JP5479332B2 - 癌の診断方法および治療方法 - Google Patents
癌の診断方法および治療方法 Download PDFInfo
- Publication number
- JP5479332B2 JP5479332B2 JP2010512384A JP2010512384A JP5479332B2 JP 5479332 B2 JP5479332 B2 JP 5479332B2 JP 2010512384 A JP2010512384 A JP 2010512384A JP 2010512384 A JP2010512384 A JP 2010512384A JP 5479332 B2 JP5479332 B2 JP 5479332B2
- Authority
- JP
- Japan
- Prior art keywords
- rrm1
- expression
- level
- patients
- tumor
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
- C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/15—Medicinal preparations ; Physical properties thereof, e.g. dissolubility
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/158—Expression markers
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Engineering & Computer Science (AREA)
- Pathology (AREA)
- Immunology (AREA)
- Analytical Chemistry (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Hospice & Palliative Care (AREA)
- Oncology (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- General Physics & Mathematics (AREA)
- Food Science & Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US94415707P | 2007-06-15 | 2007-06-15 | |
| US60/944,157 | 2007-06-15 | ||
| US3955508P | 2008-03-26 | 2008-03-26 | |
| US61/039,555 | 2008-03-26 | ||
| PCT/US2008/066918 WO2008157353A1 (en) | 2007-06-15 | 2008-06-13 | Methods of diagnosing and treating cancer |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2010530746A JP2010530746A (ja) | 2010-09-16 |
| JP2010530746A5 JP2010530746A5 (enExample) | 2012-05-24 |
| JP5479332B2 true JP5479332B2 (ja) | 2014-04-23 |
Family
ID=40156627
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010512384A Expired - Fee Related JP5479332B2 (ja) | 2007-06-15 | 2008-06-13 | 癌の診断方法および治療方法 |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US20090017012A1 (enExample) |
| EP (1) | EP2171086B1 (enExample) |
| JP (1) | JP5479332B2 (enExample) |
| KR (1) | KR20100044780A (enExample) |
| CN (1) | CN101815793A (enExample) |
| AU (1) | AU2008266048A1 (enExample) |
| BR (1) | BRPI0813364A2 (enExample) |
| CA (1) | CA2690865A1 (enExample) |
| ES (1) | ES2401475T3 (enExample) |
| MX (1) | MX2009013646A (enExample) |
| RU (1) | RU2010101093A (enExample) |
| WO (1) | WO2008157353A1 (enExample) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9605657B2 (en) | 2009-10-15 | 2017-03-28 | Sumitomo Electric Industries, Ltd. | Electric power generation system |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2008541701A (ja) * | 2005-05-04 | 2008-11-27 | ユニヴァーシティ オブ サウス フロリダ | がんの対象における処置応答の予測 |
| US8768629B2 (en) * | 2009-02-11 | 2014-07-01 | Caris Mpi, Inc. | Molecular profiling of tumors |
| RU2008146868A (ru) | 2006-05-18 | 2010-06-27 | Кэрис МПИ, Инк.445 Норт Фифс Стрит, 3-ий Флор, Феникс, Аризона 85004, США (US) | Система и способ определения персонализированого медицинского вмешательства при болезненном состоянии |
| GB2463401B (en) * | 2008-11-12 | 2014-01-29 | Caris Life Sciences Luxembourg Holdings S A R L | Characterizing prostate disorders by analysis of microvesicles |
| CN103237901B (zh) | 2010-03-01 | 2016-08-03 | 卡里斯生命科学瑞士控股有限责任公司 | 用于治疗诊断的生物标志物 |
| MX364637B (es) | 2010-03-29 | 2019-05-03 | Abraxis Bioscience Llc Star | Platino y nanopartículas que incluyen placlitaxel/albúmina para usarse en el trartamiento de nsclc. |
| MX369728B (es) | 2010-03-29 | 2019-11-20 | Abraxis Bioscience Llc | Métodos para mejorar suministro de fármacos y efectividad de agentes terapéuticos. |
| EP2556172A4 (en) | 2010-04-06 | 2013-10-30 | Caris Life Sciences Luxembourg Holdings | CIRCULATING BIOMARKERS FOR DISEASES |
| KR101602532B1 (ko) * | 2013-08-29 | 2016-03-11 | 경북대학교 산학협력단 | 위암의 재발 가능성 예측을 위한 정보제공 방법 |
| EP3396573A4 (en) * | 2015-10-26 | 2019-08-28 | Cipherome | METHOD AND SYSTEM FOR SELECTING AN INDIVIDUALLY ADJUSTED MEDICAMENT WITH THE INFORMATION OF THE VARIATIONS OF A GENOMIC NUCLEOTIDE SEQUENCE AND SURVIVAL INFORMATION OF A CANCER PATIENTS |
| WO2022011207A1 (en) * | 2020-07-10 | 2022-01-13 | Progenics Pharmaceutical, Inc | Methods of making prostate cancer treatment decisions |
| CN113957145B (zh) * | 2021-10-19 | 2023-09-26 | 中国医学科学院肿瘤医院 | m6A相关lncRNA在预测小细胞肺癌预后和化疗反应的应用 |
| CN114564622B (zh) * | 2022-03-03 | 2025-07-25 | 苏州良医汇网络科技有限公司 | 一种tnm分期表录入系统的方法、装置以及设备 |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5705336A (en) * | 1995-03-07 | 1998-01-06 | The United States Of America As Represented By The Department Of Health And Human Services | Assay for sensitivity of tumors to DNA-platinating chemotherapy |
| US20020090642A1 (en) * | 1995-12-11 | 2002-07-11 | Patrick G. Johnston | Methods for determining the prognosis of breast cancer using antibodies specific for thymidylate synthase |
| US6416987B1 (en) * | 1997-02-04 | 2002-07-09 | Sloan Kettering Institute For Cancer Research | Mutants of thymidylate synthase and uses thereof |
| US6087489A (en) * | 1998-06-02 | 2000-07-11 | Isis Pharmaceuticals Inc. | Antisense oligonucleotide modulation of human thymidylate synthase expression |
| EP1191096B1 (en) * | 1999-06-28 | 2011-10-12 | Yusuke Nakamura | Ovel protein and dna thereof |
| US6248535B1 (en) * | 1999-12-20 | 2001-06-19 | University Of Southern California | Method for isolation of RNA from formalin-fixed paraffin-embedded tissue specimens |
| US6582919B2 (en) * | 2001-06-11 | 2003-06-24 | Response Genetics, Inc. | Method of determining epidermal growth factor receptor and HER2-neu gene expression and correlation of levels thereof with survival rates |
| US6518416B1 (en) * | 2000-12-01 | 2003-02-11 | Response Genetics, Inc. | Method of determining a chemotherapeutic regimen based on ERCC1 expression |
| US7049059B2 (en) * | 2000-12-01 | 2006-05-23 | Response Genetics, Inc. | Method of determining a chemotherapeutic regimen based on ERCC1 and TS expression |
| US6602670B2 (en) * | 2000-12-01 | 2003-08-05 | Response Genetics, Inc. | Method of determining a chemotherapeutic regimen based on ERCC1 expression |
| US6956111B2 (en) * | 2001-03-02 | 2005-10-18 | Response Genetics, Inc. | Method of determining dihydropyrimidine dehydrogenase gene expression |
| US6686155B2 (en) * | 2001-06-14 | 2004-02-03 | Response Genetics, Inc. | Method of determining a chemotherapeutic regimen based on glutathione-S-transferase pi expression |
| WO2004031408A1 (en) * | 2002-09-30 | 2004-04-15 | F.Hoffmann-La Roche Ag | Oligonucleotides for genotyping thymidylate synthase gene |
| KR20060120063A (ko) * | 2003-09-29 | 2006-11-24 | 패스워크 인포메틱스 아이엔씨 | 생물학적 특징의 탐지 시스템 및 생물학적 특징 탐지 방법 |
| JP2008541701A (ja) * | 2005-05-04 | 2008-11-27 | ユニヴァーシティ オブ サウス フロリダ | がんの対象における処置応答の予測 |
-
2008
- 2008-06-13 KR KR1020107000955A patent/KR20100044780A/ko not_active Withdrawn
- 2008-06-13 RU RU2010101093/10A patent/RU2010101093A/ru not_active Application Discontinuation
- 2008-06-13 ES ES08771019T patent/ES2401475T3/es active Active
- 2008-06-13 EP EP08771019A patent/EP2171086B1/en not_active Not-in-force
- 2008-06-13 CN CN200880102571A patent/CN101815793A/zh active Pending
- 2008-06-13 JP JP2010512384A patent/JP5479332B2/ja not_active Expired - Fee Related
- 2008-06-13 AU AU2008266048A patent/AU2008266048A1/en not_active Abandoned
- 2008-06-13 MX MX2009013646A patent/MX2009013646A/es not_active Application Discontinuation
- 2008-06-13 US US12/139,134 patent/US20090017012A1/en not_active Abandoned
- 2008-06-13 BR BRPI0813364-6A2A patent/BRPI0813364A2/pt not_active IP Right Cessation
- 2008-06-13 CA CA2690865A patent/CA2690865A1/en not_active Abandoned
- 2008-06-13 WO PCT/US2008/066918 patent/WO2008157353A1/en not_active Ceased
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9605657B2 (en) | 2009-10-15 | 2017-03-28 | Sumitomo Electric Industries, Ltd. | Electric power generation system |
Also Published As
| Publication number | Publication date |
|---|---|
| RU2010101093A (ru) | 2011-07-20 |
| CA2690865A1 (en) | 2008-12-24 |
| ES2401475T3 (es) | 2013-04-19 |
| EP2171086A1 (en) | 2010-04-07 |
| EP2171086A4 (en) | 2010-10-13 |
| MX2009013646A (es) | 2010-03-30 |
| KR20100044780A (ko) | 2010-04-30 |
| US20090017012A1 (en) | 2009-01-15 |
| AU2008266048A1 (en) | 2008-12-24 |
| WO2008157353A1 (en) | 2008-12-24 |
| EP2171086B1 (en) | 2012-12-19 |
| CN101815793A (zh) | 2010-08-25 |
| JP2010530746A (ja) | 2010-09-16 |
| BRPI0813364A2 (pt) | 2014-12-30 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP5479332B2 (ja) | 癌の診断方法および治療方法 | |
| EP2527460B1 (en) | Methods for prediction of clinical outcome to epidermal growth factor receptor inhibitors by cancer patients | |
| JP6900314B2 (ja) | 膀胱癌の治療、診断、及び予後判定方法 | |
| Ilson et al. | A phase 2 trial of erlotinib in patients with previously treated squamous cell and adenocarcinoma of the esophagus | |
| US10456470B2 (en) | Diagnostic methods and compositions for treatment of glioblastoma | |
| US10208355B2 (en) | Method of treatment for glioblastoma by administering a VEGF antagonist | |
| JP2012196235A (ja) | がんの対象における処置応答の予測 | |
| US20170166973A1 (en) | Nucleic acid biomarker and use thereof | |
| JP2011500046A (ja) | Et−743治療のための予後分子マーカー | |
| JP7324769B2 (ja) | 腫瘍細胞中のRAD51 fociの検出に基づく方法 | |
| CN102099493A (zh) | 用于预测对抗癌疗法的反应性的组合方法 | |
| HK1144309A (en) | Methods of diagnosing and treating cancer | |
| Hager | Prevalence and clinical outcomes for patients with ALK-positive resected stage I to III adenocarcinoma: results from the European Thoracic Oncology Platform Lungscape Project | |
| HK40012059B (en) | Methods for diagnosing and treating cancer by means of the expression status and mutational status of nrf2 and downstream target genes of said gene. | |
| HK1141053A (en) | Predicting treatment response in cancer subjects |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20110525 |
|
| A621 | Written request for application examination |
Free format text: JAPANESE INTERMEDIATE CODE: A621 Effective date: 20110525 |
|
| A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20120321 |
|
| A131 | Notification of reasons for refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A131 Effective date: 20130228 |
|
| A601 | Written request for extension of time |
Free format text: JAPANESE INTERMEDIATE CODE: A601 Effective date: 20130529 |
|
| A602 | Written permission of extension of time |
Free format text: JAPANESE INTERMEDIATE CODE: A602 Effective date: 20130605 |
|
| A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20130827 |
|
| TRDD | Decision of grant or rejection written | ||
| A01 | Written decision to grant a patent or to grant a registration (utility model) |
Free format text: JAPANESE INTERMEDIATE CODE: A01 Effective date: 20140131 |
|
| A61 | First payment of annual fees (during grant procedure) |
Free format text: JAPANESE INTERMEDIATE CODE: A61 Effective date: 20140212 |
|
| R150 | Certificate of patent or registration of utility model |
Ref document number: 5479332 Country of ref document: JP Free format text: JAPANESE INTERMEDIATE CODE: R150 |
|
| LAPS | Cancellation because of no payment of annual fees |