JP5642973B2 - Jak阻害薬として有用なn−複素環式化合物 - Google Patents

Jak阻害薬として有用なn−複素環式化合物 Download PDF

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Publication number
JP5642973B2
JP5642973B2 JP2009554762A JP2009554762A JP5642973B2 JP 5642973 B2 JP5642973 B2 JP 5642973B2 JP 2009554762 A JP2009554762 A JP 2009554762A JP 2009554762 A JP2009554762 A JP 2009554762A JP 5642973 B2 JP5642973 B2 JP 5642973B2
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Japan
Prior art keywords
aliphatic
optionally substituted
ring
compound according
compound
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Japanese (ja)
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JP2010522210A (ja
JP2010522210A5 (enExample
Inventor
ワナメイカー, マリオン
マリオン ワナメイカー,
フランセスコ サリトゥーロ,
フランセスコ サリトゥーロ,
ピアース, アルバート
アルバート ピアース,
アレクサンダー アロノフ,
アレクサンダー アロノフ,
ガブリエル マルティネス−ボテッラ,
ガブリエル マルティネス−ボテッラ,
チーアン ワン,
チーアン ワン,
ルーク ファーマー,
ルーク ファーマー,
マーク レデボア,
マーク レデボア,
ティアンシェン ワン,
ティアンシェン ワン,
ランディー ベシール,
ランディー ベシール,
ブライアン レッドフォード,
ブライアン レッドフォード,
エミリー ポーター,
エミリー ポーター,
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Vertex Pharmaceuticals Inc
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Vertex Pharmaceuticals Inc
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    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
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    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
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JP2009554762A 2007-03-22 2008-03-21 Jak阻害薬として有用なn−複素環式化合物 Expired - Fee Related JP5642973B2 (ja)

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US91946907P 2007-03-22 2007-03-22
US60/919,469 2007-03-22
PCT/US2008/057797 WO2008116139A2 (en) 2007-03-22 2008-03-21 N-heterocyclic compounds useful as inhibitors of janus kinases

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JP2010522210A5 JP2010522210A5 (enExample) 2013-12-19
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US (3) US20100160287A1 (enExample)
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CA2681516A1 (en) 2008-09-25
IL201064A0 (en) 2010-05-17
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