JP5464311B2 - ルシフェラーゼの発光基質 - Google Patents

ルシフェラーゼの発光基質 Download PDF

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Publication number
JP5464311B2
JP5464311B2 JP2008023396A JP2008023396A JP5464311B2 JP 5464311 B2 JP5464311 B2 JP 5464311B2 JP 2008023396 A JP2008023396 A JP 2008023396A JP 2008023396 A JP2008023396 A JP 2008023396A JP 5464311 B2 JP5464311 B2 JP 5464311B2
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Japan
Prior art keywords
compound
luminescent
mmol
acid
firefly
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JP2008023396A
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English (en)
Japanese (ja)
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JP2009184932A (ja
JP2009184932A5 (https=
Inventor
昌次郎 牧
哲 小島
治樹 丹羽
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
THE UNIVERSITY OF ELECTRO-COMUNICATINS
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THE UNIVERSITY OF ELECTRO-COMUNICATINS
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Application filed by THE UNIVERSITY OF ELECTRO-COMUNICATINS filed Critical THE UNIVERSITY OF ELECTRO-COMUNICATINS
Priority to JP2008023396A priority Critical patent/JP5464311B2/ja
Priority to PCT/JP2009/000376 priority patent/WO2009096197A1/ja
Priority to US12/865,328 priority patent/US8709821B2/en
Publication of JP2009184932A publication Critical patent/JP2009184932A/ja
Publication of JP2009184932A5 publication Critical patent/JP2009184932A5/ja
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/56—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09K—MATERIALS FOR MISCELLANEOUS APPLICATIONS, NOT PROVIDED FOR ELSEWHERE
    • C09K11/00—Luminescent materials, e.g. electroluminescent or chemiluminescent
    • C09K11/06—Luminescent materials, e.g. electroluminescent or chemiluminescent containing organic luminescent materials
    • C09K11/07—Luminescent materials, e.g. electroluminescent or chemiluminescent containing organic luminescent materials having chemically-interreactive components, e.g. reactive chemiluminescent compositions
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/21—Hydrocarbon
    • Y10T436/212—Aromatic
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/21—Hydrocarbon
    • Y10T436/214—Acyclic [e.g., methane, octane, isoparaffin, etc.]
    • Y10T436/216—Unsaturated [e.g., ethylene, diene, etc.]

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Materials Engineering (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Enzymes And Modification Thereof (AREA)
JP2008023396A 2008-02-02 2008-02-02 ルシフェラーゼの発光基質 Active JP5464311B2 (ja)

Priority Applications (3)

Application Number Priority Date Filing Date Title
JP2008023396A JP5464311B2 (ja) 2008-02-02 2008-02-02 ルシフェラーゼの発光基質
PCT/JP2009/000376 WO2009096197A1 (ja) 2008-02-02 2009-02-02 ルシフェラーゼの発光基質
US12/865,328 US8709821B2 (en) 2008-02-02 2009-02-02 Luminescent substrate for liciferase

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2008023396A JP5464311B2 (ja) 2008-02-02 2008-02-02 ルシフェラーゼの発光基質

Publications (3)

Publication Number Publication Date
JP2009184932A JP2009184932A (ja) 2009-08-20
JP2009184932A5 JP2009184932A5 (https=) 2011-02-17
JP5464311B2 true JP5464311B2 (ja) 2014-04-09

Family

ID=40912551

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2008023396A Active JP5464311B2 (ja) 2008-02-02 2008-02-02 ルシフェラーゼの発光基質

Country Status (3)

Country Link
US (1) US8709821B2 (https=)
JP (1) JP5464311B2 (https=)
WO (1) WO2009096197A1 (https=)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5550035B2 (ja) * 2009-03-17 2014-07-16 国立大学法人電気通信大学 波長が制御されたルシフェラーゼの発光基質および製造方法
CN103796999B (zh) * 2011-08-24 2015-07-22 国立大学法人电气通信大学 荧光素酶的发光基质
JP6495232B2 (ja) 2013-03-12 2019-04-03 プロメガ コーポレイションＰｒｏｍｅｇａ Ｃｏｒｐｏｒａｔｉｏｎ 赤方偏移ルシフェリン及びその使用方法
JP6011974B2 (ja) * 2013-05-07 2016-10-25 国立大学法人電気通信大学 新規ハロゲン化水素塩
JP6353751B2 (ja) * 2013-09-25 2018-07-04 国立大学法人電気通信大学 新規複素環式化合物及びその塩、並びに、発光基質組成物
JPWO2021193069A1 (https=) * 2020-03-23 2021-09-30
CN115996914B (zh) * 2020-06-29 2024-06-07 国立大学法人电气通信大学 新型杂环化合物及其盐、以及发光底物组合物
WO2022050233A1 (ja) * 2020-09-03 2022-03-10 黒金化成株式会社 発光システム及びシトクロムｐ４５０の定量方法
JPWO2023238683A1 (https=) * 2022-06-06 2023-12-14
CN117603158A (zh) * 2023-12-01 2024-02-27 广州优南科技有限公司 一种d-荧光素以及d-荧光素钾盐的制备方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3164597A (en) * 1962-12-17 1965-01-05 Geigy Chem Corp 5-carboxylic acid-2-phenyl-pyrrolines, corresponding pyrrolidines and functional derivatives thereof
JPS4730183B1 (https=) * 1970-09-16 1972-08-07
JP2002080476A (ja) * 2000-08-31 2002-03-19 Iatron Lab Inc Ｄ−ルシフェリン類縁体並びにルシフェラーゼ活性分析用試薬及びａｔｐ分析用試薬
JP2006219381A (ja) * 2005-02-08 2006-08-24 Univ Of Electro-Communications 複素環化合物及び発光甲虫ルシフェラーゼ発光系用発光基質
EP2272972A1 (en) 2005-05-31 2011-01-12 Promega Corporation Luminogenic and fluorogenic compounds and methods to detect molecules or conditions
JP4899046B2 (ja) * 2005-09-30 2012-03-21 国立大学法人 東京大学 新規ルシフェリン誘導体
JP4730183B2 (ja) 2006-04-17 2011-07-20 株式会社日立製作所 映像表示装置

Also Published As

Publication number Publication date
WO2009096197A1 (ja) 2009-08-06
JP2009184932A (ja) 2009-08-20
US20110033878A1 (en) 2011-02-10
US8709821B2 (en) 2014-04-29

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