JP5488594B2 - プリンリボヌクレオシド及びリボヌクレオチドの製造方法 - Google Patents

プリンリボヌクレオシド及びリボヌクレオチドの製造方法 Download PDF

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JP5488594B2
JP5488594B2 JP2011513790A JP2011513790A JP5488594B2 JP 5488594 B2 JP5488594 B2 JP 5488594B2 JP 2011513790 A JP2011513790 A JP 2011513790A JP 2011513790 A JP2011513790 A JP 2011513790A JP 5488594 B2 JP5488594 B2 JP 5488594B2
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gene
strain
pcr
seq
purine
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JP2012503973A5 (https=
JP2012503973A (ja
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セルゲイ ヴィクトロヴィッチ グロンスキー
ドミトリ ヴラジミロヴィッチ ロマネンコフ
ナタリア パヴロヴナ ザカタエヴァ
貴之 浅原
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Ajinomoto Co Inc
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Ajinomoto Co Inc
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/88—Lyases (4.)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/26—Preparation of nitrogen-containing carbohydrates
    • C12P19/28—N-glycosides
    • C12P19/30—Nucleotides
    • C12P19/32—Nucleotides having a condensed ring system containing a six-membered ring having two N-atoms in the same ring, e.g. purine nucleotides, nicotineamide-adenine dinucleotide
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/26—Preparation of nitrogen-containing carbohydrates
    • C12P19/28—N-glycosides
    • C12P19/30—Nucleotides
    • C12P19/34—Polynucleotides, e.g. nucleic acids, oligoribonucleotides

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  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
JP2011513790A 2008-09-30 2009-09-30 プリンリボヌクレオシド及びリボヌクレオチドの製造方法 Expired - Fee Related JP5488594B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
RU2008138616 2008-09-30
RU2008138616/10A RU2422510C2 (ru) 2008-09-30 2008-09-30 Способ получения пуриновых рибонуклеозидов и рибонуклеотидов
PCT/JP2009/067447 WO2010038903A1 (en) 2008-09-30 2009-09-30 A method for producing purine ribonucleosides and ribonucleotides

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JP2012503973A JP2012503973A (ja) 2012-02-16
JP2012503973A5 JP2012503973A5 (https=) 2012-08-02
JP5488594B2 true JP5488594B2 (ja) 2014-05-14

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JP2011513790A Expired - Fee Related JP5488594B2 (ja) 2008-09-30 2009-09-30 プリンリボヌクレオシド及びリボヌクレオチドの製造方法

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JP (1) JP5488594B2 (https=)
CN (1) CN102171346B (https=)
RU (1) RU2422510C2 (https=)
WO (1) WO2010038903A1 (https=)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103150487B (zh) * 2012-11-29 2016-05-11 扬州大学 一种构建鸡肌肉肌苷酸合成途径相关关键酶基因网络调控方法
US20160017339A1 (en) * 2013-03-14 2016-01-21 The Regents Of The University Of California Non-co2 evolving metabolic pathway for chemical production
US9518278B2 (en) 2013-03-14 2016-12-13 The Regents Of The University Of California Recombinant microorganisms having a methanol elongation cycle (MEC)
CN103146786A (zh) * 2013-03-25 2013-06-12 天津科技大学 一种采用梯度pH顺序控制发酵生产腺苷的方法
RU2542387C1 (ru) * 2013-09-27 2015-02-20 Федеральное государственное унитарное предприятие "Государственный научно-исследовательский институт генетики и селекции промышленных микроорганизмов" (ФГУП "ГосНИИгенетика") БАКТЕРИЯ Bacillus subtilis, ПРОДУЦИРУЮЩАЯ 5`-АМИНОИМИДАЗОЛ-4-КАРБОКСАМИДРИБОЗИД (АИКАР), И СПОСОБ МИКРОБИОЛОГИЧЕСКОГО СИНТЕЗА АИКАР ПУТЕМ КУЛЬТИВИРОВАНИЯ ТАКОЙ БАКТЕРИИ
CN105670979B (zh) * 2016-04-26 2019-03-26 南京工业大学 一种核苷磷酸化酶、编码基因及其高产菌株和应用
EP3861109A1 (en) 2018-10-05 2021-08-11 Ajinomoto Co., Inc. Method for producing target substance by bacterial fermentation
CN112574934B (zh) * 2020-10-12 2022-05-06 廊坊梅花生物技术开发有限公司 高产鸟苷的工程菌及其构建方法与应用
CN112592881B (zh) * 2021-02-25 2021-06-11 中国科学院天津工业生物技术研究所 用于高效外源蛋白表达和高密度培养的工程枯草芽孢杆菌
CN115725486B (zh) * 2022-08-18 2025-07-22 江南大学 一种利用甲醇为碳源的苏云金芽孢杆菌及其应用
CN115851855A (zh) 2022-08-24 2023-03-28 凯莱英医药集团（天津）股份有限公司 酶催化合成嘌呤核苷的方法及组合物

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2002017351A (ja) * 2000-07-07 2002-01-22 Ajinomoto Co Inc ホスホヘキシュロイソメラーゼ及びその遺伝子
US7326546B2 (en) * 2005-03-10 2008-02-05 Ajinomoto Co., Inc. Purine-derived substance-producing bacterium and a method for producing purine-derived substance
RU2365622C2 (ru) * 2006-12-22 2009-08-27 Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" (ЗАО АГРИ) СПОСОБ ПРОДУКЦИИ ПУРИНОВЫХ НУКЛЕОЗИДОВ И НУКЛЕОТИДОВ МЕТОДОМ ФЕРМЕНТАЦИИ С ИСПОЛЬЗОВАНИЕМ БАКТЕРИЙ, ПРИНАДЛЕЖАЩИХ К РОДУ Escherichia ИЛИ Bacillus

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Publication number Publication date
RU2422510C2 (ru) 2011-06-27
CN102171346B (zh) 2014-09-03
RU2008138616A (ru) 2010-04-10
WO2010038903A1 (en) 2010-04-08
CN102171346A (zh) 2011-08-31
JP2012503973A (ja) 2012-02-16

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