JP5465656B2 - 調節物質を同定するための方法 - Google Patents
調節物質を同定するための方法 Download PDFInfo
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- JP5465656B2 JP5465656B2 JP2010500047A JP2010500047A JP5465656B2 JP 5465656 B2 JP5465656 B2 JP 5465656B2 JP 2010500047 A JP2010500047 A JP 2010500047A JP 2010500047 A JP2010500047 A JP 2010500047A JP 5465656 B2 JP5465656 B2 JP 5465656B2
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
- A23L27/00—Spices; Flavouring agents or condiments; Artificial sweetening agents; Table salts; Dietetic salt substitutes; Preparation or treatment thereof
- A23L27/30—Artificial sweetening agents
- A23L27/33—Artificial sweetening agents containing sugars or derivatives
- A23L27/37—Halogenated sugars
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
- A23L27/00—Spices; Flavouring agents or condiments; Artificial sweetening agents; Table salts; Dietetic salt substitutes; Preparation or treatment thereof
- A23L27/84—Flavour masking or reducing agents
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
- A23L27/00—Spices; Flavouring agents or condiments; Artificial sweetening agents; Table salts; Dietetic salt substitutes; Preparation or treatment thereof
- A23L27/86—Addition of bitterness inhibitors
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
- C12Q1/025—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
Landscapes
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- Genetics & Genomics (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Peptides Or Proteins (AREA)
- Investigating Or Analysing Biological Materials (AREA)
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| US60/962,549 | 2007-07-30 | ||
| PCT/CH2008/000134 WO2008119195A1 (en) | 2007-03-30 | 2008-03-27 | Methods to identify modulators |
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| US8546085B2 (en) | 2008-06-13 | 2013-10-01 | Givaudan Sa | Methods of identifying modulators of the bitter taste receptor TAS2R44 |
| US8603762B2 (en) | 2008-08-07 | 2013-12-10 | Givaudan Sa | Methods to identify modulators of the interaction between dextromethorphan and the bitter taste receptor TAS2R46 |
| WO2010088633A2 (en) * | 2009-02-02 | 2010-08-05 | Chromocell Corporation | Novel cell lines and methods |
| SG11201401268RA (en) | 2011-10-20 | 2014-05-29 | Chromocell Corp | Assays for identifying compounds that modulate bitter taste |
| WO2013072332A1 (en) | 2011-11-14 | 2013-05-23 | Givaudan Sa | Methods of using antagonists of bitter taste receptors |
| US9169311B2 (en) | 2013-03-15 | 2015-10-27 | Applied Food Biotechnology, Inc. | Feline bitter taste receptors and methods |
| ES2797547T3 (es) | 2013-03-15 | 2020-12-02 | Applied Food Biotech Inc | Receptores del sabor amargo felino y métodos. |
| WO2014176336A1 (en) | 2013-04-24 | 2014-10-30 | Chromocell Corporation | Assays for identifying compounds that modulate bitter taste |
| PL2994482T3 (pl) * | 2013-05-10 | 2020-06-01 | Pepsico, Inc. | Test internalizacji receptora smaku |
| HK1218301A1 (zh) | 2013-05-10 | 2017-02-10 | 百事可乐公司 | 作為鑒別潛在味覺調節劑的模型的細胞 |
| CN104713927A (zh) * | 2015-03-16 | 2015-06-17 | 常州大学 | 一种检测食品中三氯蔗糖的电化学方法 |
| US20180372721A1 (en) * | 2015-07-28 | 2018-12-27 | Mars, Incorporated | Screening methods using canine t2r receptors and pet food products and compositions identified using the same |
| EP4493928A1 (en) * | 2022-04-19 | 2025-01-22 | Firmenich Incorporated | Reduction of bitter taste of active pharmaceutical ingredients and related assays and screening methods |
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| JPS5825980B2 (ja) | 1976-02-12 | 1983-05-31 | ヤマサ醤油株式会社 | サイクリックヌクレオチドの定量法 |
| WO1990005745A1 (en) * | 1988-11-18 | 1990-05-31 | The General Hospital Corporation | A cAMP-RESPONSIVE TRANSCRIPTIONAL ENHANCER BINDING PROTEIN |
| US5462856A (en) | 1990-07-19 | 1995-10-31 | Bunsen Rush Laboratories, Inc. | Methods for identifying chemicals that act as agonists or antagonists for receptors and other proteins involved in signal transduction via pathways that utilize G-proteins |
| IL148593A0 (en) | 1999-09-10 | 2002-09-12 | Univ California | T2r, a novel family of taste receptors |
| US6558910B2 (en) | 1999-09-10 | 2003-05-06 | The Regents Of The University Of California | SF, a novel family of taste receptors |
| JP2003530098A (ja) * | 2000-04-07 | 2003-10-14 | セノミックス、インコーポレイテッド | Ｔ２ｒ味覚受容体及びそれをコードする遺伝子 |
| TW201022287A (en) * | 2001-01-03 | 2010-06-16 | Senomyx Inc | T1R taste receptors and genes encoding same |
| US7022488B2 (en) | 2003-02-03 | 2006-04-04 | Senomyx, Inc. | Functional coupling of T1Rs and T2Rs by Gi proteins, and cells-based assays for the identification of T1R and T2R modulators |
| US7413535B2 (en) * | 2001-07-27 | 2008-08-19 | Illinois Tool Works Inc. | Method for manufacturing tamper evident reclosable plastic bags |
| EP2270154A3 (en) | 2002-09-25 | 2011-08-10 | Deutsches Institut für Ernährungsforschung Potsdam-Rehbrücke | Bitter taste receptors |
| AU2003286069A1 (en) * | 2002-12-18 | 2004-07-09 | Givaudan Sa | Chimeric alpha q-gustducin g-proteins |
| EP1644528A2 (en) | 2003-06-19 | 2006-04-12 | THE GOVERNMENT OF THE UNITED STATES OF AMERICA, as represented by THE SECRETARY, the Department of Health and Human Services, | Variants of human taste receptor genes |
| KR20070053659A (ko) * | 2004-04-20 | 2007-05-25 | 도이체스 인스티튜트 퓌어 에른에룬그스포슝 | 쓴맛 수용체의 작용제 및 그의 용도 |
| US7829299B2 (en) | 2004-11-18 | 2010-11-09 | Deutsches Institut fur Ernahrungforschung Potsdam-Rehbrucke Stiftung des Offentlichen Rechts | Agonists of bitter taste receptors and uses thereof |
| JP4688517B2 (ja) * | 2005-02-15 | 2011-05-25 | 小川香料株式会社 | 高甘味度甘味料の呈味改善剤 |
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| US8187822B2 (en) | 2012-05-29 |
| US20100129833A1 (en) | 2010-05-27 |
| US8597896B2 (en) | 2013-12-03 |
| EP2137322B1 (en) | 2013-02-27 |
| JP2010522541A (ja) | 2010-07-08 |
| WO2008119195A1 (en) | 2008-10-09 |
| US20120237953A1 (en) | 2012-09-20 |
| KR20100016044A (ko) | 2010-02-12 |
| EP2137322A1 (en) | 2009-12-30 |
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