JP5523673B2 - 光電子検出システム - Google Patents

光電子検出システム Download PDF

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Publication number
JP5523673B2
JP5523673B2 JP2007544468A JP2007544468A JP5523673B2 JP 5523673 B2 JP5523673 B2 JP 5523673B2 JP 2007544468 A JP2007544468 A JP 2007544468A JP 2007544468 A JP2007544468 A JP 2007544468A JP 5523673 B2 JP5523673 B2 JP 5523673B2
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JP
Japan
Prior art keywords
cells
emitter
cell
sample
antigen
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
JP2007544468A
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English (en)
Japanese (ja)
Other versions
JP2008522195A5 (enExample
JP2008522195A (ja
Inventor
ショーベル，エリック，ディー．
ハーパー，ジェームス，ディー．
ペトロヴィック，マーサ，エス．
ナーギ，フランシス，イー．
ライダー，トッド，エイチ．
ホーガン，クリスティン，イー．
マシューズ，リチャード，エイチ．
ラシリグノラ，ジョセフ
ヘネシー，マーク
ヴィアン，トリナ，アール．
ジョセフ，ローズ，エム．
ウタロ，レイモンド
ベリー，ショーン
ホリス，マーク，エイ．
ジョンソン，ベルナデット
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Massachusetts Institute of Technology
Original Assignee
Massachusetts Institute of Technology
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Massachusetts Institute of Technology filed Critical Massachusetts Institute of Technology
Publication of JP2008522195A publication Critical patent/JP2008522195A/ja
Publication of JP2008522195A5 publication Critical patent/JP2008522195A5/ja
Application granted granted Critical
Publication of JP5523673B2 publication Critical patent/JP5523673B2/ja
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/5302—Apparatus specially adapted for immunological test procedures
    • G01N33/5304—Reaction vessels, e.g. agglutination plates
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/6428—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M1/00—Apparatus for enzymology or microbiology
    • C12M1/34—Measuring or testing with condition measuring or sensing means, e.g. colony counters
    • C12M1/3446—Photometry, spectroscopy, laser technology
    • C12M1/3461—Bio- or chemi-luminescence
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M1/00—Apparatus for enzymology or microbiology
    • C12M1/34—Measuring or testing with condition measuring or sensing means, e.g. colony counters
    • C12M1/3446—Photometry, spectroscopy, laser technology
    • C12M1/3476—Fluorescence spectroscopy
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6816—Hybridisation assays characterised by the detection means
    • C12Q1/6825—Nucleic acid detection involving sensors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/645—Specially adapted constructive features of fluorimeters
    • G01N21/6452—Individual samples arranged in a regular 2D-array, e.g. multiwell plates
    • G01N21/6454—Individual samples arranged in a regular 2D-array, e.g. multiwell plates using an integrated detector array
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/582—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with fluorescent label

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • General Engineering & Computer Science (AREA)
  • Optics & Photonics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Cell Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Food Science & Technology (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Biophysics (AREA)
  • Sustainable Development (AREA)
  • Biodiversity & Conservation Biology (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Geophysics And Detection Of Objects (AREA)
  • Radar Systems Or Details Thereof (AREA)
JP2007544468A 2004-12-01 2005-11-30 光電子検出システム Expired - Lifetime JP5523673B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US11/001,583 2004-12-01
US11/001,583 US7422860B2 (en) 2001-02-07 2004-12-01 Optoelectronic detection system
PCT/US2005/043343 WO2007046825A2 (en) 2004-12-01 2005-11-30 Optoelectronic detection system

Publications (3)

Publication Number Publication Date
JP2008522195A JP2008522195A (ja) 2008-06-26
JP2008522195A5 JP2008522195A5 (enExample) 2009-01-22
JP5523673B2 true JP5523673B2 (ja) 2014-06-18

Family

ID=37903963

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2007544468A Expired - Lifetime JP5523673B2 (ja) 2004-12-01 2005-11-30 光電子検出システム

Country Status (9)

Country Link
US (4) US7422860B2 (enExample)
EP (1) EP1831404B1 (enExample)
JP (1) JP5523673B2 (enExample)
CN (1) CN101111605B (enExample)
AT (1) ATE466108T1 (enExample)
AU (1) AU2005337484B2 (enExample)
CA (1) CA2588787A1 (enExample)
DE (1) DE602005020978D1 (enExample)
WO (1) WO2007046825A2 (enExample)

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US6248542B1 (en) 1997-12-09 2001-06-19 Massachusetts Institute Of Technology Optoelectronic sensor
US7422860B2 (en) * 2001-02-07 2008-09-09 Massachusetts Institute Of Technology Optoelectronic detection system
DE60216051T2 (de) * 2001-02-07 2007-06-28 Massachusetts Institute Of Technology, Cambridge Optoelektronisches nachweissystem
US8216797B2 (en) * 2001-02-07 2012-07-10 Massachusetts Institute Of Technology Pathogen detection biosensor
AT500427B1 (de) * 2002-05-29 2009-02-15 Anagnostics Bioanalysis Gmbh Vorrichtung zur analyse von bestandteilen einer probe
AT502549B1 (de) * 2005-10-07 2007-06-15 Anagnostics Bioanalysis Gmbh Vorrichtung zur analyse von flüssigen proben
AU2006350038B2 (en) * 2005-11-30 2011-09-15 Massachusetts Institute Of Technology Pathogen detection biosensor
US20090270269A1 (en) * 2008-04-28 2009-10-29 Ashok Kumar Nano-scale fluoro-biosensors exhibiting a low false alarm rate for rapid detection of biological contaminants
JP5571294B2 (ja) * 2008-05-14 2014-08-13 旭川ポートリー株式会社 培養装置および培養方法
CN102245771B (zh) * 2008-12-16 2013-04-10 诺瓦提斯公司 酵母展示系统
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US8955368B2 (en) 2011-09-21 2015-02-17 Massachusetts Institute Of Technology Apparatus and method for aerosol collection and fluid analysis
US9023640B2 (en) * 2011-12-13 2015-05-05 Fundamental Solutions Corporation Device for rapid detection of infectious agents
EP2972333B1 (en) 2013-03-11 2018-09-19 The University of Toledo A biosensor device to target analytes in situ, in vivo, and/or in real time, and methods of making and using the same
JP6161072B2 (ja) * 2013-12-26 2017-07-12 国立研究開発法人産業技術総合研究所 多チャンネル式化学発光計測システム
GB201600315D0 (en) * 2015-08-13 2016-02-24 Gen Electric Heatseal sampling
CN108305912B (zh) * 2017-01-11 2024-03-26 中国科学院上海微系统与信息技术研究所 具有波长选择性的石墨烯仿生光探测器及其制备方法
KR102016131B1 (ko) * 2017-04-17 2019-10-21 (주)레보스케치 원심력을 이용한 디지털 pcr 장치 및 방법
CN111534419A (zh) * 2020-03-23 2020-08-14 湖南大学 呼吸道微生物快速检测系统及方法
AU2022267355A1 (en) 2021-04-30 2023-10-19 Root Applied Sciences Inc. Device for collecting material from air
CN114544726B (zh) * 2022-02-21 2024-05-03 浙江理工大学 一种丝素蛋白检测用pn型纤维状光电探测器的制备方法
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WO2025137402A1 (en) * 2023-12-19 2025-06-26 Enquyst Technologies Inc. Multichannel optical switch for in-line spectroscopic compound analysis

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Also Published As

Publication number Publication date
EP1831404B1 (en) 2010-04-28
US8835127B2 (en) 2014-09-16
US9494579B2 (en) 2016-11-15
HK1108468A1 (en) 2008-05-09
CA2588787A1 (en) 2007-04-26
US20120135404A1 (en) 2012-05-31
WO2007046825A9 (en) 2007-06-21
US8067184B2 (en) 2011-11-29
US20080166705A1 (en) 2008-07-10
US7422860B2 (en) 2008-09-09
AU2005337484A1 (en) 2007-04-26
JP2008522195A (ja) 2008-06-26
WO2007046825A3 (en) 2007-07-26
AU2005337484B2 (en) 2010-04-29
ATE466108T1 (de) 2010-05-15
WO2007046825A2 (en) 2007-04-26
CN101111605A (zh) 2008-01-23
US20150050723A1 (en) 2015-02-19
EP1831404A2 (en) 2007-09-12
DE602005020978D1 (de) 2010-06-10
CN101111605B (zh) 2013-04-03
US20100041031A1 (en) 2010-02-18

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