JP5683265B2 - 補体が関係している障害の予防および処置のためのｃ３ｂ抗体ならびに方法 - Google Patents

補体が関係している障害の予防および処置のためのｃ３ｂ抗体ならびに方法 Download PDF

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JP5683265B2
JP5683265B2 JP2010511295A JP2010511295A JP5683265B2 JP 5683265 B2 JP5683265 B2 JP 5683265B2 JP 2010511295 A JP2010511295 A JP 2010511295A JP 2010511295 A JP2010511295 A JP 2010511295A JP 5683265 B2 JP5683265 B2 JP 5683265B2
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antibody
complement
seq
antigen
disease
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JP2011504872A (ja
JP2011504872A5 (cg-RX-API-DMAC7.html
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ルッカーレン カンパーニュ， メノ ファン
ルッカーレン カンパーニュ， メノ ファン
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Genentech Inc
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
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    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
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    • A61P19/04—Drugs for skeletal disorders for non-specific disorders of the connective tissue
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    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565—Complementarity determining region [CDR]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/567—Framework region [FR]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/81—Packaged device or kit

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  • Diabetes (AREA)
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  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
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  • Heart & Thoracic Surgery (AREA)
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  • Urology & Nephrology (AREA)
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  • Vascular Medicine (AREA)
  • Dermatology (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
JP2010511295A 2007-06-07 2008-06-04 補体が関係している障害の予防および処置のためのｃ３ｂ抗体ならびに方法 Expired - Fee Related JP5683265B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US93372107P 2007-06-07 2007-06-07
US60/933,721 2007-06-07
US5506808P 2008-05-21 2008-05-21
US60/055,068 2008-05-21
PCT/US2008/065771 WO2008154251A2 (en) 2007-06-07 2008-06-04 C3b antibodies and methods for the prevention and treatment of complement- associated disorders

Related Child Applications (1)

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JP2014020001A Division JP5980249B2 (ja) 2007-06-07 2014-02-05 補体が関係している障害の予防および処置のためのｃ３ｂ抗体ならびに方法

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JP2011504872A JP2011504872A (ja) 2011-02-17
JP2011504872A5 JP2011504872A5 (cg-RX-API-DMAC7.html) 2011-06-02
JP5683265B2 true JP5683265B2 (ja) 2015-03-11

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JP2010511295A Expired - Fee Related JP5683265B2 (ja) 2007-06-07 2008-06-04 補体が関係している障害の予防および処置のためのｃ３ｂ抗体ならびに方法
JP2014020001A Expired - Fee Related JP5980249B2 (ja) 2007-06-07 2014-02-05 補体が関係している障害の予防および処置のためのｃ３ｂ抗体ならびに方法
JP2016145975A Pending JP2016204382A (ja) 2007-06-07 2016-07-26 補体が関係している障害の予防および処置のためのｃ３ｂ抗体ならびに方法

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JP2014020001A Expired - Fee Related JP5980249B2 (ja) 2007-06-07 2014-02-05 補体が関係している障害の予防および処置のためのｃ３ｂ抗体ならびに方法
JP2016145975A Pending JP2016204382A (ja) 2007-06-07 2016-07-26 補体が関係している障害の予防および処置のためのｃ３ｂ抗体ならびに方法

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US (2) US8012473B2 (cg-RX-API-DMAC7.html)
EP (1) EP2162470A2 (cg-RX-API-DMAC7.html)
JP (3) JP5683265B2 (cg-RX-API-DMAC7.html)
KR (3) KR20170023212A (cg-RX-API-DMAC7.html)
CN (1) CN101809034B (cg-RX-API-DMAC7.html)
AR (1) AR066916A1 (cg-RX-API-DMAC7.html)
AU (1) AU2008262048B2 (cg-RX-API-DMAC7.html)
BR (1) BRPI0812767A2 (cg-RX-API-DMAC7.html)
CA (1) CA2690124A1 (cg-RX-API-DMAC7.html)
CL (1) CL2008001656A1 (cg-RX-API-DMAC7.html)
IL (1) IL201820A0 (cg-RX-API-DMAC7.html)
MX (1) MX2009013082A (cg-RX-API-DMAC7.html)
PE (1) PE20090416A1 (cg-RX-API-DMAC7.html)
RU (1) RU2473563C2 (cg-RX-API-DMAC7.html)
SG (2) SG182165A1 (cg-RX-API-DMAC7.html)
TW (2) TWI441832B (cg-RX-API-DMAC7.html)
WO (1) WO2008154251A2 (cg-RX-API-DMAC7.html)
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