JP5548328B2 - 疾患の処置における細胞毒性物質、薬物プレ増感剤および化学増感剤としてのヒアルロナン - Google Patents

疾患の処置における細胞毒性物質、薬物プレ増感剤および化学増感剤としてのヒアルロナン Download PDF

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JP5548328B2
JP5548328B2 JP2002511783A JP2002511783A JP5548328B2 JP 5548328 B2 JP5548328 B2 JP 5548328B2 JP 2002511783 A JP2002511783 A JP 2002511783A JP 2002511783 A JP2002511783 A JP 2002511783A JP 5548328 B2 JP5548328 B2 JP 5548328B2
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cancer
hyaluronan
administration
chemotherapeutic agent
kit
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JP2004502789A5 (enExample
JP2004502789A (ja
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トレイシー・ブラウン
リチャード・フォックス
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MEDITECK RESEARCH LIMITED
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MEDITECK RESEARCH LIMITED
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0014Skin, i.e. galenical aspects of topical compositions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/337Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • A61K31/4738Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4745Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/525Isoalloxazines, e.g. riboflavins, vitamin B2
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7028Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
    • A61K31/7034Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
    • A61K31/704Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin attached to a condensed carbocyclic ring system, e.g. sennosides, thiocolchicosides, escin, daunorubicin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/726Glycosaminoglycans, i.e. mucopolysaccharides
    • A61K31/728Hyaluronic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/04Antineoplastic agents specific for metastasis

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Dermatology (AREA)
  • Inorganic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
JP2002511783A 2000-07-14 2001-07-13 疾患の処置における細胞毒性物質、薬物プレ増感剤および化学増感剤としてのヒアルロナン Expired - Fee Related JP5548328B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
AUPQ8795A AUPQ879500A0 (en) 2000-07-14 2000-07-14 Hyaluronan as cytotoxic agent, drug presensitizer and chemo-sensitizer in the treatment of disease
AUPQ8795 2000-07-14
PCT/AU2001/000849 WO2002005852A1 (en) 2000-07-14 2001-07-13 Hyaluronan as a cytotoxic agent, drug pre-sensitizer and chemo-sensitizer in the treatment of disease

Related Child Applications (1)

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JP2012123354A Division JP2012162569A (ja) 2000-07-14 2012-05-30 疾患の処置における細胞毒性物質、薬物プレ増感剤および化学増感剤としてのヒアルロナン

Publications (3)

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JP2004502789A JP2004502789A (ja) 2004-01-29
JP2004502789A5 JP2004502789A5 (enExample) 2008-08-28
JP5548328B2 true JP5548328B2 (ja) 2014-07-16

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JP2002511783A Expired - Fee Related JP5548328B2 (ja) 2000-07-14 2001-07-13 疾患の処置における細胞毒性物質、薬物プレ増感剤および化学増感剤としてのヒアルロナン
JP2012123354A Pending JP2012162569A (ja) 2000-07-14 2012-05-30 疾患の処置における細胞毒性物質、薬物プレ増感剤および化学増感剤としてのヒアルロナン

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JP2012123354A Pending JP2012162569A (ja) 2000-07-14 2012-05-30 疾患の処置における細胞毒性物質、薬物プレ増感剤および化学増感剤としてのヒアルロナン

Country Status (10)

Country Link
US (3) US20030180382A1 (enExample)
EP (1) EP1301209A4 (enExample)
JP (2) JP5548328B2 (enExample)
CN (1) CN1388760A (enExample)
AU (1) AUPQ879500A0 (enExample)
CA (1) CA2382560C (enExample)
GB (1) GB2368525B (enExample)
NZ (1) NZ517359A (enExample)
WO (1) WO2002005852A1 (enExample)
ZA (1) ZA200201561B (enExample)

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US20030180382A1 (en) 2003-09-25
US20060263395A1 (en) 2006-11-23
WO2002005852A1 (en) 2002-01-24
NZ517359A (en) 2003-11-28
JP2012162569A (ja) 2012-08-30
CA2382560A1 (en) 2002-01-24
CA2382560C (en) 2011-05-10
EP1301209A1 (en) 2003-04-16
US8287894B2 (en) 2012-10-16
GB0204331D0 (en) 2002-04-10
ZA200201561B (en) 2003-11-25
US20050267069A1 (en) 2005-12-01
AUPQ879500A0 (en) 2000-08-10
CN1388760A (zh) 2003-01-01
GB2368525A (en) 2002-05-08
JP2004502789A (ja) 2004-01-29
US8388993B2 (en) 2013-03-05
GB2368525B (en) 2004-08-11
EP1301209A4 (en) 2005-11-09

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