JP5658137B2 - 統合失調症又は薬物渇望治療用医薬組成物 - Google Patents
統合失調症又は薬物渇望治療用医薬組成物 Download PDFInfo
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- JP5658137B2 JP5658137B2 JP2011505202A JP2011505202A JP5658137B2 JP 5658137 B2 JP5658137 B2 JP 5658137B2 JP 2011505202 A JP2011505202 A JP 2011505202A JP 2011505202 A JP2011505202 A JP 2011505202A JP 5658137 B2 JP5658137 B2 JP 5658137B2
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
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- C07D271/02—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms not condensed with other rings
- C07D271/06—1,2,4-Oxadiazoles; Hydrogenated 1,2,4-oxadiazoles
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06008—Dipeptides with the first amino acid being neutral
- C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
- C07K5/0606—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing heteroatoms not provided for by C07K5/06086 - C07K5/06139, e.g. Ser, Met, Cys, Thr
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- Chemical & Material Sciences (AREA)
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- Health & Medical Sciences (AREA)
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- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Peptides Or Proteins (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Steroid Compounds (AREA)
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| US4538608P | 2008-04-16 | 2008-04-16 | |
| US61/045,386 | 2008-04-16 | ||
| PCT/US2009/040799 WO2009137251A2 (en) | 2008-04-16 | 2009-04-16 | Cysteine and cystine bioisosteres to treat schizophrenia and reduce drug cravings |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
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| JP2014147954A Division JP5892561B2 (ja) | 2008-04-16 | 2014-07-18 | 統合失調症を治療し、薬物渇望を低減するためのシステイン及びシスチンのバイオ同配体 |
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| JP2011518176A JP2011518176A (ja) | 2011-06-23 |
| JP2011518176A5 JP2011518176A5 (enExample) | 2014-04-10 |
| JP5658137B2 true JP5658137B2 (ja) | 2015-01-21 |
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| JP2011505202A Expired - Fee Related JP5658137B2 (ja) | 2008-04-16 | 2009-04-16 | 統合失調症又は薬物渇望治療用医薬組成物 |
| JP2014147954A Expired - Fee Related JP5892561B2 (ja) | 2008-04-16 | 2014-07-18 | 統合失調症を治療し、薬物渇望を低減するためのシステイン及びシスチンのバイオ同配体 |
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| Application Number | Title | Priority Date | Filing Date |
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| JP2014147954A Expired - Fee Related JP5892561B2 (ja) | 2008-04-16 | 2014-07-18 | 統合失調症を治療し、薬物渇望を低減するためのシステイン及びシスチンのバイオ同配体 |
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| Country | Link |
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| US (1) | US20100048587A1 (enExample) |
| EP (1) | EP2265594A2 (enExample) |
| JP (2) | JP5658137B2 (enExample) |
| CA (1) | CA2721433A1 (enExample) |
| WO (1) | WO2009137251A2 (enExample) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2014221815A (ja) * | 2008-04-16 | 2014-11-27 | マーケット ユニバーシティー | 統合失調症を治療し、薬物渇望を低減するためのシステイン及びシスチンのバイオ同配体 |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2011079313A1 (en) * | 2009-12-23 | 2011-06-30 | Map Pharmaceuticals, Inc. | Novel ergoline analogs |
| US8815905B2 (en) * | 2010-03-10 | 2014-08-26 | Promentis Pharmaceuticals, Inc. | Propionic acids, propionic acid esters, and related compounds |
| WO2012177962A1 (en) | 2011-06-23 | 2012-12-27 | Map Pharmaceuticals, Inc. | Novel fluoroergoline analogs |
| CA2859173A1 (en) | 2011-12-19 | 2013-06-27 | Map Pharmaceuticals, Inc. | Novel iso-ergoline derivatives |
| WO2013095708A1 (en) * | 2011-12-21 | 2013-06-27 | Map Pharmaceuticals, Inc. | Novel neuromodulatory compounds |
| US9012640B2 (en) | 2012-06-22 | 2015-04-21 | Map Pharmaceuticals, Inc. | Cabergoline derivatives |
| PL3066089T3 (pl) | 2013-11-08 | 2020-04-30 | Promentis Pharmaceuticals, Inc. | Podstawione pochodne N-Acetylo-L-Cysteiny i związki pokrewne |
| US9193681B1 (en) | 2014-05-30 | 2015-11-24 | Promentis Pharmaceuticals, Inc. | Propionic acids, propionic acid esters, and related compounds |
| JP7128460B2 (ja) * | 2015-06-04 | 2022-08-31 | 国立研究開発法人国立精神・神経医療研究センター | Ｉｌ－６阻害剤を有効成分とする精神疾患治療剤 |
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| TW343965B (en) * | 1994-03-30 | 1998-11-01 | Hoffmann La Roche | Novel mono- and bicyclic DNA gyrase inhibitors |
| AU740782B2 (en) * | 1997-07-25 | 2001-11-15 | Nippon Kayaku Kabushiki Kaisha | Novel compound having effect of promoting neuron differentiation |
| JP2002226457A (ja) * | 2001-02-02 | 2002-08-14 | Ajinomoto Co Inc | 新規シスチン誘導体及び炎症因子活性化抑制剤 |
| DE10138578A1 (de) * | 2001-08-06 | 2003-02-27 | Bayer Ag | Heterocyclylarylsulfonamide |
| SE0301653D0 (sv) * | 2003-06-05 | 2003-06-05 | Astrazeneca Ab | Novel compounds |
| WO2008008380A1 (en) * | 2006-07-12 | 2008-01-17 | Regents Of The University Of Minnesota | Combination therapy for addiction disorders |
| WO2009137251A2 (en) * | 2008-04-16 | 2009-11-12 | Marquette University | Cysteine and cystine bioisosteres to treat schizophrenia and reduce drug cravings |
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2009
- 2009-04-16 WO PCT/US2009/040799 patent/WO2009137251A2/en not_active Ceased
- 2009-04-16 EP EP09743238A patent/EP2265594A2/en not_active Withdrawn
- 2009-04-16 JP JP2011505202A patent/JP5658137B2/ja not_active Expired - Fee Related
- 2009-04-16 US US12/425,063 patent/US20100048587A1/en not_active Abandoned
- 2009-04-16 CA CA2721433A patent/CA2721433A1/en not_active Abandoned
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2014
- 2014-07-18 JP JP2014147954A patent/JP5892561B2/ja not_active Expired - Fee Related
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2014221815A (ja) * | 2008-04-16 | 2014-11-27 | マーケット ユニバーシティー | 統合失調症を治療し、薬物渇望を低減するためのシステイン及びシスチンのバイオ同配体 |
Also Published As
| Publication number | Publication date |
|---|---|
| EP2265594A2 (en) | 2010-12-29 |
| WO2009137251A2 (en) | 2009-11-12 |
| US20100048587A1 (en) | 2010-02-25 |
| CA2721433A1 (en) | 2009-11-12 |
| WO2009137251A3 (en) | 2010-01-14 |
| JP2014221815A (ja) | 2014-11-27 |
| JP2011518176A (ja) | 2011-06-23 |
| JP5892561B2 (ja) | 2016-03-23 |
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