JP5681861B2 - センサを有する嚥下型カプセルを作成する方法 - Google Patents
センサを有する嚥下型カプセルを作成する方法 Download PDFInfo
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- JP5681861B2 JP5681861B2 JP2011501328A JP2011501328A JP5681861B2 JP 5681861 B2 JP5681861 B2 JP 5681861B2 JP 2011501328 A JP2011501328 A JP 2011501328A JP 2011501328 A JP2011501328 A JP 2011501328A JP 5681861 B2 JP5681861 B2 JP 5681861B2
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- capsule
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/07—Endoradiosondes
- A61B5/073—Intestinal transmitters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
- A61B5/14539—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue for measuring pH
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
- A61B5/1495—Calibrating or testing of in-vivo probes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B2560/00—Constructional details of operational features of apparatus; Accessories for medical measuring apparatus
- A61B2560/02—Operational features
- A61B2560/0223—Operational features of calibration, e.g. protocols for calibrating sensors
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- Health & Medical Sciences (AREA)
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- Physics & Mathematics (AREA)
- Medical Informatics (AREA)
- Surgery (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Pathology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Optics & Photonics (AREA)
- Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
- Medical Preparation Storing Or Oral Administration Devices (AREA)
Description
Claims (12)
- システムであって、当該システムが、
少なくとも1つの開口を有するスタートアップステーション(40)と、
充填されていない電解セルを備える電位差センサを有するカプセルと、
液体電解質を含有する液体電解質容器(46)と、
較正用の緩衝液体を有する1つ又はそれより多くの緩衝液容器(47)と、を有しており、
前記液体電解質容器(46)及び前記緩衝液容器(47)が、単一のパッケージに収容されており、該単一のパッケージは、前記スタートアップステーション(40)の少なくとも1つの開口に受容されるように構成されている、
システム。 - 前記センサは、pHセンサである、
請求項1記載のシステム。 - 前記カプセル、前記電解質容器及び前記緩衝液容器は、単一パッケージにおいて別個にパックされており、前記カプセルと、前記液体電解質容器及び前記緩衝液容器とが、それぞれ離してパックされている、
請求項1記載のシステム。 - 電解セルを有する電位差センサを有する嚥下型カプセルを形成する方法であって、
液体電解質が、液体電解質容器(46)内に収容されており、較正用の緩衝液体が1つ又はそれより多くの緩衝液容器(47)に収容されており、
前記カプセル、液体電解質用容器(46)、及び緩衝液容器(47)が、単一パッケージにパックされており、前記カプセルと、前記液体電解質容器及び前記緩衝液容器とが、それぞれ離してパックされており、
前記カプセルの開梱後に、前記カプセルは、スタートアップステーション(40)に受容され、前記電解セルは、前記電解質で充填され、
前記カプセルは、充填後に、前記電解セルにおける前記電解質を緩衝液体に接触させることによって較正され、前記単一パッケージの一部は、前記スタートアップステーション(40)の少なくとも1つの開口に受容される、
方法。 - 前記電解セルの充填後に、前記スタートアップステーションは前記カプセルを始動させる、
請求項4記載の方法。 - 前記較正段階は、1つ又はそれより多くの追加的な緩衝液体に対して反復される、
請求項4記載の方法。 - 請求項4乃至6のうちいずれか一項記載の方法において使用されるスタートアップステーションであって、
該スタートアップステーションは、嚥下型カプセルを受容するための少なくとも2つの開口を有しており、
該開口のうち少なくとも1つ(41)は、前記カプセルを始動させるための電子スタートアップ回路によって部分的に取り囲まれており、前記開口のうち少なくとも1つ(42)は、液体電解質を含有するための穴であり、該穴は、前記カプセルが前記穴内に挿入されたときに前記カプセル端部の1つ又はそれより多くの通気開口が前記穴の内側に留まるように前記カプセルを受容するよう寸法を定められ、
当該スタートアップステーションは、1つ又はそれより多くの更なる穴(43)を有し、該更なる穴は夫々緩衝液体で少なくとも部分的に充填される、
スタートアップステーション。 - 前記電解質で充填される穴は、該穴の開放端に対向するピストンのピストンチャンバを形成し、該開放端には密封リングが備えられている、
請求項7記載のスタートアップステーション。 - 前記液体電解質が前記電解セルに充填された後に、前記緩衝液体によって前記電位差センサが較正される、
請求項1〜3のいずれか一項に記載のシステム。 - 前記パッケージがシリンジ(50)である、
請求項1に記載のシステム。 - 前記シリンジ(50)が、前記液体電解質及び前記緩衝液を分離する薄膜を含む、
請求項10に記載のシステム。 - フラッシング液体を収容するフラッシング液容器をさらに含む、
請求項11に記載のシステム。
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP08153741 | 2008-03-31 | ||
EP08153741.7 | 2008-03-31 | ||
PCT/IB2009/051215 WO2009122323A1 (en) | 2008-03-31 | 2009-03-24 | Method of preparing a swallowable capsule comprising a sensor |
Publications (2)
Publication Number | Publication Date |
---|---|
JP2011516115A JP2011516115A (ja) | 2011-05-26 |
JP5681861B2 true JP5681861B2 (ja) | 2015-03-11 |
Family
ID=40741173
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2011501328A Expired - Fee Related JP5681861B2 (ja) | 2008-03-31 | 2009-03-24 | センサを有する嚥下型カプセルを作成する方法 |
Country Status (5)
Country | Link |
---|---|
US (1) | US8990018B2 (ja) |
EP (1) | EP2262413B1 (ja) |
JP (1) | JP5681861B2 (ja) |
CN (1) | CN101983029B (ja) |
WO (1) | WO2009122323A1 (ja) |
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WO2012129497A2 (en) * | 2011-03-24 | 2012-09-27 | MEDIMETRICS Personalized Drug Delivery B.V. | Swallowable medication capsule |
DE102011080215B4 (de) | 2011-08-01 | 2013-02-28 | Siemens Aktiengesellschaft | Erfassung von MR-Daten in einem vorbestimmten Bereich |
CN107404651B (zh) * | 2011-09-09 | 2020-03-06 | 株式会社Kt | 用于解码视频信号的方法 |
US10264972B2 (en) * | 2012-05-21 | 2019-04-23 | International Business Machines Corporation | Dispensing drugs from a companion diagnostic linked smart pill |
GB201210439D0 (en) * | 2012-06-13 | 2012-07-25 | Softcell Medicals | Apparatus |
EP3242538A1 (de) * | 2012-08-28 | 2017-11-08 | mb-microtec ag | Verfahren zur herstellung eines hermetischen gehäuses für ein elektronisches gerät |
JP6283677B2 (ja) * | 2012-10-09 | 2018-02-21 | シュトコ・ツェーン・ゲゼルシャフト・ミト・ベシュレンクテル・ハフツング | 外部知能を備える医薬給送カプセル |
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EP3193728B1 (en) * | 2014-09-17 | 2020-07-01 | Mars, Incorporated | Sampling device |
US10478373B2 (en) * | 2016-04-18 | 2019-11-19 | Ankon Medical Technologies (Shanghai) Co., Ltd | In vivo device and method of using the same |
US10500127B2 (en) * | 2016-04-18 | 2019-12-10 | Ankon Medical Technologies (Shanghai) Co., Ltd. | Vivo device and method of using the same |
JP6846701B2 (ja) * | 2017-01-18 | 2021-03-24 | 国立研究開発法人産業技術総合研究所 | pHセンサ及び監視システム |
US11541015B2 (en) | 2017-05-17 | 2023-01-03 | Massachusetts Institute Of Technology | Self-righting systems, methods, and related components |
EP3624778A4 (en) | 2017-05-17 | 2021-03-10 | Massachusetts Institute of Technology | SELF-FIRING ARTICLES |
CA3100710A1 (en) | 2018-05-17 | 2019-11-21 | Massachusetts Institute Of Technology | Systems for electrical stimulation |
US11771829B2 (en) | 2019-02-01 | 2023-10-03 | Massachusetts Institute Of Technology | Systems and methods for liquid injection |
JP2022538345A (ja) | 2019-06-28 | 2022-09-01 | エンディアティックス, インコーポレイテッド | 推進および撮像能力を伴う摂取可能デバイス |
US11541216B2 (en) | 2019-11-21 | 2023-01-03 | Massachusetts Institute Of Technology | Methods for manufacturing tissue interfacing components |
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2009
- 2009-03-24 JP JP2011501328A patent/JP5681861B2/ja not_active Expired - Fee Related
- 2009-03-24 US US12/933,891 patent/US8990018B2/en not_active Expired - Fee Related
- 2009-03-24 EP EP09727142.3A patent/EP2262413B1/en not_active Not-in-force
- 2009-03-24 CN CN200980112018.8A patent/CN101983029B/zh not_active Expired - Fee Related
- 2009-03-24 WO PCT/IB2009/051215 patent/WO2009122323A1/en active Application Filing
Also Published As
Publication number | Publication date |
---|---|
US20110017612A1 (en) | 2011-01-27 |
EP2262413B1 (en) | 2014-02-26 |
CN101983029A (zh) | 2011-03-02 |
CN101983029B (zh) | 2015-01-14 |
US8990018B2 (en) | 2015-03-24 |
JP2011516115A (ja) | 2011-05-26 |
EP2262413A1 (en) | 2010-12-22 |
WO2009122323A1 (en) | 2009-10-08 |
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