CA2382560C - Hyaluronan as a cytotoxic agent, drug pre-sensitizer and chemo-sensitizer in the treatment of disease - Google Patents
Hyaluronan as a cytotoxic agent, drug pre-sensitizer and chemo-sensitizer in the treatment of disease Download PDFInfo
- Publication number
- CA2382560C CA2382560C CA2382560A CA2382560A CA2382560C CA 2382560 C CA2382560 C CA 2382560C CA 2382560 A CA2382560 A CA 2382560A CA 2382560 A CA2382560 A CA 2382560A CA 2382560 C CA2382560 C CA 2382560C
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- Prior art keywords
- cancer
- hyaluronan
- chemotherapeutic agent
- use according
- administration
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- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Dermatology (AREA)
- Molecular Biology (AREA)
- Inorganic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Oncology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AUPQ8795A AUPQ879500A0 (en) | 2000-07-14 | 2000-07-14 | Hyaluronan as cytotoxic agent, drug presensitizer and chemo-sensitizer in the treatment of disease |
| AUPQ8795 | 2000-07-14 | ||
| PCT/AU2001/000849 WO2002005852A1 (en) | 2000-07-14 | 2001-07-13 | Hyaluronan as a cytotoxic agent, drug pre-sensitizer and chemo-sensitizer in the treatment of disease |
Publications (2)
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|---|---|
| CA2382560A1 CA2382560A1 (en) | 2002-01-24 |
| CA2382560C true CA2382560C (en) | 2011-05-10 |
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| CA2382560A Expired - Fee Related CA2382560C (en) | 2000-07-14 | 2001-07-13 | Hyaluronan as a cytotoxic agent, drug pre-sensitizer and chemo-sensitizer in the treatment of disease |
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| CA (1) | CA2382560C (enExample) |
| GB (1) | GB2368525B (enExample) |
| NZ (1) | NZ517359A (enExample) |
| WO (1) | WO2002005852A1 (enExample) |
| ZA (1) | ZA200201561B (enExample) |
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| DE60036915T2 (de) | 1999-01-13 | 2008-08-07 | Alchemia Oncology Pty Ltd., Hawthorn | Verwendung von hyaluronan zur herstellung eines medikaments zur erhöhung der wirksamkeit von zytotoxischen arzneimitteln |
| US9066919B2 (en) * | 2000-07-14 | 2015-06-30 | Alchemia Oncology Pty Limited | Hyaluronan as a chemo-sensitizer in the treatment of cancer |
| AUPQ879500A0 (en) * | 2000-07-14 | 2000-08-10 | Meditech Research Limited | Hyaluronan as cytotoxic agent, drug presensitizer and chemo-sensitizer in the treatment of disease |
| US20050042303A1 (en) * | 2001-08-27 | 2005-02-24 | Brown Tracey Jean | Therapeutic protocols |
| WO2004003545A1 (en) * | 2002-07-01 | 2004-01-08 | Tufts University | Methods and compositions for inhibition of multi-drug resistance by hyaluronan oligomers |
| AU2006274509B2 (en) * | 2005-07-27 | 2012-01-19 | Alchemia Oncology Pty Limited | Therapeutic protocols using hyaluronan |
| CN101287475B (zh) * | 2005-09-07 | 2012-11-14 | 阿尔卡米亚肿瘤学股份有限公司 | 包含透明质酸和治疗抗体的治疗组合物以及制药用途 |
| JP2007153766A (ja) * | 2005-12-01 | 2007-06-21 | Toshitsu Kagaku Kenkyusho:Kk | Ｍａｐキナーゼキナーゼキナーゼ遺伝子の発現増強剤 |
| EP2078528B1 (en) | 2006-09-22 | 2013-08-14 | Kochi University | Radiation sensitizer or anti-cancer chemotherapy sensitizer |
| JP5302340B2 (ja) * | 2008-01-30 | 2013-10-02 | カンザス大学 | リンパ管内化学療法薬物担体 |
| TR201816243T4 (tr) * | 2011-01-31 | 2018-11-21 | Lucolas M D Ltd | Aromataz inhibitörlerinin ve antioksidanların kombinasyonları. |
| US9316645B2 (en) | 2011-10-07 | 2016-04-19 | Brown University | Methods, compositions and kits for imaging cells and tissues using nanoparticles and spatial frequency heterodyne imaging |
| US20130236504A1 (en) * | 2012-03-06 | 2013-09-12 | Medical University Of South Carolina | Delivery System for Enhancing Drug Efficacy |
| WO2014015264A1 (en) | 2012-07-20 | 2014-01-23 | Brown University | Functionalized media and methods of making and using therefor |
| EP2712650A1 (en) | 2012-09-27 | 2014-04-02 | F. Hoffmann-La Roche AG | Adapter and drug cartridge alignment device |
| EP2712651A1 (en) | 2012-09-27 | 2014-04-02 | F. Hoffmann-La Roche AG | Venting device for use in ambulatory infusion system |
| TR201905159T4 (tr) | 2013-02-15 | 2019-05-21 | Kortuc Inc | İntratümöral lokal enjeksiyonda ve taşıyıcı olarak hidrojel ile hidrojen peroksidin kontrollü salımı için kullanılacak radyasyon/kemoterapi sensitizörü. |
| CN109528763A (zh) * | 2018-12-29 | 2019-03-29 | 江苏靶标生物医药研究所有限公司 | 顺铂与透明质酸钠的组合物 |
| CN109512825A (zh) * | 2018-12-29 | 2019-03-26 | 江苏靶标生物医药研究所有限公司 | 一种铂类化合物和透明质酸钠的组合物及其应用 |
| US20240058374A1 (en) * | 2021-02-11 | 2024-02-22 | Virginia Commonwealth University | Methods for preventing cancer relapse |
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| ITPD940054A1 (it) | 1994-03-23 | 1995-09-23 | Fidia Advanced Biopolymers Srl | Polisaccaridi solfatati |
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| AU2006274509B2 (en) | 2005-07-27 | 2012-01-19 | Alchemia Oncology Pty Limited | Therapeutic protocols using hyaluronan |
| CN101287475B (zh) | 2005-09-07 | 2012-11-14 | 阿尔卡米亚肿瘤学股份有限公司 | 包含透明质酸和治疗抗体的治疗组合物以及制药用途 |
-
2000
- 2000-07-14 AU AUPQ8795A patent/AUPQ879500A0/en not_active Abandoned
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2001
- 2001-07-13 GB GB0204331A patent/GB2368525B/en not_active Expired - Fee Related
- 2001-07-13 WO PCT/AU2001/000849 patent/WO2002005852A1/en not_active Ceased
- 2001-07-13 JP JP2002511783A patent/JP5548328B2/ja not_active Expired - Fee Related
- 2001-07-13 EP EP01951219A patent/EP1301209A4/en not_active Ceased
- 2001-07-13 CA CA2382560A patent/CA2382560C/en not_active Expired - Fee Related
- 2001-07-13 NZ NZ517359A patent/NZ517359A/en not_active IP Right Cessation
- 2001-07-13 US US10/088,774 patent/US20030180382A1/en not_active Abandoned
- 2001-07-13 CN CN01802357A patent/CN1388760A/zh active Pending
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2002
- 2002-02-25 ZA ZA200201561A patent/ZA200201561B/en unknown
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2005
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2006
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2012
- 2012-05-30 JP JP2012123354A patent/JP2012162569A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| AUPQ879500A0 (en) | 2000-08-10 |
| US8287894B2 (en) | 2012-10-16 |
| EP1301209A1 (en) | 2003-04-16 |
| US20030180382A1 (en) | 2003-09-25 |
| EP1301209A4 (en) | 2005-11-09 |
| JP2012162569A (ja) | 2012-08-30 |
| JP2004502789A (ja) | 2004-01-29 |
| GB2368525B (en) | 2004-08-11 |
| GB0204331D0 (en) | 2002-04-10 |
| CN1388760A (zh) | 2003-01-01 |
| ZA200201561B (en) | 2003-11-25 |
| US8388993B2 (en) | 2013-03-05 |
| WO2002005852A1 (en) | 2002-01-24 |
| US20060263395A1 (en) | 2006-11-23 |
| US20050267069A1 (en) | 2005-12-01 |
| JP5548328B2 (ja) | 2014-07-16 |
| CA2382560A1 (en) | 2002-01-24 |
| GB2368525A (en) | 2002-05-08 |
| NZ517359A (en) | 2003-11-28 |
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