JP5612269B2 - 歯周病マーカー - Google Patents

歯周病マーカー Download PDF

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Publication number
JP5612269B2
JP5612269B2 JP2009107085A JP2009107085A JP5612269B2 JP 5612269 B2 JP5612269 B2 JP 5612269B2 JP 2009107085 A JP2009107085 A JP 2009107085A JP 2009107085 A JP2009107085 A JP 2009107085A JP 5612269 B2 JP5612269 B2 JP 5612269B2
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Japan
Prior art keywords
periodontal disease
autoinducer
collected
bacteria
oral cavity
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JP2009107085A
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English (en)
Japanese (ja)
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JP2010256190A5 (enExample
JP2010256190A (ja
Inventor
初美 惣野
初美 惣野
英剛 藤中
英剛 藤中
純二 中村
純二 中村
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Kao Corp
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Kao Corp
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Publication date
Priority to JP2009107085A priority Critical patent/JP5612269B2/ja
Application filed by Kao Corp filed Critical Kao Corp
Priority to PCT/JP2010/056778 priority patent/WO2010122946A1/ja
Priority to EP10767003.6A priority patent/EP2423683B1/en
Priority to EP13163479.2A priority patent/EP2631648B1/en
Priority to US13/258,700 priority patent/US8293478B2/en
Publication of JP2010256190A publication Critical patent/JP2010256190A/ja
Publication of JP2010256190A5 publication Critical patent/JP2010256190A5/ja
Priority to US13/529,717 priority patent/US8568986B2/en
Application granted granted Critical
Publication of JP5612269B2 publication Critical patent/JP5612269B2/ja
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
    • C12Q1/025—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
    • A61K31/341—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide not condensed with another ring, e.g. ranitidine, furosemide, bufetolol, muscarine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H23/00—Compounds containing boron, silicon or a metal, e.g. chelates or vitamin B12
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
    • C12Q1/18—Testing for antimicrobial activity of a material
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5091—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing the pathological state of an organism
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00—Screening for compounds of potential therapeutic value
    • G01N2500/10—Screening for compounds of potential therapeutic value involving cells
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/18—Dental and oral disorders
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A90/00—Technologies having an indirect contribution to adaptation to climate change
    • Y02A90/10—Information and communication technologies [ICT] supporting adaptation to climate change, e.g. for weather forecasting or climate simulation

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Analytical Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Toxicology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biophysics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Physiology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Public Health (AREA)
  • Cell Biology (AREA)
  • Epidemiology (AREA)
  • Veterinary Medicine (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP2009107085A 2009-04-24 2009-04-24 歯周病マーカー Active JP5612269B2 (ja)

Priority Applications (6)

Application Number Priority Date Filing Date Title
JP2009107085A JP5612269B2 (ja) 2009-04-24 2009-04-24 歯周病マーカー
EP10767003.6A EP2423683B1 (en) 2009-04-24 2010-04-15 Periodontal disease markers.
EP13163479.2A EP2631648B1 (en) 2009-04-24 2010-04-15 Therapeutic target for periodontal disease.
US13/258,700 US8293478B2 (en) 2009-04-24 2010-04-15 Method of using autoinducer-2 as a periodontal disease marker
PCT/JP2010/056778 WO2010122946A1 (ja) 2009-04-24 2010-04-15 歯周病マーカー
US13/529,717 US8568986B2 (en) 2009-04-24 2012-06-21 Method of selecting an agent that improves periodontal disease

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2009107085A JP5612269B2 (ja) 2009-04-24 2009-04-24 歯周病マーカー

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2014011496A Division JP5827704B2 (ja) 2014-01-24 2014-01-24 歯周病マーカー

Publications (3)

Publication Number Publication Date
JP2010256190A JP2010256190A (ja) 2010-11-11
JP2010256190A5 JP2010256190A5 (enExample) 2012-05-17
JP5612269B2 true JP5612269B2 (ja) 2014-10-22

Family

ID=43011063

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2009107085A Active JP5612269B2 (ja) 2009-04-24 2009-04-24 歯周病マーカー

Country Status (4)

Country Link
US (2) US8293478B2 (enExample)
EP (2) EP2631648B1 (enExample)
JP (1) JP5612269B2 (enExample)
WO (1) WO2010122946A1 (enExample)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8663927B2 (en) * 2007-09-10 2014-03-04 University Of Kentucky Research Foundation Systems and methods for diagnosis and monitoring of bacteria-related conditions
JP5318521B2 (ja) * 2007-10-17 2013-10-16 花王株式会社 オートインデューサー−２の定量方法
JP5869323B2 (ja) * 2011-12-01 2016-02-24 花王株式会社 歯周病マーカー
CN102706821B (zh) * 2012-06-15 2014-11-12 广东工业大学 一种食源菌生物被膜形成抑制剂的快速鉴定方法
US9949671B2 (en) 2013-03-13 2018-04-24 Orthoaccel Technologies, Inc. Diagnostic mouthpieces
EP3151733B1 (en) * 2014-06-06 2020-04-15 The Regents Of The University Of Michigan Compositions and methods for characterizing and diagnosing periodontal disease
WO2016095202A1 (en) * 2014-12-19 2016-06-23 The Procter & Gamble Company Gum condition assessment
JP6632800B2 (ja) 2014-12-24 2020-01-22 メディア株式会社 歯周病診断支援装置、歯周病診断支援システム、歯周病診断支援プログラム及び歯周病診断支援方法
JP6480278B2 (ja) * 2015-07-08 2019-03-06 長田産業株式会社 歯肉炎・歯周炎の簡易判定補助方法
MY196578A (en) * 2016-04-05 2023-04-19 Lion Corp Method for Determining Stage of Periodontal Disease
WO2017195268A1 (ja) * 2016-05-10 2017-11-16 株式会社アイシーエレクトロニクス ｍｉＲＮＡをマーカーとする歯周炎検査キット、及び検査方法
JP2021526802A (ja) 2018-06-08 2021-10-11 ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニアＴｈｅ Ｒｅｇｅｎｔｓ Ｏｆ Ｔｈｅ Ｕｎｉｖｅｒｓｉｔｙ Ｏｆ Ｃａｌｉｆｏｒｎｉａ 多株集団制御系および方法
US12594307B2 (en) 2019-12-13 2026-04-07 The Regents Of The University Of California Compositions and methods of using inducible signaling for tunable dynamics in microbial communities

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3165788B2 (ja) 1996-04-17 2001-05-14 株式会社いかがく 歯周病の診断キット
JP2000028608A (ja) 1999-06-28 2000-01-28 Ikagaku:Kk 歯周病の診断キット
US6726898B2 (en) * 2000-11-17 2004-04-27 Gary R. Jernberg Local delivery of agents for disruption and inhibition of bacterial biofilm for treatment of periodontal disease
AUPR209000A0 (en) * 2000-12-14 2001-01-11 Unisearch Limited Regulation of bacterial virulence
US7427408B2 (en) * 2002-06-06 2008-09-23 The Regents Of The University Of California Quorum sensing and biofilm formation
DE10260891A1 (de) * 2002-12-17 2004-07-08 Henkel Kgaa Screening-Verfahren zur Identifikation wirksamer Substanzen gegen Halitosis, Gingivitis oder Parodontitis
JP3599283B1 (ja) * 2003-06-30 2004-12-08 株式会社エーシーバイオテクノロジーズ 歯周炎の発症を判定する方法。
JP2008537885A (ja) * 2005-04-15 2008-10-02 ノース・キャロライナ・ステイト・ユニヴァーシティ 細菌の付着およびストレス耐性を修飾する方法および組成物
US20070172434A1 (en) * 2006-01-24 2007-07-26 Jernberg Gary R Antimicrobial dental materials, restorations, and prostheses
JP2008214296A (ja) 2007-03-06 2008-09-18 Osaka Univ オートインデューサー−２受容体のモデュレーター
EP2155705A4 (en) * 2007-06-08 2012-02-15 Univ Georgia State Res Found COMPOSITIONS FOR REGULATING OR MODULATING QUORUM DETECTION IN BACTERIA, METHODS OF USING THE SAME, AND METHODS OF REGULATING AND MODULATING QUORUM DETECTION IN BACTERIUM
US9150788B2 (en) * 2007-09-18 2015-10-06 Syracuse University Non-amphiphile-based water-in-water emulsion and uses thereof

Also Published As

Publication number Publication date
EP2631648A2 (en) 2013-08-28
EP2423683B1 (en) 2015-03-18
EP2631648B1 (en) 2015-08-12
US20120015397A1 (en) 2012-01-19
JP2010256190A (ja) 2010-11-11
WO2010122946A1 (ja) 2010-10-28
US20120276546A1 (en) 2012-11-01
EP2423683A1 (en) 2012-02-29
EP2631648A3 (en) 2013-12-18
EP2423683A4 (en) 2012-10-03
US8568986B2 (en) 2013-10-29
US8293478B2 (en) 2012-10-23

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