JP5661705B2 - ２室式プレフィルドシリンジ用薬液調製装置 - Google Patents
２室式プレフィルドシリンジ用薬液調製装置 Download PDFInfo
- Publication number
- JP5661705B2 JP5661705B2 JP2012198073A JP2012198073A JP5661705B2 JP 5661705 B2 JP5661705 B2 JP 5661705B2 JP 2012198073 A JP2012198073 A JP 2012198073A JP 2012198073 A JP2012198073 A JP 2012198073A JP 5661705 B2 JP5661705 B2 JP 5661705B2
- Authority
- JP
- Japan
- Prior art keywords
- movable wall
- prefilled syringe
- pressing force
- chemical
- space
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- 229940071643 prefilled syringe Drugs 0.000 title claims description 56
- 239000000126 substance Substances 0.000 title claims description 49
- 238000002360 preparation method Methods 0.000 title claims description 41
- 239000000243 solution Substances 0.000 claims description 52
- 239000003814 drug Substances 0.000 claims description 50
- 229940079593 drug Drugs 0.000 claims description 44
- 238000003825 pressing Methods 0.000 claims description 34
- 238000002347 injection Methods 0.000 claims description 23
- 239000007924 injection Substances 0.000 claims description 23
- 239000007788 liquid Substances 0.000 claims description 23
- 239000008155 medical solution Substances 0.000 claims description 5
- 102000018997 Growth Hormone Human genes 0.000 claims description 3
- 108010051696 Growth Hormone Proteins 0.000 claims description 3
- 239000000122 growth hormone Substances 0.000 claims description 3
- 238000005192 partition Methods 0.000 claims description 3
- 238000002156 mixing Methods 0.000 description 17
- 230000007246 mechanism Effects 0.000 description 15
- 230000033001 locomotion Effects 0.000 description 7
- 239000000203 mixture Substances 0.000 description 4
- PPBRXRYQALVLMV-UHFFFAOYSA-N Styrene Chemical compound C=CC1=CC=CC=C1 PPBRXRYQALVLMV-UHFFFAOYSA-N 0.000 description 2
- 230000000740 bleeding effect Effects 0.000 description 2
- 239000003795 chemical substances by application Substances 0.000 description 2
- 229920005556 chlorobutyl Polymers 0.000 description 2
- 238000010586 diagram Methods 0.000 description 2
- 239000011521 glass Substances 0.000 description 2
- 238000004519 manufacturing process Methods 0.000 description 2
- 239000000463 material Substances 0.000 description 2
- 238000000034 method Methods 0.000 description 2
- 239000004033 plastic Substances 0.000 description 2
- 230000001681 protective effect Effects 0.000 description 2
- 229920003051 synthetic elastomer Polymers 0.000 description 2
- 239000005061 synthetic rubber Substances 0.000 description 2
- 229920002725 thermoplastic elastomer Polymers 0.000 description 2
- 102000002265 Human Growth Hormone Human genes 0.000 description 1
- 108010000521 Human Growth Hormone Proteins 0.000 description 1
- 239000000854 Human Growth Hormone Substances 0.000 description 1
- 239000005062 Polybutadiene Substances 0.000 description 1
- 229920002367 Polyisobutene Polymers 0.000 description 1
- 239000003708 ampul Substances 0.000 description 1
- 239000005388 borosilicate glass Substances 0.000 description 1
- 229920005557 bromobutyl Polymers 0.000 description 1
- 229920005549 butyl rubber Polymers 0.000 description 1
- POIUWJQBRNEFGX-XAMSXPGMSA-N cathelicidin Chemical compound C([C@@H](C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)CC)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC=1C=CC=CC=1)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC=1C=CC=CC=1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CO)C(O)=O)NC(=O)[C@H](CC=1C=CC=CC=1)NC(=O)[C@H](CC(O)=O)NC(=O)CNC(=O)[C@H](CC(C)C)NC(=O)[C@@H](N)CC(C)C)C1=CC=CC=C1 POIUWJQBRNEFGX-XAMSXPGMSA-N 0.000 description 1
- 239000002552 dosage form Substances 0.000 description 1
- 238000001035 drying Methods 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 238000001125 extrusion Methods 0.000 description 1
- 238000004108 freeze drying Methods 0.000 description 1
- 230000010354 integration Effects 0.000 description 1
- 229920003049 isoprene rubber Polymers 0.000 description 1
- 229920002857 polybutadiene Polymers 0.000 description 1
- 239000000843 powder Substances 0.000 description 1
- 108090000765 processed proteins & peptides Proteins 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 238000003860 storage Methods 0.000 description 1
- 229920001935 styrene-ethylene-butadiene-styrene Polymers 0.000 description 1
Images
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
- B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
- B65D81/00—Containers, packaging elements, or packages, for contents presenting particular transport or storage problems, or adapted to be used for non-packaging purposes after removal of contents
- B65D81/32—Containers, packaging elements, or packages, for contents presenting particular transport or storage problems, or adapted to be used for non-packaging purposes after removal of contents for packaging two or more different materials which must be maintained separate prior to use in admixture
- B65D81/3255—Containers provided with a piston or a movable bottom, and permitting admixture within the container
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
- A61M5/2066—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically comprising means for injection of two or more media, e.g. by mixing
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/24—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic
- A61M5/2448—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic comprising means for injection of two or more media, e.g. by mixing
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Hematology (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Mechanical Engineering (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
- Medical Preparation Storing Or Oral Administration Devices (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2012198073A JP5661705B2 (ja) | 2011-09-12 | 2012-09-10 | ２室式プレフィルドシリンジ用薬液調製装置 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2011198025 | 2011-09-12 | ||
| JP2011198025 | 2011-09-12 | ||
| JP2012198073A JP5661705B2 (ja) | 2011-09-12 | 2012-09-10 | ２室式プレフィルドシリンジ用薬液調製装置 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2013075154A JP2013075154A (ja) | 2013-04-25 |
| JP5661705B2 true JP5661705B2 (ja) | 2015-01-28 |
Family
ID=47883258
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012198073A Active JP5661705B2 (ja) | 2011-09-12 | 2012-09-10 | ２室式プレフィルドシリンジ用薬液調製装置 |
Country Status (2)
| Country | Link |
|---|---|
| JP (1) | JP5661705B2 (fr) |
| WO (1) | WO2013039028A1 (fr) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103318551A (zh) * | 2013-06-24 | 2013-09-25 | 李和伟 | 一种冻干赋型制剂的包装和递送系统及其制备方法 |
| DE102015206757A1 (de) * | 2015-04-15 | 2016-10-20 | Henkel IP & Holding GmbH | Misch- und Ausgabevorrichtung sowie Verfahren für die Bereitstellung und Applikation eines aus mindestens zwei Komponenten bestehenden Klebstoffes |
| ES2871128T3 (es) * | 2015-09-30 | 2021-10-28 | Kaken Pharma Co Ltd | Dispositivo de jeringa para poner en comunicación dos tipos de sustancias y método para ello |
| PL3397324T3 (pl) | 2015-12-30 | 2022-10-24 | Ascendis Pharma A/S | Automatyczny wstrzykiwacz z układem utrzymywania wkładu |
| EP3397318B1 (fr) | 2015-12-30 | 2021-11-10 | Ascendis Pharma A/S | Injecteur automatique avec mécanisme de tir d'air adaptable |
| PL3397321T3 (pl) | 2015-12-30 | 2023-01-23 | Ascendis Pharma A/S | Automatyczny wstrzykiwacz z regulacją temperatury |
| CA3006638C (fr) | 2015-12-30 | 2024-03-05 | Ascendis Pharma A/S | Injecteur automatique avec securite pour chargeur |
| KR102526705B1 (ko) * | 2017-05-23 | 2023-04-27 | 아센디스 파마 에이에스 | 가변 플런저 힘을 갖는 자동 인젝터 |
| AU2018294519B2 (en) | 2017-06-29 | 2023-10-12 | Ascendis Pharma A/S | Auto injector with reconstitution handling support |
| EP4324501A1 (fr) * | 2021-04-15 | 2024-02-21 | Alteogen, Inc | Seringue pré-remplie remplie d'un médicament liquide à faible dose, et son procédé de préparation |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2003A (en) * | 1841-03-12 | Improvement in horizontal windivhlls | ||
| JPH0780064A (ja) * | 1993-06-28 | 1995-03-28 | Kyowa Shinku Gijutsu Kk | 薬品容器兼注射器における注射筒本体 |
| SE0001894D0 (sv) * | 2000-05-22 | 2000-05-22 | Pharmacia & Upjohn Ab | Medical device |
| WO2004004809A1 (fr) * | 2002-07-02 | 2004-01-15 | Matsushita Electric Industrial Co., Ltd. | Dispositif d'administration automatique medical |
| DE10340586A1 (de) * | 2003-09-03 | 2005-04-07 | Tecpharma Licensing Ag | Abmischvorrichtung für Mehrkammerampulle |
-
2012
- 2012-09-10 WO PCT/JP2012/073024 patent/WO2013039028A1/fr active Application Filing
- 2012-09-10 JP JP2012198073A patent/JP5661705B2/ja active Active
Also Published As
| Publication number | Publication date |
|---|---|
| WO2013039028A1 (fr) | 2013-03-21 |
| JP2013075154A (ja) | 2013-04-25 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP5661705B2 (ja) | ２室式プレフィルドシリンジ用薬液調製装置 | |
| US11058817B2 (en) | Administration apparatus for medical use | |
| ES2677599T3 (es) | Dispositivo de inyección para rellenos de aumento de tejido blando, agentes bioactivos y otros materiales biocompatibles en forma líquida o de gel | |
| CN100462111C (zh) | 医用自动给药器 | |
| EP3035903B1 (fr) | Système de remplissage de seringue et procédé associé | |
| JP6752775B2 (ja) | シリンジホルダ及び薬液投与セット | |
| JP5481009B2 (ja) | 温度測定部付き注射装置 | |
| US20150000784A1 (en) | Filling apparatus for drug containers and method for filling the same | |
| JP2015181869A (ja) | 薬液投与装置 | |
| JP2015181835A (ja) | 薬液投与装置 | |
| WO2023166864A1 (fr) | Dispositif d'administration de médicament liquide, son procédé de commande et système d'administration de médicament liquide | |
| JP2023127492A (ja) | 薬液投与装置及びその制御方法、並びに、薬液投与システム | |
| JP2023127494A (ja) | 薬液投与装置及びその制御方法、並びに、薬液投与システム | |
| KR200460768Y1 (ko) | 일회용 ２성분 혼합형 충전약제 주사기 | |
| EP3622987A1 (fr) | Procédé d'assemblage d'un dispositif d'injection ou de perfusion | |
| JP2018079060A (ja) | 薬剤注入装置 |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| A621 | Written request for application examination |
Free format text: JAPANESE INTERMEDIATE CODE: A621 Effective date: 20120910 |
|
| A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20121004 |
|
| A131 | Notification of reasons for refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A131 Effective date: 20130813 |
|
| A977 | Report on retrieval |
Free format text: JAPANESE INTERMEDIATE CODE: A971007 Effective date: 20130830 |
|
| A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20131009 |
|
| A977 | Report on retrieval |
Free format text: JAPANESE INTERMEDIATE CODE: A971007 Effective date: 20131021 |
|
| A02 | Decision of refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A02 Effective date: 20140513 |
|
| A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20140811 |
|
| A911 | Transfer to examiner for re-examination before appeal (zenchi) |
Free format text: JAPANESE INTERMEDIATE CODE: A911 Effective date: 20140925 |
|
| TRDD | Decision of grant or rejection written | ||
| A01 | Written decision to grant a patent or to grant a registration (utility model) |
Free format text: JAPANESE INTERMEDIATE CODE: A01 Effective date: 20141118 |
|
| A61 | First payment of annual fees (during grant procedure) |
Free format text: JAPANESE INTERMEDIATE CODE: A61 Effective date: 20141203 |
|
| R150 | Certificate of patent or registration of utility model |
Ref document number: 5661705 Country of ref document: JP Free format text: JAPANESE INTERMEDIATE CODE: R150 |
|
| R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
| R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
| R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
| R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
| R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
| R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
| R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |