 一种猫干扰素ω及其制备方法和在抗病毒中的应用
CN109206501B (zh) * 2018-09-26 2022-03-04 东北农业大学 猫干扰素ω、其编码基因及其在抗病毒方面的应用
CA3175127A1 (en) 2020-03-12 2021-09-16 Toray Industries, Inc. Medicament for treatment and/or prevention of cancer
JP7852926B2 (ja) * 2020-06-26 2026-04-28 ファイム ファーマ リミテッド 乾癬及び他の自己免疫疾患抗原免疫モジュレータ(aim)治療プラットフォーム

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WO2002083070A2 (en) * 2001-04-10 2002-10-24 Corixa Corporation Compounds for immunotherapy and diagnosis of colon cancer and methods for their use
US20030190640A1 (en) * 2001-05-31 2003-10-09 Mary Faris Genes expressed in prostate cancer
JP2008500033A (ja) * 2004-05-25 2008-01-10 イマティクス バイオテクノロジーズ ゲーエムベーハー Mhc分子を結合する腫瘍関連ペプチド
WO2008088583A2 (en) * 2006-08-30 2008-07-24 Immunotope, Inc Cytotoxic t-lymphocyte-inducing immunogens for prevention, treatment, and diagnosis of cancer

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WO2002083070A2 (en) * 2001-04-10 2002-10-24 Corixa Corporation Compounds for immunotherapy and diagnosis of colon cancer and methods for their use
US20030190640A1 (en) * 2001-05-31 2003-10-09 Mary Faris Genes expressed in prostate cancer
JP2008500033A (ja) * 2004-05-25 2008-01-10 イマティクス バイオテクノロジーズ ゲーエムベーハー Mhc分子を結合する腫瘍関連ペプチド
WO2008088583A2 (en) * 2006-08-30 2008-07-24 Immunotope, Inc Cytotoxic t-lymphocyte-inducing immunogens for prevention, treatment, and diagnosis of cancer

Also Published As

Publication number Publication date
RU2639518C2 (ru) 2017-12-21
BRPI0912462A2 (enExample) 2016-02-02
MX348464B (es) 2017-06-14
KR101669827B1 (ko) 2016-10-27
KR20170128637A (ko) 2017-11-22
JP2015061847A (ja) 2015-04-02
DK2837383T3 (en) 2017-03-20
US9592281B2 (en) 2017-03-14
CA2732283C (en) 2017-12-05
US20130230488A1 (en) 2013-09-05
CN102112146A (zh) 2011-06-29
AU2009278385B2 (en) 2015-06-11
MX339277B (es) 2016-05-19
ES2539603T3 (es) 2015-07-02
WO2010016525A1 (ja) 2010-02-11
HUE031343T2 (hu) 2017-07-28
ES2619322T3 (es) 2017-06-26
EP2324842A4 (en) 2012-05-23
MX2011001113A (es) 2011-03-04
RU2011108315A (ru) 2012-09-10
PL2324842T3 (pl) 2015-08-31
US8454968B2 (en) 2013-06-04
CA2732283A1 (en) 2010-02-11
RU2511039C2 (ru) 2014-04-10
AU2009278385A1 (en) 2010-02-11
AU2015210461B2 (en) 2017-07-13
KR20160127146A (ko) 2016-11-02
BRPI0912462B1 (pt) 2022-03-22
AU2015210461A1 (en) 2015-09-03
JP5962739B2 (ja) 2016-08-03
KR20110044854A (ko) 2011-05-02
EP2324842A1 (en) 2011-05-25
PT2324842E (pt) 2015-07-21
EP2324842B1 (en) 2015-03-25
CN103751771A (zh) 2014-04-30
KR102009241B1 (ko) 2019-08-09
JPWO2010016525A1 (ja) 2012-01-26
US20110123492A1 (en) 2011-05-26
PT2837383T (pt) 2017-03-17
EP2837383A1 (en) 2015-02-18
CN102112146B (zh) 2014-03-12
RU2013156620A (ru) 2015-06-27
BR122020027042B1 (pt) 2022-11-08
CN103751771B (zh) 2017-09-08
DK2324842T3 (da) 2015-06-22
PL2837383T3 (pl) 2017-07-31
EP2837383B1 (en) 2016-12-14

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