JP5461408B2 - 二重弁システム付き使い捨て注入装置 - Google Patents
二重弁システム付き使い捨て注入装置 Download PDFInfo
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- JP5461408B2 JP5461408B2 JP2010527070A JP2010527070A JP5461408B2 JP 5461408 B2 JP5461408 B2 JP 5461408B2 JP 2010527070 A JP2010527070 A JP 2010527070A JP 2010527070 A JP2010527070 A JP 2010527070A JP 5461408 B2 JP5461408 B2 JP 5461408B2
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- Prior art keywords
- pump
- valve
- valves
- container
- actuator
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- 238000001802 infusion Methods 0.000 title claims description 16
- 239000000126 substance Substances 0.000 claims description 40
- 239000003814 drug Substances 0.000 claims description 26
- 229940079593 drug Drugs 0.000 claims description 22
- 230000007246 mechanism Effects 0.000 claims description 12
- 238000012546 transfer Methods 0.000 claims description 4
- 239000000243 solution Substances 0.000 description 36
- 239000012530 fluid Substances 0.000 description 32
- NOESYZHRGYRDHS-UHFFFAOYSA-N insulin Chemical compound N1C(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(NC(=O)CN)C(C)CC)CSSCC(C(NC(CO)C(=O)NC(CC(C)C)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CCC(N)=O)C(=O)NC(CC(C)C)C(=O)NC(CCC(O)=O)C(=O)NC(CC(N)=O)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CSSCC(NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2C=CC(O)=CC=2)NC(=O)C(CC(C)C)NC(=O)C(C)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2NC=NC=2)NC(=O)C(CO)NC(=O)CNC2=O)C(=O)NCC(=O)NC(CCC(O)=O)C(=O)NC(CCCNC(N)=N)C(=O)NCC(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC(O)=CC=3)C(=O)NC(C(C)O)C(=O)N3C(CCC3)C(=O)NC(CCCCN)C(=O)NC(C)C(O)=O)C(=O)NC(CC(N)=O)C(O)=O)=O)NC(=O)C(C(C)CC)NC(=O)C(CO)NC(=O)C(C(C)O)NC(=O)C1CSSCC2NC(=O)C(CC(C)C)NC(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CC(N)=O)NC(=O)C(NC(=O)C(N)CC=1C=CC=CC=1)C(C)C)CC1=CN=CN1 NOESYZHRGYRDHS-UHFFFAOYSA-N 0.000 description 20
- 102000004877 Insulin Human genes 0.000 description 10
- 108090001061 Insulin Proteins 0.000 description 10
- 229940125396 insulin Drugs 0.000 description 10
- 230000000994 depressogenic effect Effects 0.000 description 9
- 230000008901 benefit Effects 0.000 description 8
- 238000012377 drug delivery Methods 0.000 description 7
- 239000007788 liquid Substances 0.000 description 6
- 238000004891 communication Methods 0.000 description 5
- 239000000463 material Substances 0.000 description 5
- 230000009471 action Effects 0.000 description 4
- 239000002313 adhesive film Substances 0.000 description 4
- 238000004519 manufacturing process Methods 0.000 description 4
- 239000012528 membrane Substances 0.000 description 3
- 239000000356 contaminant Substances 0.000 description 2
- 238000010586 diagram Methods 0.000 description 2
- 230000006872 improvement Effects 0.000 description 2
- 238000007726 management method Methods 0.000 description 2
- 235000012054 meals Nutrition 0.000 description 2
- 238000000034 method Methods 0.000 description 2
- 238000012986 modification Methods 0.000 description 2
- 230000004048 modification Effects 0.000 description 2
- 238000003032 molecular docking Methods 0.000 description 2
- 238000003825 pressing Methods 0.000 description 2
- 230000004044 response Effects 0.000 description 2
- 235000011888 snacks Nutrition 0.000 description 2
- 238000010254 subcutaneous injection Methods 0.000 description 2
- 239000007929 subcutaneous injection Substances 0.000 description 2
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 description 1
- 102000016261 Long-Acting Insulin Human genes 0.000 description 1
- 108010092217 Long-Acting Insulin Proteins 0.000 description 1
- 229940100066 Long-acting insulin Drugs 0.000 description 1
- 108010026951 Short-Acting Insulin Proteins 0.000 description 1
- 229940123958 Short-acting insulin Drugs 0.000 description 1
- 206010067584 Type 1 diabetes mellitus Diseases 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 239000008280 blood Substances 0.000 description 1
- 210000004369 blood Anatomy 0.000 description 1
- 230000007423 decrease Effects 0.000 description 1
- 230000000881 depressing effect Effects 0.000 description 1
- 238000011161 development Methods 0.000 description 1
- 239000008103 glucose Substances 0.000 description 1
- 230000003862 health status Effects 0.000 description 1
- 238000002347 injection Methods 0.000 description 1
- 239000007924 injection Substances 0.000 description 1
- 230000003993 interaction Effects 0.000 description 1
- 206010033675 panniculitis Diseases 0.000 description 1
- 238000005086 pumping Methods 0.000 description 1
- 239000011435 rock Substances 0.000 description 1
- 210000004304 subcutaneous tissue Anatomy 0.000 description 1
- 238000002560 therapeutic procedure Methods 0.000 description 1
- 208000001072 type 2 diabetes mellitus Diseases 0.000 description 1
- 230000000007 visual effect Effects 0.000 description 1
Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/142—Pressure infusion, e.g. using pumps
- A61M5/14244—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body
- A61M5/14248—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body of the skin patch type
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/142—Pressure infusion, e.g. using pumps
- A61M5/14212—Pumping with an aspiration and an expulsion action
- A61M5/1424—Manually operated pumps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/142—Pressure infusion, e.g. using pumps
- A61M5/145—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons
Landscapes
- Health & Medical Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Veterinary Medicine (AREA)
- Hematology (AREA)
- Vascular Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Dermatology (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
- External Artificial Organs (AREA)
Description
12、212 包囲体
14、214 ベース
16、216 第1のアクチュエータ制御ボタン
18、218 第2のアクチュエータ制御ボタン
22、222 容器
24、224 ポンプ
30、230 カニューレ
32、232 第1の弁
34、234 第2の弁
50、250 出口
52,252 第1のリンケージ
54、254 第2のリンケージ
231 シャトル弁
420 ロックアウト機構
440 注入口
Claims (12)
- 薬液を保持する容器と、
前記薬液を患者に送出する出口と、
前記容器から受ける前記薬液を保持し、動作時に該薬液のほぼすべてを移すポンプと、
第1の位置と第2の位置との間で可動の第1の制御手段であって前記第1の位置にあるとき前記容器と前記ポンプとの間で第1の第1の流路を形成し、前記第2の位置にあるとき前記ポンプと前記出口との間で第2の流路を形成する第1の制御手段と、
前記第1の制御手段によって前記第2の流路が形成されているときにのみ、前記ポンプを作動させる第2の制御手段とを含み、
さらに、前記第1及び第2の流路を形成するための前記第1の制御手段によって操作可能の第1の弁及び第2の弁を含み、
前記両弁は、同時の開放が妨げられるように設定されており、
前記第1の制御手段は第1のアクチュエータ制御ボタンであり、前記第1の位置は非押下位置であり、前記第2の位置は押下位置であり、前記第2の制御手段は第2のアクチュエータ制御ボタンであり、
前記第1のアクチュエータ制御ボタンおよび前記第2のアクチュエータ制御ボタンが同時に押下された場合に、前記ポンプが作動させられて、前記出口から前記薬液が患者に送出させられる、着用可能な注入装置。 - さらに、前記両弁の同時開放を妨げる該両弁間のリンケージを含む、請求項1に記載の装置。
- 前記リンケージはトグル機構である、請求項2に記載の装置。
- 前記トグル機構は前記第1の制御手段に直接に結合されている、請求項3に記載の装置。
- 前記第1及び第2の弁はシャトル弁から成る、請求項1に記載の装置。
- 前記シャトル弁は前記第1の制御手段に直接に結合されている、請求項5に記載の装置。
- 前記第1及び第2の弁は前記ポンプから独立して操作可能である、請求項1に記載の装置。
- 前記両弁及びポンプは前記第1及び第2の制御手段に適用される手動力によってのみ、動作可能である、請求項1に記載の装置。
- 前記第1及び第2の弁の一方は、前記容器からの圧力上昇につれて、より強固に閉鎖するシールを提供する安全弁である、請求項1に記載の装置。
- 前記第1及び第2の弁の前記一方の弁は前記容器と前記出口との間にある、請求項9に記載の装置。
- 前記ポンプは、ピストン及びシリンダを含むピストンポンプであり、前記ピストンが前記第2の制御手段に直接結合される、請求項1に記載の装置。
- 前記第1及び第2の弁の一方は、前記ポンプからの圧力上昇につれて、より強固に閉鎖するシールを提供する、請求項1に記載の装置。
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US11/906,130 | 2007-09-28 | ||
US11/906,130 US8226607B2 (en) | 2007-09-28 | 2007-09-28 | Disposable infusion device with dual valve system |
US11/906,126 US8128596B2 (en) | 2007-09-28 | 2007-09-28 | Disposable infusion device layered structure |
PCT/US2008/077314 WO2009045776A2 (en) | 2007-09-28 | 2008-09-23 | Disposable infusion device with dual valve system |
Publications (2)
Publication Number | Publication Date |
---|---|
JP2010540093A JP2010540093A (ja) | 2010-12-24 |
JP5461408B2 true JP5461408B2 (ja) | 2014-04-02 |
Family
ID=40601195
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2010527070A Active JP5461408B2 (ja) | 2007-09-28 | 2008-09-23 | 二重弁システム付き使い捨て注入装置 |
Country Status (7)
Country | Link |
---|---|
US (2) | US8226607B2 (ja) |
EP (1) | EP2197517B8 (ja) |
JP (1) | JP5461408B2 (ja) |
CN (1) | CN101808681B (ja) |
CA (1) | CA2739183C (ja) |
IL (1) | IL204733A (ja) |
WO (2) | WO2009045776A2 (ja) |
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EP2197517B1 (en) | 2019-04-17 |
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US8128596B2 (en) | 2012-03-06 |
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