JP5451041B2 - デンドリマー化合物、デンドリマー錯体及びｍｒｉ造影剤 - Google Patents

デンドリマー化合物、デンドリマー錯体及びｍｒｉ造影剤 Download PDF

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Publication number
JP5451041B2
JP5451041B2 JP2008306627A JP2008306627A JP5451041B2 JP 5451041 B2 JP5451041 B2 JP 5451041B2 JP 2008306627 A JP2008306627 A JP 2008306627A JP 2008306627 A JP2008306627 A JP 2008306627A JP 5451041 B2 JP5451041 B2 JP 5451041B2
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Japan
Prior art keywords
group
complex
formula
compound
dendrimer
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JP2008306627A
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English (en)
Japanese (ja)
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JP2009221187A5 (enExample
JP2009221187A (ja
Inventor
輝幸 近藤
寛 辻田
アベデン シデイキ ザイヌル
伸悟 松木
大樹 三浦
豪人 杤尾
哲也 松田
美智子 楢崎
英寿 都築
克明 久家
佳紀 富田
公博 吉村
哲哉 矢野
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Canon Inc
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Canon Inc
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Priority to JP2008306627A priority Critical patent/JP5451041B2/ja
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Publication of JP2009221187A5 publication Critical patent/JP2009221187A5/ja
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic Table
    • C07F5/003—Compounds containing elements of Groups 3 or 13 of the Periodic Table without C-Metal linkages
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A61K49/08—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
    • A61K49/10—Organic compounds
    • A61K49/101—Organic compounds the carrier being a complex-forming compound able to form MRI-active complexes with paramagnetic metals
    • A61K49/106—Organic compounds the carrier being a complex-forming compound able to form MRI-active complexes with paramagnetic metals the complex-forming compound being cyclic, e.g. DOTA
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D255/00—Heterocyclic compounds containing rings having three nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D249/00 - C07D253/00
    • C07D255/02—Heterocyclic compounds containing rings having three nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D249/00 - C07D253/00 not condensed with other rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D257/00—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
    • C07D257/02—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D259/00—Heterocyclic compounds containing rings having more than four nitrogen atoms as the only ring hetero atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Radiology & Medical Imaging (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
JP2008306627A 2007-11-29 2008-12-01 デンドリマー化合物、デンドリマー錯体及びｍｒｉ造影剤 Active JP5451041B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2008306627A JP5451041B2 (ja) 2007-11-29 2008-12-01 デンドリマー化合物、デンドリマー錯体及びｍｒｉ造影剤

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
JP2007309087 2007-11-29
JP2007309087 2007-11-29
JP2008040990 2008-02-22
JP2008040990 2008-02-22
JP2008306627A JP5451041B2 (ja) 2007-11-29 2008-12-01 デンドリマー化合物、デンドリマー錯体及びｍｒｉ造影剤

Publications (3)

Publication Number Publication Date
JP2009221187A JP2009221187A (ja) 2009-10-01
JP2009221187A5 JP2009221187A5 (enExample) 2012-01-26
JP5451041B2 true JP5451041B2 (ja) 2014-03-26

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JP2008306627A Active JP5451041B2 (ja) 2007-11-29 2008-12-01 デンドリマー化合物、デンドリマー錯体及びｍｒｉ造影剤

Country Status (3)

Country Link
US (2) US8772475B2 (enExample)
JP (1) JP5451041B2 (enExample)
WO (1) WO2009069833A1 (enExample)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2012070681A1 (ja) * 2010-11-26 2012-05-31 国立大学法人九州大学 常磁性を有する水溶性ハイパーブランチポリマー
JPWO2017170884A1 (ja) * 2016-03-31 2019-02-14 富士フイルム富山化学株式会社 新規なヒドロキサム酸誘導体の製造方法およびその中間体

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6039931A (en) * 1989-06-30 2000-03-21 Schering Aktiengesellschaft Derivatized DTPA complexes, pharmaceutical agents containing these compounds, their use, and processes for their production
US5695739A (en) 1989-06-30 1997-12-09 Schering Aktiengesellschaft Derivatized DTPA complexes, pharmaceutical agents containing these compounds, their use, and processes for their production
IT1291624B1 (it) 1997-04-18 1999-01-11 Bracco Spa Chelati complessi di metalli paramagnetici a bassa tossicita'
JP4954165B2 (ja) 2007-09-07 2012-06-13 キヤノン株式会社 化合物、診断薬、核磁気共鳴分析方法、核磁気共鳴イメージング方法、質量分析方法及び質量分析イメージング方法
JP5448397B2 (ja) 2007-09-07 2014-03-19 キヤノン株式会社 基質プローブ、多重核磁気共鳴法による酵素活性の検出方法および酵素活性のイメージング方法

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US20110028713A1 (en) 2011-02-03
US8772475B2 (en) 2014-07-08
JP2009221187A (ja) 2009-10-01
US20140275521A1 (en) 2014-09-18
US9115153B2 (en) 2015-08-25
WO2009069833A1 (en) 2009-06-04

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